Intravital Molecular Imaging (Prof. Friedemann Kiefer)
We are interested in the morphogenetic processes that shape and maintain the vascular systems, especially lymphatic vessels, during development but also in healthy and diseased adult life. In particular, we are interested by the interplay of blood and lymphatic vessels, tissue oxygenation (or the lack thereof i.e. hypoxia) and leukocytes and its relevance for organ function in various developmental and pathological settings. Our work rests on the intense use and refinement of cutting edge microscopy in combination with reporter models to visualize the individual actors of this ménage à trois within the context of the intact tissue or even dynamically in the living organism.