Flexible Funds projects

Flexible Funds projects are interdisciplinary research projects carried out by senior researchers and independent junior researchers.

  • News item dated 15.09.2017: One Million Euros in funding for research – funding from Cells-in-Motion Cluster of Excellence for ten new interdisciplinary research projects
  • Application

    The programme is currently being revised.

  • Funded projects

    • FF-2017-04 – A biomimetic platform mimicking the implantation niche of mouse embryos
      Principal investigators: Ivan Bedzhov, Britta Trappmann
      Project time: 11/2017 - 12/2018
    • FF-2017-07 – Tunneling nanotubes and mitochondria: Intracellular interactions and intercellular trafficking investigated with new intein-based techniques
      Principal investigators: Karin Busch, Henning Mootz
      Project time: 11/2017 - 12/2018
    • FF-2017-08 – The role of integrins in platelet cohesion with tumor cells and platelet-mediated tumor cell adhesion
      Principal investigators: Johannes A. Eble, Carsten Höltke
      Project time: 11/2017 - 12/2018
    • FF-2017-10 – Biohybrid neurosynaptic chips interfaced with nanostructured, integrated optics
      Principal investigators: Jürgen Klingauf, Wolfram Pernice
      Project time: 11/2017 - 12/2018
    • FF-2017-13 – Exploring the role of vesicle transport and cell morphology during neuronal polarization: imaging and modeling approaches
      Principal investigators: Jan-Frederik Pietschmann, Andreas Püschel
      Project time: 11/2017 - 12/2018
    • FF-2017-14 – Characterization of cell-environment interactions affecting single-cell motility in vivo
      Principal investigators: Erez Raz, Martin Burger, Daniel Tenbrinck
      Project time: 11/2017 - 12/2018
    • FF-2017-17 – Combining myeloid precursor immortalization, genome editing and genetic reporter systems for imaging of monocyte trafficking in inflammation and ischemia
      Principal investigators: Johannes Roth, Michael Schäfers
      Project time: 11/2017 - 12/2018
    • FF-2017-19 – Characterization of the particle drift behavior of a novel PET detector concept using heavy dielectric organometallic liquids
      Principal investigators: Klaus Schäfers, Christian Weinheimer
      Project time: 11/2017 - 12/2018
    • FF-2017-21 – Analysis of the cytoskeleton in controlling endoglin-dependent endothelial cell shape changes in response to mechanical forces
      Principal investigators: Arndt Siekmann, Britta Trappmann
      Project time: 11/2017 - 12/2018
    • FF-2017-24 Nanoscale control of plasma membrane organization
      Principal investigators: Roland Wedlich-Söldner, Wolfram Pernice
      Project time: 11/2017 - 12/2018
    • FF-2016-01 – Rotational motion in epithelial morphogenesis: Analysis of conserved molecular mechanisms
      Principal investigators: Sven Bogdan, Klaus Ebnet
      Project time: 07/2016 - 06/2018
    • FF-2016-03 – Symmetry Breaking in Neurons
      Principal investigators: Christian Engwer, Milos Galic
      Project time: 07/2016 - 10/2018
    • FF-2016-05 – Cells Eating: is there a distinct complement-mediated sinking-in mode of phagocytosis?
      Principal investigators: Peter J. Hanley, Ivan Liashkovich
      Project time: 07/2016 - 10/2018
    • FF-2016-06 – FIM4D: Automated FIM-based in-vial activity monitoring and tracking for locomotion analysis of Drosophila larvae
      Principal investigators: Xiaoyi Jiang, Christian Klämbt
      Project time: 07/2016 - 10/2018
    • FF-2016-09 – A chemo-enzymatic approach for posttranscriptional RNA-labeling in living zebrafish
      Principal investigators: Sebastian Leidel, Andrea Rentmeister
      Project time: 07/2016 - 10/2018
    • FF-2016-10 – The diagnostic and prognostic value of FDG-PET-MRI and its correlation with cellular and biologic features in primary CNS lymphoma patients
      Principal investigators: Georg Lenz, Oliver Grauer, Werner Paulus, Michael Schäfers
      Project time: 07/2016 - 10/2018
    • FF-2016-11 – Effects of newly generated, peripherally-selective, anti-inflammatory kappa-opioid receptor agonists in the treatment of progressive CNS inflammation and neurodegeneration
      Principal investigators: Karin Loser, Bernhard Wünsch, Sonja Ständer
      Project time: 07/2016 - 10/2018
    • FF-2016-12 – Cyclodextrin based copolymer vesicles for delivery of labeled lipids and other cargo into cells
      Principal investigators: Bart Jan Ravoo, Armido Studer, Volker Gerke
      Project time: 07/2016 - 12/2017
    • FF-2016-13 – Novel tools for mRNA labeling in Drosophila
      Principal investigators: Sebastian Rumpf, Andrea Rentmeister
      Project time: 07/2016 - 10/2018
    • FF-2016-15 – Quantitative analysis of local subcellular cell junction activity by JAIL formation and its impact on endothelial cell migration and barrier function
      Principal investigators: Jochen Seebach, Benedikt Wirth
      Project time: 07/2016 - 10/2018
    • FF-2016-16 – Synthesis, photophysics and preclinical application of targeted absorbers for photoacoustic imaging
      Principal investigators: Cristian Strassert, Andreas Faust
      Project time: 07/2016 - 10/2018
    • FF-2016-17 – Mechanisms of human sperm rheotaxis
      Principal investigators: Timo Strünker, Carsten Fallnich
      Project time: 07/2016 - 10/2018
    • FF-2015-01 – Mechanical adaptation of motile cells in development and immune response
      Principal investigators: Timo Betz
      Project time: 07/2015 - 10/2017
    • FF-2015-02 – In vitro and in vivo investigations of lipid-based signaling mechanisms
      Principal investigators: Milos Galic, Kay Grobe
      Project time: 07/2015 - 06/2016
    • FF-2015-03 – CCR6 as a marker of CD4+Th17+ T cells in inflammation: development of specific imaging and therapeutic tools
      Principal investigators: Günter Haufe, Lydia Sorokin
      Project time: 07/2015 - 10/2017
    • FF-2015-04 – Intravital direct visualization of hypoxia using a genetically encoded optical sensor
      Principal investigators: Friedemann Kiefer, Michael Schäfers
      Project time: 07/2015 - 10/2017
    • FF-2015-05 – Direct neuronal Interfacing on functionalized microstructured coverslips for imaging synapse development and plasticity
      Principal investigators: Jürgen Klingauf, Markus Missler
      Project time: 07/2015 - 10/2017
    • FF-2015-07 – Mechanobiology, Mathematical Modeling and Simulation of Forces During Tissue Morphogenesis
      Principal investigators: Maja Matis, Mario Ohlberger, Angela Stevens
      Project time: 07/2015 - 10/2017
    • FF-2015-08 – Calcium mediated actin rearrangement (CMA) in podocyte development and pathogenesis
      Principal investigators: Hermann Pavenstädt, Roland Wedlich-Söldner
      Project time: 07/2015 - 06/2016
    • FF-2015-12 – Photoacoustic Molecular Imaging in Rheumatoid Arthritis
      Principal investigators: Sven Hermann, Thomas Vogl
      Project time: 07/2015 - 10/2017
    • FF-2014-01 – Molecular mechanisms controlling DC migration in CNS autoimmunity
      Principal investigators: Judith Alferink, Martin Bähler
      Project time: 07/2014 - 06/2016
    • FF-2014-03 – In vivo intratumoral accumulation of cytotoxic drugs by tumor vascular infarction with retargeted tissue factor tTF-NGR
      Principal investigators: Wolfgang Berdel, Carsten Höltke, Stefan Wagner, Bernhard Wünsch
      Project time: 04/2014 - 03/2015
    • FF-2014-05 – Mechanism of TREK1-mediated T lymphocyte transmigration via the blood-brain-barrier
      Principal investigators: Stefan Bittner, Thomas Budde, Petra Ehling, Sven Meuth, Heinz Wiendl
      Project time: 07/2014 - 06/2016
    • FF-2014-06 – Analysis of cell-cell interactions during neuronal migration in the developing cortex by live cell imaging and cell shape quantification
      Principal investigators: Martin Burger, Andreas Püschel
      Project time: 07/2014 - 06/2016
    • FF-2014-07 – Intravital microscopy of neutrophil extravasation into the peritoneum
      Principal investigators: Konrad Buscher, Jian Song, Benedikt Wirth
      Project time: 07/2014 - 06/2016
    • FF-2014-09 – The impact of cellular and tissue viscoelasticity on cell migration and morphogenesis
      Principal investigators: Cornelia Denz, Erez Raz
      Project time: 07/2014 - 06/2017
    • FF-2014-12 – Metabolic crosstalk across the blood brain barrier
      Principal investigators: Christian Klämbt, Matthias Letzel, Stefanie Limmer
      Project time: 07/2014 - 06/2016
    • FF-2014-15 – Global analysis of shear stress regulated enhancer elements in endothelial cells
      Principal investigators: Hans-Joachim Schnittler, Arndt Siekmann
      Project time: 07/2014 - 06/2017
    • FF-2013-03 – Analysis of new actin regulators controlling cell shape, cell dynamics and cell polarity in Drosophila hemocytes
      Principal investigators: Sven Bogdan, Xiaoyi Jiang
      Project time: 07/2013 - 06/2016
    • FF-2013-09 – Label-free detection of lipid domains in biological membranes
      Principal investigators: Carsten Fallnich, Volker Gerke
      Project time: 07/2013 - 06/2016
    • FF-2013-10 – Targeted photoinduced killing of bacterial pathogens utilizing maltohexaose-conjugated photoprobes
      Principal investigators: Andreas Faust, Bettina Löffler
      Project time: 07/2013 - 06/2016
    • FF-2013-16 – PET imaging of freely moving mice
      Principal investigators: Xiaoyi Jiang, Frank Wübbeling, Klaus Schäfers
      Project time: 07/2013 - 06/2016
    • FF-2013-17 – Studying Cells in Motion by Complementary Magnetic Resonance and Mass Spectrometric Imaging
      Principal investigators: Uwe Karst, Cornelius Faber
      Project time: 07/2013 - 06/2016
    • FF-2013-14 – Imaging of Vegfc protein in zebrafish using incorporation of unnatural amino acids
      Principal investigator: Wiebke Herzog
      Project time: 07/2013 - 06/2015
    • FF-2013-20 – Development and application of intein chemistry-based specific probes for macrophage fate determination during chronic inflammatory processes
      Principal investigators: Henning Mootz, Friedemann Kiefer
      Project time: 07/2013 - 06/2015
    • FF-2013-24 – Monitoring molecular mechanisms of monocyte migration during inflammatory processes in vivo
      Principal investigators: Michael Schäfers, Johannes Roth
      Project time: 07/2013 - 06/2015
    • FF-2013-28 – Development of novel, dual purpose, MOBSAM-based, specific inhibitors for MMP-2/9 to image and investigate their activity in inflammatory pathologies in vivo
      Principal investigators: Lydia Sorokin, Günter Haufe
      Project time: 07/2013 - 06/2015
    • FF-2013-29 – Lipid Rafts – Mathematical Modeling, Molecular Dynamics, and Experiments
      Principal investigators: Angela Stevens, Volker Gerke, Andreas Heuer
      Project time: 07/2013 - 06/2015
    • FF-2013-33 – Identifying Differential Mechanical Constraints in Leukocyte Extravasation by 4D Mathematical Image and Motion Analysis
      Principal investigators: Dietmar Vestweber, Christoph Brune
      Project time: 07/2013 - 06/2015