Publications

Accepted for publication

Dittmann M, Gonzalez Carvalho JM, Rahbar K, Schäfers M, Claesener M, Riemann B, Seifert R. Incremental diagnostic value of [18F]Tetrafluoroborate PET-CT compared to [131I]Iodine scintigraphy in recurrent differentiated thyroid cancer. Eur J Nucl Med Mol Imaging: accepted for publication.

2020

Backhaus P, Buther F, Wachsmuth L, Frohwein L, Buchholz R, Karst U, Schafers K, Hermann S, Schafers M, Faber C. Toward precise arterial input functions derived from DCE-MRI through a novel extracorporeal circulation approach in mice. Magn Reson Med 2020: epub. Abstract
Backhaus P, Roll W, Beuker C, Zinnhardt B, Seifert R, Wenning C, Eisenblatter M, Thomas C, Schmidt-Pogoda A, Strunk D, Wagner S, Faust A, Tuttelmann F, Ropke A, Jacobs AH, Stummer W, Wiendl H, Meuth SG, Schafers M, Grauer O, Minnerup J. Initial experience with [(18)F]DPA-714 TSPO-PET to image inflammation in primary angiitis of the central nervous system. Eur J Nucl Med Mol Imaging 2020Abstract
Foray C, Barca C, Backhaus P, Schelhaas S, Winkeler A, Viel T, Schafers M, Grauer O, Jacobs AH, Zinnhardt B. Multimodal Molecular Imaging of the Tumour Microenvironment. Adv Exp Med Biol 2020;1225: 71-87. Abstract
Frackowiak M, Kowar M, Sippel C, Wilhelm K, Ko Y-D, Jacobs AH. [Paraneoplastic subacute degeneration of the cerebellum in non-small cell lung cancer and positive anti-Tr3 antibodies]. Nervenarzt 2020;91: 156-160. Abstract
Kimm MA, Haas H, Stölting M, Kuhlmann M, Geyer C, Glasl S, Schäfers M, Ntziachristos V, Wildgruber M, Höltke C. Targeting Endothelin Receptors in a Murine Model of Myocardial Infarction Using a Small Molecular Fluorescent Probe. Mol Pharm 2020;17: 109-117. Abstract
Ortland I, Mendel Ott M, Kowar M, Sippel C, Jaehde U, Jacobs AH, Ko Y-D. Comparing the performance of the CARG and the CRASH score for predicting toxicity in older patients with cancer. J Geriatr Oncol 2020Abstract
Pösse S, Büther F, Mannweiler D, Hong I, Jones J, Schäfers M, Schäfers KP. Comparison of two elastic motion correction approaches for whole-body PET/CT: motion deblurring vs gate-to-gate motion correction. EJNMMI Phys 2020;7Abstract
Schwegmann K, Hohn M, Hermann S, Schafers M, Riemann B, Haufe G, Wagner S, Breyholz H-J. Optimizing the Biodistribution of Radiofluorinated Barbiturate Tracers for Matrix Metalloproteinase Imaging by Introduction of Fluorescent Dyes as Pharmacokinetic Modulators. Bioconjug Chem 2020Abstract
Vahle T, Bacher M, Rigie D, Fenchel M, Speier P, Bollenbeck J, Schafers KP, Kiefer B, Boada FE. Respiratory Motion Detection and Correction for MR Using the Pilot Tone: Applications for MR and Simultaneous PET/MR Examinations. Invest Radiol 2020;55: 153-159. Abstract
Wenning C, Vrachimis A, Pavenstadt H-J, Reuter S, Schafers M. Coronary artery calcium burden, carotid atherosclerotic plaque burden, and myocardial blood flow in patients with end-stage renal disease: A non-invasive imaging study combining PET/CT and 3D ultrasound. J Nucl Cardiol 2020Abstract
Zinnhardt B, Muther M, Roll W, Backhaus P, Jeibmann A, Foray C, Barca C, Doring C, Tavitian B, Dolle F, Weckesser M, Winkeler A, Hermann S, Wagner S, Wiendl H, Stummer W, Jacobs AH, Schafers M, Grauer OM. TSPO imaging-guided characterization of the immunosuppressive myeloid tumor microenvironment in patients with malignant glioma. Neuro Oncol 2020Abstract

2019

Freundt JK, Frommeyer G, Spieker T, Wotzel F, Grotthoff JS, Stypmann J, Hempel G, Schafers M, Jacobs AH, Eckardt L, Lange PS. Histone deacetylase inhibition by Entinostat for the prevention of electrical and structural remodeling in heart failure. BMC Pharmacol Toxicol 2019;20: 16. Abstract
Ghaffari A, Hoskin V, Turashvili G, Varma S, Mewburn J, Mullins G, Greer PA, Kiefer F, Day AG, Madarnas Y, SenGupta S, Elliott BE. Intravital imaging reveals systemic ezrin inhibition impedes cancer cell migration and lymph node metastasis in breast cancer. Breast Cancer Res 2019;21: 12. Abstract
Hunter MC, Teijeira A, Montecchi R, Russo E, Runge P, Kiefer F, Halin C. Dendritic Cells and T Cells Interact Within Murine Afferent Lymphatic Capillaries. Front. Immunol. 2019;10: 11 pp. Abstract
Junker A, Renn C, Dobelmann C, Namasivayam V, Jain S, Losenkova K, Irjala H, Duca S, Balasubramanian R, Chakraborty S, Börgel F, Zimmermann H, Yegutkin G G, Müller C E, Jacobson K A. Structure-Activity Relationship of Purine and Pyrimidine Nucleotides as Ecto-5'-Nucleotidase (CD73) Inhibitors. J Med Chem 2019;11: 3677-3695. Abstract
Kailayangiri S, Altvater B, Lesch S, Balbach S, Gottlich C, Kuhnemundt J, Mikesch J-H, Schelhaas S, Jamitzky S, Meltzer J, Farwick N, Greune L, Fluegge M, Kerl K, Lode HN, Siebert N, Muller I, Walles H, Hartmann W, Rossig C. EZH2 Inhibition in Ewing Sarcoma Upregulates GD2 Expression for Targeting with Gene-Modified T Cells. Mol Ther 2019;27: 933-946. Abstract
Kalinin DV, Agoglitta O, Van de Vyver H, Melesina J, Wagner S, Riemann B, Schafers M, Sippl W, Loffler B, Holl R. Proline-based hydroxamates targeting the zinc-dependent deacetylase LpxC: Synthesis, antibacterial properties, and docking studies. Bioorg Med Chem 2019;27: 1997-2018. Abstract
Liu Q, Junker A, Murakami K, Hu P. Automated Counting of Cancer Cells by Ensembling Deep Features. Cells 2019;8: epub. Abstract
Luxan G, Stewen J, Diaz N, Kato K, Maney SK, Aravamudhan A, Berkenfeld F, Nagelmann N, Drexler HC, Zeuschner D, Faber C, Schillers H, Hermann S, Wiseman J, Vaquerizas JM, Pitulescu ME, Adams RH. Endothelial EphB4 maintains vascular integrity and transport function in adult heart. Elife 2019;8: e45863. Abstract
Perani D, Iaccarino L, Jacobs AH. Application of advanced brain positron emission tomography-based molecular imaging for a biological framework in neurodegenerative proteinopathies. Alzheimers Dement (Amst) 2019;11: 327-332. Abstract
Perani D, Iaccarino L, Lammertsma AA, Windhorst AD, Edison P, Boellaard R, Hansson O, Nordberg A, Jacobs AH. A new perspective for advanced positron emission tomography-based molecular imaging in neurodegenerative proteinopathies. Alzheimers Dement 2019;15: 1081-1103. Abstract
Pigeon H, Peres EA, Truillet C, Jego B, Boumezbeur F, Caille F, Zinnhardt B, Jacobs AH, Le Bihan D, Winkeler A. TSPO-PET and diffusion-weighted MRI for imaging a mouse model of infiltrative human glioma. Neuro Oncol 2019;21: 755-764. Abstract
Rigie D, Vahle T, Zhao T, Czekella B, Frohwein LJ, Schafers K, Boada FE. Cardiorespiratory motion-tracking via self-refocused rosette navigators. Magn Reson Med 2019;81: 2947-2958. Abstract
Roll W, Markwardt NA, Masthoff M, Helfen A, Claussen J, Eisenblatter M, Hasenbach A, Hermann S, Karlas A, Wildgruber M, Ntziachristos V, Schafers M. Multispectral Optoacoustic Tomography of Benign and Malignant Thyroid Disorders: A Pilot Study. J Nucl Med 2019;60: 1461-1466. Abstract
Schmitzer B, Schafers KP, Wirth B. Dynamic Cell Imaging in PET with Optimal Transport Regularization. IEEE Trans Med Imaging 2019Abstract
Seifert R, Schafigh D, Hoffmeier A, Huss S, Weckesser M, Rahbar K. FDG-PET proves to be reliable in the diagnostic workup of a rare cardiac hemangioma. J Card Surg 2019Abstract
Sibille L, Seifert R, Avramovic N, Vehren T, Spottiswoode B, Zuehlsdorff S, Schafers M. (18)F-FDG PET/CT Uptake Classification in Lymphoma and Lung Cancer by Using Deep Convolutional Neural Networks. Radiology 2019: 191114. Abstract
Van Weehaeghe D, Koole M, Schmidt ME, Deman S, Jacobs AH, Souche E, Serdons K, Sunaert S, Bormans G, Vandenberghe W, Van Laere K. [(11)C]JNJ54173717, a novel P2X7 receptor radioligand as marker for neuroinflammation: human biodistribution, dosimetry, brain kinetic modelling and quantification of brain P2X7 receptors in patients with Parkinson's disease and healthy volunteers. Eur J Nucl Med Mol Imaging 2019;46: 2051-2064. Abstract
von Arnim CAF, Bartsch T, Jacobs AH, Holbrook J, Bergmann P, Zieschang T, Polidori MC, Dodel R. Diagnosis and treatment of cognitive impairment. Z Gerontol Geriatr 2019;52: 309-315. Abstract
Zinnhardt B, Belloy M, Fricke IB, Orije J, Guglielmetti C, Hermann S, Wagner S, Schafers M, Van der Linden A, Jacobs AH. Molecular Imaging of Immune Cell Dynamics During De- and Remyelination in the Cuprizone Model of Multiple Sclerosis by [(18)F]DPA-714 PET and MRI. Theranostics 2019;9: 1523-1537. Abstract

2018

Axer A, Hermann S, Kehr G, Clases D, Karst U, Fischer-Riepe L, Roth J, Fobker M, Schafers M, Gilmour R, Faust A. Harnessing the Maltodextrin Transport Mechanism for Targeted Bacterial Imaging: Structural Requirements for Improved in vivo Stability in Tracer Design. ChemMedChem 2018;13: 241-250. Abstract
Backhaus P, Noto B, Avramovic N, Grubert LS, Huss S, Bogemann M, Stegger L, Weckesser M, Schafers M, Rahbar K. Targeting PSMA by radioligands in non-prostate disease-current status and future perspectives. Eur J Nucl Med Mol Imaging 2018;45: 860-877. Abstract
Becker A, Masthoff M, Claussen J, Ford SJ, Roll W, Burg M, Barth PJ, Heindel W, Schafers M, Eisenblatter M, Wildgruber M. Multispectral optoacoustic tomography of the human breast: characterisation of healthy tissue and malignant lesions using a hybrid ultrasound-optoacoustic approach. Eur Radiol 2018;28: 602-609. Abstract
Beutel B, Song J, Konken CP, Korpos E, Schinor B, Gerwien H, Vidyadharan R, Burmeister M, Li L, Haufe G, Sorokin L. New in Vivo Compatible Matrix Metalloproteinase (MMP)-2 and MMP-9 Inhibitors. Bioconjug Chem 2018;29: 3715-3725. Abstract
Bolwin K, Czekalla B, Frohwein LJ, Büther F, Schäfers KP. Anthropomorphic thorax phantom for cardio-respiratory motion simulation in tomographic imaging. Phys Med Biol 2018;63: 035009. Abstract
Bovay E, Sabine A, Prat-Luri B, Kim S, Son K, Willrodt A-H, Olsson C, Halin C, Kiefer F, Betsholtz C, Jeon NL, Luther SA, Petrova TV. Multiple roles of lymphatic vessels in peripheral lymph node development. J Exp Med 2018;215: 2760-2777. Abstract
Büther F, Ernst I, Frohwein LJ, Pouw J, Schafers KP, Stegger L. Data-driven gating in PET: Influence of respiratory signal noise on motion resolution. Med Phys 2018;45: 3205-3213. Abstract
Butsch V, Borgel F, Galla F, Schwegmann K, Hermann S, Schafers M, Riemann B, Wunsch B, Wagner S. Design, (Radio)Synthesis, and in Vitro and in Vivo Evaluation of Highly Selective and Potent Matrix Metalloproteinase 12 (MMP-12) Inhibitors as Radiotracers for Positron Emission Tomography. J Med Chem 2018;61: 4115-4134. Abstract
Cal-Gonzalez J, Li X, Heber D, Rausch I, Moore SC, Schafers K, Hacker M, Beyer T. Partial volume correction for improved PET quantification in (18)F-NaF imaging of atherosclerotic plaques. J Nucl Cardiol 2018;25: 1742-1756. Abstract
Cal-González J, Tsoumpas C, Lassen ML, Rasul S, Koller L, Hacker M, Schäfers K, Beyer T. Impact of motion compensation and partial volume correction for[super:18]F-NaF PET/CT imaging of coronary plaque. Phys. Med. Biol. 2018;63: 015005. Abstract
Delcanale P, Galstyan A, Daniliuc CG, Grecco HE, Abbruzzetti S, Faust A, Viappiani C, Strassert CA. Oxygen-Insensitive Aggregates of Pt(II) Complexes as Phosphorescent Labels of Proteins with Luminescence Lifetime-Based Readouts. ACS Appl Mater Interfaces 2018;10: 24361-24369. Abstract
Dierkes C, Scherzinger A, Kiefer F. Three-Dimensional Visualization of the Lymphatic Vasculature. Methods Mol Biol 2018;1846: 1-18. Abstract
Duffy MJ, Planas O, Faust A, Vogl T, Hermann S, Schäfers M, Nonell S, Strassert CA. Towards optimized naphthalocyanines as sonochromes for photoacoustic imaging in vivo. Photoacoustics 2018;9: 49-61. Abstract
Frohwein LJ, Hess M, Schlicher D, Bolwin K, Büther F, Jiang X, Schäfers KP. PET attenuation correction for flexible MRI surface coils in hybrid PET/MRI using a 3D depth camera. Phys Med Biol 2018;63: 025033. Abstract
Frye M, Taddei A, Dierkes C, Martinez-Corral I, Fielden M, Ortsater H, Kazenwadel J, Calado DP, Ostergaard P, Salminen M, He L, Harvey NL, Kiefer F, Makinen T. Matrix stiffness controls lymphatic vessel formation through regulation of a GATA2-dependent transcriptional program. Nat Commun 2018;9: 1511. Abstract
Gran S, Honold L, Fehler O, Zenker S, Eligehausen S, Kuhlmann MT, Geven E, den Bosch M van, van Lent P, Spiekermann C, Hermann S, Vogl T, Schäfers M, Roth J. Imaging, myeloid precursor immortalization, and genome editing for defining mechanisms of leukocyte recruitment_in vivo_. Theranostics 2018;8: 2407-2423. Abstract
Gruner MC, Niemann S, Faust A, Strassert CA. Axially Decorated Si(IV) -phthalocyanines Bearing Mannose- or Ammonium-conjugated Siloxanes: Comparative Bacterial Labeling and Photodynamic Inactivation. Photochem Photobiol 2018;94: 890-899. Abstract
Gruner MC, Niemann S, Faust A, Strassert CA. Axially Decorated Si(IV) -phthalocyanines Bearing Mannose- or Ammonium-conjugated Siloxanes: Comparative Bacterial Labeling and Photodynamic Inactivation. Photochem Photobiol 2018;94: 890-899. Abstract
Hägerling R, Hoppe E, Dierkes C, Stehling M, Makinen T, Butz S, Vestweber D, Kiefer F. Distinct roles of VE‐cadherin for development and maintenance of specific lymph vessel beds. EMBO J 2018: e98271. Abstract
Heinemann M, Ranft A, Langer T, Jurgens H, Kreyer J, Vieth V, Schafers M, Weckesser M, Simon T, Hassenpflug W, Corbacioglu S, Bielack S, Mayer-Steinacker R, Kuhne T, van den Berg H, Gelderblom H, Bauer S, Stegger L, Dirksen U. Recurrence of Ewing sarcoma: Is detection by imaging follow-up protocol associated with survival advantage?. Pediatr Blood Cancer 2018;65: e27011. Abstract
Heming M, Gran S, Jauch S-L, Fischer-Riepe L, Russo A, Klotz L, Hermann S, Schafers M, Roth J, Barczyk-Kahlert K. Peroxisome Proliferator-Activated Receptor-γ Modulates the Response of Macrophages to Lipopolysaccharide and Glucocorticoids. Front Immunol 2018;9: 893. Abstract
Hohn M, Chang M, Meisel JE, Frost E, Schwegmann K, Hermann S, Schäfers M, Riemann B, Haufe G, Breyholz HJ, Wagner S. Synthesis and preliminary in vitro and in vivo evaluation of thiirane-based slow binding MMP inhibitors as potential radiotracers for PET imaging. Chemistry Select 2018;3: 11729-11736. Abstract
Hugenberg V, Behrends M, Wagner S, Hermann S, Schafers M, Kolb HC, Szardenings K, Walsh JC, Gomez LF, Kopka K, Haufe G. Synthesis, radiosynthesis, in vitro and first in vivo evaluation of a new matrix metalloproteinase inhibitor based on gamma-fluorinated alpha-sulfonylaminohydroxamic acid. EJNMMI Radiopharm Chem 2018;3: 10. Abstract
Konken CP, Haufe G, Brömmel K, Wünsch B, Schäfers M, Wagner S, Hugenberg V. Development of symmetric O-BODIPYs with different optical properties as building blocks for the synthesis of ligands for multimodal imaging. Dyes Pigment. 2018;158: 88-96. Abstract
Lindner O, Bauersachs J, Bengel FM, Burchert W, Vom Dahl J, Dorr R, Hacker M, Kelm M, Rassaf T, Rischpler C, Schafer W, Schafers MA, Silber S, Zimmermann R. [Policy paper nuclear cardiology - update 2018 - Current status of clinical practice]. Nuklearmedizin 2018;57: 146-152. Abstract
Lorenz L, Axnick J, Buschmann T, Henning C, Urner S, Fang S, Nurmi H, Eichhorst N, Holtmeier R, Bodis K, Hwang J-H, Mussig K, Eberhard D, Stypmann J, Kuss O, Roden M, Alitalo K, Haussinger D, Lammert E. Mechanosensing by beta1 integrin induces angiocrine signals for liver growth and survival. Nature 2018;562: 128-132. Abstract
Masthoff M, Helfen A, Claussen J, Roll W, Karlas A, Becker H, Gabriels G, Riess J, Heindel W, Schafers M, Ntziachristos V, Eisenblatter M, Gerth U, Wildgruber M. Multispectral optoacoustic tomography of systemic sclerosis. J Biophotonics 2018: e201800155. Abstract
Nensa F, Bamberg F, Rischpler C, Menezes L, Poeppel TD, la Fougere C, Beitzke D, Rasul S, Loewe C, Nikolaou K, Bucerius J, Kjaer A, Gutberlet M, Prakken NH, Vliegenthart R, Slart RHJA, Nekolla SG, Lassen ML, Pichler BJ, Schlosser T, Jacquier A, Quick HH, Schafers M, Hacker M. Hybrid cardiac imaging using PET/MRI: a joint position statement by the European Society of Cardiovascular Radiology (ESCR) and the European Association of Nuclear Medicine (EANM). Eur Radiol 2018;28: 4086-4101. Abstract
Neumann P-A, Twardy V, Becker F, Geyer C, Schwegmann K, Mohr A, Faust A, Lenz P, Rijcken E. Assessment of MMP-2/-9 expression by fluorescence endoscopy for evaluation of anastomotic healing in a murine model of anastomotic leakage. PLoS One 2018;13: e0194249. Abstract
Orlich M, Kiefer F. A qualitative comparison of ten tissue clearing techniques. Histol Histopathol 2018;33: 181-199. Abstract
Roll W, Riemann B, Schafers M, Stegger L, Vrachimis A. 177Lu-DOTATATE Therapy in Radioiodine-refractory Differentiated Thyroid Cancer: A Single Center Experience. Clin Nucl Med 2018;43: e346-e351. Abstract
Schelhaas S, Heinzmann K, Honess DJ, Smith D-M, Keen H, Heskamp S, Witney TH, Besret L, Doblas S, Griffiths JR, Aboagye EO, Jacobs AH. 3'-Deoxy-3'-[(18)F]Fluorothymidine Uptake Is Related to Thymidine Phosphorylase Expression in Various Experimental Tumor Models. Mol Imaging Biol 2018;20: 194-199. Abstract
Schelhaas S, Wachsmuth L, Hermann S, Rieder N, Heller A, Heinzmann K, Honess DJ, Smith D-M, Fricke IB, Just N, Doblas S, Sinkus R, Doring C, Schafers KP, Griffiths JR, Faber C, Schneider R, Aboagye EO, Jacobs AH. Thymidine Metabolism as a Confounding Factor for 3'-Deoxy-3'-(18)F-Fluorothymidine Uptake After Therapy in a Colorectal Cancer Model. J Nucl Med 2018;59: 1063-1069. Abstract
Seifert R, Kuhlmann MT, Eligehausen S, Kiefer F, Hermann S, Schafers M. Molecular imaging of MMP activity discriminates unstable from stable plaque phenotypes in shear-stress induced murine atherosclerosis. PLoS One 2018;13: e0204305. Abstract
Vigne J, Thackeray J, Essers J, Makowski M, Varasteh Z, Curaj A, Karlas A, Canet-Soulas E, Mulder W, Kiessling F, Schafers M, Botnar R, Wildgruber M, Hyafil F. Current and Emerging Preclinical Approaches for Imaging-Based Characterization of Atherosclerosis. Mol Imaging Biol 2018;20: 869-887. Abstract
Villa A, Klein B, Janssen B, Pedragosa J, Pepe G, Zinnhardt B, Vugts DJ, Gelosa P, Sironi L, Beaino W, Damont A, Dolle F, Jego B, Winkeler A, Ory D, Solin O, Vercouillie J, Funke U, Laner-Plamberger S, Blomster LV, Christophersen P, Vegeto E, Aigner L, Jacobs A, Planas AM, Maggi A, Windhorst AD. Identification of new molecular targets for PET imaging of the microglial anti-inflammatory activation state. Theranostics 2018;8: 5400-5418. Abstract
Voeller T, Faust A, Roth J, Schafers M, Vogl T, Hermann S. A Non-Peptidic S100A9 Specific Ligand for Optical Imaging of Phagocyte Activity In Vivo. Mol Imaging Biol 2018;20: 407-416. Abstract
Vogl T, Stratis A, Wixler V, Voller T, Thurainayagam S, Jorch SK, Zenker S, Dreiling A, Chakraborty D, Frohling M, Paruzel P, Wehmeyer C, Hermann S, Papantonopoulou O, Geyer C, Loser K, Schafers M, Ludwig S, Stoll M, Leanderson T, Schultze JL, Konig S, Pap T, Roth J. Autoinhibitory regulation of S100A8/S100A9 alarmin activity locally restricts sterile inflammation. J Clin Invest 2018;128: 1852-1866. Abstract
Wiesmann M, Timmer NM, Zinnhardt B, Reinhard D, Eligehausen S, Konigs A, Ben Jeddi H, Dederen PJ, Jacobs AH, Kiliaan AJ. Effect of a multinutrient intervention after ischemic stroke in female C57Bl/6 mice. J Neurochem 2018;144: 549-564. Abstract
Zinnhardt B, Wiesmann M, Honold L, Barca C, Schäfers M, Kiliaan A, Jacobs AH. In vivo imaging biomarkers of neuroinflammation in the development and assessment of stroke therapies - towards clinical translation. Theranostics 2018;8: 2603-2620. Abstract
Zumhagen S, Vrachimis A, Stegger L, Kies P, Wenning C, Ernsting M, Muller J, Seebohm G, Paul M, Schafers K, Stallmeyer B, Schafers M, Schulze-Bahr E. Impact of presynaptic sympathetic imbalance in long-QT syndrome by positron emission tomography. Heart 2018;104: 332-339. Abstract

2017

Abdurrachim D, Nabben M, Hoerr V, Kuhlmann MT, Bovenkamp P, Ciapaite J, Geraets IME, Coumans W, Luiken JJFP, Glatz JFC, Schafers M, Nicolay K, Faber C, Hermann S, Prompers JJ. Diabetic db/db mice do not develop heart failure upon pressure overload: a longitudinal in vivo PET, MRI, and MRS study on cardiac metabolic, structural, and functional adaptations. Cardiovasc Res 2017;113: 1148-1160. Abstract
Bolwin K, Vernekohl D, Lühder J, Czekalla B, Wessels JP, Schäfers KP. Development of a clear sub-millimeter small animal PET scanner by reducing the influence of the non-collinearity effect. J. Inst. 2017;12: C03006-C03006. Abstract
Breyholz H-J, Kopka K, Schafers M, Wagner S. Syntheses of Radioiodinated Pyrimidine-2,4,6-Triones as Potential Agents for Non-Invasive Imaging of Matrix Metalloproteinases. Pharmaceuticals (Basel) 2017;10Abstract
Büther F, Noto B, Auf der Springe K, Allkemper T, Stegger L. An artefact of PET attenuation correction caused by iron overload of the liver in clinical PET-MRI. Eur J Hybrid Imag 2017;1
Cal-Gonzalez J, Li X, Heber D, Rausch I, Moore SC, Schafers K, Hacker M, Beyer T. Partial volume correction for improved PET quantification in 18F-NaF imaging of atherosclerotic plaques. J Nucl Cardiol 2017: 1–15. Abstract
Clases D, Birka M, Sperling M, Faust A, Karst U. Isobaric dilution analysis as a calibration tool for long lived radionuclides in ICP-MS. J Trace Elem Med Biol 2017;40: 97-103. Abstract
Fricke IB, Schelhaas S, Zinnhardt B, Viel T, Hermann S, Couillard-Despres S, Jacobs AH. In vivo bioluminescence imaging of neurogenesis - the role of the blood brain barrier in an experimental model of Parkinson's disease. Eur J Neurosci 2017;45: 975-986. Abstract
Grabner A, Schramm K, Silswal N, Hendrix M, Yanucil C, Czaya B, Singh S, Wolf M, Hermann S, Stypmann J, Di Marco GS, Brand M, Wacker MJ, Faul C. FGF23/FGFR4-mediated left ventricular hypertrophy is reversible. Sci Rep 2017;7: 1993. Abstract
Hagerling R, Drees D, Scherzinger A, Dierkes C, Martin-Almedina S, Butz S, Gordon K, Schafers M, Hinrichs K, Ostergaard P, Vestweber D, Goerge T, Mansour S, Jiang X, Mortimer PS, Kiefer F. VIPAR, a quantitative approach to 3D histopathology applied to lymphatic malformations. JCI Insight 2017;2Abstract
Heinzmann K, Honess DJ, Lewis DY, Smith D-M, Cawthorne C, Keen H, Heskamp S, Schelhaas S, Witney TH, Soloviev D, Williams KJ, Jacobs AH, Aboagye EO, Griffiths JR, Brindle KM. Correction to: The relationship between endogenous thymidine concentrations and [(18)F]FLT uptake in a range of preclinical tumour models. EJNMMI Res 2017;7: 99. Abstract
Hess M, Buther F, Schafers KP. Data-Driven Methods for the Determination of Anterior-Posterior Motion in PET. IEEE Trans Med Imaging 2017;36: 422-432. Abstract
Höltke C, Faust A. Molecular imaging of integrins in oncology. Rmi 2017;Volume 10: 17-30. Abstract
Hugenberg V, Wagner S, Kopka K, Schafers M, Schuit RC, Windhorst AD, Hermann S. Radiolabeled Selective Matrix Metalloproteinase 13 (MMP-13) Inhibitors: (Radio)Syntheses and in Vitro and First in Vivo Evaluation. J Med Chem 2017;60: 307-321. Abstract
Karpanen T, Padberg Y, van de Pavert SA, Dierkes C, Morooka N, Peterson-Maduro J, van de Hoek G, Adrian M, Mochizuki N, Sekiguchi K, Kiefer F, Schulte D, Schulte-Merker S. An Evolutionarily Conserved Role for Polydom/Svep1 During Lymphatic Vessel Formation. Circ Res 2017;120: 1263-1275. Abstract
Kokornaczyk AK, Thum S, Daniliuc CG, Junker A, Wunsch B. Molecular structure of a brominated 2-benzazepinone - a crucial intermediate in the synthesis of novel chemokine CCR2 receptor antagonists. Z.Naturforsch.(B) 2017;72: 421-424. Abstract
Laukamp KR, Lindemann F, Weckesser M, Hesselmann V, Ligges S, Wölfer J, Jeibmann A, Zinnhardt B, Viel T, Schäfers M, Paulus W, Stummer W, Schober O, Jacobs AH. Multimodal Imaging of Patients With Gliomas Confirms[super:11]C-MET PET as a Complementary Marker to MRI for Noninvasive Tumor Grading and Intraindividual Follow-Up After Therapy. Molecular Imaging 2017;16: 153601211668765. Abstract
Mucke MM, Bettenworth D, Geyer C, Schwegmann K, Poremba C, Schafers M, Domagk D, Holtke C, Lenz P. Targeting Mucosal Endothelin-A-Receptor Expression by Fluorescence Endoscopy is Feasible to Detect and Characterize Colitis-Associated Cancer in Mice. Inflamm Bowel Dis 2017;24: 111-122. Abstract
Noto B, Buther F, Auf der Springe K, Avramovic N, Heindel W, Schafers M, Allkemper T, Stegger L. Impact of PET acquisition durations on image quality and lesion detectability in whole-body 68Ga-PSMA PET-MRI. EJNMMI Res 2017;7: 12. Abstract
Ortmeyer CP, Haufe G, Schäfers M, Wagner S, Schwegmann K, Hermann S, Hugenberg V. Development of 18F-fluorinated BODIPYs for multimodal imaging. J Label Compd Radiopharm 2017;60: 273. Abstract
Ortmeyer CP, Haufe G, Schwegmann K, Hermann S, Schafers M, Borgel F, Wunsch B, Wagner S, Hugenberg V. Synthesis and evaluation of a [18F]BODIPY-labeled caspase-inhibitor. Bioorg Med Chem 2017;25: 2167-2176. Abstract
Schelhaas S, Heinzmann K, Bollineni VR, Kramer GM, Liu Y, Waterton JC, Aboagye EO, Shields AF, Soloviev D, Jacobs AH. Preclinical Applications of 3'-Deoxy-3'-[18F]Fluorothymidine in Oncology - A Systematic Review. Theranostics 2017;7: 40-50. Abstract
Seifert R, Scherzinger A, Kiefer F, Hermann S, Jiang X, Schafers MA. Statistical Permutation-based Artery Mapping (SPAM): a novel approach to evaluate imaging signals in the vessel wall. BMC Med Imaging 2017;17: 36. Abstract
Sundermann B, Schroder J-B, Warnecke T, Heindel W, Schafers M, Weckesser M, Buerke B. Imaging Workup of Suspected Classical Paraneoplastic Neurological Syndromes: A Systematic Review and Retrospective Analysis of (18)F-FDG-PET-CT. Acad Radiol 2017;24: 1195-1202. Abstract
Thum S, Kokornaczyk AK, Seki T, De Maria M, Zacarias NVO, de Vries H, Weiss C, Koch M, Schepmann D, Kitamura M, Tschammer N, Heitman LH, Junker A, Wunsch B. Synthesis and biological evaluation of chemokine receptor ligands with 2-benzazepine scaffold. Eur. J. Med. Chem. 2017;135: 401-413. Abstract
Thunemann M, Schörg BF, Feil S, Lin Y, Voelkl J, Golla M, Vachaviolos A, Kohlhofer U, Quintanilla-Martinez L, Olbrich M, Ehrlichmann W, Reischl G, Griessinger CM, Langer HF, Gawaz M, Lang F, Schäfers M, Kneilling M, Pichler BJ, Feil R. Cre/lox-assisted non-invasive in vivo tracking of specific cell populations by positron emission tomography. Nat Commun 2017;8Abstract
Van de Vyver H, Bovenkamp PR, Hoerr V, Schwegmann K, Tuchscherr L, Niemann S, Kursawe L, Grosse C, Moter A, Hansen U, Neugebauer U, Kuhlmann MT, Peters G, Hermann S, Loffler B. A Novel Mouse Model of Staphylococcus aureus Vascular Graft Infection: Noninvasive Imaging of Biofilm Development in Vivo. Am J Pathol 2017;187: 268-279. Abstract
Waerzeggers Y Zinnhardt B Winkeler A Monfared P Schelhaas S Viel T Jacobs AH. Imaging in Neurooncology. In: Kiessling F., Pichler B. Small Animal Imaging 2017;Springer, Cham: 689-725. Abstract
Weis V, Konigsberger S, Amler S, Wienands J, Kiefer F. Unperturbed Immune Function despite Mutation of C-Terminal Tyrosines in Syk Previously Implicated in Signaling and Activity Regulation. Mol Cell Biol 2017;37Abstract
Wiesmann M, Zinnhardt B, Reinhardt D, Eligehausen S, Wachsmuth L, Hermann S, Dederen PJ, Hellwich M, Kuhlmann MT, Broersen LM, Heerschap A, Jacobs AH, Kiliaan AJ. A specific dietary intervention to restore brain structure and function after ischemic stroke. Theranostics 2017;7: 493-512. Abstract
Zinnhardt B, Pigeon H, Theze B, Viel T, Wachsmuth L, Fricke IB, Schelhaas S, Honold L, Schwegmann K, Wagner S, Faust A, Faber C, Kuhlmann MT, Hermann S, Schafers M, Winkeler A, Jacobs AH. Combined PET Imaging of the Inflammatory Tumor Microenvironment Identifies Margins of Unique Radiotracer Uptake. Cancer Res 2017;77: 1831-1841. Abstract

2016

Bailey DL, Pichler BJ, Guckel B, Barthel H, Beer AJ, Botnar R, Gillies R, Goh V, Gotthardt M, Hicks RJ, Lanzenberger R, la Fougere C, Lentschig M, Nekolla SG, Niederdraenk T, Nikolaou K, Nuyts J, Olego D, Riklund KA, Signore A, Schafers M, Sossi V, Suminski M, Veit-Haibach P, Umutlu L, Wissmeyer M, Beyer T. Combined PET/MRI: from Status Quo to Status Go Summary Report of the Fifth International Workshop on PET/MR Imaging; February 15-19, 2016; Tubingen, Germany. Mol Imaging Biol 2016;18: 637-650. Abstract
Bettenworth D, Mucke MM, Schwegmann K, Faust A, Poremba C, Schafers M, Domagk D, Lenz P. Endoscopy-guided orthotopic implantation of colorectal cancer cells results in metastatic colorectal cancer in mice. Clin Exp Metastasis 2016;33: 551-562. Abstract
Beutel B, Daniliuc CG, Riemann B, Schafers M, Haufe G. Fluorinated matrix metalloproteinases inhibitors-Phosphonate based potential probes for positron emission tomography. Bioorg Med Chem 2016;24: 902-909. Abstract
Buther F, Vehren T, Schafers KP, Schafers M. Impact of Data-driven Respiratory Gating in Clinical PET. Radiology 2016: 152067. Abstract
Ehlert A, Schmidt C, Wolfer J, Manthei G, Jacobs AH, Bruning R, Heindel W, Ringelstein EB, Stummer W, Pluta RM, Hesselmann V. Molsidomine for the prevention of vasospasm-related delayed ischemic neurological deficits and delayed brain infarction and the improvement of clinical outcome after subarachnoid hemorrhage: a single-center clinical observational study. J Neurosurg 2016;124: 51-58. Abstract
Erapaneedi R, Belousov VV, Schafers M, Kiefer F. A novel family of fluorescent hypoxia sensors reveal strong heterogeneity in tumor hypoxia at the cellular level. Embo J 2016;35: 102-113. Abstract
Faust A, Hermann S, Schafers M, Holtke C. Optical imaging probes and their potential contribution to radiotracer development. Nuklearmedizin 2016;55: 51-62. Abstract
Fricke IB, Viel T, Worlitzer MM, Collmann FM, Vrachimis A, Faust A, Wachsmuth L, Faber C, Dolle F, Kuhlmann MT, Schafers K, Hermann S, Schwamborn JC, Jacobs AH. 6-hydroxydopamine-induced Parkinson's disease-like degeneration generates acute microgliosis and astrogliosis in the nigrostriatal system but no bioluminescence imaging-detectable alteration in adult neurogenesis. Eur J Neurosci 2016;43: 1352-1365. Abstract
Galstyan A, Block D, Niemann S, Gruner MC, Abbruzzetti S, Oneto M, Daniliuc CG, Hermann S, Viappiani C, Schafers M, Loffler B, Strassert CA, Faust A. Labeling and Selective Inactivation of Gram-Positive Bacteria Employing Bimodal Photoprobes with Dual Readouts. Chemistry 2016;22: 5243-5252. Abstract
Galstyan A, Block D, Niemann S, Gruner MC, Abbruzzetti S, Oneto M, Daniliuc CG, Hermann S, Viappiani C, Schafers M, Loffler B, Strassert CA, Faust A. Corrigendum: Labeling and Selective Inactivation of Gram-Positive Bacteria Employing Bimodal Photoprobes with Dual Readouts. Chemistry 2016;22: 9051. Abstract
Galstyan A, Kauscher U, Block D, Ravoo BJ, Strassert CA. Silicon(IV) Phthalocyanine-Decorated Cyclodextrin Vesicles as a Self-Assembled Phototherapeutic Agent against MRSA. ACS Appl Mater Interfaces 2016;8: 12631-12637. Abstract
Galstyan A, Riehemann K, Schäfers M, Faust A. A combined experimental and computational study of the substituent effect on the photodynamic efficacy of amphiphilic Zn(ii)phthalocyanines. J. Mater. Chem. B 2016;4: 5683-5691. Abstract
Gerwien H, Hermann S, Zhang X, Korpos E, Song J, Kopka K, Faust A, Wenning C, Gross CC, Honold L, Melzer N, Opdenakker G, Wiendl H, Schafers M, Sorokin L. Imaging matrix metalloproteinase activity in multiple sclerosis as a specific marker of leukocyte penetration of the blood-brain barrier. Sci Transl Med 2016;8: 364ra152. Abstract
Geven EJW, van den Bosch MHJ, Di Ceglie I, Ascone G, Abdollahi-Roodsaz S, Sloetjes AW, Hermann S, Schafers M, van de Loo FAJ, van der Kraan PM, Koenders MI, Foell D, Roth J, Vogl T, van Lent PLEM. S100A8/A9, a potent serum and molecular imaging biomarker for synovial inflammation and joint destruction in seronegative experimental arthritis. Arthritis Res Ther 2016;18: 247. Abstract
Heinzmann K, Honess DJ, Lewis DY, Smith D-M, Cawthorne C, Keen H, Heskamp S, Schelhaas S, Witney TH, Soloviev D, Williams KJ, Jacobs AH, Aboagye EO, Griffiths JR, Brindle KM. The relationship between endogenous thymidine concentrations and [(18)F]FLT uptake in a range of preclinical tumour models. EJNMMI Res 2016;6: 63. Abstract
Hermann S, Kuhlmann MT, Starsichova A, Eligehausen S, Schafers K, Stypmann J, Tiemann K, Levkau B, Schafers M. Imaging Reveals the Connection Between Spontaneous Coronary Plaque Ruptures, Atherothrombosis, and Myocardial Infarctions in HypoE/SRBI-/- Mice. J Nucl Med 2016;57: 1420-1427. Abstract
Hugenberg V, Hermann S, Galla F, Schafers M, Wunsch B, Kolb HC, Szardenings K, Lebedev A, Walsh JC, Mocharla VP, Gangadharmath UB, Kopka K, Wagner S. Radiolabeled hydroxamate-based matrix metalloproteinase inhibitors: How chemical modifications affect pharmacokinetics and metabolic stability. Nucl Med Biol 2016;43: 424-437. Abstract
Junker A, Balasubramanian R, Ciancetta A, Uliassi E, Kiselev E, Martiriggiano C, Trujillo K, Mtchedlidze G, Birdwell L, Brown KA, Harden TK, Jacobson KA. Structure-Based Design of 3-(4-Aryl-1H-1,2,3-triazol-1-yl)-Biphenyl Derivatives as P2Y(14) Receptor Antagonists. J. Med. Chem. 2016;59: 6149-6168. Abstract
Kailayangiri S, Altvater B, Spurny C, Jamitzky S, Schelhaas S, Jacobs AH, Wiek C, Roellecke K, Hanenberg H, Hartmann W, Wiendl H, Pankratz S, Meltzer J, Farwick N, Greune L, Fluegge M, Rossig C. Targeting Ewing sarcoma with activated and GD2-specific chimeric antigen receptor-engineered human NK cells induces upregulation of immune-inhibitory HLA-G. OncoImmunology 2016: e1250050. Abstract
Kalinin DV, Wagner S, Riemann B, Hermann S, Schmidt F, Becker-Pauly C, Rose-John S, Schafers M, Holl R. Novel Potent Proline-Based Metalloproteinase Inhibitors: Design, (Radio)Synthesis, and First in Vivo Evaluation as Radiotracers for Positron Emission Tomography. J Med Chem 2016;59: 9541-9559. Abstract
Keul P, van Borren MMGJ, Ghanem A, Muller FU, Baartscheer A, Verkerk AO, Stumpel F, Schulte JS, Hamdani N, Linke WA, van Loenen P, Matus M, Schmitz W, Stypmann J, Tiemann K, Ravesloot J-H, Alewijnse AE, Hermann S, Spijkers LJA, Hiller K-H, Herr D, Heusch G, Schafers M, Peters SLM, Chun J, Levkau B. Sphingosine-1-Phosphate Receptor 1 Regulates Cardiac Function by Modulating Ca2+ Sensitivity and Na+/H+ Exchange and Mediates Protection by Ischemic Preconditioning. J Am Heart Assoc 2016;5: e003393. Abstract
Noto B, Vrachimis A, Schafers M, Stegger L, Rahbar K. Subacute Stroke Mimicking Cerebral Metastasis in 68Ga-PSMA-HBED-CC PET/CT. Clin Nucl Med 2016;41: e449-51. Abstract
O'Halloran PJ, Viel T, Murray DW, Wachsmuth L, Schwegmann K, Wagner S, Kopka K, Jarzabek MA, Dicker P, Hermann S, Faber C, Klasen T, Schafers M, O'Brien D, Prehn JHM, Jacobs AH, Byrne AT. Mechanistic interrogation of combination bevacizumab/dual PI3K/mTOR inhibitor response in glioblastoma implementing novel MR and PET imaging biomarkers. Eur J Nucl Med Mol Imaging 2016;43: 1673-1683. Abstract
Rahbar K, Weckesser M, Huss S, Semjonow A, Breyholz H-J, Schrader AJ, Schafers M, Bogemann M. Correlation of Intraprostatic Tumor Extent with 68Ga-PSMA Distribution in Patients with Prostate Cancer. J Nucl Med 2016;57: 563-567. Abstract
Reinartz G, Haverkamp U, Wullenkord R, Lehrich P, Kriz J, Buther F, Schafers K, Schafers M, Eich HT. 4D-Listmode-PET-CT and 4D-CT for optimizing PTV margins in gastric lymphoma : Determination of intra- and interfractional gastric motion. Strahlenther Onkol 2016;192: 322-332. Abstract
Schelhaas S, Held A, Baumer N, Viel T, Hermann S, Muller-Tidow C, Jacobs AH. Preclinical Evidence That 3'-Deoxy-3'-[18F]Fluorothymidine PET Can Visualize Recovery of Hematopoiesis after Gemcitabine Chemotherapy. Cancer Res 2016;76: 7089-7095. Abstract
Schelhaas S, Held A, Wachsmuth L, Hermann S, Honess DJ, Heinzmann K, Smith D-M, Griffiths JR, Faber C, Jacobs AH. Gemcitabine Mechanism of Action Confounds Early Assessment of Treatment Response by 3'-Deoxy-3'-[18F]Fluorothymidine in Preclinical Models of Lung Cancer. Cancer Res 2016;76: 7096-7105. Abstract
Schwegmann K, Bettenworth D, Hermann S, Faust A, Poremba C, Foell D, Schafers M, Domagk D, Lenz P. Detection of Early Murine Colorectal Cancer by MMP-2/-9-Guided Fluorescence Endoscopy. Inflamm Bowel Dis 2016;22: 82-91. Abstract
Vahle A-K, Hermann S, Schafers M, Wildner M, Kerem A, Ozturk E, Jure-Kunkel M, Franklin C, Lang S, Brandau S. Multimodal imaging analysis of an orthotopic head and neck cancer mouse model and application of anti-CD137 tumor immune therapy. Head Neck 2016;38: 542-549. Abstract
Vrachimis A, Burg MC, Wenning C, Allkemper T, Weckesser M, Schafers M, Stegger L. [(18)F]FDG PET/CT outperforms [(18)F]FDG PET/MRI in differentiated thyroid cancer. Eur J Nucl Med Mol Imaging 2016;43: 212-220. Abstract
Vrachimis A, Honold L, Faust A, Hermann S, Schafers M. New molecular probes of vascular inflammation. Q J Nucl Med Mol Imaging 2016;60: 194-204. Abstract
Vrachimis A, Stegger L, Wenning C, Noto B, Burg MC, Konnert JR, Allkemper T, Heindel W, Riemann B, Schafers M, Weckesser M. [(68)Ga]DOTATATE PET/MRI and [(18)F]FDG PET/CT are complementary and superior to diffusion-weighted MR imaging for radioactive-iodine-refractory differentiated thyroid cancer. Eur J Nucl Med Mol Imaging 2016;43: 1765-1772. Abstract
Vrachimis A, Weckesser M, Schafers M, Stegger L. Imaging of differentiated thyroid carcinoma: (124)I-PET/MRI may not be superior to (124)I-PET/CT. Eur J Nucl Med Mol Imaging 2016;43: 1183-1184. Abstract

2015

Ahmadzadehfar H, Rahbar K, Kurpig S, Bogemann M, Claesener M, Eppard E, Gartner F, Rogenhofer S, Schafers M, Essler M. Early side effects and first results of radioligand therapy with (177)Lu-DKFZ-617 PSMA of castrate-resistant metastatic prostate cancer: a two-centre study. EJNMMI Res 2015;5: 114. Abstract
Bailey DL, Pichler BJ, Guckel B, Barthel H, Beer AJ, Bremerich J, Czernin J, Drzezga A, Franzius C, Goh V, Hartenbach M, Iida H, Kjaer A, la Fougere C, Ladefoged CN, Law I, Nikolaou K, Quick HH, Sabri O, Schafer J, Schafers M, Wehrl HF, Beyer T. Combined PET/MRI: Multi-modality Multi-parametric Imaging Is Here: Summary Report of the 4th International Workshop on PET/MR Imaging; February 23-27, 2015, Tubingen, Germany. Mol Imaging Biol 2015;17: 595-608. Abstract
Baumer S, Baumer N, Appel N, Terheyden L, Fremerey J, Schelhaas S, Wardelmann E, Buchholz F, Berdel WE, Muller-Tidow C. Antibody-Mediated Delivery of Anti-KRAS-siRNA In Vivo Overcomes Therapy Resistance in Colon Cancer. Clin Cancer Res 2015;21: 1383-1394. Abstract
Behrends M, Wagner S, Kopka K, Schober O, Schafers M, Kumbhar S, Waller M, Haufe G. New matrix metalloproteinase inhibitors based on gamma-fluorinated alpha-aminocarboxylic and alpha-aminohydroxamic acids. Bioorg Med Chem 2015;23: 3809-3818. Abstract
Bovenkamp PR, Brix T, Lindemann F, Holtmeier R, Abdurrachim D, Kuhlmann MT, Strijkers GJ, Stypmann J, Hinrichs KH, Hoerr V. Velocity mapping of the aortic flow at 94 T in healthy mice and mice with induced heart failure using time-resolved three-dimensional phase-contrast MRI (4D PC MRI). Magma 2015;28: 315-327. Abstract
Bulk E, Ay A-S, Hammadi M, Ouadid-Ahidouch H, Schelhaas S, Hascher A, Rohde C, Thoennissen NH, Wiewrodt R, Schmidt E, Marra A, Hillejan L, Jacobs AH, Klein H-U, Dugas M, Berdel WE, Muller-Tidow C, Schwab A. Epigenetic dysregulation of KCa 31 channels induces poor prognosis in lung cancer. Int J Cancer 2015;137: 1306-1317. Abstract
Ersepke T, Buther F, Hess M, Schafers KP. A contactless approach for respiratory gating in PET using continuous-wave radar. Med Phys 2015;42: 4911. Abstract
Fahrlander E, Schelhaas S, Jacobs AH, Langer K. PEGylated human serum albumin (HSA) nanoparticles: preparation, characterization and quantification of the PEGylation extent. Nanotechnology 2015;26: 145103. Abstract
Faust A, Voller T, Busch F, Schafers M, Roth J, Hermann S, Vogl T. Development and evaluation of a non-peptidic ligand for the molecular imaging of inflammatory processes using S100A9 (MRP14) as a novel target. Chem Commun (Camb) 2015;51: 15637-15640. Abstract
Frohwein LJ, Hoerr V, Faber C, Schäfers KP. Correction of MRI-induced geometric distortions in whole-body small animal PET-MRI. Med. Phys. 2015;42: 3848-3858. Abstract
Fustero S, Simon-Fuentes A, Barrio P, Haufe G. Olefin metathesis reactions with fluorinated substrates, catalysts, and solvents. Chem Rev 2015;115: 871-930. Abstract
Heß M, Büther F, Gigengack F, Dawood M, Schäfers KP. A dual-Kinect approach to determine torso surface motion for respiratory motion correction in PET. Med. Phys. 2015;42: 2276-2286. Abstract
Junker A, Kokornaczyk AK, Zweemer AJM, Frehland B, Schepmann D, Yamaguchi J, Itami K, Faust A, Hermann S, Wagner S, Schafers M, Koch M, Weiss C, Heitman LH, Kopka K, Wunsch B. Synthesis, binding affinity and structure-activity relationships of novel, selective and dual targeting CCR2 and CCR5 receptor antagonists. Org Biomol Chem 2015;13: 2407-2422. Abstract
Limpachayaporn P, Schafers M, Haufe G. Isatin sulfonamides: potent caspases-3 and -7 inhibitors, and promising PET and SPECT radiotracers for apoptosis imaging. Future Med Chem 2015;7: 1173-1196. Abstract
Maier TM, Schober O, Gerss J, Gorlich D, Wenning C, Schaefers M, Riemann B, Vrachimis A. Differentiated thyroid cancer patients more than 60 years old paradoxically show an increased life expectancy. J Nucl Med 2015;56: 190-195. Abstract
Pulli B, Bure L, Wojtkiewicz GR, Iwamoto Y, Ali M, Li D, Schob S, Hsieh KL-C, Jacobs AH, Chen JW. Multiple sclerosis: myeloperoxidase immunoradiology improves detection of acute and chronic disease in experimental model. Radiology 2015;275: 480-489. Abstract
Reilmann R, Lippross V, Holzner E, Gigengack F, Bohlen S, Kugel H, Deppe M, Osada N, Lucke M, Riess O, Nguyen HP, Von Horsten S, Schafers K, Schafers M, Jacobs AH, Hermann S. FDG muPET Fails to Detect a Disease-Specific Phenotype in Rats Transgenic for Huntington's Disease - A 15 Months Follow-up Study. J Huntingtons Dis 2015;4: 37-47. Abstract
Santschi N, Wagner S, Daniliuc C, Hermann S, Schafers M, Gilmour R. Synthesis of 2-[(18) F]Fluoro-2-deoxyisosorbide 5-mononitrate and Assessment of Its in vivo Biodistribution as Determined by Dynamic Positron Emission Tomography (PET). ChemMedChem 2015;10: 1724-1732. Abstract
Schilson SS, Keul P, Shaikh RS, Schafers M, Levkau B, Haufe G. Synthesis of new ligands for targeting the S1P1 receptor. Bioorg Med Chem 2015;23: 1011-1026. Abstract
Shaikh RS, Keul P, Schäfers M, Levkau B, Haufe G. New fluorinated agonists for targeting the sphingosin-1-phosphate receptor 1 (S1P1). Bioorganic & Medicinal Chemistry Letters 2015;25: 5048-5051. Abstract
Shaikh RS, Schilson SS, Wagner S, Hermann S, Keul P, Levkau B, Schafers M, Haufe G. Synthesis and evaluation of fluorinated fingolimod (FTY720) analogues for sphingosine-1-phosphate receptor molecular imaging by positron emission tomography. J Med Chem 2015;58: 3471-3484. Abstract
Song J, Wu C, Korpos E, Zhang X, Agrawal SM, Wang Y, Faber C, Schafers M, Korner H, Opdenakker G, Hallmann R, Sorokin L. Focal MMP-2 and MMP-9 Activity at the Blood-Brain Barrier Promotes Chemokine-Induced Leukocyte Migration. Cell Rep 2015;10: 1040-1054. Abstract
Tenbrinck D, Jiang X. Image segmentation with arbitrary noise models by solving minimal surface problems. Pattern Recognition 2015;48: 3293-3309. Abstract
Waldmann CM, Hermann S, Faust A, Riemann B, Schober O, Schafers M, Haufe G, Kopka K. Novel fluorine-18 labeled 5-(1-pyrrolidinylsulfonyl)-7-azaisatin derivatives as potential PET tracers for in vivo imaging of activated caspases in apoptosis. Bioorg Med Chem 2015;23: 5734-5739. Abstract
Wenning C, Vrachimis A, Dell Aquila A, Penning A, Stypmann J, Schafers M. Inhomogeneous myocardial stress perfusion in SPECT studies predicts future allograft dysfunction in heart transplant recipients. EJNMMI Res 2015;5: 51. Abstract
Zinnhardt B, Viel T, Wachsmuth L, Vrachimis A, Wagner S, Breyholz H-J, Faust A, Hermann S, Kopka K, Faber C, Dolle F, Pappata S, Planas AM, Tavitian B, Schafers M, Sorokin LM, Kuhlmann MT, Jacobs AH. Multimodal imaging reveals temporal and spatial microglia and matrix metalloproteinase activity after experimental stroke. J Cereb Blood Flow Metab 2015;35: 1711-1721. Abstract

2014

Alsibai W, Hahnenkamp A, Eisenblatter M, Riemann B, Schafers M, Bremer C, Haufe G, Holtke C. Fluorescent Non-peptidic RGD Mimetics with High Selectivity for alphaVbeta3 vs alphaIIbbeta3 Integrin Receptor: Novel Probes for in Vivo Optical Imaging. J Med Chem 2014;57: 9971-9982. Abstract
Biesemann N, Mendler L, Wietelmann A, Hermann S, Schafers M, Kruger M, Boettger T, Borchardt T, Braun T. Myostatin regulates energy homeostasis in the heart and prevents heart failure. Circ Res 2014;115: 296-310. Abstract
Fieseler M, Gigengack F, Jiang X, Schafers KP. Motion correction of whole-body PET data with a joint PET-MRI registration functional. Biomed Eng Online 2014;13 Suppl 1: S2. Abstract
Jansen D, Zerbi V, Janssen CIF, van Rooij D, Zinnhardt B, Dederen PJ, Wright AJ, Broersen LM, Lutjohann D, Heerschap A, Kiliaan AJ. Impact of a multi-nutrient diet on cognition, brain metabolism, hemodynamics, and plasticity in apoE4 carrier and apoE knockout mice. Brain Struct Funct 2014;219: 1841-1868. Abstract
Junker A, Kokornaczyk AK, Strunz AK, Wünsch B. Selective and Dual Targeting of CCR2 and CCR5 Receptors: A Current Overview. Chemokines 2014: 1-55. Abstract
Junker A, Schepmann D, Yamaguchi J, Itami K, Faust A, Kopka K, Wagner S, Wünsch B. Diverse modifications of the 4-methylphenyl moiety of TAK-779 by late-stage Suzuki-Miyaura cross-coupling. Org Biomol Chem 2014;12: 177-186. Abstract
Kesner AL, Schleyer PJ, Buther F, Walter MA, Schafers KP, Koo PJ. On transcending the impasse of respiratory motion correction applications in routine clinical imaging - a consideration of a fully automated data driven motion control framework. EJNMMI Phys 2014;1: 8. Abstract
Kowar M, Frackowiak M, Friedrich C, Wilhelm K, Walger P, Jacobs AH. [Sensory aphasia during therapy with metronidazole--an important differential diagnosis of acute cerebral ischemia]. Dtsch Med Wochenschr 2014;139: 2341-2343. Abstract
Lamare F, Le Maitre A, Dawood M, Schafers KP, Fernandez P, Rimoldi OE, Visvikis D. Evaluation of respiratory and cardiac motion correction schemes in dual gated PET/CT cardiac imaging. Med Phys 2014;41: 072504. Abstract
Lenz P, Meister T, Manno M, Pennazio M, Conigliaro R, Lebkücher S, Ullerich H, Schmedt A, Floer M, Beyna T, Lenze F, Domagk D. CO2 insufflation during single-balloon enteroscopy: a multicenter randomized controlled trial. Endoscopy 2014: 53-58. Abstract
Limpachayaporn P, Wagner S, Kopka K, Schober O, Schafers M, Haufe G. Synthesis of 7-halogenated isatin sulfonamides: nonradioactive counterparts of caspase-3/-7 inhibitor-based potential radiopharmaceuticals for molecular imaging of apoptosis. J Med Chem 2014;57: 9383-9395. Abstract
Nowosielski M, DiFranco MD, Putzer D, Seiz M, Recheis W, Jacobs AH, Stockhammer G, Hutterer M. An intra-individual comparison of MRI, [18F]-FET and [18F]-FLT PET in patients with high-grade gliomas. PLoS One 2014;9: e95830. Abstract
Paul M, Kies P, Schafers M, Schulze-Bahr E. Cardiac sympathetic innervation in a patient with catecholaminergic polymorphic ventricular tachycardia. Heart Rhythm 2014;11: 1490-1491. Abstract
Pawelski H, Schnockel U, Kentrup D, Grabner A, Schafers M, Reuter S. SPECT- and PET-Based Approaches for Noninvasive Diagnosis of Acute Renal Allograft Rejection. Biomed Res Int 2014;2014: 874785. Abstract
Persigehl T, Ring J, Bremer C, Heindel W, Holtmeier R, Stypmann J, Claesener M, Hermann S, Schafers M, Zerbst C, Schliemann C, Mesters RM, Berdel WE, Schwoppe C. Non-invasive monitoring of tumor-vessel infarction by retargeted truncated tissue factor tTF-NGR using multi-modal imaging. Angiogenesis 2014;17: 235-246. Abstract
Prasad VP, Wagner S, Keul P, Hermann S, Levkau B, Schafers M, Haufe G. Synthesis of fluorinated analogues of sphingosine-1-phosphate antagonists as potential radiotracers for molecular imaging using positron emission tomography. Bioorg Med Chem 2014;22: 5168-5181. Abstract
Ring J, Hoerr V, Tuchscherr L, Kuhlmann MT, Loffler B, Faber C. MRI Visualization of Staphyloccocus aureus-Induced Infective Endocarditis in Mice. PLoS One 2014;9: e107179. Abstract
Schäfers KP, Bolwin K, Büther F, Hermann S, Jacobs AH, Kösters T, Kuhlmann M, Schäfers M, Viel T. High-Resolution Small Animal Imaging. In: Comprehensive Biomedical Physics 2014;Elsevier, Oxford: 181-211. Abstract
Schelhaas S, Wachsmuth L, Viel T, Honess DJ, Heinzmann K, Smith D-M, Hermann S, Wagner S, Kuhlmann MT, Muller-Tidow C, Kopka K, Schober O, Schafers M, Schneider R, Aboagye EO, Griffiths J, Faber C, Jacobs AH. Variability of Proliferation and Diffusion in Different Lung Cancer Models as Measured by 3'-Deoxy-3'-18F-Fluorothymidine PET and Diffusion-Weighted MR Imaging. J Nucl Med 2014;55: 983-988. Abstract
Tucci S, Flogel U, Hermann S, Sturm M, Schafers M, Spiekerkoetter U. Development and pathomechanisms of cardiomyopathy in very long-chain acyl-CoA dehydrogenase deficient (VLCAD(-/-)) mice. Biochim Biophys Acta 2014;1842: 677-685. Abstract
Vahle A-K, Domikowsky B, Schwöppe C, Krähling H, Mally S, Schäfers M, Hermann S, Shahin V, Haier J, Schwab A, Stock C. Extracellular matrix composition and interstitial pH modulate NHE1-mediated melanoma cell motility. Int J Oncol 2014;44: 78-90. Abstract
van Duijnhoven SMJ, Robillard MS, Hermann S, Kuhlmann MT, Schafers M, Nicolay K, Grull H. Imaging of MMP activity in postischemic cardiac remodeling using radiolabeled MMP-2/9 activatable peptide probes. Mol Pharm 2014;11: 1415-1423. Abstract
Vogl T, Eisenblatter M, Voller T, Zenker S, Hermann S, van Lent P, Faust A, Geyer C, Petersen B, Roebrock K, Schafers M, Bremer C, Roth J. Alarmin S100A8/S100A9 as a biomarker for molecular imaging of local inflammatory activity. Nat Commun 2014;5: 4593. Abstract
Wenning C, Kloth C, Kuhlmann MT, Jacobs AH, Schober O, Hermann S, Schafers MA. Serial F-18-FDG PET/CT distinguishes inflamed from stable plaque phenotypes in shear-stress induced murine atherosclerosis. Atherosclerosis 2014;234: 276-282. Abstract

2013

Awde AR, Boisgard R, Theze B, Dubois A, Zheng J, Dolle F, Jacobs AH, Tavitian B, Winkeler A. The translocator protein radioligand 18F-DPA-714 monitors antitumor effect of erufosine in a rat 9L intracranial glioma model. J Nucl Med 2013;54: 2125-2131. Abstract
Bettenworth D, Reuter S, Hermann S, Weckesser M, Kerstiens L, Stratis A, Nowacki TM, Ross M, Lenze F, Edemir B, Maaser C, Pap T, Koschmieder S, Heidemann J, Schäfers M, Lugering A. Translational 18F-FDG PET/CT Imaging to Monitor Lesion Activity in Intestinal Inflammation. J Nucl Med 2013;54: 748-755. Abstract
Brune C, Burger M, Sawatzky A, Kösters T, Wübbeling F. Forward-backward EM-TV methods for Inverse Problems with Poisson noise. In: Burger M, Osher S. Level-Set and PDE-based Reconstruction Methods 2013;Springer: 71-142. Abstract
Buther F, Ernst I, Hamill J, Eich HT, Schober O, Schafers M, Schafers KP. External radioactive markers for PET data-driven respiratory gating in positron emission tomography. Eur J Nucl Med Mol Imaging 2013;40: 602-614. Abstract
Corroyer-Dulmont A, Peres EA, Petit E, Guillamo J-S, Varoqueaux N, Roussel S, Toutain J, Divoux D, Mackenzie ET, Delamare J, Ibazizene M, Lecocq M, Jacobs AH, Barre L, Bernaudin M, Valable S. Detection of glioblastoma response to temozolomide combined with bevacizumab based on muMRI and muPET imaging reveals [18F]-fluoro-L-thymidine as an early and robust predictive marker for treatment efficacy. Neuro Oncol 2013;15: 41-56. Abstract
Dawood M, Gigengack F, Jiang X, Schäfers KP. A mass conservation-based optical flow method for cardiac motion correction in 3D-PET. Med Phys 2013;40: 012505. Abstract
Diepenbrock S, Hermann S, Schäfers M, Kuhlmann M, Hinrichs K. Comparative Visualization of Tracer Uptake in In Vivo Small Animal PET/CT Imaging of the Carotid Arteries. Comput Graph Forum 2013;32: 241-250. Abstract
Fieseler M, Kugel H, Gigengack F, Kösters T, Büther F, Quick HH, Faber C, Jiang X, Schäfers KP. A dynamic thorax phantom for the assessment of cardiac and respiratory motion correction in PET/MRI: A preliminary evaluation. Nucl Instrum Methods Phys Res A 2013;702: 59-63. Abstract
Gigengack F, Ruthotto L, Jiang X, Modersitzki J, Burger M, Hermann S, Schäfers KP. Atlas-Based Whole-Body PET-CT Segmentation using a Passive Contour Distance. Lect Notes Comput Sc 2013;7766: 82-92. Abstract
Gottschlag H, Kösters T, Vernekohl D, Reygers K, Schäfers KP, Wübbeling F, Wessels JP. Towards Quantitative Image Reconstruction Using Monte-Carlo Simulations in Multi-Wire Proportional Chamber-Based Small Animal PET. IEEE Trans Nucl Sci 2013;60: 3343-3354. Abstract
Grabner A, Kentrup D, Edemir B, Sirin Y, Pavenstadt H, Schlatter E, Schober O, Schafers M, Schnockel U, Reuter S. PET with 18F-FDG-labeled T lymphocytes for diagnosis of acute rat renal allograft rejection. J Nucl Med 2013;54: 1147-1153. Abstract
Grabner A, Kentrup D, Schnockel U, Gabriels G, Schroter R, Pavenstadt H, Schober O, Schlatter E, Schafers M, Reuter S. Non-invasive imaging of acute allograft rejection after rat renal transplantation using 18F-FDG PET. J Vis Exp 2013: e4240. Abstract
Hahnenkamp A, Schäfers M, Bremer C, Höltke C. Design and Synthesis of Small-Molecule Fluorescent Photoprobes Targeted to Aminopeptdase N (APN/CD13) for Optical Imaging of Angiogenesis. Bioconjug Chem 2013;24: 1027-1038. Abstract
Hoerr V, Nagelmann N, Nauerth A, Kuhlmann MT, Stypmann J, Faber C. Cardiac-respiratory self-gated cine ultra-short echo time (UTE) cardiovascular magnetic resonance for assessment of functional cardiac parameters at high magnetic fields. J Cardiovasc Magn Reson 2013;15: 59. Abstract
Hugenberg V, Riemann B, Hermann S, Schober O, Schafers M, Szardenings K, Lebedev A, Gangadharmath U, Kolb H, Walsh J, Zhang W, Kopka K, Wagner S. Inverse 1,2,3-triazole-1-yl-ethyl substituted hydroxamates as highly potent matrix metalloproteinase inhibitors: (radio)synthesis, in vitro and first in vivo evaluation. J Med Chem 2013;56: 6858-6870. Abstract
Hutterer M, Nowosielski M, Putzer D, Fougere C la, Virgolini IJ, Jacobs AH, Stockhammer G. Response to "reply to [18F]-fluoro-ethyl-L-tyrosine PET: a valuable diagnostic tool in neuro-oncology, but not all that glitters is glioma" by Hutterer et al. Neuro Oncol 2013;15: 814-815. Abstract
Hutterer M, Nowosielski M, Putzer D, Jansen NL, Seiz M, Schocke M, McCoy M, Gobel G, la Fougere C, Virgolini IJ, Trinka E, Jacobs AH, Stockhammer G. [18F]-fluoro-ethyl-L-tyrosine PET: a valuable diagnostic tool in neuro-oncology, but not all that glitters is glioma. Neuro Oncol 2013;15: 341-351. Abstract
Jiang X, Dawood M, Gigengack F, Risse B, Schmid S, Tenbrinck D, Schäfers K. Biomedical imaging: A computer vision perspective. Lect Notes Comput Sc 2013;8047: 1-19. Abstract
Jiang X, Tenbrinck D. Region based contour detection by dynamic programming. Lect Notes Comput Sc 2013;8048: 152-159. Abstract
Lenz P, Bettenworth D, Krausewitz P, Brückner M, Ketelhut S, von Bally G, Domagk D, Kemper B. Digital holographic microscopy quantifies the degree of inflammation in experimental colitis. Integr Biol (Camb). 2013;5: 624-630. Abstract
Lenz P, Roggel M, Domagk D. Double- vs single-balloon enteroscopy: single center experience with emphasis on procedural performance. Int J Colorectal Dis 2013;28: 1239-1246. Abstract
Limpachayaporn P, Riemann B, Kopka K, Schober O, Schäfers M, Haufe G. Influence of 4- or 5-substituents on the pyrrolidine ring of 5-[1-(2-methoxymethylpyrrolidinyl)sulfonyl]isatin derivatives on their inhibitory activities towards caspases-3 and -7. Eur J Med Chem 2013;64C: 562-578. Abstract
Limpachayaporn P, Schäfers M, Schober O, Kopka K, Haufe G. Synthesis of new fluorinated, 2-substituted 5-pyrrolidinylsulfonyl isatin derivatives as caspase-3 and caspase-7 inhibitors: Nonradioactive counterparts of putative PET-compatible apoptosis imaging agents. Bioorg Med Chem 2013;21: 2025-2036. Abstract
Limpachayaporn P, Wagner S, Kopka K, Hermann S, Schäfers M, Haufe G. Synthesis, 18F-radiolabeling, and in vivo biodistribution studies of N-fluorohydroxybutyl isatin sulfonamides using positron emission tomography. J Med Chem 2013;56: 4509-4520. Abstract
Lindemann F, Laukamp K, Jacobs AH, Hinrichs K. Interactive Comparative Visualization of Multimodal Brain Tumor Segmentation Data. VMV13 2013: 105-112. Abstract
Lindner O, Burchert W, Hacker M, Schaefer W, Schmidt M, Schober O, Schwaiger M, vom Dahl J, Zimmermann R, Schafers M. [Myocardial perfusion scintigraphy - short form of the German guideline]. Nuklearmedizin 2013;52: 51-63; quiz N22. Abstract
Maschauer S, Michel K, Tripal P, Buther K, Kuwert T, Schober O, Kopka K, Riemann B, Prante O. Synthesis and in vivo evaluation of an (18)F-labeled glycoconjugate of PD156707 for imaging ETA receptor expression in thyroid carcinoma by positron emission tomography. Am J Nucl Med Mol Imaging 2013;3: 425-436. Abstract
Meister T, Heinzow HS, Woestmeyer C, Lenz P, Menzel J, Kucharzik T, Domschke W, Domagk D. Intraductal ultrasound substantiates diagnostics of bile duct strictures of uncertain etiology. World J Gastroenterol 2013;19: 874-881. Abstract
Palm T, Hemmer K, Winter J, Fricke IB, Tarbashevich K, Sadeghi Shakib F, Rudolph I-M, Hillje A-L, De Luca P, Bahnassawy L'a, Madel R, Viel T, De Siervi A, Jacobs AH, Diederichs S, Schwamborn JC. A systemic transcriptome analysis reveals the regulation of neural stem cell maintenance by an E2F1-miRNA feedback loop. Nucleic Acids Res 2013;41: 3699-3712. Abstract
Rapic S, Backes H, Viel T, Kummer MP, Monfared P, Neumaier B, Vollmar S, Hoehn M, Van der Linden A, Heneka MT, Jacobs AH. Imaging microglial activation and glucose consumption in a mouse model of Alzheimer's disease. Neurobiol Aging 2013;34: 351-354. Abstract
Retser E, Schied T, Skryabin BV, Vogl T, Kanczler JM, Hamann N, Niehoff A, Hermann S, Eisenblätter M, Wachsmuth L, Pap T, van Lent PLEM, Loser K, Roth J, Zaucke F, Ludwig S, Wixler V. Doxycycline-induced expression of transgenic human tumor necrosis factor alpha in adult mice results in psoriasis-like arthritis. Arthritis Rheum 2013;65: 2290-2300. Abstract
Sawatzky A, Tenbrinck D, Jiang X, Burger M. A Variational Framework for Region-Based Segmentation Incorporating Physical Noise Models. J Math Imaging Vision 2013;47(3): 179-209. Abstract
Schmid S, Jiang X, Schäfers K. High-precision lens distortion correction using smoothed thin plate splines. Lect Notes Comput Sc 2013;8048: 432-439. Abstract
Stegger L, Schülke C, Wenning C, Rahbar K, Kies P, Schober O, Schäfers M. Cardiac PET/MRI. Curr Cardiovasc Imaging Rep 2013: 1-10. Abstract
Steingräber AK, Schelhaas S, Faust A, Jacobs AH, Schäfers M, Goerge T. Molecular imaging reveals time course of MMP activity in acute cutaneous vasculitis in vivo. Exp Dermatol 2013;22: 730-735. Abstract
Tenbrinck D, Jiang X. Discriminant Analysis based Level Set Segmentation for Ultrasound Imaging. Lect Notes Comput Sc 2013;8048: 144-151. Abstract
Tenbrinck D, Schmid S, Jiang X, Schäfers K, Stypmann J. Histogram-based Optical Flow for Motion Estimation in Ultrasound Imaging. J Math Imaging Vision 2013;47(1): 138-150.
Viel T, Boehm-Sturm P, Rapic S, Monfared P, Neumaier B, Hoehn M, Jacobs AH. Non-invasive imaging of glioma vessel size and densities in correlation with tumour cell proliferation by small animal PET and MRI. Eur J Nucl Med Mol Imaging 2013;40: 1595-1606. Abstract
Viel T, Monfared P, Schelhaas S, Fricke IB, Kuhlmann MT, Fraefel C, Jacobs AH. Optimizing glioblastoma temozolomide chemotherapy employing lentiviral-based anti-MGMT shRNA technology. Mol Ther 2013;21: 570-579. Abstract
Viel T, Schelhaas S, Wagner S, Wachsmuth L, Schwegmann K, Kuhlmann M, Faber C, Kopka K, Schafers M, Jacobs AH. Early assessment of the efficacy of temozolomide chemotherapy in experimental glioblastoma using [18F]FLT-PET imaging. PLoS One 2013;8: e67911. Abstract
Waschkau B, Faust A, Schäfers M, Bremer C. Performance of a new fluorescence-labeled MMP inhibitor to image tumor MMP activity in vivo in comparison to an MMP-activatable probe. Contrast Media Mol Imaging 2013;8: 1-11. Abstract
Wenning C, Lange PS, Schülke C, Vrachimis A, Mönnig G, Schober O, Eckardt L, Schafers M. Pulmonary vein isolation in patients with paroxysmal atrial fibrillation is associated with regional cardiac sympathetic denervation. EJNMMI Res 2013;3: 81. Abstract
Wenning C, Rahbar K, Vrachimis A, Schober O, Schäfers M, Stegger L. Myocardial perfusion imaging and coronary calcium scoring with a two-slice SPECT/CT system: can the attenuation map be calculated from the calcium scoring CT scan?. Eur J Nucl Med Mol Imaging 2013;40: 1069-1076. Abstract
Worlitzer MMA, Viel T, Jacobs AH, Schwamborn JC. The majority of newly generated cells in the adult mouse substantia nigra express low levels of Doublecortin, but their proliferation is unaffected by 6-OHDA-induced nigral lesion or Minocycline-mediated inhibition of neuroinflammation. Eur J Neurosci 2013;38: 2684-2692. Abstract

2012

Bertrand J, Nitschke Y, Fuerst M, Hermann S, Schäfers M, Sherwood J, Nalesso G, Ruether W, Rutsch F, Dell'Accio F, Pap T. Decreased levels of nucleotide pyrophosphatase phosphodiesterase 1 are associated with cartilage calcification in osteoarthritis and trigger osteoarthritic changes in mice. Ann Rheum Dis 2012;71: 1249-1253. Abstract
Büther K, Compeer MG, De Mey JG, Schober O, Schäfers M, Bremer C, Riemann B, Höltke C. Assessment of Endothelin-A Receptor Expression in Subcutaneous and Orthotopic Thyroid Carcinoma Xenografts in Vivo Employing Optical Imaging Methods. Endocrinology 2012;153: 2907-2918. Abstract
Claesener M, Breyholz H-J, Hermann S, Faust A, Wagner S, Schober O, Schäfers M, Kopka K. Efficient synthesis of a fluorine-18 labeled biotin derivative. Nucl Med Biol 2012;39: 1189-1194. Abstract
Gigengack F, Ruthotto L, Burger M, Wolters C, Jiang X, Schäfers K. Motion Correction in Dual Gated Cardiac PET using Mass-Preserving Image Registration. IEEE Trans Med Imaging 2012;31: 698-712. Abstract
Gigengack F, Ruthotto L, Kösters T, Jiang X, Modersitzki J, Burger M, Hermann S, Schäfers KP. Atlas-Based Segmentation Using Passive Contours. IEEE NSS/MIC 2012: 3015-3016.
Gigengack F, Ruthotto L, Kösters T, Jiang X, Modersitzki J, Burger M, Wolters CH, Schäfers KP. Pipeline for Motion Correction in Dual Gated PET. IEEE NSS/MIC 2012: 2983-2984. Abstract
Hermann S, Starsichova A, Waschkau B, Kuhlmann M, Wenning C, Schober O, Schäfers M. Non-FDG imaging of atherosclerosis: Will imaging of MMPs assess plaque vulnerability?. J Nucl Cardiol 2012;19: 609-617. Abstract
Hesselmann V, Niederstadt T, Dziewas R, Ritter M, Kemmling A, Maintz D, Koehler M, Seifarth H, Jacobs AH, Ringelstein EB, Heindel W. Reperfusion by Combined Thrombolysis and Mechanical Thrombectomy in Acute Stroke: Effect of Collateralization, Mismatch, and Time to and Grade of Recanalization on Clinical and Tissue Outcome. AJNR Am J Neuroradiol 2012: 336-42. Abstract
Hugenberg V, Breyholz H-J, Riemann B, Hermann S, Schober O, Schäfers M, Gangadharmath U, Mocharla V, Kolb H, Walsh J, Zhang W, Kopka K, Wagner S. A new class of highly potent matrix metalloproteinase inhibitors based on triazole-substituted hydroxamates: (radio)synthesis and in vitro and first in vivo evaluation. J Med Chem 2012;55: 4714-4727. Abstract
Hugenberg V, Haufe G. Fluoro-Pummerer rearrangement and analogous reactions. J Fluorine Chem 2012;143: 238-262. Abstract
Jacobs AH, Tavitian B. Noninvasive molecular imaging of neuroinflammation. J Cereb Blood Flow Metab 2012;32: 1393-1415. Abstract
Jansen D, Janssen CIF, Vanmierlo T, Dederen PJ, van Rooij D, Zinnhardt B, Nobelen CLM, Janssen A-L, Hafkemeijer A, Mutsaers MPC, Doedee AMCM, Kuipers AAM, Broersen LM, Mulder M, Kiliaan AJ. Cholesterol and synaptic compensatory mechanisms in Alzheimer's disease mice brain during aging. J Alzheimers Dis 2012;31: 813-826. Abstract
Kuhlmann MT, Cuhlmann S, Hoppe I, Krams R, Evans PC, Strijkers GJ, Nicolay K, Hermann S, Schäfers M. Implantation of a Carotid Cuff for Triggering Shear-stress Induced Atherosclerosis in Mice. J Vis Exp 2012: 3308. Abstract
Mannweiler D. Mathematische Methoden zur Segmentierung von Kardio-MR-Zeitsequenzbildern 2012: epub. Abstract
Paul M, Rahbar K, Gerss J, Kies P, Schober O, Schäfers K, Breithardt G, Schulze-Bahr E, Wichter T, Schäfers M. Microvascular dysfunction in nonfailing arrhythmogenic right ventricular cardiomyopathy. Eur J Nucl Med Mol Imaging 2012;39: 416-420. Abstract
Paulis LE, Geelen T, Kuhlmann MT, Coolen BF, Schäfers M, Nicolay K, Strijkers GJ. Distribution of lipid-based nanoparticles to infarcted myocardium with potential application for MRI-monitored drug delivery. J Control Release 2012;162: 276-285. Abstract
Rahbar K, Seifarth H, Schäfers M, Stegger L, Hoffmeier A, Spieker T, Tiemann K, Maintz D, Scheld HH, Schober O, Weckesser M. Differentiation of malignant and benign cardiac tumors using 18F-FDG PET/CT. J Nucl Med 2012;53: 856-863. Abstract
Ruthotto L, Gigengack F, Burger M, Wolters CH, Jiang X, Schäfers KP, Modersitzki J. A Simplified Pipeline for Motion Correction in Dual Gated Cardiac PET. In: Bildverarbeitung für die Medizin 2012: 51-56. Abstract
Schrigten D, Breyholz HJ, Wagner S, Hermann S, Schober O, Schäfers M, Haufe G, Kopka K. A new generation of radiofluorinated pyrimidine-2,4,6-triones as MMP-targeted radiotracers for positron emission tomography. J Med Chem 2012: 223-232. Abstract
Szymanski MK, Kruizinga S, Tio RA, Willemsen AT, Schäfers MA, Stegger L, Dierckx RA, Hillege HL, Slart RH. Use of gated (13)N-NH(3) micro-PET to examine left ventricular function in rats. Nucl Med Biol 2012;39: 724-729. Abstract
Viel T, Talasila KM, Monfared P, Wang J, Jikeli JF, Waerzeggers Y, Neumaier B, Backes H, Brekka N, Thorsen F, Stieber D, Niclou SP, Winkeler A, Tavitian B, Hoehn M, Bjerkvig R, Miletic H, Jacobs AH. Analysis of the Growth Dynamics of Angiogenesis-Dependent and -Independent Experimental Glioblastomas by Multimodal Small-Animal PET and MRI. J Nucl Med 2012;53: 1135-1145. Abstract
Vrachimis A, Hermann S, Mathe D, Schober O, Schäfers M. Systematic evaluation of 99mTc-tetrofosmin versus 99mTc-sestamibi to study murine myocardial perfusion in small animal SPECT/CT. EJNMMI Res 2012;2: 21. Abstract
Wenning C, Stypmann J, Papavassilis P, Sindermann J, Schober O, Hoffmeier A, Scheld HH, Stegger L, Schäfers M. Left ventricular dilation and functional impairment assessed by gated SPECT are indicators of cardiac allograft vasculopathy in heart transplant recipients. J Heart Lung Transplant 2012;31: 719-728. Abstract
Winkeler A, Boisgard R, Awde AR, Dubois A, Theze B, Zheng J, Ciobanu L, Dolle F, Viel T, Jacobs AH, Tavitian B. The translocator protein ligand [(18)F]DPA-714 images glioma and activated microglia in vivo. Eur J Nucl Med Mol Imaging 2012;39: 811-823. Abstract

2011

Baumann A, Faust A, Law MP, Kuhlmann MT, Kopka K, Schäfers M, Karst U. Metabolite identification of a radiotracer by electrochemistry coupled to liquid chromatography with mass spectrometric and radioactivity detection. Anal Chem 2011;83: 5415-5421. Abstract
Brandes AA, Franceschi E, Gorlia T, Wick W, Jacobs AH, Baumert BG, van den Bent M, Weller M, Stupp R. Appropriate end-points for right results in the age of antiangiogenic agents: Future options for phase II trials in patients with recurrent glioblastoma. Eur J Cancer 2011;48: 896–903. Abstract
Bunk EC, Stelzer S, Hermann S, Schäfers M, Schlatt S, Schwamborn JC. Cellular organization of adult neurogenesis in the Common Marmoset. Aging Cell 2011;10: 28-38. Abstract
Engbers R, Benning M, Heins P, Schäfers K, Burger M. Sparse recovery in myocardial blood flow quantification via PET. IEEE NSS/MIC 2011: 3742-3744.
Euskirchen P, Skaftnesmo K-O, Huszthy PC, Brekka N, Bjerkvig R, Jacobs AH, Miletic H. NUMB does not impair growth and differentiation status of experimental gliomas. Exp Cell Res 2011;317: 2864-2873. Abstract
Fieseler M, Kosters T, Gigengack F, Braun H, Quick HH, Schäfers KP, Jiang X. Motion correction in PET-MRI: A human torso phantom study. IEEE NSS/MIC 2011: 3586-3588.
Galldiks N, Kracht LW, Dunkl V, Ullrich RT, Vollmar S, Jacobs AH, Fink GR, Schroeter M. Imaging of non- or very subtle contrast-enhancing malignant gliomas with [(1)(1)C]-methionine positron emission tomography. Mol Imaging 2011;10: 453-459. Abstract
Gigengack F, Ruthotto L, Burger M, Wolters CH, Jiang X, Schäfers KP. Mass-preserving motion correction of PET: Displacement field vs spline transformation. IEEE NSS/MIC 2011: 3088-3090.
Gigengack F, Ruthotto L, Burger M, Wolters CH, Jiang X, Schäfers KP. Mass-preserving motion correction of dual gated cardiac PET. IEEE NSS/MIC 2011: 3206-3208.
Grabner A, Schnöckel U, Kentrup D, Schäfers M, Reuter S. Strategies for Non-Invasive Molecular Imaging of Acute Allograft Rejection by Gamma Scintigraphy and Positron Emission Tomography. Curr Radiopharm 2011;4(1): 10-23. Abstract
Herzberg S, Rahbar K, Stegger L, Schäfers M, Dugas M. Concept and implementation of a computer-based reminder system to increase completeness in clinical documentation. Int J Med Inform 2011;80: 351-358. Abstract
Hutterer M, Nowosielski M, Putzer D, Waitz D, Tinkhauser G, Kostron H, Muigg A, Virgolini IJ, Staffen W, Trinka E, Gotwald T, Jacobs AH, Stockhammer G. O-(2-18F-fluoroethyl)-L-tyrosine PET predicts failure of antiangiogenic treatment in patients with recurrent high-grade glioma. J Nucl Med 2011;52: 856-864. Abstract
Kaestle C, Winkeler A, Richter R, Sauer H, Hescheler J, Fraefel C, Wartenberg M, Jacobs AH. Imaging herpes simplex virus type 1 amplicon vector-mediated gene expression in human glioma spheroids. Mol Imaging 2011;10: 197-205. Abstract
Kentrup D, Reuter S, Schnöckel U, Grabner A, Edemir B, Pavenstadt H, Schober O, Schäfers M, Schlatter E, Bussemaker E. Hydroxyfasudil-mediated inhibition of ROCK1 and ROCK2 improves kidney function in rat renal acute ischemia-reperfusion injury. PLoS One 2011;6: e26419. Abstract
Kies P, Paul M, Gerss J, Stegger L, Monnig G, Schober O, Wichter T, Schäfers M, Schulze-Bahr E. Impaired cardiac sympathetic innervation in symptomatic patients with long QT syndrome. Eur J Nucl Med Mol Imaging 2011;38: 1899-1907. Abstract
Klose A, Waerzeggers Y, Monfared P, Vukicevic S, Kaijzel EL, Winkeler A, Wickenhauser C, Löwik CWGM, Jacobs AH. Imaging bone morphogenetic protein 7 induced cell cycle arrest in experimental gliomas. Neoplasia 2011;13: 276-285. Abstract
Konik A, Koesters T, Madsen MT, Sunderland JJ. Evaluation of Attenuation and Scatter Correction Requirements as a Function of Object Size in Small Animal PET Imaging. IEEE Trans Nucl Sci 2011;58: 2308-2314.
Kösters T, Schäfers KP, Wübbeling F. EMRECON: An expectation maximization based image reconstruction framework for emission tomography data. IEEE NSS/MIC 2011: 4365-4368.
Lindner O, Burchert W, Bengel FM, Zimmermann R, Vom Dahl J, Schäfers M. Myocardial perfusion scintigraphy in Germany in 2009: utilization and state of the practice. Eur J Nucl Med Mol Imaging 2011;38: 1485-1492. Abstract
Lindner O, Burchert W, Schäfers M. [High radiation exposure by myocardial scintigraphy: Is there a dosage problem?]. Dtsch Med Wochenschr 2011;136: 600. Abstract
Michel K, Büther K, Law MP, Wagner S, Schober O, Hermann S, Schäfers M, Riemann B, Höltke C, Kopka K. Development and evaluation of endothelin-A receptor (radio)ligands for positron emission tomography. J Med Chem 2011;54: 939-948. Abstract
Paul M, Wichter T, Kies P, Gerss J, Wollmann C, Rahbar K, Eckardt L, Breithardt G, Schober O, Schulze-Bahr E, Schäfers M. Cardiac Sympathetic Dysfunction in Genotyped Patients with Arrhythmogenic Right Ventricular Cardiomyopathy and Risk of Recurrent Ventricular Tachyarrhythmias. J Nucl Med 2011;52: 1559-65. Abstract
Pfannkuche A, Buther K, Karthe J, Poenisch M, Bartenschlager R, Trilling M, Hengel H, Willbold D, Haussinger D, Bode JG. c-Src is required for complex formation between the hepatitis C virus-encoded proteins NS5A and NS5B: a prerequisite for replication. Hepatology 2011;53: 1127-1136. Abstract
Rueger MA, Ameli M, Li H, Winkeler A, Rueckriem B, Vollmar S, Galldiks N, Hesselmann V, Fraefel C, Wienhard K, Heiss W-D, Jacobs AH. [18F]FLT PET for non-invasive monitoring of early response to gene therapy in experimental gliomas. Mol Imaging Biol 2011;13: 547-557. Abstract
Schellmann M, Gorlatch S, Meiländer D, Kösters T, Schäfers K, Wübbeling F, Burger M. Parallel medical image reconstruction: from graphics processing units (GPU) to grids. J Supercomp 2011;52: 151-160. Abstract
Schmid S, Tenbrinck D, Jiang X, Schäfers K, Tiemann K, Stypmann J. Histogram-Based Optical Flow for Functional Imaging in Echocardiography. Lect Notes Comput Sc 2011;6854/2011: 477-485. Abstract
Seidler DG, Mohamed NA, Bocian C, Stadtmann A, Hermann S, Schäfers K, Schäfers M, Iozzo RV, Zarbock A, Götte M. The role for decorin in delayed-type hypersensitivity. J Immunol 2011;187: 6108-6119. Abstract
van den Bent MJ, Wefel JS, Schiff D, Taphoorn MJB, Jaeckle K, Junck L, Armstrong T, Choucair A, Waldman AD, Gorlia T, Chamberlain M, Baumert BG, Vogelbaum MA, Macdonald DR, Reardon DA, Wen PY, Chang SM, Jacobs AH. Response assessment in neuro-oncology (a report of the RANO group): assessment of outcome in trials of diffuse low-grade gliomas. Lancet Oncol 2011;12: 583-593. Abstract
Waerzeggers Y, Monfared P, Viel T, Faust A, Kopka K, Schäfers M, Tavitian B, Winkeler A, Jacobs A. Specific biomarkers of receptors, pathways of inhibition and targeted therapies: pre-clinical developments. Br J Radiol 2011;84 Spec No 2: S168-78. Abstract
Waerzeggers Y, Ullrich RT, Monfared P, Viel T, Weckesser M, Stummer W, Schober O, Winkeler A, Jacobs AH. Specific biomarkers of receptors, pathways of inhibition and targeted therapies: clinical applications. Br J Radiol 2011;84 Spec No 2: S179-95. Abstract
Wagner S, Faust A, Breyholz H-J, Schober O, Schäfers M, Kopka K. The MMP inhibitor (R)-2-(N-benzyl-4-(2-[18F]fluoroethoxy)phenylsulphonamido)-N-hydroxy-3-met hylbutanamide: Improved precursor synthesis and fully automated radiosynthesis. Appl Radiat Isot 2011;69: 862-868. Abstract
Wenning C, Stegger D, Hermann S, Schober O, Schäfers M. F-18-FDG Imaging for Atherosclerotic Plaque Characterization. Curr Cardiovasc Imaging Rep 2011;4: 190-198. Abstract
Zander T, Scheffler M, Nogova L, Kobe C, Engel-Riedel W, Hellmich M, Papachristou I, Toepelt K, Draube A, Heukamp L, Buettner R, Ko YD, Ullrich RT, Smit E, Boellaard R, Lammertsma AA, Hallek M, Jacobs AH, Schlesinger A, Schulte K, Querings S, Stoelben E, Neumaier B, Thomas RK, Dietlein M, Wolf J. Early prediction of nonprogression in advanced non-small-cell lung cancer treated with erlotinib by using [(18)F]fluorodeoxyglucose and [(18)F]fluorothymidine positron emission tomography. J Clin Oncol 2011;29: 1701-1708. Abstract

2010

Bovens S, Schulze Elfringhoff A, Kaptur M, Reinhardt D, Schäfers M, Lehr M. 1-(5-Carboxyindol-1-yl)propan-2-one Inhibitors of Human Cytosolic Phospholipase A(2)alpha: Effect of Substituents in Position 3 of the Indole Scaffold on Inhibitory Potency, Metabolic Stability, Solubility, and Bioavailability. J Med Chem 2010;53: 8298–8308. Abstract
Breyholz HJ, Wagner S, Faust A, Riemann B, Höltke C, Hermann S, Schober O, Schäfers M, Kopka K. Radiofluorinated pyrimidine-2,4,6-triones as molecular probes for noninvasive MMP-targeted imaging. ChemMedChem 2010;5: 777-789. Abstract
Buscher K, Judenhofer MS, Kuhlmann MT, Hermann S, Wehrl HF, Schäfers KP, Schäfers M, Pichler BJ, Stegger L. Isochronous assessment of cardiac metabolism and function in mice using hybrid PET/MRI. J Nucl Med 2010;51: 1277-1284. Abstract
Büther F, Ernst I, Dawood M, Kraxner P, Schäfers M, Schober O, Schäfers KP. Detection of respiratory tumour motion using intrinsic list mode-driven gating in positron emission tomography. Eur J Nucl Med Mol Imaging 2010;37: 2315-2327. Abstract
Dawood M, Brune C, Büther F, Jiang X, Burger M, Schober O, Schäfers M, Schäfers KP. A continuity equation based optical flow method for cardiac motion correction in 3 D PET data. Lect Notes Comput Sc 2010;6326: 88-97. Abstract
Dhermain FG, Hau P, Lanfermann H, Jacobs AH, van den Bent MJ. Advanced MRI and PET imaging for assessment of treatment response in patients with gliomas. Lancet Neurol 2010;9: 906-920. Abstract
Drews A, Bovens S, Roebrock K, Sunderkotter C, Reinhardt D, Schäfers M, van der Velde A, Schulze Elfringhoff A, Fabian J, Lehr M. 1-(5-carboxyindol-1-yl)propan-2-one inhibitors of human cytosolic phospholipase A(2)alpha with reduced lipophilicity: synthesis, biological activity, metabolic stability, solubility, bioavailability, and topical in vivo activity. J Med Chem 2010;53: 5165-5178. Abstract
Ernst L, Büther F, Dawood M, Moustakis C, Willich N, Schäfers K, Boelling T. Listmode based PET/CT planning for motion detection in high precision radiotherapy. Strahlenther Onkol 2010;186: 13-14.
Fabritz L, Damke D, Emmerich M, Kaufmann SG, Theis K, Blana A, Fortmuller L, Laakmann S, Hermann S, Aleynichenko E, Steinfurt J, Volkery D, Riemann B, Kirchhefer U, Franz MR, Breithardt G, Carmeliet E, Schäfers M, Maier SKG, Carmeliet P, Kirchhof P. Autonomic modulation and antiarrhythmic therapy in a model of long QT syndrome type 3. Cardiovasc Res 2010;87: 60-72. Abstract
Flotats A, Carrio I, Agostini D, Le Guludec D, Marcassa C, Schäfers M, Somsen GA, Unlu M, Verberne HJ. Proposal for standardization of 123I-metaiodobenzylguanidine (MIBG) cardiac sympathetic imaging by the EANM Cardiovascular Committee and the European Council of Nuclear Cardiology. Eur J Nucl Med Mol Imaging 2010;37: 1802-1812. Abstract
Galldiks N, Kracht LW, Burghaus L, Ullrich RT, Backes H, Brunn A, Heiss W-D, Jacobs AH. Patient-tailored, imaging-guided, long-term temozolomide chemotherapy in patients with glioblastoma. Mol Imaging 2010;9: 40-46. Abstract
Gigengack F, Ruthotto L, Burger M, Wolters CH, Jiang X, Schäfers K. Motion correction of cardiac PET using mass-preserving registration. IEEE NSS/MIC 2010: 3317-3319.
Hohmann C, Radziwill R, Klotz JM, Jacobs AH. Health-related quality of life after ischemic stroke: the impact of pharmaceutical interventions on drug therapy (pharmaceutical care concept). Health Qual Life Outcomes 2010;8: 59. Abstract
Hugenberg V, Fröhlich R, Haufe G. Oxidative desulfurization-fluorination of thioethers Application for the synthesis of fluorinated nitrogen containing building blocks. Org Biomol Chem 2010;8: 5682-5691. Abstract
Hugenberg V, Wagner S, Kopka K, Schober O, Schäfers M, Haufe G. Synthesis of geminal difluorides by oxidative desulfurization-difluorination of alkyl aryl thioethers with halonium electrophiles in the presence of fluorinating reagents and its application for 18F-radiolabeling. J Org Chem 2010;75: 6086-6095. Abstract
Korb A, Hillmann A, Burgis S, Kollias G, Hermann S, Schäfers M, Pap T, Weide T, Gessner A, Pavenstadt H. The TRAF6 binding molecule p62/SQSTM1 is a critical regulator of inflammatory bone destruction. Ann Rheum Dis 2010;69: A19-A19.
Law MP, Schäfers K, Kopka K, Wagner S, Schober O, Schäfers M. Molecular imaging of cardiac sympathetic innervation by 11C-mHED and PET: from man to mouse?. J Nucl Med 2010;51: 1269-1276. Abstract
Law MP, Wagner S, Kopka K, Renner C, Pike VW, Schober O, Schäfers M. Preclinical evaluation of an 18F-labelled beta1-adrenoceptor selective radioligand based on ICI 89,406. Nucl Med Biol 2010;37: 517-526. Abstract
Lindner O, Burchert W, Bengel FM, Zimmermann R, Vom Dahl J, Schäfer W, Schober O, Schäfers M. [Myocardial perfusion scintigraphy 2008 in Germany - results of the fourth query]. Nuklearmedizin 2010;49: 65-72. Abstract
Lucignani G, Schäfers M. PET, CT and MRI characterisation of the atherosclerotic plaque. Eur J Nucl Med Mol Imaging 2010;37: 2398-2402. Abstract
Range FT, Wenning C, Rahbar K, Schober O Schäfers M. Nuclear medicine imaging of the heart and large vessels - State of the art. Zeitschrift für Herz-, Thorax- und Gefäßchirurgie 2010;24: 169-184. Abstract
Reif PS, Strzelczyk A, Rüegg S, Jacobs AH, Haag A, Hermsen A, Sure U, Knake S, Hamer HM, Strik H, Krämer G, Engenhart-Cabilic R, Rosenow F. [Primary brain tumors and brain metastases Symptomatic epilepsy and driving ability - systematic review and expert opinion]. Nervenarzt 2010;81: 1467-1475. Abstract
Reuter S, Schnöckel U, Edemir B, Schröter R, Kentrup D, Pavenstädt H, Schober O, Schlatter E, Gabriels G, Schäfers M. Potential of noninvasive serial assessment of acute renal allograft rejection by 18F-FDG PET to monitor treatment efficiency. J Nucl Med 2010;51: 1644-1652. Abstract
Schäfers M, Schober O, Hermann S. Matrix-metalloproteinases as imaging targets for inflammatory activity in atherosclerotic plaques. J Nucl Med 2010;51: 663-666. Abstract
Schnöckel U, Hermann S, Stegger L, Law M, Kuhlmann M, Schober O, Schäfers K, Schäfers M. Small-animal PET: a promising, non-invasive tool in pre-clinical research. Eur J Pharm Biopharm 2010;74: 50-54. Abstract
Tenbrinck D, Dawood M, Gigengack F, Fieseler M, Jiang X, Schäfers K. Motion correction in Positron Emission Tomography considering Partial Volume Effects in optical flow estimation. IEEE ISBI 2010: 1233-1236. Abstract
Tiemann K, Stypmann J, Landeta F, Wiebe S, Schäfers M, Schober O, Weckesser M, Rahbar K. Three-dimensional echocardiography and 153Sm-EDTMP SPECT/CT in extensive cardiac metastases from osteosarcoma. Eur J Nucl Med Mol Imaging 2010;37: 2406. Abstract
Tsotsalas MM, Kopka K, Luppi G, Wagner S, Law MP, Schäfers M, De Cola L. Encapsulating (111)In in nanocontainers for scintigraphic imaging: synthesis, characterization, and in vivo biodistribution. ACS Nano 2010;4: 342-348. Abstract
Van Camp N, Boisgard R, Kuhnast B, Theze B, Viel T, Gregoire M-C, Chauveau F, Boutin H, Katsifis A, Dolle F, Tavitian B. In vivo imaging of neuroinflammation: a comparative study between [(18)F]PBR111, [ (11)C]CLINME and [ (11)C]PK11195 in an acute rodent model. Eur J Nucl Med Mol Imaging 2010;37: 962-972. Abstract
Waerzeggers Y, Monfared P, Viel T, Winkeler A, Jacobs AH. Mouse models in neurological disorders: applications of non-invasive imaging. Biochim Biophys Acta 2010;1802: 819-839. Abstract
Waerzeggers Y, Rahbar K, Riemann B, Weckesser M, Schäfers M, Hesselmann V, Niederstadt T, Willich N, Stummer W, Paulus W, Schober O, Jacobs AH. PET in the diagnosis and management of patients with brain metastasis: Current role and future perspectives. Cancer Biomark 2010;7: 219-233. Abstract

2009

Büther F, Dawood M, Stegger L, Wübbeling F, Schäfers M, Schober O, Schäfers KP. List mode-driven cardiac and respiratory gating in PET. J Nucl Med 2009;50: 674-681. Abstract
Cerchia L, Esposito CL, Jacobs AH, Tavitian B, de Franciscis V. Differential SELEX in human glioma cell lines. PLoS One 2009;4: e7971. Abstract
Dawood M, Büther F, Schober O, Schäfers M, Schäfers KP. Wieviele respiratorische Gates? Einfluss der Anzahl an Gates auf atemgetriggerte PET Aufnahmen. Nuklearmedizin 2009;48: A23.
Dawood M, Büther F, Stegger L, Jiang X, Schober O, Schäfers M, Schäfers KP. Optimal number of respiratory gates in positron emission tomography: a cardiac patient study. Med Phys 2009;36: 1775-1784. Abstract
Ernst I, Büther F, Dawood M, Kraxner P, Moustakis C, Bolling T, Schober O, Schäfers K, Willich N. PET/CT for movement detection in high precision radiotherapy. Strahlenther Onkol 2009;185: 35-36.
Faust A, Hermann S, Wagner S, Haufe G, Schober O, Schäfers M, Kopka K. Molecular imaging of apoptosis in vivo with scintigraphic and optical biomarkers - a status report. Anticancer Agents Med Chem 2009;9: 968-985. Abstract
Faust A, Waschkau B, Waldeck J, Höltke C, Breyholz H-J, Wagner S, Kopka K, Schober O, Heindel W, Schäfers M, Bremer C. Synthesis and evaluation of a novel hydroxamate based fluorescent photoprobe for imaging of matrix metalloproteinases. Bioconjug Chem 2009;20: 904-912. Abstract
Höltke C, Faust A, Breyholz H-J, Kopka K, Schober O, Riemann B, Bremer C, Schäfers M, Wagner S. Non-invasive approaches to visualize the endothelin axis in vivo using state-of-the-art molecular imaging modalities. Mini Rev Med Chem 2009;9: 1580-1595. Abstract
Höltke C, Law MP, Wagner S, Kopka K, Faust A, Breyholz H-J, Schober O, Bremer C, Riemann B, Schäfers M. PET-compatible endothelin receptor radioligands: synthesis and first in vitro and in vivo studies. Bioorg Med Chem 2009;17: 7197-7208. Abstract
Höltke C, Waldeck J, Kopka K, Heindel W, Schober O, Schäfers M, Bremer C. Biodistribution of a nonpeptidic fluorescent endothelin A receptor imaging probe. Mol Imaging 2009;8: 27-34. Abstract
Hugenberg V, Haufe G. Oxidative Desulfurization-Difluorination of Alkyl Aryl Thioethers: Synthesis of ω-Substituted 1,1-Difluoroalkanes. Synlett 2009: 106-108. Abstract
Kato K, Schober O, Ikeda M, Schäfers M, Ishigaki T, Kies P, Naganawa S, Stegger L. Evaluation and comparison of 11C-choline uptake and calcification in aortic and common carotid arterial walls with combined PET/CT. Eur J Nucl Med Mol Imaging 2009;36: 1622-1628. Abstract
Kopka K, Faust A, Hermann S, Kuhlmann M, Wagner S, Klohs J, Schober O, Wunder A, Schäfers M. 18F-Labeled Isatin as putative biomarker for the specific imaging of activated caspases in apoptosis. J Labelled Comp Radiopharm 2009;52: S39-S39.
Lindner O, Burchert W, Bengel FM, Zimmermann R, vom Dahl J, Schafer W, Schober O, Schäfers M. [Myocardial perfusion scintigraphy 2007 in Germany - results of the query and current status]. Nuklearmedizin 2009;48: 131-137. Abstract
Podichetty AK, Faust A, Kopka K, Wagner S, Schober O, Schäfers M, Haufe G. Fluorinated isatin derivatives Part 1: synthesis of new N-substituted (S)-5-[1-(2-methoxymethylpyrrolidinyl)sulfonyl]isatins as potent caspase-3 and -7 inhibitors. Bioorg Med Chem 2009;17: 2680-2688. Abstract
Podichetty AK, Wagner S, Faust A, Schäfers M, Schober O, Kopka K, Haufe G. Fluorinated isatin derivatives Part 3 New side-chain fluoro-functionalized pyrrolidinyl sulfonyl isatins as potent caspase-3 and -7 inhibitors. Future Med Chem 2009;1: 969-989. Abstract
Podichetty AK, Wagner S, Schroer S, Faust A, Schäfers M, Schober O, Kopka K, Haufe G. Fluorinated isatin derivatives Part 2 New N-substituted 5-pyrrolidinylsulfonyl isatins as potential tools for molecular imaging of caspases in apoptosis. J.Med.Chem. 2009;52: 3484-3495. Abstract
Range FT, Paul M, Schäfers KP, Acil T, Kies P, Hermann S, Schober O, Breithardt G, Wichter T, Schäfers MA. Myocardial perfusion in nonischemic dilated cardiomyopathy with and without atrial fibrillation. J Nucl Med 2009;50: 390-396. Abstract
Reuter S, Schnockel U, Edemir B, Kanzog A, Schroter R, Neugebauer U, Pavenstadt H, Schober O, Schäfers M, Schlatter E, Gabriels G. FDG-Positron Emission Tomography in Diagnosis and Therapy Follow-Up of Acute Rat Renal Allograft Rejection. Am J Transplant 2009;9: 554-555.
Reuter S, Schnöckel U, Schroter R, Schober O, Pavenstädt H, Schäfers M, Gabriels G, Schlatter E. Non-invasive imaging of acute renal allograft rejection in rats using small animal F-FDG-PET. PLoS One 2009;4: e5296. Abstract
Ropinski T, Hermann S, Reich R, Schäfers M, Hinrichs K. Multimodal vessel visualization of mouse aorta PET/CT scans. IEEE Trans Vis Comput Graph 2009;15: 1515-1522. Abstract
Schäfers M, Bengel F, Bull U, Burchert W, Kies P, Kluge R, Krause BJ, Lindner O, Nienaber C, Nowak B, Schafer W, Schober O, Schwaiger M, Silber S, Vom Dahl J, Zimmermann R. [Position paper nuclear cardiology: update 2008]. Nuklearmedizin 2009;48: 71-78. Abstract
Stegger L, Heijman E, Schäfers KP, Nicolay K, Schäfers MA, Strijkers GJ. Quantification of left ventricular volumes and ejection fraction in mice using PET, compared with MRI. J Nucl Med 2009;50: 132-138. Abstract
Stelljes M, Hermann S, Kohler G, Silling G, Berdel WE, Schober O, Schäfers M, Kienast J. Noninvasive assessment of intestinal graft-versus-host disease activity by molecular imaging with 18F-fluorodeoxyglucose positron emission tomography. Bone Marrow Transplant 2009;43: S15-S15.
Ullrich RT, Kracht L, Brunn A, Herholz K, Frommolt P, Miletic H, Deckert M, Heiss W-D, Jacobs AH. Methyl-L-11C-methionine PET as a diagnostic marker for malignant progression in patients with glioma. J Nucl Med 2009;50: 1962-1968. Abstract
Wagner S, Breyholz H-J, Höltke C, Faust A, Schober O, Schäfers M, Kopka K. A new 18F-labelled derivative of the MMP inhibitor CGS 27023A for PET: radiosynthesis and initial small-animal PET studies. Appl Radiat Isot 2009;67: 606-610. Abstract
Wagner S, Breyholz H, Schäfers M, Schober O, Kopka K. 18F-Labeled pyrimidine-2,4,6-triones as potential probes for imaging activated MMPS. J Labelled Comp Radiopharm 2009;52: S40-S40.
Weberpals M, Hermes M, Hermann S, Kummer MP, Terwel D, Semmler A, Berger M, Schäfers M, Heneka MT. NOS2 gene deficiency protects from sepsis-induced long-term cognitive deficits. J Neurosci 2009;29: 14177-14184. Abstract

2008

Benning M, Kösters M, Wübbeling F, Schäfers K, Burger M. A nonlinear variational method for improved quantification of myocardial blood flow using dynamic H215O pET. IEEE NSS 2008: 4472-4477.
Dawood M, Kösters T, Fieseler M, Büther F, Jiang X, Schäfers KP. Motion Correction on Dual ECG and Respiratory Gated 0440 3D Cardiac PET/CT Data. lncs 2008: 155-162.
Faust A, Waschkau B, Waldeck J, Höltke C, Breyholz H-J, Wagner S, Kopka K, Heindel W, Schäfers M, Bremer C. Synthesis and evaluation of a novel fluorescent photoprobe for imaging matrix metalloproteinases. Bioconjug Chem 2008;19: 1001-1008. Abstract
Janssens K, Boussemaere M, Wagner S, Kopka K, Denef C. Beta1-adrenoceptors in rat anterior pituitary may be constitutively active Inverse agonism of CGP 20712A on basal 3',5'-cyclic adenosine 5'-monophosphate levels. Endocrinology 2008;149: 2391-2402. Abstract
Kobbert C, Mollmann C, Schäfers M, Hermann S, Baba HA, Hoffmeier A, Breithardt G, Scheld HH, Weissen-Plenz G, Sindermann JR. Transgenic model of cardiac rhabdomyosarcoma formation. J Thorac Cardiovasc Surg 2008;136: 1178-1186. Abstract
Kopka K, Hermann S, Faust A, Kuhlmann M, Wagner S, Breyholz HJ, Schober O, Schäfers M. Imaging of the "roads to ruin": 18F-labelled isatin as potential tracer for the molecular visualisation of activated caspases in apoptosis. Q J Nucl Med Mol Imaging 2008;52: 21-22.
Law MP, Wagner S, Kopka K, Pike VW, Schober O, Schäfers M. Are [O-methyl-11C]derivatives of ICI 89,406 beta1-adrenoceptor selective radioligands suitable for PET?. Eur J Nucl Med Mol Imaging 2008;35: 174-185. Abstract
Levkau B, Schäfers M, Wohlschlaeger J, von Wnuck Lipinski K, Keul P, Hermann S, Kawaguchi N, Kirchhof P, Fabritz L, Stypmann J, Stegger L, Flogel U, Schrader J, Fischer JW, Hsieh P, Ou YL, Mehrhof F, Tiemann K, Ghanem A, Matus M, Neumann J, Heusch G, Schmid KW, Conway EM, Baba HA. Survivin determines cardiac function by controlling total cardiomyocyte number. Circulation 2008;117: 1583-1593. Abstract
Riemann B, Schäfers KP, Schober O, Schäfers M. Small animal PET in preclinical studies: opportunities and challenges. Q J Nucl Med Mol Imaging 2008;52: 215-221.
Schäfers M. The future of molecular imaging in the clinic needs a clear strategy and a multidisciplinary effort. Basic Res Cardiol 2008;103: 200-202. Abstract
Schnöckel U, Reuter S, Stegger L, Schlatter E, Schäfers KP, Hermann S, Schober O, Gabriels G, Schäfers M. Dynamic 18F-fluoride small animal PET to noninvasively assess renal function in rats. Eur J Nucl Med Mol Imaging 2008;35: 2267-2274. Abstract
Semmler A, Hermann S, Mormann F, Weberpals M, Paxian SA, Okulla T, Schäfers M, Kummer MP, Klockgether T, Heneka MT. Sepsis causes neuroinflammation and concomitant decrease of cerebral metabolism. J Neuroinflammation 2008;5: 38. Abstract
Stegger L, Schäfers M, Weckesser M, Schober O. EANM-ESR white paper on multimodality imaging. Eur J Nucl Med Mol Imaging 2008;35: 677-680. Abstract
Stelljes M, Hermann S, Albring J, Kohler G, Loffler M, Franzius C, Poremba C, Schlosser C, Volkmann S, Opitz C, Bremer C, Kucharzik T, Silling G, Schober O, Berdel WE, Schäfers M, Kienast J. Clinical molecular imaging in intestinal graft-versus-host disease: mapping of disease activity, prediction, and monitoring of treatment efficiency by positron emission tomography. Blood 2008;111: 2909-2918. Abstract
Waldeck J, Hager F, Höltke C, Lanckohr C, von Wallbrunn A, Torsello G, Heindel W, Theilmeier G, Schäfers M, Bremer C. Fluorescence reflectance imaging of macrophage-rich atherosclerotic plaques using an alphavbeta3 integrin-targeted fluorochrome. J Nucl Med 2008;49: 1845-1851. Abstract

2007

Dawood M, Fieseler M, Büther F, Jiang X, Schäfers KP. A Multi-resolution Optical Flow Based Approach to Respiratory Motion Correction in 3D PET/CT Images. Lect Notes Comput Sc 2007: 314-322. Abstract
Kummer C, Winkeler A, Dittmar C, Bauer B, Rueger MA, Rueckriem B, Heneka MT, Vollmar S, Wienhard K, Fraefel C, Heiss W-D, Jacobs AH. Multitracer positron emission tomographic imaging of exogenous gene expression mediated by a universal herpes simplex virus 1 amplicon vector. Mol Imaging 2007;6: 181-192. Abstract
Miletic H, Fischer Y, Litwak S, Giroglou T, Waerzeggers Y, Winkeler A, Li H, Himmelreich U, Lange C, Stenzel W, Deckert M, Neumann H, Jacobs AH, von Laer D. Bystander killing of malignant glioma by bone marrow-derived tumor-infiltrating progenitor cells expressing a suicide gene. Mol Ther 2007;15: 1373-1381. Abstract
Rueger MA, Kracht LW, Hilker R, Thiel A, Sobesky J, Winkeler A, Thomas AV, Heneka MT, Graf R, Herholz K, Heiss WD, Jacobs AH. Role of in vivo imaging of the central nervous system for developing novel drugs. Q J Nucl Med Mol Imaging 2007;51: 164-181. Abstract
Saydam O, Saydam N, Glauser DL, Pruschy M, Dinh-Van V, Hilbe M, Jacobs AH, Ackermann M, Fraefel C. HSV-1 amplicon-mediated post-transcriptional inhibition of Rad51 sensitizes human glioma cells to ionizing radiation. Gene Ther 2007;14: 1143-1151. Abstract
Wagner S, Breyholz H-J, Law MP, Faust A, Höltke C, Schroer S, Haufe G, Levkau B, Schober O, Schäfers M, Kopka K. Novel fluorinated derivatives of the broad-spectrum MMP inhibitors N-hydroxy-2(R)-[[(4-methoxyphenyl)sulfonyl](benzyl)- and (3-picolyl)-amino]-3-methyl-butanamide as potential tools for the molecular imaging of activated MMPs with PET. J Med Chem 2007;50: 5752-5764. Abstract
Winkeler A, Sena-Esteves M, Paulis LEM, Li H, Waerzeggers Y, Ruckriem B, Himmelreich U, Klein M, Monfared P, Rueger MA, Heneka M, Vollmar S, Hoehn M, Fraefel C, Graf R, Wienhard K, Heiss WD, Jacobs AH. Switching on the lights for gene therapy. PLoS One 2007;2: e528. Abstract