Participation in “Cells in Motion”

  • Project FF-2014-01: Molecular mechanisms controlling DC migration in CNS autoimmunity (Judith Alferink, Martin Bähler, project time: 07/2014 - 06/2016)
  • Papers in the research focus “cell dynamics and imaging”

    2019

    Ali S, Mann-Nuttel R, Schulze A, Richter L, Alferink J, Scheu S. Sources of Type I Interferons in Infectious Immunity: Plasmacytoid Dendritic Cells Not Always in the Driver's Seat. Front Immunol 2019;10: 778. Abstract
    Ambree O, Ruland C, Zwanzger P, Klotz L, Baune BT, Arolt V, Scheu S, Alferink J. Social Defeat Modulates T Helper Cell Percentages in Stress Susceptible and Resilient Mice. Int J Mol Sci 2019;20: E3512. Abstract
    Culmsee C, Michels S, Scheu S, Arolt V, Dannlowski U, Alferink J. Mitochondria, Microglia, and the Immune System-How Are They Linked in Affective Disorders?. Front Psychiatry 2019;9: 739. Abstract
    Howe M, Bauer J, Schulze A, Kropp S, Locksley RM, Alferink J, Weighardt H, Scheu S. Production of IFNbeta by Conventional Dendritic Cells after Stimulation with Viral Compounds and IFNbeta-Independent IFNAR1-Signaling Pathways are Associated with Aggravation of Polymicrobial Sepsis. Int J Mol Sci 2019;20: E4410. Abstract
    Scheu S, Ali S, Mann-Nuttel R, Richter L, Arolt V, Dannlowski U, Kuhlmann T, Klotz L, Alferink J. Interferon beta-Mediated Protective Functions of Microglia in Central Nervous System Autoimmunity. Int J Mol Sci 2019;20: E190. Abstract

    2018

    Ahmetspahic D, Schwarte K, Ambree O, Burger C, Falcone V, Seiler K, Kooybaran MR, Grosse L, Roos F, Scheffer J, Jorgens S, Koelkebeck K, Dannlowski U, Arolt V, Scheu S, Alferink J. Altered B Cell Homeostasis in Patients with Major Depressive Disorder and Normalization of CD5 Surface Expression on Regulatory B Cells in Treatment Responders. J Neuroimmune Pharmacol 2018;13: 90-99. Abstract
    Ali S, Hoven A, Dress RJ, Schaal H, Alferink J, Scheu S. Identification of a novel Dlg2 isoform differentially expressed in IFNbeta-producing plasmacytoid dendritic cells. BMC Genomics 2018;19: 194. Abstract
    Ambree O, Ruland C, Scheu S, Arolt V, Alferink J. Alterations of the Innate Immune System in Susceptibility and Resilience After Social Defeat Stress. Front Behav Neurosci 2018;12: 141. Abstract
    Fülle L, Offermann N, Hansen JN, Breithausen B, Erazo AB, Schanz O, Radau L, Gondorf F, Knopper K, Alferink J, Abdullah Z, Neumann H, Weighardt H, Henneberger C, Halle A, Forster I. CCL17 exerts a neuroimmune modulatory function and is expressed in hippocampal neurons. Glia 2018;66: 2246-2261. Abstract
    Kovac S, Alferink J, Ahmetspahic D, Arolt V, Melzer N. [Update on anti-N-methyl-D-aspartate receptor encephalitis]. Nervenarzt 2018;89: 99-112. Abstract

    2017

    Buerger C, Redlich R, Grotegerd D, Meinert S, Dohm K, Schneider I, Zaremba D, Forster K, Alferink J, Bolte J, Heindel W, Kugel H, Arolt V, Dannlowski U. Differential Abnormal Pattern of Anterior Cingulate Gyrus Activation in Unipolar and Bipolar Depression: an fMRI and Pattern Classification Approach. Neuropsychopharmacology 2017;42: 1399-1408. Abstract
    Koelkebeck K, Liedtke C, Kohl W, Alferink J, Kret ME. Attachment style moderates theory of mind abilities in depression. J Affect Disord 2017;213: 156-160. Abstract
    Opel N, Redlich R, Grotegerd D, Dohm K, Zaremba D, Meinert S, Burger C, Plumpe L, Alferink J, Heindel W, Kugel H, Zwanzger P, Arolt V, Dannlowski U. Prefrontal brain responsiveness to negative stimuli distinguishes familial risk for major depression from acute disorder. J Psychiatry Neurosci 2017;42: 160198. Abstract
    Redlich R, Burger C, Dohm K, Grotegerd D, Opel N, Zaremba D, Meinert S, Forster K, Repple J, Schnelle R, Wagenknecht C, Zavorotnyy M, Heindel W, Kugel H, Gerbaulet M, Alferink J, Arolt V, Zwanzger P, Dannlowski U. Effects of electroconvulsive therapy on amygdala function in major depression - a longitudinal functional magnetic resonance imaging study. Psychol Med 2017: 1-11. Abstract
    Ruland C, Renken H, Kuzmanov I, Fattahi Mehr A, Schwarte K, Cerina M, Herrmann A, Otte D-M, Zimmer A, Schwab N, Meuth SG, Arolt V, Klotz L, Forster I, Scheu S, Alferink J. Chemokine CCL17 is expressed by dendritic cells in the CNS during experimental autoimmune encephalomyelitis and promotes pathogenesis of disease. Brain Behav Immun 2017;66: 382-393. Abstract
    Scheu S, Ali S, Ruland C, Arolt V, Alferink J. The C-C Chemokines CCL17 and CCL22 and Their Receptor CCR4 in CNS Autoimmunity. Int J Mol Sci 2017;18Abstract

    2016

    Alferink J, Specht S, Arends H, Schumak B, Schmidt K, Ruland C, Lundt R, Kemter A, Dlugos A, Kuepper JM, Poppensieker K, Findeiss M, Albayram O, Otte D-M, Marazzi J, Gertsch J, Forster I, Maier W, Scheu S, Hoerauf A, Zimmer A. Cannabinoid Receptor 2 Modulates Susceptibility to Experimental Cerebral Malaria through a CCL17-dependent Mechanism. J Biol Chem 2016;291: 19517-19531. Abstract
    Ambree O, Bergink V, Grosse L, Alferink J, Drexhage HA, Rothermundt M, Arolt V, Birkenhager TK. S100B Serum Levels Predict Treatment Response in Patients with Melancholic Depression. Int J Neuropsychopharmacol 2016;19: pyv103. Abstract
    Ambree O, Klassen I, Forster I, Arolt V, Scheu S, Alferink J. Reduced locomotor activity and exploratory behavior in CC chemokine receptor 4 deficient mice. Behav Brain Res 2016;314: 87-95. Abstract
    Bauer J, Dress RJ, Schulze A, Dresing P, Ali S, Deenen R, Alferink J, Scheu S. Cutting Edge: IFN-beta Expression in the Spleen Is Restricted to a Subpopulation of Plasmacytoid Dendritic Cells Exhibiting a Specific Immune Modulatory Transcriptome Signature. J Immunol 2016;196: 4447-4451. Abstract
    Gross CC, Ahmetspahic D, Ruck T, Schulte-Mecklenbeck A, Schwarte K, Jorgens S, Scheu S, Windhagen S, Graefe B, Melzer N, Klotz L, Arolt V, Wiendl H, Meuth SG, Alferink J. Alemtuzumab treatment alters circulating innate immune cells in multiple sclerosis. Neurol Neuroimmunol Neuroinflamm 2016;3: e289. Abstract
    Redlich R, Opel N, Grotegerd D, Dohm K, Zaremba D, Burger C, Munker S, Muhlmann L, Wahl P, Heindel W, Arolt V, Alferink J, Zwanzger P, Zavorotnyy M, Kugel H, Dannlowski U. Prediction of Individual Response to Electroconvulsive Therapy via Machine Learning on Structural Magnetic Resonance Imaging Data. JAMA Psychiatry 2016;73: 557-564. Abstract

    2015

    Grosse L, Carvalho LA, Wijkhuijs AJM, Bellingrath S, Ruland T, Ambree O, Alferink J, Ehring T, Drexhage HA, Arolt V. Clinical characteristics of inflammation-associated depression: Monocyte gene expression is age-related in major depressive disorder. Brain Behav Immun 2015;44: 48-56. Abstract
    Kemter AM, Scheu S, Huser N, Ruland C, Schumak B, Findeiss M, Cheng Z, Assfalg V, Arolt V, Zimmer A, Alferink J. The cannabinoid receptor 2 is involved in acute rejection of cardiac allografts. Life Sci 2015;138: 29-34. Abstract
    Kocur M, Schneider R, Pulm A-K, Bauer J, Kropp S, Gliem M, Ingwersen J, Goebels N, Alferink J, Prozorovski T, Aktas O, Scheu S. IFNbeta secreted by microglia mediates clearance of myelin debris in CNS autoimmunity. Acta Neuropathol Commun 2015;3: 20. Abstract
    Schmole A-C, Lundt R, Ternes S, Albayram O, Ulas T, Schultze JL, Bano D, Nicotera P, Alferink J, Zimmer A. Cannabinoid receptor 2 deficiency results in reduced neuroinflammation in an Alzheimer's disease mouse model. Neurobiol Aging 2015;36: 710-719. Abstract

    2014

    Duerr GD, Heinemann JC, Suchan G, Kolobara E, Wenzel D, Geisen C, Matthey M, Passe-Tietjen K, Mahmud W, Ghanem A, Tiemann K, Alferink J, Burgdorf S, Buchalla R, Zimmer A, Lutz B, Welz A, Fleischmann BK, Dewald O. The endocannabinoid-CB2 receptor axis protects the ischemic heart at the early stage of cardiomyopathy. Basic Res Cardiol 2014;109: 425. Abstract
    Globisch T, Steiner N, Fulle L, Lukacs-Kornek V, Degrandi D, Dresing P, Alferink J, Lang R, Pfeffer K, Beyer M, Weighardt H, Kurts C, Ulas T, Schultze JL, Forster I. Cytokine-dependent regulation of dendritic cell differentiation in the splenic microenvironment. Eur J Immunol 2014;44: 500-510. Abstract