Research - Publications

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244. Bong J-H, Lee SJ, Jung J, Sung JS, Kang M-J, Kim HO, Lee M, Jose J, Pyun J-C (2024) Surface Plasmon Resonance (SPR) Biosensor for the Detection of SARS‑CoV‑2 Using Autodisplyaed FV‑antibodies on Outer Membrane of E. coli, BioChip J, 18:146-159, IF: 4.3
243. Jung J, Sung JS, Kim T-H, Kang M-J, Jose J, Shin H-J, Pyun J-C (2024) One‑Step Immunoassay for the Detection of SARS‑CoV‑2 Nucleocapsid Protein Using Screened Fv‑Antibodies, BioChip J, published online 4.3
242. Haidar S, Amesty A, Oramos-Royo S, Götz C, El-Awaad E, Kaiser J, Bödecker S, Arnold A, Aichele D, Amaro-Luis JM, Estévez-Braun A, Jose J (2024) 1,2,3-Triazole-totarol conjugates as potent PIP5K1α lipid kinase inhibitors, Bioorg Med Chem, 105:117727, IF: 3.5
241. Kohlmann P, Krylov S, Marchand P, Jose J (2024) FRET assays for the identification of C. albicans HSP90-Sba1 and human HSP90α-p23 binding inhibitors, Pharmaceuticals, 17:516, IF: 4.6
240. Schreiber S, Gercke D, Lenz F, Jose J (2024) Application of an alchemical free energy method for the prediction of thermostable DuraPETase variants, Appl Microbiol Biotechnol, 108:305, IF: 5.0
239.  Hardebeck S, Jácobo Goebbels N, Michalski C, Schreiber S, Jose J (2024) Identification of a potent PCNA-p15-interaction inhibitor by Autodisplay based Peptide Library Screening, Microb Biotechnol, 17:e14471, IF: 5.7
238. Sung JS, Han Y, Yun TG, Jung J, Kim T-H, Piccinini F, Kang M-J, Jose J, Lee M, Pyun J-C (2024) Monocarboxylate transporter-1 (MCT-1) inhibitors screened from autodisplayed FV-antibody library, Int J Biol Macromol, 265:130854., IF: 8.2
237. Bong J-H, Dombovski A, Birus R, Cho S, Lee M, Pyun J-C, Jose J (2024) Covalent Coupling of Functionalized Outer Membrane Vesicles (OMVs) to Gold Nanoparticles, J Colloid Interface Sci, 663:227-237., IF: 9.9
236. Dombovski A, Steigerwald R, Ritter N, Disse P, Goerges G, Osthues J, Aymanns I, Dilkaute C, Schreiber J, Düfer M, Seebohm G, Wünsch B, Jose J (2024) A novel fluorescent labeling compound for GluN2A containing N-methyl-D-aspartate receptors identified by Autodisplay-based screening, J Pharm Anal, accepted
235. Sung JS, Kim S, Jung J, Kim T-H, Kwon S, Bae HE, Kang M-J, Jose J, Lee M, Pyun J-C (2024) Monoamine Oxidase‑A (MAO-A) Inhibitors Screened from the Autodisplayed Fv-Antibody Library, ACS Pharmacol Transl Sci, 7:150-160., IF: 6.0
234. Saenger T, Schulte MF, Vordenbäumen S, Herrmann FC, Bertelsbeck J, Meier K, Bleck E, Schneider M, Jose J (2024) Structural analysis of breast-milk αS1-casein: an α-helical conformation is required for TLR4-stimulation, Int J Mol Sci, 25:1743, IF: 5.6
233. Gesing K, Lenz F, Schreiber S, Kasimir M, Humpf H-U, Jose J (2023) Surface display and engineering of laccase CotA for increased growth of Pseudomonas putida on lignin, ChemCatChem, 16, e202301055., IF: 4.5
232. Gercke D, Lenz F, Jose J (2023) Split-GFP complementation at the bacterial cell surface for antibody-free labeling and quantification of heterologous protein display, Enzyme Microb Technol, 174:110391., IF: 3.4
231. Sung JS, Jung J, Hwang H, Bong J-H, Kang M-J, Jose J, Lee M, Pyun J-C (2023) Screening of Pancreatic Ribonuclease A Inhibitors from an Autodisplayed Fv-Antibody Library, ACS Pharmacol Transl Sci, 6:1945–1957., IF: 6.0
230. Jung J, Sung JS, Bong J-H, Kim T-H, Kwon S, Bae HE, Kang M-J, Jose J, Lee M, Shin H-J, Pyun J-C (2023) One-step immunoassay of SARS-CoV-2 using screened Fv-antibodies and switching peptides, Biosens Bioelectron, 245:115834., IF: 12.6
229. Possart K, Herrmann FC, Jose J, Schmidt TJ (2023) In Silico and In Vitro Search for Dual Inhibitors of the Trypanosoma brucei and Leishmania major Pteridine Reductase 1 and Dihydrofolate Reductase, Molecules, 28:7526., IF: 4.6
228. Wegner T†, Dombovski A†, Gesing K, Köhrer A, Elinkmann M, Karst U, Glorius F, Jose J (2023) Combining lipid-mimicking-enabled transition metal and enzyme
mediated catalysis at the cell surface of E. coli, Chem Sci, 14:11896 – 11906., IF: 8.4
† These authors contributed equally to this work
227. Bong J-H, Birus R, Dombovski A, Pyun J-C, Jose J (2023) Development of Novel Outer Membrane Vesicle-Nanoparticles (Omv-Nps) Using Bioorthogonal Chemistry, SSRN.
226. Hardebeck S, Schreiber S, Adick A, Langer K, Jose J (2023) A FRET based assay for the identification of PCNA inhibitors, Int J Mol Sci, 24:11858., IF: 5.6
225. Hardebeck S, Schreiber S, Adick A, Langer K, Jose J (2023) A FRET based assay for the identification of PCNA inhibitors,, 2023070433.
224. Gasse C, Srivastava P, Shepers G, Jose J, Hollenstein M, Marlière P, Herdewijn P (2023) Controlled E. coli aggregation mediated by DNA and XNA hybridization, ChemBioChem, 24:e202300191., IF: 3.2
223. López-Rojas P, Haidar S, Jürgens FM, Aichele D, Amesty A, Estévez-Braun A, Jose J (2023) Synthesis and biological evaluation of anthracene-9,10 dione derivatives as CK2 inhibitors, Results Chem, 6:100997., IF: 2.3
222. Jung J, Bong J-H, Soo Sung J, Park J-H, Kim T-H, Kwon S, Kang M-J, Jose J, Pyun J-C (2023) Immunoaffinity biosensors for the detection of SARS-CoV-1 using screened Fv-antibodies from an autodisplayed Fv-antibody library, Biosens Bioelectron, 115439., IF: 12.6
221. Wojciechowski MN, Schreiber S, Jose J (2023) A Novel Flow Cytometry-Based Assay for the Identification of HCN4 CNBD Ligands, Pharmaceuticals, 16:710., IF: 5.215
220. Kim SG, Kim JY, Kim MY, Park J-M, Jose J, Park M (2023) Autodisplay of streptococcal protein G for construction of an orientation-controlled immunoaffinity layer, RSC Analyst, 148:742-751., IF: 5.227
219. Nickelsen A, Götz C, Lenz F, Niefind K, König S, Jose J (2023) Analyzing the interactome of human CK2β in prostate carcinoma cells reveals HSP70-1 and Rho guanin nucleotide exchange factor 12 as novel interaction partners, FASEB Bioadv, 15:314-330., IF: 2.7
218. Goracci L, Nurisso A, Roussel E, Pérès B, Chaptal V, Falson P, Marminon C, Jose J, Le Borgne M, Boumendjel A (2023) Inhibitors of ABCG2-mediated multidrug resistance: Lead generation through computer-aided drug design, Eur J Med Chem, 248:115070., IF: 7.088
217. Sung JS, Bong J-H, Yun TG, Han Y, Park Y, Jung J, Lee SJ, Kang M-J, Jose J, Lee M, Pyun J-C (2022) Antibody-Mediated Screening of Peptide Inhibitors for Monoamine Oxidase-B (MAO-B) from an Autodisplayed FV Library, ACS Bioconjugate Chem, 33:1166–1178., IF: 6.069
216. Eenink BDG, Kaminski TS, Bornberg-Bauer E, Jose J, Hollfelder F, van Loo B (2022) Vector Redesign and In-Droplet Cell-Growth Improves Enrichment and Recovery in live Escherichia coli, Microb Biotechnol, 15:2845–2853., IF: 6.575

Jose J (2022) Es gilt, umzudenken: Über das Nachhaltigkeitspotential von Palmöl
Blog post in: Nach(haltig)­gedacht (Der Blog des Zentrums für Interdisziplinäre Nachhaltigkeitsforschung)

215. Bayart C, Mularoni A, Hemmani N, Kerachni S, Jose J, Gouet P, Paladino J, Le Borgne M (2022) Tetanus Toxin Fragment C: Structure, Drug Discovery Research and Production, Pharmaceuticals, 15:756., IF: 5.215
214. Bhatia S, Spanier L, Bickel D, Dienstbier N, Woloschin V, Vogt M, Pols H, Lungerich B, Reiners J, Aghaallaei N, Diedrich D, Frieg B, Schliehe-Diecks J, Bopp B, Lang F, Gopalswamy M, Loschwitz J, Bajoghli B, Skokowa J, Borkhardt A, Hauer J, Hansen F, Smits S, Jose J, Gohlke H, Kurz T (2022) Development of a First-in-Class Small Molecule Inhibitor of the C-terminal Hsp90 Dimerization, ACS Cent Sci, 8:636–655., IF: 18.728
Phoenix Pharmazie Wissenschaftspreis 2023
213. Tian H, Furtmann C, Lenz F, Srinivasamurthy V, Bornscheuer UT, Jose J (2022) Enzyme cascade converting cyclohexanol into εcaprolactone coupled with NADPH recycling using surface displayed alcohol dehydrogenase and cyclohexanone monooxygenase on E. coli, Microb Biotechnol, 15:2235–2249., IF: 6.575
212. Asif M, Kaygusuz E, Shinawi M, Nickelsen A, Hsieh T-C, Wagle P, Budde B, Hochscherf J, Abdullah U, Höning S, Nienberg C, Lindenblatt D, Noegel A, Altmüller J, Thiele H, Motameny S, Fleischer N, Segal I, Tinschert S, Samra N, Savatt J, Rudy N, De Luca C, Fortugno P, Krawitz P, Hurst A, Niefind K, Jose J, Brancati F,  Nürnberg P, Hussain MS (2022) De novo variants of CSNK2B cause a new intellectual disability-craniodigital syndrome by disrupting the canonical Wnt signaling pathway, Hum Genet Genom Adv, 3:100111.
211. Werner C, Gast A, Lindenblatt D, Nickelsen A, Niefind K, Jose J, Hochscherf J (2022) Structural and Enzymological Evidence for an Altered Substrate Specificity in Okur-Chung Neurodevelopmental Syndrome Mutant CK2αLys198Arg, Front Mol Biosci, 9:831693., IF: 6.113
210. Sung JS, Bong J-H, Lee SJ, Jung J, Kang M-J, Lee M, Shim W-B, Jose J, Pyung J-C (2022) One-step immunoassay for food allergens based on screened mimotopes from autodisplayed FV-antibody library, Biosens Bioelectron, 202:113976., IF: 12.545
209. Bhatia S, Spanier L, Bickel D, Dienstbier N, Woloschin V, Vogt M, Pols H, Lungerich B, Reiners J, Aghaallaei N, Diedrich D, Frieg B, Schliehe-Diecks J, Bopp B, Lang F, Gopalswamy M, Loschwitz J, Bajohgli B,  Skokowa J, Borkhardt A, Hauer J, Hansen FK, Smits SHJ, Jose J, Gohlke H, Kurz T (2021) Development of a first-in-class small molecule inhibitor of the c-terminal Hsp90 dimerization, ChemRxiv, published online.
208. Park J-M, Kim MY, Jose J, Park M (2021) Covalently Immobilized Regenerative Immunoaffinity Layer with Orientation-Controlled Antibodies Based on Z-domain Autodisplay, Int J Mol Sci, 23:459., IF: 6.208
207. Possart K, Herrmann FC, Jose J, Costi MP, Schmidt TJ (2021) Sesquiterpene Lactones with Dual Inhibitory Activity against the Trypanosoma brucei Pteridine Reductase 1 and Dihydrofolate Reductase, Molecules, 27:149., IF: 4.927
206. Palei S, Jose J, Mootz HD (2021) Preparation of Bacterial Cell-Surface Displayed Semisynthetic Cyclic Peptides, Methods Mol Biol, 2371:193-213.
205. Birus R, El-Awaad E, Alchab F, Aichele D, Ettouati L, Götz C, Le-Borgne M, Jose J (2021) 4,5,7-Trisubstituted Indeno [1,2-b]indole Inhibits CK2 Activity in Tumor Cells Equivalent to CX-4945 and Shows Strong Anti-Migratory Effects, FEBS Open Bio, 12:394-411., IF: 2.792
204. Jung J, Bong J-H, Sung JS, Lee SJ, Lee M, Kang M-J, Jose J*, Pyun J-C* (2021) Fluorescein and Rhodamine B-Binding Domains from Autodisplayed Fv-Antibody Library, ACS Bioconjugate Chem, 32:2213–2223., IF: 6.069
203. Haidar S, Jürgens F, Aichele D, Jagels A, Humpf H-U, Jose J (2021) Natural compounds isolated from Stachybotrys chartarum are potent inhibitors of human protein kinase CK2, Molecules, 26:4453., IF: 4.927
202. Rajan R, Schepmann D, Steigerwald R, Schreiber JA, El-Awaad E, Jose J, Seebohm G, Wünsch B (2021) [2.2]Paracyclophane-based TCN-201 analogs as GluN2A-selective NMDA receptor antagonists, ChemMedChem, 16:3201–3209., IF: 3.540
201. Lindenblatt D, Applegate V, Nickelsen A, Klußmann MJ, Neundorf I, Götz C, Jose J, Niefind K (2021) Molecular Plasticity of Crystalline CK2α‘ Leads to KN2, a Bivalent Inhibitor of Protein Kinase CK2 with Extraordinary Selectivity, J Med Chem, 65:1302–1312., IF: 8.039
200. Nickelsen A, Jose J (2021) Label-free flow cytometry-based enzyme inhibitor identification, Anal Chim Acta, 1179:338826., IF: 6.911
199. El-Awaad E, Birus R, Marminon C, Bouaziz Z, Ballentin L, Aichele D, Le Borgne M, Jose J (2021) Broad-Spectrum Anticancer Activity and Pharmacokinetic Properties of a Prenyloxy-Subsituted Ideno[1,2-b]indole Derivative, Discovered as CK2 Inhibitor, Pharmaceuticals, 14:542., IF: 5.215
198. Jung J, Bong J-H, Kim M-J,Lee SJ, Sung JS, Lee M, Kang M-J, Song J, Jose J, Pyun J-C (2021) Screening of Fv Antibodies with Specific Binding Activities to Monosodium Urate and Calcium Pyrophosphate Dihydrate Crystals for the Diagnosis of Gout and Pseudogout, ACS Appl Bio Mater, 4:3388-3397.
197. Gercke D, Furtmann C, Tozakidis IEP, Jose J (2021) Highly crystalline post-consumer PET waste hydrolysis by surface displayed PETase using a bacterial whole-cell biocatalyst, ChemCatChem, 13:3479–3489., IF: 5.501
Top Downloaded Article in 2021
196. Lee SJ, Bong J-H, Jung J, Sung SJ, Kang M-J, Jose J, Pyun J-C (2021) Screening of biotin-binding FV-antibodies from autodisplayed FV-library on E. coli outer membrane, Anal Chim Acta,  1169:338627., IF: 6.911
195. Guragossian N, Belhani B, Moreno A, Nunes M T, Gonzalez-Lobato L, Marminon C, Berthier L, Do Rocio Andrade Pires A, Özvegy-Laczka C, Sarkadi B, Terreux R, Bouaziz Z, Berredjem M, Jose J, Di Pietro A, Falson P, Le Borgne M (2021) Uncompetitive nanomolar dimeric indenoindole inhibitors of the human breast cancer resistance pump ABCG2, Eur J Med Chem, 211:113017., IF: 7.088
194. Bouzina A, Berredjem M, Nocentini A, Bua S, Bouaziz Z, Jose J, Le Borgne M, Marminon C, Gratteri P, Supuran CT (2021) Ninhydrins inhibit carbonic anhydrases directly binding to the metal ion, Eur J Med Chem, 209:112875., IF: 7.088
193. Kita DH, Guragossian N, Zattoni IF, Rotuno Moure V, Gomes de Moraes Rego F, Luscarghi S, Moulenat T, Belhani B, Picheth G, Bouacida S, Bouaziz Z, Marminon C, Berredjem M, Jose J, Brown Goncalvez M, Ambudkar SV, Valdameri G, Le Borgne M (2021) Mechanistic basis of breast cancer resistance protein (BCRP/ABCG2) inhibition by new indeno[1,2-b]indoles, Sci Rep, 11:1788., IF: 4.997
192. Haidar S, Jürgens F, Aichele D, Jose J (2021) In silico and In vitro Studies of Natural Compounds as Human CK2 Inhibitors, Curr Comput-Aided Drug Des, 17:323-331., IF: 1.639
191. Strätker K, Haidar S, Dubiel M, Estevez-Braun A, Jose J (2020) Autodisplay of human PIP5K1α lipid kinase on Escherichia coli and inhibitor testing, Enzyme Microb Technol, 143:109717., IF: 3.705
190. Lindenblatt D, Nickelsen A, Applegate V, Jose J, Niefind K (2020) Structural and mechanistic basis of the inhibitory potency of selected 2-aminothiazole compounds on protein kinase CK2, J Med Chem, 63:7766−7772., IF: 8.039
189. Spiegler V, Gierlikowska B, Saenger T, Addotey J, Sendker J, Jose J, Kiss AK, Hensel A (2020) Root Extracts from Ononis spinosa inhibit IL-8 Release via Interactions with Toll-like receptor 4 and Lipopolysaccharide, Front Pharmacol, 11:889., IF: 5.988
188. Lee GY, Bong JH, Jung J, Kang MJ, Jose J, Pyun J-C (2020) Application of a thermophoretic immunoassay in the diagnosis of lupus using outer membrane particles from E. coli, Biosens Bioelectron, 156:112110., IF: 12.545
187. Lengers I, Herrmann F, Le Borgne M, Jose J (2020) Improved surface display of human Hyal1 and identification of testosterone propionate and chicoric acid as new inhibitors, Pharmaceuticals, 13:54., IF: 5.215
186. Lenz F, Zurek P, Umlauf M, Tozakidis IEP, Jose J (2020) Tailor-made β-glucosidase with increased activity at lower temperature without loss of stability and glucose tolerance, Green Chem, 22:2234-2243., IF: 11.034
185. Kröger L, Daniliuc CG, Ensan D, Borgert S, Nienberg C, Lauwers M, Steinkrüger M, Jose J, Pietsch M, Wünsch B (2020) Synthesis and SAR of tetracyclic inhibitors of the kinase CK2 derived from furocarbazole W16, ChemMedChem, 15:871-881., IF: 3.540
184. Pietsch M, Viht K, Schnitzler A, Ekambaram R, Steinkrüger M, Enkvist E, Nienberg C, Nickelsen A, Lauwers M, Jose J, Uri A, Niefind K (2020) Unexpected CK2β-antagonistic functionality of bisubstrate inhibitors targeting protein kinase CK2, Bioorg Chem, 96:103608., IF: 5.307
183. Haidar S, Marminon C, Aichele D, Nacereddine A, Zeinyeh W, Bouzina A, Berredjem M, Ettouati L, Bouaziz Z, Le Borgne M, Jose J (2020) QSAR model of indeno[1,2-b]indole derivatives and identification of N-isopentyl-2-methyl-4,9-dioxo-4,9-dihydronaphtho[2,3-b]furan-3-carboxamide as potent CK2 inhibitor, Molecules, 25:97., IF: 4.927
182. Tozakidis IEP, Lüken LM, Üffing A, Meyers A, Jose J (2020) Improving the autotransporter-based surface display of enzymes in Pseudomonas putida KT2440, Microb Biotechnol, 13:176-184., IF: 6.575
181. Strätker K, Haidar S, Amesty A, El-Awaad E, Götz C, Estévez-Braun A, Jose J (2020) Development of an in vitro screening assay for PIP5K1α lipid kinase and identification of potent inhibitors, FEBS J, 287:3042-3064., IF: 5.622
180. Oramas-Royo S, Haidar S, Amesty A, Martín-Acosta P, Feresin G, Tapia A, Aichele D, Jose J, Estévez-Braun A (2019) Design, synthesis and biological evaluation of new embelin derivatives as CK2 inhibitors, Bioorg Chem, 95:103520., IF: 5.307
179. van Loo B, Heberlein M, Mair P, Zinchenko A, Schüürmann J, Eenink BDG, Holstein JM, Dilkaute C, Jose J, Hollfelder Fl, Bornberg-Nauer E (2019) High-Throughput, Lysis-free Screening for Sulfatase Activity Using Escherichia coli Autodisplay in Microdroplets, ACS Synth Biol, 8:2690-2700., IF: 5.249
178. Su W, Matsumoto S, Banine F, Srivastava T, Dean J, Foster S, Hammond B, Peters A, Girish K, Rangappa K, Basappa S, Jose J, Hennebold J, Murphy M, Bennet-Toomey J, Back S, Sherman L (2019) A modified flavonoid accelerates oligodendrocyte maturation and functional remyelination, Glia, 68:263-279., IF: 8.073
177. Meyers A, Furtmann C, Gesing K, Tozakidis IEP, Jose J (2019) Cell density-dependent auto-inducible promoters for expression of recombinant proteins in Pseudomonas putida, Microb Biotechnol, 12:1003-1013., IF: 6.575
176. Haidar S, Aichele D, Birus R, Hielscher J, Laitinen T, Poso A, Jose J (2019) In vitro and in silico evaluation of bikaverin as a potent inhibitor of human protein kinase CK2, Molecules, 24:1380., IF: 4.927
175. Oloketuyi S, Dilkaute C, Mazzega E, Jose J, de Marco A (2019) Purification-independent immunoreagents obtained by displaying nanobodies on bacteria surface, Appl Microbiol Biotechnol, 103:4443-4453., IF: 5.560
174 Addotey JN, Lengers I, Jose J, Hensel A (2019) Hyal-1 inhibitors from the leaves of Phyllanthus muellerianus (Kuntze) Excell, J Ethnopharmacol, 236:326-335., IF: 5.195
173. Lee G-Y, Bong J-H, Kim JY, Yoo G, Park M, Kang M-J, Jose J, Pyun J-C (2019) Thermophoretic diagnosis of autoimmune diseases based on Escherichia coli with autodisplayed autoantigens, Anal Chim Acta, 1055:106-114., IF: 6.911
172. Lindenblatt D, Nickelsen A, Applegate V, Hochscherf J, Witulski B, Bouaziz Z, Marminon C, Bretner M, Le Borgne M, Jose J, Niefind K (2019) Diacritic binding of an indenoindole inhibitor by CK2α paralogs explored by a reliable path of atomic resolution CK2α' structures, ACS Omega, 4:5471-5478., IF: 4.132
171. Saenger T, Vordenbäumen S, Genich S, Haidar S, Schulte M, Nienberg C, Bleck E, Schneider M, Jose J (2019) Human αS1-casein induces IL-8 secretion by binding to the ecto-domain of the TLR4/MD2 receptor complex, Biochim Biophys Acta-Gen Subj, 1863:632-643., IF: 4.117
170. Palei S, Becher KS, Nienberg C, Jose J, Mootz HD (2019) Bacterial Cell-Surface Display of Semisynthetic Cyclic Peptides, ChemBioChem, 20:72-77., IF: 3.468
169. Jeon D, Pyun J-C, Jose J, Park M (2018) A Regenerative Immunoaffinity Layer Based on the Outer Membrane of Z-Domains Autodisplaying E. coli for Immunoassays and Immunosensors, Sensors, 18:4030., IF: 3.847
168. Addotey JN, Lengers I, Jose J, Gampe N, Béni S, Petereit F, Hensel A (2018) Isoflavonids with inhibiting effects on human Hyaluronidase-1 and norneolignan Clitorienolactone B from Ononis spinosa L. root extract, Fitoterapia, 130:169-174., IF: 3.204
Most Downloaded Fitoterapia Article in October 2018
167. Esch S, König S, Bopp B, Jose J, Brandt S, Hensel A (2018) Cryptotanshinone from Salvia miltiorrhiza roots reduces cytokeratin CK1/10 expression in keratinocytes by activation of peptidyl-prolyl-cis-trans-isomerase FKBP1A, Planta Med, 85:552-562., IF: 3.007
166. Meyers A, Furtmann C, Jose J (2018) Direct optical density determination of bacterial cultures in microplates for high-throughput screening applications, Enzyme Microb Technol, 118:1-5., IF: 3.705
165. Bhatia S, Diedrich D, Frieg B, Stein S, Bopp B, Lang F, Zang T, Kröger T, Ernst T, Kögler G, Krieg A, Lüdeke S, Kunkel H, Rodrigques Moita AJ, Kassack MU, Marquardt V, Remke M, Grez M, Hochhaus A, Borkhardt A, Groth G, Nagle-Steger L, Jose J, Kurz T, Gohlke H, Hansen FK, Hauer J (2018) Targeting HSP90 dimerization via the C terminus is effective in imatinib-resistant CML and lacks the heat shock response, Blood, 132:307-320., IF: 25.669
164. Obeng EM, Brossette T, Ongkudon CM, Budiman C, Maas RM, Jose J (2018) The workability of Escherichia coli BL21 (DE3) and Pseudomonas putida KT2440 expression platforms with autodisplayed cellulases: a comparison, Appl Microbiol Biotechnol, 102:4829-4841., IF: 5.560
163. Sendker J, Böker I, Lengers I, Brandt S, Jose J, Stark T, Hofmann T, Fink C, Abdel-Aziz H, Hensel A (2018) Niedermolekulare Bestandteile reduzieren kurzkettige Hyaluronsäure-Moleküle, Pharmazeutische Zeitung, 163:43-47.
162. Obeng EM, Ongkudon CM, Budiman C, Maas R, Jose J (2018) An optimal blend of single autodisplayed cellulases for cellulose saccharification - a proof of concept, J Chem Technol Biotechnol, 93:2719-2728., IF: 3.709
161. Bloch S, Neman-Falenczyk B, Pierzynowska K, Piotrowska E, Wegrzyn A, Marminon C, Bouaziz Z, Nebois P, Jose J, Le Borgne M, Saso L, Wegrzyn G (2018) Inhibition of Shiga toxin-converting bacteriophage development by novel antioxidant compounds, J Enzym Inhib Med Chem, 33:639-650., IF: 5.756
160. Schnitzler A, Gratz A, Bollacke A, Weyrich M, Kuckländer U, Wünsch B, Götz C, Niefind K, Jose J (2018) A Π-halogen bond of dibenzofuranones with the gatekeeper Phe113 in human protein kinase CK2 leads to potent tight binding inhibitors, Pharmaceuticals, 11:23., IF: 5.215
159. Lee G-Y, Park M, Kang M-J, Jose J, Pyun J-C (2018) Thermophoretic immunoassay based on autodisplayed Z-domains for the detection of C-reactive protein, Sens Actuator B-Chem, 258:1131-1137., IF: 9.221
158. Nacereddine A, Bollacke A, Róka E, Marminon C, Bouaziz Z, Fenyvesi F, Bácskay IK, Jose J, Perret F, Le Borgne M (2018) Self-assembled supramolecular nanoparticles improve the cytotoxic efficacy of CK2 inhibitor THN7, Pharmaceuticals, 11:10., IF: 5.215
157. Martín-Acosta P, Haidar S, Amesty A, Aichele D, Jose J, Estévez-Braun A (2018) A new family of densely functionalized fused-benzoquinones as potent human protein kinase CK2 inhibitors, Eur J Med Chem, 144:410-423., IF: 7.088
156. Bong J-H, Song H-W, Kim T-H, Kang M-J, Jose J, Pyun J-C (2018) Refolding of autodisplayed anti-NEF scFv through oxidation with glutathione for immunosensors, Biosens Bioelectron, 102:600-609., IF: 12.545
155. Haidar S, Jabbour M, Al-Khayat MA, Aichele D, Jose J (2018) Synthesis and biological evaluation of novel 2(4'-hydroxynaphthyl)chromen-4-one as a CK2 inhibitor, Die Pharmazie, 73:191-195.
154. Park M, Pyun J-C, Jose J (2018) Orientation and density control of proteins on solid matters by outer membrane coating: Analytical and diagnostic applications, J Pharm Biomed Anal, 147:174-184., IF: 3.571
153. Motealleh A, Hermes H, Jose J, Kehr NS (2018) Chirality-dependent cell adhesion and enrichment in Janus nanocomposite hydrogels, Nanomed-Nanotechnol Biol Med, 14:247-256., IF: 6.458
152. Hochscherf J, Lindenblatt D, Witulski B, Birus R, Aichele D, Marminon C, Bouaziz Z, Le Borgne M, Jose J, Niefind K (2017) Unexpected binding mode of a potent indeno[1,2-b]indole-type inhibitor of protein kinase CK2 revealed by complex structures with the catalytic subunit CK2α and its paralog CK2α'. Pharmaceuticals, 10: 98.
151. Herrmann FC, Sivakumar N, Jose J, Costi MP, Pozzi C, Schmidt TJ (2017): In silico identification and in vitro evaluation of natural inhibitors of Leishmania major Pteridine reductase I. Molecules, 22: 2166
150. Koenig S, Altendorfer I, Saenger T, Bleck E, Vordenbäumen S, Schneider M, Jose J (2017) Ser71 of αS1-casein is phosphorylated in breast milk - Evidence from targeted mass analysis. Mol Nutr Food Res, 61: 1700496 doi:10.1002/mnfr.201700496.
149. Kehr S, Jose J (2017) Chirality-dependent cellular uptake of chiral nanocarriers and intracellular delivery of different amounts of guest molecules. Appl Surf Sci, 425:432-439.
148. Schulte MF, Tozakidis IE, Jose J (2017) Autotransporter-based surface display of hemicellulase on Pseudomonas putida: new whole-cell biocatalysts for the production of xylose from biomass. ChemCatChem, 9: 3955-3964.

Jose J, Le Borgne M, Pinna LA, Montenarh M (Eds.) (2017) An updated view on an emerging target: Selected papers from the 8th International Conference on Protein Kinases CK2. Pharmaceuticals, Special Issue. MDPI AG, Basel, Schweiz. ISBN 978-3-03842-412-3 (Pbk), ISBN 978-3-03842-413-0 (PDF).

146. Obeng EM, Adam SNN, Budiman C, Ongkudon CM, Maas R, Jose J (2017) Lignocellulases: a review of emerging and developing enzymes, systems, and practices. Bioresour Bioprocess 4:16.
145. Schüürmann J, Quehl P, Lindhorst F, Lang K, Jose J (2017) Autodisplay of glucose-6-phosphate dehydrogenase for redox cofactor regeneration at the cell surface. Biotech Bioeng, 114:1658-1669.
144. Pyun J-C, Jose J, Park M (2017) Development of a wash-free immunoassay using Escherichia coli cells with autodisplayed Z-domains. Analyst, 142:1720-28.
143. Jose J, Le-Borgne M, Pinna LA, Montenarh M (2017) Editorial. An updated view on an emerging target: Selected papers from the 8th International Conference on Protein Kinase CK2. Pharmaceuticals, 10: 33.
142. Sendker J, Böker I, Lengers I, Brandt S, Jose J, Stark T, Hofmann T, Fink C, Abdel-Aziz H, Hensel A (2017) Phytochemical characterization of low molecular constitutents from marshmallow roots (Althaea officinalis) and inhibiting effects of the aqueous extract on human hyaluronidase-1.   J Nat Prod, 80:290–297.
141. Yoo G, Bong J-H, Song H-W, Dilkaute C, Kang M-J, Jose J, Pyun J-C (2017) Autodisplay of the La/SSB protein on LPS-free E. Coli for the diagnosis of Sjögren's syndrome. Enzyme Microb Tech, 100:1-10.
140. Haidar S, Bouaziz Z, Marminon C, Laitinen T, Poso A, Le Borgne M, Jose J (2017) Development of pharmacophore model for indeno[1,2-b]indoles as human protein kinase CK2 inhibitors and database mining. Pharmaceuticals, 10: 8.
139. Nienberg C, Garmann C, Gratz A, Bollacke A, Götz C, Jose J (2017) Identification of a potent allosteric inhibitor of human protein kinase CK2 by bacterial surface display library screening. Pharmaceuticals, 10: 6.        TOP 10 most downloaded articles in Pharmaceuticals in 2017
138. Quehl P, Schüürmann J, Hollender J, Jose J (2017) Improving the activity of surface displayed cytochrome P450 enzymes by optimizing the outer membrane linker. BBA - Biomembranes, 1859:104-116.
137. Chang S-Y, Bong J-H, Yoo G, Lee M, Kang M-J, Jose J, Pyun J-C (2017) Activity control of autodisplayed proteins on the same outer membrane layer of E. coli by using Z-domain/streptavidin/and lipase/foldase systems. Enzyme Microb Technol, 96:85-95., IF: 3.4
136. Guragossian N, Gozzi GJ, Fouillet B, Gustin M-P, Terreux R, Bouaziz Z, Marminon C, Jose J, Di Pietro A, Pasanen M, Le Borgne M (2016) Candidate molecule selection based on in silico predicted ADMET properties of 12 indenoindole derivatives. Chem Informatics, 2:6.
135. Nienberg C, Retterath A, Becher K-S, Saenger T, Mootz HD, Jose J (2016) Site-specific labeling of protein kinase CK2: Combining surface display and click chemistry for drug discovery applications. Pharmaceuticals, 9: 36.
134. Tozakidis IEP, Brossette T, Lenz F, Maas R, Jose J (2016) Proof of concept for the simplified breakdown of cellulose by combining Pseudomonas putida strains with surface displayed thermophilic endocellulase, exocellulase and ß-glucosidase. Microb Cell Fact, 15:103.
133. Alchab F, Sibillie E, Ettouati L, Bana E, Bouaziz Z, Mularoni A, Monnio E, Bagrel D, Jose J, Le Borgne M, Chaimbault P (2016) Screening of indeno[1,2-b]indoloquinones by MALDI-MS: a new set of potential CDC25 phosphatase inhibitors brought to light. J Enz Inhib Med Chem, 31:25-32. 
132. Kim D-H, Bong J-H, Yoo G, Chang S-Y, Chang YW, Kang M-J, Jose J, Pyun J-C (2016) A magnetite suspension-based washing method for immuoassays using Escherichia coli with autodisplayed Z-domains. Enzyme Microb Tech, 92:1-8.
131. Vordenbäumen S, Saenger T, Braukmann A, Tahan T, Bleck E, Jose J, Schneider M (2016) Human casein alpha s1 induces proinflammatory cytokine expression in monocytic cells by TLR4-signaling. Mol Nutr Food Res, 60:1079-89.
130. Quehl P, Hollender J, Schüürmann J, Brossette T, Maas R, Jose J (2016) Co-expression of active human cytochrome P450 1A2 and cytochrome P450 reductase on the cell surface of Escherichia coli. Microb Cell Fact, 15:26.
129. Bopp B, Ciglia E, Ouald-Chaib A, Groth G, Gohlke H, Jose J (2016) Design and biological testing of peptidic dimerization inhibitors of human Hsp 90 that target the C-terminal domain. BBA General subjects, 1860:1043-1055.
128. Bollacke A, Nienberg C, Le Borgne M, Jose J (2016) Toward selective CK2alpha and CK2alpha’ inhibitors: Development of a novel whole-cell kinase assay by Autodisplay of catalytic CK2alpha’. J Pharm Biomed Anal, 121:253-260.
127. Le Borgne M, Haidar S, Duval O, Wünsch B, Jose J (2016) Proceedings of the 1st Joint European Conference on Therapeutic Targets and Medicinal Chemistry (TTMC 2015). Pharmaceuticals, 9: 1.
126. Kim DH, Bong JH, Yoo G, Chang SY, Park M, Chang YW, Kang MJ, Jose J, Pyun JC (2016) Microbead-based immunoassay using the outer membrane layer of Escherichia coli combined with autodisplay Z-domains. Appl Surf Sci 362:146-153.
125. Uttarkar S, Dassé E, Coulibaly A, Steinmann S, Jakobs A, Schomburg C, Trentmann A, Jose J, Schlenke P, Berdel WE, Schmidt TJ, Müller-Tidow C, Trampton J, Klempnauer KH (2016) Targeting acute myeloid leukemia with a small molecule inhibitor of the Myb/p300 interaction. Blood, 127:1173-1182.
124. Tozakidis IE, Quehl P, Schüürmann J, Jose J (2015) Let's do it outside: neue Biokatalysatoren mittels surface display. Biospektrum, 21:668-671.
123. Yoo G, Saenger T, Bong JH, Jose J, Kang MJ, Pyun JC (2015) Co-autodisplay of Z-domains and bovine caseins on the outer membrane of E. coli. BBA Biomembranes, 1848:3126-3133.
122. Herrmann FC, Lenz M, Jose J, Kaiser M, Brun R, Schmidt T (2015) In silico identification and in vitro activity of novel natural inhibitors of Trypanosoma brucei glyceraldehyde-3-phosphate-dehydrogenase. Molecules, 20:16154-16169.
121. Orlando Z, Lengers I, Melzig MF, Buschauer A, Hensel A, Jose J (2015) Autodisplay of human hyaluronidase Hyal-1 on Escherichia coli and identification of plant-derived enzyme inhibitors. Molecules, 20:15449-15468. 
120. Haidar S, Meyers A, Bollacke A, Jose J (2015) Synthesis and biological evaluation of 2,6-Di(furan-3-yl)anthracene-9,10-dione as an inhibitor of human protein kinase CK2. Die Pharmazie, 70:772-776.
119. Alchab F, Ettouati L, Bouaziz Z, Bollacke A, Delcros JG, Gertzen CGW, Gohlke H, Pinaud N, Marchivie M, Guillon J, Fenet B, Jose J, Le Borgne M (2015) Synthesis, biological evaluation and molecular modeling of substituted indeno[1,2-b]indoles as inhibitors of human protein kinase CK2. Pharmaceuticals, 8:279-302.
118. Gratz A, Bollacke A, Stephan S, Nienberg C, Le Borgne M, Götz C, Jose J (2015) Functional display of heterotetrameric human protein kinase CK2 on Escherichia coli: a novel tool for drug discovery. Microb Cell Fact, 14:74.
117. Gozzi GJ, Bouaziz Z, Winter E, Daflon-Yunes N, Honorat M, Guragossian N, Marminon C, Valdameri G, Bollacke A, Guillon J, Pinaud N, Marchivie M, Cadena SM,  Jose J, Le Borgne M, DiPietro A (2015) Phenolic indeno[1,2-b]indoles as ABCG2-selective potent and nontoxic . inhibitors stimulating basal ATPase activity. Drug Des Devel Ther, 9:3481-3495.
116. Yoo G, Bong MH, Park M, Jose J, Kang MJ, Pyun JC (2015) Electrochemical analysis of autodisplayed adrenodoxin (ADX) on the outer membrane of E. coli. BBA Biomembranes, 1848:1509-1513.
115. Sichwart S, Tozakidis IE, Teese M, Jose J (2015) Maximized autotransporter mediated expression (MATE) of surface display and secretion of recombinant proteins in Escherichia coli. Food Technol Biotechnol, 53:251-260.
114. Marminon C, Nacereddine A, Bouaziz Z, Nebois P, Jose J, Le Borgne M (2015) Microwave-assisted oxidation of Indan-1-ones into Ninhydrins. Tetrahedron Lett, 56:1840-1842.
113. Uttarkar S, Dukare S, Bopp B, Goblirsch M, Jose J, Klempnauer KH (2015) Naphtol AS-E phosphate inhibits the activity of the transcription factor Myb by blocking the interaction with the KIX domain of the coactivator p300. Mol Cancer Ther, 14:1276-1285.
112. Tozakidis IE, Sichwart S, Jose J (2015) Going beyond E. coli: Autotransporter based surface display on alternative host organisms. New  Biotechnol, 32:644-650.
 111. Gozzi GJ, Bouaziz Z, Winter E, Daflon-Yunes N, Aichele D, Nacereddine A, Marminon C, Valdameri G, Zeinyeh W, Bollacke A, Guillon J, Lacoudre A, Pinaud N, Cadena S, Jose J, Le Borgne M, Di Pietro A (2015) Converting potent indeno[1,2-b]indole inhibitors of protein kinase CK2
into selective inhibitors of the breast cancer resistance protein ABCG2.  J Med Chem, 58:265-277.
110. Park M, Yoo G, Bong JH, Jose J, Kang MJ, Pyun J-C (2015) Isolation and characterization of the outer membrane of Escherichia coli with autodisplayed Z-domains. BBA Biomembranes, 1848:842-847.
109. Altendorfer I, König S, Braukmann A, Saenger T, Bleck E, Vordenbäumen S, Kubiak A, Schneider M, Jose J (2014) Quantification of αS1-casein in breast milk using a targeted mass spectrometry-based approach. J Pharm Biomed Anal, 103:52-58.
108. Bong JH, Yoo BG, Park M, Kang MJ, Jose J, Pyun J-C (2014) Ultrasonic isolation of the outer membrane of Escherichia coli with autodisplayed Z-domains. Enzyme Microb Tech, 66:42-47.
107. Tozakidis IEP, Sichwart S, Teese G, Jose J (2014) Autotransporter mediated esterase display on Zymomonas mobilis and Zymobacter palmae. J Biotechnol, 191:228-235.
106. Schüürmann J, Quehl P, Festel G, Jose J (2014) Bacterial whole cell biocatalysts by surface display of enzymes: towards industrial application. Appl Microbiol Biotechnol, 98:8031-8046.
105. Gawarzewski I, DiMaio F, Winterer E, Tschapek B, Smits SH, Jose J, Schmitt L (2014) Crystal structure of the transport unit of the autotransporters adhesion involved in diffuse adherence from Escherichia coli. J Struct Biol, 187:20-29.
104. Saenger T, Braukmann A, Vordenbäumen S, Altendorfer I, Bleck E, Hochwallner H, Valenta R, Schneider M, Jose J (2014) Development of a surface display ELISA to detect anti-IgG antibodies against bovine alphaS1-Casein in human sera. J Pharm Biomed Anal, 96:144-150.
103. Bouaziz Z, Samar I, Gentili J, Gratz A, Bollacke A, Kassack M, Jose J, Herfindal L, Gausdal G, Doskeland SO, Mullié C, Sonnet P, Desgrouas C, Taudon N, Valdameri G, Di Pietro A, Baitiche M, Le Borgne M (2014) Biologically active carbazole derivatives: focus on oxazinocarbazoles and related compounds. J Enz Inhib Med Chem, 30:180-188.
102. Yoo G, Bong JH, Kim S, Jose J, Pyun JC (2014) Microarray based on autodisplayed Ro proteins for medical diagnosis of systemic lupus erythematosus (SLE). Biosens Bioelectron 57:213-218.
101. Tubeleviciute A, Teese MG, Jose J (2014) Escherichia Coli kduD encodes an oxidoreductase that converts both sugar and steroid substrates. Appl Microbiol Biotechnol, 98:5471-5485.
100. Kranen E, Detzel C, Weber T, Jose J (2014) Autodisplay for the co-expression of lipase and foldase on the surface of E. coli: washing with designer bugs. Microb Cell Fact, 3:19.
99. Szermerski M, Melesina J, Wichapong K, Löppenberg M, Jose J, Sippl W, Holl R (2014) Synthesis, biological evaluation and molecular docking studies of benzyloxyacetohydroxamic acids as LpxC inhibitors. Bioorg Med Chem, 22:1016-1028.
98. Park M, Bong, JH, Jose J, Kang, MJ, Pyun JC (2014) FACS-based immunoassay of troponin-I using E. coli cells with autodisplayed Z-domains.Anal Method; 6:1700-1708.
97. Braukmann A, Vordenbäumen S, Schneider M, Jose J (2013) Innovative ELISA-Plattform für flexible Diagnostik. M&K Kompakt „Labor und Diagnostik“, 10:22-23.
96. Vordenbäumen S, Braukmann A, Altendorfer I, Bleck E, Jose J, Schneider M (2013) Human casein alpha s1 (CSN1S1) skews in vitro differentiation of monocytes towards macrophages. BMC Immunology; 14:46.
95. Al Chab F, Fenet B, LeBorgne M, Jose J, Ettouati L, Pinaud N, Guillon J (2013) 1H and 13C NMR assignments of bioactive indeno[1,2-b]indole-10-one derivatives. Magn Reson Chem; 51:837-841.
94. Rongved P, Kirsch G, Bouaziz Z, Jose J, LeBorgne M (2013) Indenoindoles and cyclopentacarbazoles as bioactive compounds: synthesis and biological applications - A review. Eur J Med Chem; 69:465-479.
93. Jana SK, Löppenberg M, Daniliuc CG, Jose J, Holl R (2013) Development of novel LpxC inhibitors: chiral-pool synthesis of C-triazolyl glycosides. Tetrahedron, 69:9434-9442.
92. Gawarzewski I, Tschapek B, Hoeppner A, Jose J, Smits S, Schmitt L (2013) Purification, crystallization and preliminary X-ray crystallographic analysis of the transport unit of the monomeric autotransporter AIDA-I from Escherichia coli. Acta Crystallogr Sect F; F69, 1159-1162.
91. Ölgen S, Gratz A, Kurt ZK, Jose J (2013) N-substituted indole-2 and 3-carboxamide derivatives as inhibitors of human protein kinase CK2: in vitro assay and molecular modeling study. Acta Chim Slov , 60:628-635.
90. Gawarzewski I, Smits SHJ, Schmitt L, Jose J (2013) Structural comparison of the transport units of type V secretion systems. Biol Chem, 394:1385-1398.
89. Oh J, Yoo G, Chang YW, Kim HJ, Jose J, Kim E, Pyun JC, Yoo K-H (2013) A carbon nanotube metal semiconductor field effect transistor-based biosensor for detection of amyloid-beta in human serum. Biosens Bioelectron, 50:345-350.
88. Löppenberg M, Müller H, Pulina C, Oddo A, Teese MG, Jose J, Holl R (2013) Synthesis and biological evaluation of flexible and conformationally constrained LpxC inhibitors. Org Biomol Chem, 11:6056-6070. 
87. Park M, Bong JH, Yoo G, Jose J, Kang MJ, Pyun JC (2013) Optimization of a FACS based-immunoassay using E. coli autodisplaying Z-domains. BioChip J, 7(2):173-179.
86. Guillon J, Le Borgne M, Rimbault C, Moreau S, Savrimoutou S, Pinaud N, Marchivie M, Bollacke A, Pecci A, Alvarez L, Desplat V, Jose J (2013) Synthesis and biological evaluation of novel substituted pyrrolo[1,2-a]quinoxaline derivatives as inhibitors of the human protein kinase CK2. Eur J Med Chem, 65:205-222.
85. Park M, Bong JH, Yoo G, Jose J, Kang MJ, Pyun JC (2013) Flow cytometric immunoassay using E. coli with autodisplayed Z-domains. Enzyme Microb Tech, 53:181-188.
84. Yoo G, Park M, Bong JH, Jose J, Pyun JC (2013) Magnetic bead based immunoassay using E. coli cells with autodisplayed Z-domains. Enzyme Microb Tech, 53:118-122.
83. Raaf J, Guerra B, Neundorf I, Bopp B, Issinger OG, Jose J, Pietsch M, Niefind K (2013) First structure of protein kinase CK2 catalytic subunit with an effective CK2ß-competitive ligand. ACS Chem Biol, 8:901-907.
82. Perret F, Marminon C, Zeinyeh W, Nebois P, Bollacke A, Jose J, Parrot-Lopez H, Le Borgne M (2013) Preparation and characterization of CK2 inhibitor-loaded cyclodextrin nanoparticles for drug delivery. Int J Pharm, 441:491-498.
81. Detzel C, Maas R, Tubeleviciute A, Jose J (2013) Autodisplay of nitrilase from Klebsiella pneumonia and whole-cell degradation of oxynil herbicides and related compounds. Appl Microbiol Biotechnol, 97:4887-4896.
80. Lee EH, Yoo G, Jose J, Kang MJ, Song SM, Pyun, JC (2013) SPR biosensor based on immobilized E. coli cells with autodisplayed Z-domains. Biochip J, 6:221-228.
79. Jose J (2013) Ausdrucksstark. q&more, 1:12-17.
78. Hundsdörfer C, Hemmerling HJ, Hamberger J, Le Borgne M, Bednarski P, Götz C, Totzke F, Jose J (2012) Novel indeno[1,2-b]indoloquinones as inhibitors of the human protein kinase CK2 with antiproliferative activity towards a broad panel of cancer cell lines. Biochem Biophys Res Commun, 424:71-75.
77. Jose J, Maas RM, Teese MG (2012) Autodisplay of enzymes - molecular basis and perspectives.  J Biotechnol, 161:92-103.
76. Götz C, Gratz A, Kucklaender U, Jose J (2012) TF – a novel cell-permeable and selective inhibitor of human protein kinase CK2 induces apoptosis in the prostate cancer cell line LNCaP. Biochim Biophys Acta - General subjects, 1820:970-977.
75. Schumacher SD, Hannemann F, Teese MG, Bernhardt R, Jose J (2012) Autodisplay of functional CYP106A2 in Escherichia coli. J Biotechnol, 161:104-112.
74. Schumacher SD, Jose J (2012) Expression of active human P450 3A4 on the cell surface of Escherichia coli by autodisplay. FREE Access in 2014:  J Biotechnol, 161:113-120. Elsevier Biotech Article most tweeted in 2012
73. Petermann K, Vordenbäumen S, Maas R, Braukmann A, Bleck E, Saenger T, Schneider M, Jose J (2012) Autoantibodies to alphaS1-Casein are induced by breast-feeding. Plos One, 7:e32716.
72. Hundsdörfer C, Hemmerling HJ, Götz C, Totzke F, Bednarski P, Le Borgne M,  Jose J (2012) Indeno[1,2-b]indole derivatives as a novel class of potent human protein kinase CK2 inhibitors.  Bioorg Med Chem, 20:2282-2289.
71. Lee JK, Yoo G, Park M, Jose J, Kang MJ, Pyun JC (2012) Electrochemical ELISA based on Escherichia coli with autodisplayed Z-domains. Sensor Acuat B-Chem, 175:46-52.
70. Lee JK, Yoo G, Park M, Jose J, Kang MJ, Pyun JC (2011) Electrochemical ELISA based on E. coli with autodisplayed Z-domains. Procedia Engineering, 25:944-947.
69. Yoo G, Park M, Lee E-H, Jose J, Pyun JC (2011) Immobilization of E. coli with autodisplayed Z-domains to a surface-modified microplate for immunoassay. Anal Chim Acta, 707:142-147.
68. Gratz A, Kuckländer U, Bollig R, Götz C, Jose J (2011) Identification of novel CK2 inhibitors with a benzofuran scaffold by novel non-radiometric in vitro assays. Mol Cell Biochem, 356:83-90.
67. Olgen S, Kaessler A, Kilic Kurt Z, Jose J (2011) Structure-activity evaluation of N-benzyl-5-substituted indole-3-imine derivatives and their amine congeners as bovine testicular hyaluronidase (BTH) inhibitor. Lett Drug Des Discov, 8:685-690.
66. Kranen E, Steffan N, Maas RM, Li SM, Jose J (2011) Development of a whole cell biocatalyst for the efficient prenylation of indole derivatives by Autodisplay of the aromatic prenyltransferase FgaPT2, ChemCatChem, 3:1200-1207.
65. Detzel C, Maas R, Jose J (2011) Autodisplay of nitrilase from Alcaligenes faecalis in E. coli yields a whole cell biocatalyst for the synthesis of enantiomerically pure R-mandelic acid. ChemCat Chem, 3, 719-725.
64. Park M, Jose J, Pyun JC (2011) SPR biosensor by using E. coli outer membrane layer with autodisplayed Z-domains. Sensor Actuat B-Chem, 154:82-88.
63. Kucklaender U, Bollig R, Frank W, Gratz A, Jose J (2011) A novel application of DDQ as electrophile in the Nenitzescu reaction. Bioorg Med Chem, 19:2666-2674.
62. Park M, Jose J, Thömmes S, Kim J, Park MJ, Pyun JC (2011) Autodisplay of streptavidin. Enzyme Microb Tech, 48:307-311.
61. Gratz A, Jose J (2011) Focussing mutations to defined domains: protein domain library generation by overlap extension (PDLGO). Methods in Molecular Biology, Volume 279; cDNA Libraries: New Techniques and Applications (eds. Lu, Browse, Wallis), Humana Press, London, 1st Edition, ISBN: 978-1-61779-064-5, pp. 153-166.
60. Kaeßler A, Olgen S, Jose J (2011) Autodisplay of catalytically active human hyaluronidase hPH-20 and testing of enzyme inhibitors. Europ J Pharm Sci, 42: 138-147.
59. Vordenbäumen S, Petermann K, Braukmann A, Bleck E, Jose J, Schneider S (2011) Casein alpha s1 (CSN1S1) is expressed by human monocytes and upregulates the production of GM-CSF via p38 MAP kinase. J Immunol, 186: 592-601.
2010 and before  
58. Maas R, Jose J, Festel G (2010) Autodisplay Biotech: Neue Lösungen für Biokatalyse, Drug Discovery und Bioanalyse. Chemie Ingenieur Technik (CIT), 82:1520-1521. 
57. Petermann K, Vordenbäumen S, Braukmann A, Pyun JC, Bleck E, Schneider S, Jose J (2010) Autodisplay of 60 kDa Ro/SS-A and development of a surface display ELISA (SD-ELISA) for SLE patient sera screening. Anal Biochem, 407:72-78.
56. Olgen S, Kaeßler A, Kiliç-Kurt Z, Jose J (2010) Investigation of Aminomethyl Indole Derivatives as Hyaluronidase Inhibitors. Z Naturforsch C, 65:445-450.
55. Jose J, Park M, Pyun JC (2010) Highly sensitive immunoassay based on E. coli with autodisplayed Z-domain. Anal Chim Acta, 667:113-118.
54. Bouaziz Z, Issa S, Jose J, Gratz A, Götz C, Di Pietro A, Falson P, Arnaud O, Le Borgne M (2010) Targeting Casein Kinase 2 in Drug Discovery: Identification of New Chemical Entities. B Cancer 97: 68S-69S.
53. Park M, Jose J, Pyun JC (2010) Hypersensitive immunoassay by using E. coli outer membrane with autodisplayed Z-domains. Enzyme Microb Tech, 46:309-314.
52. Gratz A, Götz, C, Jose J (2010) A CE-based assay for human protein kinase CK2 activity measurement and inhibitor screening. Electrophoresis, 31:634-640.
51. Jose J, Park M, Pyun JC (2010) E. coli outer membrane with autodisplayed Z-domain as a molecular recognition layer of SPR biosensor. Biosens Bioelectron, 25:1225-1228.
50. Gratz A, Goetz C, Jose J (2010) A FRET-based microplate assay for human protein kinase CK2, a target in neoplastic diseases. J Enz Inhibit Med Chem, 25:234-239.
49. Park M, Jose J, Pyun JC (2009) E. coli outer membrane with autodisplayed Z-domain as a molecular recognition layer of SPR biosensor. Procedia Chem 1:1475-1478.
48. Jose J, Chung JW, Jeon JB, Maas RM, Nam CH, Pyun JC (2009) E. coli with autodisplayed Z-domain of protein A for signal amplification of SPR biosensensor. Biosens Bioelectron, 24: 1324-1329.
47. Betscheider D, Jose J (2009) Nile Blue A for staining Escherichia coli in flow cytometer experiments. Anal Biochem, 384:194-196.
46. Jose J (2009) Bioanalytics in medicinal chemistry: from assay development to evolutive drug design. Ann Pharm Fr, 67:399-407.
45. Schultheiss E, Weiss S, Winterer E, Maas R, Heinzle E, Jose J (2008) Esterase autodisplay: enzyme engineering and whole cell activity determination by microplates with integrated pH-sensors. Appl Environ Microbiol, 74:4782-4791.
44. Kaessler A, Nourrisson, MR, Duflos M, Jose J (2008) Indole carboxamides inhibit and indole acetamides activate bovine testes hyaluronidase by different mechanisms at distinct pH values.J Enz Inhib Med Chem, 23: 719–727.
43. Algul O, Kaessler A, Apcin Y,  Yilmaz A , Jose J (2008) Comparative studies on conventional and microwave synthesis of some benzimidazole, benzothiazole and indole derivatives and testing on inhibition of hyaluronidase. Molecules, 13:736-748.
42. Jose J, Festel G. Maas R (2008) Autodisplay Biotech GmbH – Entwicklung von maßgeschneiderten Ganzzellbiokatalysatoren und small protein drugs. Jahrbuch der Heinrich-Heine-Universität Düsseldorf 2007/2008, Hrsg. Alfons Labisch, Düsseldorf University Press, Düsseldorf, pp. 611-619.
41. Gratz A, Jose J (2008) Protein domain library generation by overlap extension (PDLGO): a tool for enzyme engineering. Anal Biochem, 378:171-176.
40. Jose J, Meyer TF (2007) The autodisplay story – from discovery to biotechnical and biomedical applications. Microbiol Mol Biol R, 71:600-619.
39. Olgen S, Kaessler A, Nobioglu D, Jose J (2007) New potent indole derivatives as hyaluronidase inhibitors, Chem Biol Drug Des, 70:547-551.
38. Kaessler A, Algül Ö, Jose J (2007) A microplate based screening of benzimidazole derivatives on hyaluronidase inhibition at pH 3.5 and pH 7.0. Lett Drug Des Discov, 4:562-569.
37. Hannemann F, Bernhardt R, Jose J (2007) Biocatalytic synthesis of 4-Pregnen-20, 21-diol-3-one, a selective inhibitor of human 5α-reductase type II. J Enz Inhib Med Chem, 22:570-576.
36. Olgan S, Götz C, Jose J (2007) Synthesis and biological evaluation of 3-(Substituted-benzylidene)-1, 3-dihydro-indolin derivatives as human protein kinase CK2 and p60c-Src tyrosine kinase inhibitors. Biol Pharm Bull, 30:715-718.
35. Jose J (2006) Autodisplay: efficient bacterial surface display of recombinant proteins. Appl Microbiol Biotechnol, 69:607-614.
34. Hussein SA, Hashim AN, Barakat HH, Jose J, Lindequist U, Nawwar MA (2006) Phenolics from extracts of Brahea armata with inhibitory effect against 5α-reductase type-II. Pharmazie, 12: 1034-1037.
33. Jose J, Betscheider D, Zangen D (2005) Bacterial Surface Display Library Screening by target enzyme labelling: Identification of New Human Cathepsin G Inhibitors. Anal Biochem, 346:258-267.
32. Jose J and Zangen D (2005) Autodisplay of the protease inhibitor aprotinin in Escherichia coli. Biochem Biophys Res Commun, 333:1218-1226.
31. Panter BU, Jose J, Hartmann RW (2005) 5α-reductase in human embryonic kidney cell line HEK293: evidence for type II enzyme expression and activity. Mol Cell Biochem, 270:201-208.
30. Bild T, Jose J, Hartmann RW (2004) Discovery of inhibitors of MCF-7 tumor cell adhesion to endothelial cells and investigation on their mode of action. Arch Pharm Pharm Med Chem, 337:687-694.
29. Jose J und von Schwichow S (2004) “Cystope tagging” for labelling and detection of recombinant protein expression. Anal Biochem, 331:267-274.
28. Jose J und von Schwichow S (2004) Autodisplay of active sorbitol dehydrogenase (SDH) yields a whole cell biocatalyst for the synthesis of rare sugars. ChemBioChem, 5:491-499.
27. Heinzle E, Weiss S, Wolfbeis O, Arain S, Klimant I, John G, Räbiger T, Müller G, Waltenberger H, Schultheiss E, Jose J (2003) Mikrotiterplatten-Reaktoren mit integrierten pH-Sensoren und Autodisplay in E. coli zur evolutiven Enzymentwicklung. Transkript, 9:59-62.
26. Jose J und Handel S (2003) Monitoring the surface display of recombinant proteins by cysteine labeling and flow cytometry. ChemBioChem, 4: 396-405.
25. Talker D, Jose J, Glieder A, Pressnig M, Stubenrauch G, Schwab H (2003) Esterase EstE from Xanthomonas vesicatoria (Xv_EstE) is an outer membrane protein capable of hydrolyzing long chain polar esters. Appl Microbiol Biotechnol, 61:479-487.
24. Jose J, Otto GW, Meyer TF (2003) The integration site of the iga gene in commensal Neisseria sp. Mol Gen Genom, 269:197-204.
23. Jose J, Betscheider D, Ray S, Lengauer T, Zangen D (2003) New inhibitors of human cathepsin G identified by surface display library screening and peptide-protein docking. Proceedings of 7th International Symposium on Pharmaceutical Sciences (ISOPS-7), (Eds.: Akin, Ahmet et al.),  Tasarim Basim, Ankara, pp. 46-49.
22. Schultheiss E, Paar C, Schwab H, Jose J (2002) Functional esterase surface display by the autotransporter pathway in Escherichia coli. J Mol Catal B: Enz, 18:89-97.
21. Jose J, Bernhardt R, Hannemann F (2002) Cellular surface display of dimeric Adx and whole cell P450-mediated steroid synthesis on E. coli. J Biotechnol, 95: 257-268.
20. Hartmann RW, Ehmer PB, Haidar S., Jose J, Hector M, Klein CDP, Seidel S, Sergejew TF, Wachall BG, Wächter GA, Zhuang Y (2002) Review: Inhibition of CYP17, a new strategy for the treatment of prostate cancer. Arch Pharm Pharm Med Chem, 335: 119-128.
19. Weiß S, John GT, Heinzle E, Schultheiss E, Jose J, Arain S, Krause, Klimant I, Waltenberger H, Maier J, Räbiger T (2001) Screening von Biokatalysatoren mit Sauerstoff- und pH – Mikrotiterplatten. BioSpectrum, Sonderband Biokatalyse: 54-60.
18. Reichert W, Michel A, Hartmann RW, Jose J (2001) Stable expression of human 5α-reductase type II in COS1 cells due to chromosomal gene integration: a novel tool for inhibitor identification. J Steroid Biochem Mol Biol, 78:275-284.
17. Jose J, Bernhardt R, Hannemann F (2001) Functional display of active bovine adrenodoxin on the surface of E. coli by chemical incorporation of the [2Fe-2S] cluster. ChemBioChem, 2:695-701.
16. Reichert W, Hartmann RW, Jose J (2001) Stable expression of the human 5α-reductase - isoenzymes type I and type II in HEK293 cells to identify dual and selective inhibitors. J Enz Inhibit, 16:47-53.
15. Kleber A, Hartmann RW, Jose J (2001) No effect of thromboxane A2 on the attachment of the tumor cell lines MDA MB 231, DU145, and U937 to the basement membrane in an in-vitro model. J Cancer Res Clin Oncol, 127:751-754.
14. Jose J, Lauter S, Stein MA (2001) Site-directed mutagenesis of cysteine to threonine in Proteus vulgaris urease active site increases enzyme activity and stability. Biotechnol Lett, 23:1263-1267.
2000 and before  
13. Hartmann RW, Hector M,  Haidar S, Ehmer PB, Reichert W, Jose J (2000) Synthesis and Evaluation of Novel Steroidal Oximes Inhibitors of P450 17 (17α-Hydroxylase/C17-20-Lyase) and 5α-Reductase Type 1 and 2. J Med Chem, 43:4266-4277.
12. Jose J, Wölk U, Lorenzen D, Wenschuh H, Meyer TF (2000) Human T cell response to meningococcal IgA 1 protease associated α-proteins. Scand J Immunol, 51:176-184.
11. Ehmer PB, Jose J, Hartmann RW (2000) Development of a simple and rapid test assay for inhibitors of human 17α-hydroxylase-C17,20-lyase by coexpression of cytochrome P450c17 and NADPH-cytochrome-P450 reductase in Escherichia coli. J Steroid Biochem Mol Biol, 75:57-63
10. Kleber A, Jose J, Hartmann RW (2000) Development of an improved in vitro model to study the adhesion of tumor cells to the basement membrane. Pharm Pharmacol Lett, 10:55-58.
9. Reichert W, Jose J, Hartmann RW (2000) 5α-Reductase in intact DU145 cells: Evidence for isozyme I and evaluation of novel inhibitors. Arch Pharm Pharm Med Chem, 333:201-204.
8. Maurer J, Jose J, Meyer TF (1999) AIDA-I-autotransporter: Characterization of the essential transport function and evidence to support structural prediction. J Bacteriol, 181:7014-7020.
7. Maurer J, Jose J, Meyer TF (1997) Autodisplay: One-component-system for efficient surface display and release of soluble recombinant proteins from Escherichia coli. J Bacteriol, 179:794-804. "Journal Highlight of the month" der American Society for Microbiology ASM
6. Mellies J, Jose J, Meyer TF (1997). The Neisseria gonorrhoeae gene aniA encodes an inducible  nitrite reductase. Mol Gen Genet, 256:525-532.
5. Jose J, Krämer J,  Klauser T, Pohlner J, Meyer TF (1996) Absence of periplasmic DsbA oxidoreductase facilitates export of cysteine-containing passenger proteins to the Escherichia coli surface via the Igaβ autotransporter pathway. Gene, 178:107-110.
4. Jose J, Jähnig F, Meyer TF (1995) Common structural features of IgA1-protease-like outer membrane protein autotransporters. Mol Microbiol 18: 380-382.
3. Jose J, Schäfer U, Kaltwasser H (1994) Threonine is present instead of cysteine at the active site of urease from Staphylococcus xylosus. Arch Microbiol, 161: 384-392.

Christians S, Jose J, Schäfer U, Kaltwasser H (1991) Purification and subunit determination of the nickel-dependent Staphylococcus xylosus urease. FEMS Microbiol Lett, 80: 271-276.

1. Jose J, Christians S, Rosenstein R, Götz F, Kaltwasser H (1991) Cloning and expression of various staphylococcal genes encoding urease in Staphylococcus carnosus. FEMS Microbiol Lett, 80: 277-282.