Beteiligung am Exzellenzcluster

CiM-Koordinator
CiM Principal Investigator
Mitglied des Vorstandes
Mitglied des Wissenschaftlichen Lenkungsausschusses
Mitglied des Ausschusses für Aus- und Weiterbildung
Mitglied der CiM-IMPRS Graduiertenschule

  • Forschungsgebiet A.3: Funktionelle Membrandomänen bei neuronaler und nicht-neuronaler Kompartimentierung
  • Forschungsgebiet A.4: Monitoring molekularer Mechanismen der Monozytenmigration in entzündlichen Prozessen in vivo
  • Forschungsgebiet B.1: Ausbildung und Eigenschaften von epithelialen und endothelialen Zellbarrieren
  • Projekt FF-2016-12: Cyclodextrin based copolymer vesicles for delivery of labeled lipids and other cargo into cells (Bart Jan Ravoo, Armido Studer, Volker Gerke, Projektlaufzeit: 07/2016 - 06/2018)
  • Projekt FF-2013-09: Markierungsfreie Detektion von Lipiddomänen in biologischen Membranen (Carsten Fallnich, Volker Gerke, Projektlaufzeit: 07/2013 - 06/2015)
  • Projekt FF-2013-29: Lipid Rafts – Mathematische Modellierung, Moleküldynamik und Experiment (Angela Stevens, Volker Gerke, Andreas Heuer, Projektlaufzeit: 07/2013 - 06/2015)
© CiM - Peter Grewer

„Wissenschaft ist nur gut, wenn sie auch kreativ ist.“

Prof. Volker Gerke interessiert sich für die Organisation zellulärer Membranen. Mit seiner Forschungsgruppe untersucht er, wie Membrandynamik den intrazellulären Transport und die Wanderung von Zellen im Verlauf von Entzündungsreaktionen beeinflusst. Zum Interview

CiM-Publikationen

alle Publikationen von Volker Gerke (PubMed)

Accepted for publication

Rakers L, Grill D, Matos A, Wulff S, Wang D, Börgel J, Körsgen M, Arlinghaus HF, Galla H-J, Gerke V, Glorius F. Novel addressable cholesterol analogs for live imaging of cellular membranes. Cell Chem Biol: accepted for publication.

2017

Biesemann A, Gorontzi A, Barr F, Gerke V. Rab35 protein regulates evoked exocytosis of endothelial Weibel-Palade bodies. J Biol Chem 2017;292: 11631-11640. Abstract
Boye TL, Maeda K, Pezeshkian W, Sonder SL, Haeger SC, Gerke V, Simonsen AC, Nylandsted J. Annexin A4 and A6 induce membrane curvature and constriction during cell membrane repair. Nat Commun 2017;8: 1623. Abstract
Chehab T, Santos NC, Holthenrich A, Koerdt SN, Disse J, Schuberth C, Nazmi AR, Neeft M, Koch H, Man KNM, Wojcik SM, Martin TFJ, van der Sluijs P, Brose N, Gerke V. A novel Munc13-4/S100A10/annexin A2 complex promotes Weibel-Palade body exocytosis in endothelial cells. Mol Biol Cell 2017;28: 1688-1700. Abstract
de Vries WC, Grill D, Tesch M, Ricker A, Nusse H, Klingauf J, Studer A, Gerke V, Ravoo BJ. Reversible Stabilization of Vesicles: Redox-Responsive Polymer Nanocontainers for Intracellular Delivery. Angew Chem Int Ed Engl 2017;56: 9603-9607. Abstract
Koerdt SN, Gerke V. Annexin A2 is involved in Ca2+-dependent plasma membrane repair in primary human endothelial cells. Biochim Biophys Acta 2017;1864: 1046-1053. Abstract
Rieger S, Grill D, Gerke V, Fallnich C. Quantitative spontaneous Raman scattering spectroscopy in artificial binary lipid membranes: Quantitative Raman spectroscopy in lipid membranes. J Raman Spectrosc 2017;48: 1264-1269. Abstract

2016

Brinkmann BF, Steinbacher T, Hartmann C, Kummer D, Pajonczyk D, Mirzapourshafiyi F, Nakayama M, Weide T, Gerke V, Ebnet K. VE-cadherin interacts with cell polarity protein Pals1 to regulate vascular lumen formation. Mol Biol Cell 2016;27: 2811-2821. Abstract
Gerke V. Annexins A2 and A8 in endothelial cell exocytosis and the control of vascular homeostasis. Biol Chem 2016;397: 995-1003. Abstract

2015

Nammalwar RC, Heil A, Gerke V. Ezrin interacts with the scaffold protein IQGAP1 and affects its cortical localization. Biochim Biophys Acta 2015;1853: 2086-2094. Abstract
Tuncay H, Brinkmann BF, Steinbacher T, Schurmann A, Gerke V, Iden S, Ebnet K. JAM-A regulates cortical dynein localization through Cdc42 to control planar spindle orientation during mitosis. Nat Commun 2015;6: 8128. Abstract

2014

Drucker P, Pejic M, Grill D, Galla H-J, Gerke V. Cooperative binding of annexin A2 to cholesterol- and phosphatidylinositol-4,5-bisphosphate-containing bilayers. Biophys J 2014;107: 2070-2081. Abstract
Quiskamp N, Poeter M, Raabe CA, Hohenester UM, Konig S, Gerke V, Rescher U. The tumor suppressor annexin A10 is a novel component of nuclear paraspeckles. Cell Mol Life Sci 2014;71: 311-329. Abstract
Wennmann DO, Schmitz J, Wehr MC, Krahn MP, Koschmal N, Gromnitza S, Schulze U, Weide T, Chekuri A, Skryabin BV, Gerke V, Pavenstadt H, Duning K, Kremerskothen J. Evolutionary and Molecular Facts Link the WWC Protein Family to Hippo Signaling. Mol Biol Evol 2014;31: 1710-1723. Abstract

2013

Brandherm I, Disse J, Zeuschner D, Gerke V. cAMP-induced secretion of endothelial von Willebrand factor is regulated by a phosphorylation/dephosphorylation switch in annexin A2. Blood 2013;122: 1042-1051. Abstract
Drucker P, Pejic M, Galla H-J, Gerke V. Lipid segregation and membrane budding induced by the peripheral membrane binding protein annexin A2. J Biol Chem 2013;288: 24764-24776. Abstract
Ghavampour S, Lange C, Bottino C, Gerke V. Transcriptional profiling of human monocytes identifies the inhibitory receptor CD300a as regulator of transendothelial migration. PLoS One 2013;8: e73981. Abstract
Kluger MS, Clark PR, Tellides G, Gerke V, Pober JS. Claudin-5 controls intercellular barriers of human dermal microvascular but not human umbilical vein endothelial cells. Arterioscler Thromb Vasc Biol 2013;33: 489-500. Abstract
Musiol A, Gran S, Ehrhardt C, Ludwig S, Grewal T, Gerke V, Rescher U. Annexin A6-balanced late endosomal cholesterol controls influenza a replication and propagation. MBio 2013;4: e00608-13. Abstract
Peddibhotla SSD, Brinkmann BF, Kummer D, Tuncay H, Nakayama M, Adams RH, Gerke V, Ebnet K. Tetraspanin CD9 links junctional adhesion molecule-A to alphavbeta3 integrin to mediate basic fibroblast growth factor-specific angiogenic signaling. Mol Biol Cell 2013;24: 933-944. Abstract

2012

Iden S, Misselwitz S, Peddibhotla SSD, Tuncay H, Rehder D, Gerke V, Robenek H, Suzuki A, Ebnet K. aPKC phosphorylates JAM-A at Ser285 to promote cell contact maturation and tight junction formation. J Cell Biol 2012;196: 623-639. Abstract
Nazmi AR, Ozorowski G, Pejic M, Whitelegge JP, Gerke V, Luecke H. N-terminal acetylation of annexin A2 is required for S100A10 binding. Biol Chem 2012;393: 1141-1150. Abstract
Tcatchoff L, Andersson S, Utskarpen A, Klokk TI, Skanland SS, Pust S, Gerke V, Sandvig K. Annexin A1 and A2: roles in retrograde trafficking of Shiga toxin. PLoS One 2012;7: e40429. Abstract