

University of Münster
Mail: d_kali01@uni-muenster.de
Dr. Dmitrii V. Kalinin |
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since 2018 | Group Leader at the Institute of Pharmaceutical and Medicinal Chemistry, University of Münster, Germany |
2017-2018 | Postdoc at the University of Southern Denmark (group of Prof. T. Ulven), Denmark |
2015 | Research Stay (Molecular Modelling) at the Institute of Pharmacy, Martin-Luther-Universität Halle-Wittenberg (group of Prof. W. Sippl), Germany |
2013-2017 | Ph.D. Fellow of the International “Cells in Motion” Graduate School, University of Münster (group of Prof. B. Wünsch and Prof. R. Holl), Germany Dissertation: Amino Acid- and Triazole-Based Hydroxamates Targeting Zn2+-dependent Enzymes (LpxC, MMPs, and smHDAC8): Synthesis, Biological Evaluation, Docking Studies, and PET Tracer Development, 477 pages, Münster, 2016. |
2012 | Research Associate at the School of Pharmacy, Curtin University of Technology (group of Prof. A. Dolzhenko), Australia |
2010-2012 | Organic Chemistry Assistant at the Perm State Pharmaceutical Academy and work as a Pharmacist, Russia |
2004-2009 | Study of Pharmacy, Perm State Pharmaceutical Academy, Russia |
Awards and Honors |
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2017 | “Cells-in-Motion Bridging Grant” (short-lasting Post-doc position, CiM, WWU) |
2015 | “Pilot Project Grant” (start-up financing for research project, CiM, WWU) |
2016 | Best poster prize, Symposium on Medicinal Chemistry EFMC-ISMC 2016, Manchester, UK |
2014 | Best poster prize, 7th Summer school "Medicinal Chemistry", University of Regensburg, Germany |
2013 | Ph.D. Fellowship of the “Cells in motion” Graduate School |
2013 | Endeavour Postgraduate Scholarship in Australia (declined in a favor of “CIM Fellowship”) |
2012 | Scholarship of the President of the Russian Federation for Traineeship Abroad |
2011 | Research Grant “START” (Fund for Assistance to Small Innovative Enterprises in Science and Technology) |
2010 | Research Grant “UMNIK” – the pre-seed funding program (Fund for Assistance to Small Innovative Enterprises in Science and Technology) |
2008 | Best poster and presentation prize, National Congress “Man and Medicine”, Moscow |
2008, 2009 | Scholarship of the President of the Russian Federation |
2006 | Scholarship of the Head of the City of Perm |
Topics of Research |
Blood Coagulation Synthesis of Small Molecules Targeting Thrombosis Blood Coagulation Factors and Neuroinflammation |
Our research activities lay in the field of Medicinal Chemistry and Drug Design. We are mainly focused on the development of new chemical entities aiming to address blood coagulation factors to find their application as anticoagulant agents. For this purpose, we utilize a computational approach to design new molecules followed by their synthesis and analytical characterization. Additional emphasis is placed on the drug-like characteristics of compounds, e.g. lipophilicity, solubility, stability etc. Newly synthesized potential anticoagulants are subjected to enzymatic assays and in vitro coagulation tests. This Project is supported by the Deutsche Forschungsgemeinschaft (DFG) |