International CiM-Symposium 2015

Moving Cells in Development and Disease, 13-15 September 2015


From 13 to 15 September 2015, the Cells-in-Motion Cluster of Excellence welcomed international top class researchers to the international CiM symposium „Moving Cells in Development and Disease“ in Münster.
© CiM - Peter Grewer
  • The CiM coordinators (from the left) Prof. Michael Schäfers, Prof. Lydia Sorokin und Prof. Volker Gerke as well as the organizers of the symposium Prof. Erez Raz, Prof. Christian Klämbt und Prof. Ralf Adams were happy about a successful opening.
    © CiM - Peter Grewer
  • In her keynote lecture, Prof. Ruth Lehmann (New York University School of Medicine) talked about „Lipid mediated migration of germ cells“.
    © CiM - Peter Grewer
  • Prof. Fiona Watt (King‘s College London) presented her research on „Moving epidermal cells“.
    © CiM - Peter Grewer
  • And Prof. Michael Sixt (Institute of Science and Technology Austria) gave a lecture on „Cytoskeletal responses to external load in migrating cells“.
    © CiM - Peter Grewer
  • International CiM Symposium 2015
    © CiM - Peter Grewer
  • International CiM Symposium 2015
    © CiM - Peter Grewer

At the international CiM symposium „Moving Cells in Development and Disease“, top class researchers from life and natural sciences presented their current scientific results. The list of speakers of the symposium was full of experts from the United States, from Germany, Great Britain and Switzerland. In addition, selected junior scientists from the CiM Cluster of Excellence got the opportunity to present their research.

© CiM - Peter Grewer

15 Minutes for Junior Researchers

Mandy Großgarten, a doctoral student in Chemistry, is one of eight junior researchers to speak at the International CiM Symposium.

It is not only experts from the world of biomedical research who will be speaking at the International CiM Symposium from September 13th to 15th. Eight junior researchers will also be presenting the results of their research. Mandy Großgarten, who is a doctoral student in Chemistry in the CiM research group led by Prof. Uwe Karst, is one of them.

© CiM - Peter Grewer

Something New Comes Out Every Conference

In two weeks’ time the International CiM Symposium will be bringing together scientists from a variety of disciplines. But what makes a good symposium? And what would science be without scientific symposia? The organizers of the CiM Symposium – Prof. Erez Raz, Prof. Christian Klämbt and Prof. Ralf Adams – answer these and other questions.


Sunday, 13.09.2015

Place: Castle of Münster („Schloss“), Schlossplatz 2

16:00 Registration in the foyer
Presentations in the Aula
17:00 Welcome
17:15 Ruth Lehmann (New York University School of Medicine)
Lipid mediated migration of germ cells
17:45 Fiona Watt (King‘s College London)
Moving epidermal cells
18:15 Michael Sixt (Institute of Science and Technology Austria)
Cytoskeletal responses to external load in migrating cells
19:00 Reception in the foyer

Monday, 14.09.2015

Place: Auditorium of the MPI for Molecular Biomedicine, Röntgenstraße 20

8:00 Registration

Session 1: Disease I

(Chair: Andreas Jacobs)

9:00 Steffen Massberg (Ludwig-Maximilians-Universität München)
Cell migration to vascular lesions
9:30 Erik Sahai (The Francis Crick Institute)
Heterotypic cell-cell contacts in cancer invasion
10:00 Andrew Luster (Massachusetts General Hospital)
Imaging chemokine function in disease
10:30 Coffee break

Session 2: Imaging I

(Chair: Roland Wedlich-Söldner)

11:00 Gero Miesenböck (University of Oxford)
Lighting up the brain
11:30 Mandy Großgarten (University of Münster)
Elemental bioimaging by means of LA-ICP-MS to visualize nanoparticle uptake by alveolar macrophages in vivo and in vitro
11:45 Jan Huisken (MPI of Molecular Cell Biology and Genetics)
Keeping track of cells in motion by smart and gentle microscopy
12:15 Lunch

Session 3: Imaging II

(Chair: Sebastian Rumpf)


Lydia Sorokin (University of Münster)
Imaging of matrix metalloproteinase (MMP)-2 and MMP-9 activity as a marker of neuroinflammation in mouse and man
14:05 Christian Bökel (Center for Regenerative Therapies Dresden)
Location is everything - subcellular protein distribution and signal transduction
14:35 Milos Galic (University of Münster)
Differential control of actin polymerization dynamics via nanoscale membrane curvature
14:50 Break to change session

Session 4: Intracellular Space

(Chair: Milos Galic)


Mark Peifer (The University of North Carolina)
Cytoskeletal regulation from molecules to morphogenesis
15:30 Maja Matis (University of Münster)
Microtubule mechanics in development
15:45 Ewa Paluch (University College London)
Forces during migration without focal adhesions
16:15 Sebastian Rumpf (University of Münster)
Microtubule disruption during Drosophila sensory neuron dendrite pruning
16:30 Coffee break

Session 5: Cell Migration & Communication I

(Chair: Wiebke Herzog)


Carole Parent (National Cancer Institute)
Signal relay is mediated by exosome release during Dictyostelium and neutrophil chemotaxis
17:30 Roland Wedlich-Söldner (University of Münster)
Rapid actin reorganization as a key mediator of acute calcium response in mammalian cells
17:50 Roberto Mayor (University College London)
Cell-cell interaction controls neural crest migration
18:20 Marianne Bronner (California Institute of Technology)
Molecular mechanisms underlying neural crest formation and migration

Tuesday, 15.09.2015

Place: Auditorium of the MPI for Molecular Biomedicine, Röntgenstraße 20

8:00 Registration

Session 6: Cell Migration & Communication II

(Chair: Friedemann Kiefer)


Daria Siekhaus (Institute of Science and Technology Austria)
Cytokine modulation of Drosophila macrophage tissue penetration
9:30 Sven Bogdan (University of Münster)
Shaping cells in vivo – insights from the fly
9:50 Timo Betz (University of Münster)
The role of mechanical tension in cancer cell invasion
10:05 Coffee break

Session 7: Cell Migration & Communication III

(Chair: Arndt Siekmann )

10:35 Klaus Brinkmann (University of Münster)
WHAMY is a novel WASP-like actin elongator regulating macrophage cell motility and sensory organ development in Drosophila
10:50 Robert Insall (Cancer Research UK Beatson Institute)
Self-generated chemotactic gradients - a core mechanism of cell guidance in cancer and development
11:20 Carl-Philipp Heisenberg (Institute of Science and Technology Austria)
Cell and tissue mechanics in zebrafish gastrulation
11:50 Wiebke Herzog (University of Münster)
Novel regulators of angioblast migration
12:10 Lunch

Session 8: Disease II

(Chair: Friedemann Kiefer)


Taija Mäkinen (Uppsala University)
Mechanisms of lymphvasculogenic vessel formation
14:00 Tatiana Petrova (University of Lausanne)
Biomechanical and transcriptional regulation of lymphatic vasculature
14:30 Selina Fassl (University of Münster)
Cytoskeletal interactions in autoinflammatory diseases
14:45 Coffee break

Session 9: Disease III

(Chair: Erez Raz)

15:00 Alan Burns (University College London)
The enteric nervous system: development and congenital disease
15:30 Azadeh Paksa (University of Münster)
Control of progenitor cell positioning during organogenesis
16:30 Social event: Guided walking tour through the historic city centre

Social Event: Guided Walking Tour

Speakers and attendees of the symposium are invited to join a guided walking tour through the historic city centre of Münster on Tuesday afternoon, 15th September. The tour will start at 4:30 p.m. and will take about 90 minutes. It will be delivered in English. We will finish the tour at the centrally located Dominikanerkirche, where participants will have the chance to visit the exhibition “Inner Worlds – Cells in Motion from Micro to Macro”.