Signal Transduction (Second Edition)

Author(s): Bastien D. Gomperts, IJsbrand M. Kramer and Peter E.R. Tatham
ISBN: 978-0-12-369441-6
Elsevier 2009

A reference on cellular-signalling processes, Signal Transduction (Second Edition) details the sources, key observations, and experiments that set the scene for recent and current scientific endeavor. Beginning with a historical overview, this book discusses how the concept of chemical messengers arose in the early twentieth century and shaped our current understanding of the action of hormones, cytokines, neurotransmitters, and growth factors.

Signal Transduction second edition further examines more complex signalling cascades, emanating from classic receptors, as well as adhesion molecules, involved in processes such as vision, smell, inflammation, innate and adaptive immunity, glucose homeostasis, cell-fate decisions, cell differentiation, and cell transformation. This timely revision concludes with a discourse on the targeting of signal-transduction cascades in the treatment of cancer and the structure of protein domains key to the assembly of signalling complexes.

—
Das obige Buch gehört zu den gut 1.000 dauerhaft von der ZB Med gekauften Online-Büchern des Elsevier-Verlags der Jahre 1995-2008 und 2009, die in den folgenden Sachgebieten erschienen sind: Biochemistry, Genetics and Molecular Biology; Forensics; Immunology and Microbiology; Medicine and Dentistry; Neuroscience; Pharmacology, Toxicology and Pharmaceutical Science; Psychology.

Stem Cells

Autoren: Christine Mummery, Ian Wilmut, Anja Van De Stolpe, Bernard Roelen
ISBN: 978-0-12-381535-4
Elsevier 2011

In the past decades our understanding of stem cell biology has increased tremendously. Many types of stem cells have been discovered in tissues of which everyone presumed were unable to regenerate in adults; these include particularly the heart and the brain. There is vast interest in stem cells from biologists and clinicians who see the potential for regenerative medicine and future treatments for chronic diseases like Parkinson, diabetes and spinal cord lesions based on the use of stem cells and entrepreneurs in biotechnology who expect new commercial applications ranging from drug discovery to transplantation therapies. As is often the case in science, many early claims turned out to be different from those expected. Embryonic stem cell therapies have not moved rapidly into clinical practice. Adult stem cells certainly have given certain degrees of success but not nearly to the extent that advocates would have wished for. Some claims of early successes in adult stem cell therapies have not been sustained in double-blinded, randomized clinical trials. Some claims are now close to routine therapy. Some of the claims not supported by evidence have nevertheless reached private clinical practice so that „stem cell tourism“ is beginning to reach exaggerated proportions. Stem Cells provides the reader background information on stem cells in a clear and well-organized manner. It provides the non-stem cell expert with an understandable review of the history, current state of affairs, and facts and fiction of the promises of stem cells. It distinguishes itself from the multiplicity of websites on the subject of stem cells by being scientifically, politically and ethically neutral, explaining pros and cons for stem cells of every sort with the intention of reaching a wide readership ranging from advanced students and patient advocacy groups to clinicians, specialists and early phase medics in training. By providing the background scientific and social information, it provides readers with the information they require to form their own opinions on the use of stem cells on the basis of facts rather than hype.

—
Das obige Buch gehört zu den gut 1.000 dauerhaft von der ZB Med gekauften Online-Büchern des Elsevier-Verlags der Jahre 1995-2008, 2009 und 2010-2011, die in den folgenden Sachgebieten erschienen sind: Biochemistry, Genetics and Molecular Biology; Forensics; Immunology and Microbiology; Medicine and Dentistry; Neuroscience; Pharmacology, Toxicology and Pharmaceutical Science; Psychology.

Science and the Media: Delgado’s Brave Bulls and the Ethics of Scientific Disclosure

Author(s): Peter J. Snyder, Linda C. Mayes and Dennis D. Spencer
ISBN: 978-0-12-373679-6
Elsevier 2009

Of great utility for every scientist faced with publicizing their discoveries via the media, Science and the Media addresses questions of responsibility for the balance and accuracy of scientific reporting, and attempts to be a guide for the scientist in their quest to inform the general public about their research in honest, truthful, and still interesting ways. Case studies by leading scholars in the fields of bioethics (pharmaceutical research (Declan Doogan, Senior VP Pfizer), medical journal editing (Jerome Kassirer, former editor of NEJM), science journalism, philosophy of science, history of medicine (John Warner, chair history of medicine Yale), public health (Ruth Katz, Dean public health, George Washington University), and philosophy of religion (Reverend Wesley Carr, former Dean of Westminster) illustrate positions and points of view and offer unique perspectives on the complex dance between science and the media.

—
Das obige Buch gehört zu den gut 1.000 dauerhaft von der ZB Med gekauften Online-Büchern des Elsevier-Verlags der Jahre 1995-2008 und 2009, die in den folgenden Sachgebieten erschienen sind: Biochemistry, Genetics and Molecular Biology; Forensics; Immunology and Microbiology; Medicine and Dentistry; Neuroscience; Pharmacology, Toxicology and Pharmaceutical Science; Psychology.