Boswellia-based food supplements

The resin of Boswellia serrata Roxb. ex Colebr. (Indian frankincense) has long been used in traditional medicine. As no medicinal product based on this resin is authorised in Germany, a broad market for food supplements has established itself.

As part of our investigations, commercially available products were tested for authenticity using thin-layer chromatography and UHPLC with UV detection (200 and 250 nm), and six pharmacologically relevant boswellic acids (11-keto-β-boswellic acid, 3-O-acetyl-11-keto-β-boswellic acid, α-boswellic acid, β-boswellic acid, 3-O-acetyl-α-boswellic acid, 3-O-acetyl-β-boswellic acid)

 

© IPBP / Brouns

Conclusion:

None of the products tested met the declared levels of boswellic acids, although the term itself is not uniformly defined: some manufacturers refer to the total fraction of triterpenic acids, whereas this study specifically analysed six pharmacologically relevant individual compounds. Three products also exhibited a chromatographic fingerprint that did not match that of Boswellia serrata. Two of these simply declared ‘frankincense extract’ without specifying the species – an assessment is hardly possible here, as ‘frankincense’ encompasses resins from around 24 different Boswellia species, which differ considerably in their composition. For consumers and for quality control, the lack of a species specification therefore remains a key issue.

 

Product reviews (including images):

© IPBP / Brouns

Composition (per capsule):

Boswellia serrata extract: 100 mg

Boswellic acids: 80 mg

Identity test: complies (250 nm)

Assay: 5.6% boswellic acids (calculation of [mg] per capsule not possible, as the net fill weight of a capsule could not be determined)

© IPBP / Brouns

Nutritional information (per capsule):


Frankincense extract: 400 mg
Boswellic acids: 240 mg (60 %)


Identity test: complies

Assay: 158 mg BA per capsule

© IPBP / Brouns

Nutritional information (per capsule):

Frankincense extract: 400 mg
Boswellic acids: 280 mg


Identity test: complies

Assay: 102 mg BA per capsule

© IPBP / Brouns

Nutritional information (per capsule):


Frankincense extract: 400 mg
Boswellic acids: 240 mg


Identity test: complies

Assay: 100 mg BA per capsule

© IPBP / Brouns

Nutritional information (per capsule):


Frankincense extract: 200 mg
Boswellic acids: 170 mg


Identity test: complies

Assay: 54 mg BA per capsule

© IPBP / Brouns

Composition (per capsule):


Boswellin HBD DC extract (5-10:1 Boswellia serrata): 500 mg
Boswellic acids: 350 mg

Identity test: complies

Assay: 140 mg BA per capsule

© IPBP / Brouns

Nutritional information (per capsule):


Frankincense extract: 500 mg
Boswellia acids: 425 mg

Identity test: does not comply

© IPBP / Brouns

Nutritional information (per capsule):


Boswellia serrata extract: 400 mg
Boswellic acids: 272 mg (min. 68%)

Identity test: does not comply

© IPBP / Brouns

Nutritional information (per capsule):

Frankincense extract: 450 mg

Boswellic acids: 382.5 mg (85%)

Identity test: does not comply