Participation in “Cells in Motion”

  • Management Board member of the CiM-IMPRS Graduate Programme
  • Research interests: image analysis, pattern recognition, machine learning
  • Projekt FF-2016-06: FIM4D: Automated FIM-based in-vial activity monitoring and tracking for locomotion analysis of Drosophila larvae (Xiaoyi Jiang, Christian Klämbt, project time: 07/2016 - 10/2018)
  • Project FF-2013-03: Analysis of new actin regulators controlling cell shape, cell dynamics and cell polarity in Drosophila hemocytes (Sven Bogdan, Xiaoyi Jiang; project time: 07/2013 - 06/2015)
  • Project FF-2013-16: PET imaging of freely moving mice (Xiaoyi Jiang, Frank Wübbeling, Klaus Schäfers; project time: 07/2013 - 06/2016)

© CiM - Peter Grewer

“We give meaning to biomedical images“ – an interview

Prof Xiaoyi Jiang is developing methods of producing and analysing biomedical images. These new methods make it possible to track the movement of individual cells or even entire organisms. For Prof Jiang it is especially important to develop elegant methods which work for a whole range of applications.

  • Patents in the research focus “cell dynamics and imaging”

    • Jiang X, Klämbt C, Risse B, Valkov D. Verfahren und Vorrichtung zur Erfassung wenigsten eines Tieres. DE 102012016122; 20/02/2014.
    • Tenbrinck D, Stypmann J, Jiang X. Method and system for image segmentation. EP 2645329; 02/10/2013.
  • Papers in the research focus “cell dynamics and imaging”

    all papers by Xiaoyi Jiang

    2019

    Michels T, Berh D, Jiang X. An RJMCMC-Based Method for Tracking and Resolving Collisions of Drosophila Larvae. IEEE/ACM Trans Comput Biol Bioinform 2019;16: 465 - 474. Abstract

    2018

    Berh D, Scherzinger A, Otto N, Jiang X, Klambt C, Risse B. Automatic non-invasive heartbeat quantification of Drosophila pupae. Comput Biol Med 2018;93: 189-199. Abstract
    Frohwein LJ, Hess M, Schlicher D, Bolwin K, Büther F, Jiang X, Schäfers KP. PET attenuation correction for flexible MRI surface coils in hybrid PET/MRI using a 3D depth camera. Phys Med Biol 2018;63: 025033. Abstract
    Otto N, Marelja Z, Schoofs A, Kranenburg H, Bittern J, Yildirim K, Berh D, Bethke M, Thomas S, Rode S, Risse B, Jiang X, Pankratz M, Leimkuhler S, Klambt C. The sulfite oxidase Shopper controls neuronal activity by regulating glutamate homeostasis in Drosophila ensheathing glia. Nat Commun 2018;9: 3514. Abstract

    2017

    Almeida-Carvalho MJ, Berh D, Braun A, Chen Y-C, Eichler K, Eschbach C, Fritsch PMJ, Gerber B, Hoyer N, Jiang X, Kleber J, Klambt C, Konig C, Louis M, Michels B, Miroschnikow A, Mirth C, Miura D, Niewalda T, Otto N, Paisios E, Pankratz MJ, Petersen M, Ramsperger N, Randel N, Risse B, Saumweber T, Schlegel P, Schleyer M, Soba P, Sprecher SG, Tanimura T, Thum AS, Toshima N, Truman JW, Yarali A, Zlatic M. The Ol1mpiad: concordance of behavioural faculties of stage 1 and stage 3 Drosophila larvae. J Exp Biol 2017;220: 2452-2475. Abstract
    Berh D, Risse B, Michels T, Otto N, Jiang X, Klambt C. An FIM-Based Long-Term In-Vial Monitoring System for Drosophila Larvae. IEEE Trans. Biomed. Eng. 2017;64: 1862-1874. Abstract
    Bian A, Scherzinger A, Jiang X. An enhanced multi-label random walk for biomedical image segmentation using statistical seed generation. In: Blanc-Talon et al. (Eds.): ACIVS 2017, LNCS 10617 2017;Springer, Cham: 748–760. Abstract
    Hagerling R, Drees D, Scherzinger A, Dierkes C, Martin-Almedina S, Butz S, Gordon K, Schafers M, Hinrichs K, Ostergaard P, Vestweber D, Goerge T, Mansour S, Jiang X, Mortimer PS, Kiefer F. VIPAR, a quantitative approach to 3D histopathology applied to lymphatic malformations. JCI Insight 2017;2Abstract
    Risse B, Berh D, Otto N, Klambt C, Jiang X. FIMTrack: An open source tracking and locomotion analysis software for small animals. PLoS Comput Biol 2017;13: e1005530. Abstract
    Risse B, Otto N, Berh D, Jiang X, Kiel M, Klambt C. FIM2c : A Multi-Colour, Multi-Purpose Imaging System to Manipulate and Analyse Animal Behaviour. IEEE Trans Biomed Eng 2017;64: 610-620. Abstract
    Scherzinger A, Klemm S, Berh D, Jiang X. CNN-based background subtraction for long-term in-vial FIM imaging. In: Felsberg et al. (Eds.): Computer Analysis of Images and Patterns. CAIP 2017. LNCS 10424 2017;Springer, Cham: 359–371. Abstract
    Seifert R, Scherzinger A, Kiefer F, Hermann S, Jiang X, Schafers MA. Statistical Permutation-based Artery Mapping (SPAM): a novel approach to evaluate imaging signals in the vessel wall. BMC Med Imaging 2017;17: 36. Abstract

    2016

    Bian A, Jiang X. Statistical Modeling Based Adaptive Parameter Setting for Random Walk Segmentation. Lect Notes Comput Sc 2016;10016: 698-710. Abstract
    Otto N, Risse B, Berh D, Bittern J, Jiang X, Klambt C. Interactions among Drosophila larvae before and during collision. Sci Rep 2016;6: 31564. Abstract

    2015

    Jiang X, Percannella G, Vento M. A Verification-Based Multithreshold Probing Approach to HEp-2 Cell Segmentation. Lect Notes Comput Sc 2015;9257: 266-276. Abstract
    Risse B, Berh D, Otto N, Jiang X, Klambt C. Quantifying subtle locomotion phenotypes of Drosophila larvae using internal structures based on FIM images. Comput Biol Med 2015;63: 269-276. Abstract
    Schmid S, Jiang X, Schafers K. Puzzle Approach to Pose Tracking of a Rigid Object in a Multi Camera System. Lect Notes Comput Sc 2015;9256: 337-349. Abstract
    Seebach J, Taha AA, Lenk J, Lindemann N, Jiang X, Brinkmann K, Bogdan S, Schnittler H-J. The CellBorderTracker, a novel tool to quantitatively analyze spatiotemporal endothelial junction dynamics at the subcellular level. Histochem Cell Biol 2015;144: 517-532. Abstract
    Tenbrinck D, Jiang X. Image segmentation with arbitrary noise models by solving minimal surface problems. Pattern Recognition 2015;48: 3293-3309. Abstract
    Wu Z, Jiang X, Zheng N, Cheng D. Efficient block-wise temporally consistent contour,extraction in image sequences. Neurocomputing 2015;152: 127-138. Abstract
    Wu Z, Jiang X, Zheng N, Liu Y, Cheng D. Exact solution to median surface problem using 3D graph search and application to parameter space exploration. Pattern Recognition 2015;48: 380-390. Abstract

    2014

    Lammel U, Bechtold M, Risse B, Berh D, Fleige A, Bunse I, Jiang X, Klambt C, Bogdan S. The Drosophila FHOD1-like formin Knittrig acts through Rok to promote stress fiber formation and directed macrophage migration during the cellular immune response. Development 2014;141: 1366-1380. Abstract
    Risse B, Otto N, Berh D, Jiang X, Klambt C. FIM imaging and FIMtrack: two new tools allowing high-throughput and cost effective locomotion analysis. J Vis Exp 2014: e52207. Abstract
    Ungru K, Tenbrinck D, Jiang X, Stypmann J. Automatic classification of left ventricular wall segments in small animal ultrasound imaging. Comput Methods Programs Biomed 2014;117: 2-12. Abstract

    2013

    Dawood M, Gigengack F, Jiang X, Schäfers KP. A mass conservation-based optical flow method for cardiac motion correction in 3D-PET. Med Phys 2013;40: 012505. Abstract
    Fieseler M, Kugel H, Gigengack F, Kösters T, Büther F, Quick HH, Faber C, Jiang X, Schäfers KP. A dynamic thorax phantom for the assessment of cardiac and respiratory motion correction in PET/MRI: A preliminary evaluation. Nucl Instrum Methods Phys Res A 2013;702: 59-63. Abstract
    Gigengack F, Ruthotto L, Jiang X, Modersitzki J, Burger M, Hermann S, Schäfers KP. Atlas-Based Whole-Body PET-CT Segmentation using a Passive Contour Distance. Lect Notes Comput Sc 2013;7766: 82-92. Abstract
    Jiang X, Dawood M, Gigengack F, Risse B, Schmid S, Tenbrinck D, Schäfers K. Biomedical imaging: A computer vision perspective. Lect Notes Comput Sc 2013;8047: 1-19. Abstract
    Jiang X, Tenbrinck D. Region based contour detection by dynamic programming. Lect Notes Comput Sc 2013;8048: 152-159. Abstract
    Risse B, Thomas S, Otto N, Lopmeier T, Valkov D, Jiang X, Klambt C. FIM, a novel FTIR-based imaging method for high throughput locomotion analysis. PLoS One 2013;8: e53963. Abstract
    Sander M, Squarr AJ, Risse B, Jiang X, Bogdan S. Drosophila pupal macrophages--a versatile tool for combined ex vivo and in vivo imaging of actin dynamics at high resolution. Eur J Cell Biol 2013;92: 349-354. Abstract
    Sawatzky A, Tenbrinck D, Jiang X, Burger M. A Variational Framework for Region-Based Segmentation Incorporating Physical Noise Models. J Math Imaging Vision 2013;47(3): 179-209. Abstract
    Schmid S, Jiang X, Schäfers K. High-precision lens distortion correction using smoothed thin plate splines. Lect Notes Comput Sc 2013;8048: 432-439. Abstract
    Tenbrinck D, Jiang X. Discriminant Analysis based Level Set Segmentation for Ultrasound Imaging. Lect Notes Comput Sc 2013;8048: 144-151. Abstract
    Tenbrinck D, Schmid S, Jiang X, Schäfers K, Stypmann J. Histogram-based Optical Flow for Motion Estimation in Ultrasound Imaging. J Math Imaging Vision 2013;47(1): 138-150.