Sebastian Schreiber

Ph.D. Student














Kontakt:

PharmaCampus der Universität Münster
Institut für Pharmazeutische und Medizinische Chemie
Corrensstraße 48
48149 Münster

Tel.: +49 (0)251 83-32205
Raum: A.110.107
E-Mail

 

Current Research Topic:

Characterization of interactions regulating the assembly of outer membrane proteins in Gram-negative bacteria

Teaching:

  • Praktikum 5. Semester: "Biochemische Untersuchungsmethoden einschl. klinischer Chemie"

Papers:

  • Wang TY, Latimer J, Rukundo J-L, Kogan I, Krylova S, Schreiber S, Kohlmann P, Jose J, Krylov S (2024) A Practical Approach to Quantitatively Assessing Equilibrium-Constant Accuracy from a Single Binding Isotherm. ACS Precision Chemistry, published online.
    https://doi.org/10.1021/prechem.4c00085
  • Schreiber S, Jose J (2024) Förster Resonance Energy Transfer Measurements in Living Bacteria for Interaction Studies of BamA with BamD and Inhibitor Identification. Cells, 13:1858.
    https://doi.org/10.3390/cells13221858, IF: 5.1
  • Schreiber, S, Zaayenga, A & Jose, J (2024). The assembly of the inverse autotransporter protein YeeJ is driven by its C-terminal β-strand. J Mol Biol, 436:168749.
    https://doi.org/https://doi.org/10.1016/j.jmb.2024.168749, IF: 4.7
  • Wang T, Latimer J, Rukundo JL, Kogan I, Krylova S, Schreiber S, Kohlmann P, Jose J, Krylov S (2024) Introducing Quantitative Assessment of Accuracy for the Equilibrium Constant of Affinity Complexes. ChemRxiv ​
    https://doi.org/10.26434/chemrxiv-2024-lg58f
  • Hardebeck S, Jácobo Goebbels N, Michalski C, Schreiber S, Jose J (2024) Identification of a potent PCNA-p15-interaction inhibitor by Autodisplay based Peptide Library Screening, Microb Biotechnol, 17:e14471 https://doi.org/10.1111/1751-7915.14471, IF: 5.7
  • Schreiber S, Gercke D, Lenz F, Jose J (2024) Application of an alchemical free energy method for the prediction of thermostable DuraPETase variants, Appl Microbiol Biotechnol, 108:305
    https://doi.org/10.1007/s00253-024-13144-z, IF: 5.0
  • Gesing K, Lenz F, Schreiber S, Kasimir M, Humpf HU, Jose J (2023) Surface Display and Engineering of Laccase CotA for Increased Growth of Pseudomonas putida on Lignin, ChemCatChem, 16, e202301055. https://doi.org/https://doi.org/10.1002/cctc.202301055, IF: 4.5
  • Hardebeck S, Schreiber S, Adick A, Langer K, Jose J (2023) A FRET based assay for the identification of PCNA inhibitors, Int J Mol Sci, 24:11858.
    https://doi.org/10.3390/ijms241411858, IF: 5.6
  • Elsbroek L, Amiteye D, Schreiber S, Herrmann F (2023) Molecular Imaging of Isolated Escherichia coli DH5α Peptidoglycan Sacculi Identifies the Mechanism of Action of Cell Wall-Inhibiting Antibiotics, ACS Chemical Biology, 18:848-860.
    https://doi.org/10.1021/acschembio.2c00945, IF: 4.634
  • Wojciechowski MN, Schreiber S, Jose J (2023) A Novel Flow Cytometry-Based Assay for the Identification of HCN4 CNBD Ligands, Pharmaceuticals, 16:710.
    https://doi.org/10.3390/ph16050710, IF: 5.215
  • Anderski J, Mahlert L, Sun J, Birnbaum W, Mulac D, Schreiber S, Herrmann F, Kuckling D, Langer K (2019) Light-responsive nanoparticles based on new polycarbonate polymers as innovative drug delivery systems for photosensitizers in PDT, Int J Pharm, 557:182-191.
    https://doi.org/10.1016/j.ijpharm.2018.12.040, IF: 3.061

Poster:

  • Schreiber S, Zaayenga A, Jose J (2024) The assembly of the inverse autotransporter protein YeeJ: A perspective for novel pathoblockers. DPhG Annual Meeting 2024, Münster, 23.-26.09.2024
  • Scheiber S, Gercke D, Lenz F, Jose J (2024) Design of more thermostable DuraPETase variants by alchemical free energy calculations. GCSB2024 - German Conference on Synthetic Biology 2024, Regensburg, 18.-20.09.2024
  • Schreiber S, Hardebeck S, Jose J (2024) The Stability of a proliferating cell nuclear antigen variant associated with ATLD2 is accurately predicted by non-equilibrium free energy calculations. 5th Chembion Symposium, Münster, 16.02.2024
  • Schreiber S, Hardebeck S, Jose J (2023) Non-equilibrium free energy calculations accurately predict the molecular mechanism of a disease conferring mutation in proliferating cell nuclear antigen (PCNA). ECMC2023 - 9th International Conference on Medicinal Chemistry, 01.-30.11.2023
  • Schreiber S, Ivanova D, Tozakidis IEP, Jose J (2023) The influence of the β-signal on the TAM mediated assembly of recombinant autotransporter proteins. DPhG-Jahrestagung 2023, Tübingen, 07.-10.10.2023
  • Schreiber S, Ivanova D, Tozakidis IEP, Jose J (2023) Autodisplay of fluorescent proteins sheds light on the mechanisms of bacterial autotransporter protein assembly. RICT2023 - 57th International Conference on Medicinal Chemistry, Lille, 05.-07.07.2023