Beteiligung am Exzellenzcluster

CiM-Gruppenleiterin

  • Forschungsgebiet A.4: Monitoring molekularer Mechanismen der Monozytenmigration in entzündlichen Prozessen in vivo
  • Projekt FF-2014-01: Molekulare Kontrollmechanismen der Migration von dendritischen Zellen in der ZNS Autoimmunität (Judith Alferink, Martin Bähler, Projektlaufzeit: 07/2014 - 06/2016)

CiM-Publikationen

2018

Ahmetspahic D, Schwarte K, Ambree O, Burger C, Falcone V, Seiler K, Kooybaran MR, Grosse L, Roos F, Scheffer J, Jorgens S, Koelkebeck K, Dannlowski U, Arolt V, Scheu S, Alferink J. Altered B Cell Homeostasis in Patients with Major Depressive Disorder and Normalization of CD5 Surface Expression on Regulatory B Cells in Treatment Responders. J Neuroimmune Pharmacol 2018;13: 90-99. Abstract
Ali S, Hoven A, Dress RJ, Schaal H, Alferink J, Scheu S. Identification of a novel Dlg2 isoform differentially expressed in IFNbeta-producing plasmacytoid dendritic cells. BMC Genomics 2018;19: 194. Abstract
Kovac S, Alferink J, Ahmetspahic D, Arolt V, Melzer N. [Update on anti-N-methyl-D-aspartate receptor encephalitis]. Nervenarzt 2018;89: 99-112. Abstract

2017

Buerger C, Redlich R, Grotegerd D, Meinert S, Dohm K, Schneider I, Zaremba D, Forster K, Alferink J, Bolte J, Heindel W, Kugel H, Arolt V, Dannlowski U. Differential Abnormal Pattern of Anterior Cingulate Gyrus Activation in Unipolar and Bipolar Depression: an fMRI and Pattern Classification Approach. Neuropsychopharmacology 2017;42: 1399-1408. Abstract
Koelkebeck K, Liedtke C, Kohl W, Alferink J, Kret ME. Attachment style moderates theory of mind abilities in depression. J Affect Disord 2017;213: 156-160. Abstract
Opel N, Redlich R, Grotegerd D, Dohm K, Zaremba D, Meinert S, Burger C, Plumpe L, Alferink J, Heindel W, Kugel H, Zwanzger P, Arolt V, Dannlowski U. Prefrontal brain responsiveness to negative stimuli distinguishes familial risk for major depression from acute disorder. J Psychiatry Neurosci 2017;42: 160198. Abstract
Redlich R, Burger C, Dohm K, Grotegerd D, Opel N, Zaremba D, Meinert S, Forster K, Repple J, Schnelle R, Wagenknecht C, Zavorotnyy M, Heindel W, Kugel H, Gerbaulet M, Alferink J, Arolt V, Zwanzger P, Dannlowski U. Effects of electroconvulsive therapy on amygdala function in major depression - a longitudinal functional magnetic resonance imaging study. Psychol Med 2017: 1-11. Abstract
Ruland C, Renken H, Kuzmanov I, Fattahi Mehr A, Schwarte K, Cerina M, Herrmann A, Otte D-M, Zimmer A, Schwab N, Meuth SG, Arolt V, Klotz L, Forster I, Scheu S, Alferink J. Chemokine CCL17 is expressed by dendritic cells in the CNS during experimental autoimmune encephalomyelitis and promotes pathogenesis of disease. Brain Behav Immun 2017;66: 382-393. Abstract
Scheu S, Ali S, Ruland C, Arolt V, Alferink J. The C-C Chemokines CCL17 and CCL22 and Their Receptor CCR4 in CNS Autoimmunity. Int J Mol Sci 2017;18Abstract

2016

Alferink J, Specht S, Arends H, Schumak B, Schmidt K, Ruland C, Lundt R, Kemter A, Dlugos A, Kuepper JM, Poppensieker K, Findeiss M, Albayram O, Otte D-M, Marazzi J, Gertsch J, Forster I, Maier W, Scheu S, Hoerauf A, Zimmer A. Cannabinoid Receptor 2 Modulates Susceptibility to Experimental Cerebral Malaria through a CCL17-dependent Mechanism. J Biol Chem 2016;291: 19517-19531. Abstract
Ambree O, Bergink V, Grosse L, Alferink J, Drexhage HA, Rothermundt M, Arolt V, Birkenhager TK. S100B Serum Levels Predict Treatment Response in Patients with Melancholic Depression. Int J Neuropsychopharmacol 2016;19: pyv103. Abstract
Ambree O, Klassen I, Forster I, Arolt V, Scheu S, Alferink J. Reduced locomotor activity and exploratory behavior in CC chemokine receptor 4 deficient mice. Behav Brain Res 2016;314: 87-95. Abstract
Bauer J, Dress RJ, Schulze A, Dresing P, Ali S, Deenen R, Alferink J, Scheu S. Cutting Edge: IFN-beta Expression in the Spleen Is Restricted to a Subpopulation of Plasmacytoid Dendritic Cells Exhibiting a Specific Immune Modulatory Transcriptome Signature. J Immunol 2016;196: 4447-4451. Abstract
Gross CC, Ahmetspahic D, Ruck T, Schulte-Mecklenbeck A, Schwarte K, Jorgens S, Scheu S, Windhagen S, Graefe B, Melzer N, Klotz L, Arolt V, Wiendl H, Meuth SG, Alferink J. Alemtuzumab treatment alters circulating innate immune cells in multiple sclerosis. Neurol Neuroimmunol Neuroinflamm 2016;3: e289. Abstract
Redlich R, Opel N, Grotegerd D, Dohm K, Zaremba D, Burger C, Munker S, Muhlmann L, Wahl P, Heindel W, Arolt V, Alferink J, Zwanzger P, Zavorotnyy M, Kugel H, Dannlowski U. Prediction of Individual Response to Electroconvulsive Therapy via Machine Learning on Structural Magnetic Resonance Imaging Data. JAMA Psychiatry 2016;73: 557-564. Abstract

2015

Grosse L, Carvalho LA, Wijkhuijs AJM, Bellingrath S, Ruland T, Ambree O, Alferink J, Ehring T, Drexhage HA, Arolt V. Clinical characteristics of inflammation-associated depression: Monocyte gene expression is age-related in major depressive disorder. Brain Behav Immun 2015;44: 48-56. Abstract
Kemter AM, Scheu S, Huser N, Ruland C, Schumak B, Findeiss M, Cheng Z, Assfalg V, Arolt V, Zimmer A, Alferink J. The cannabinoid receptor 2 is involved in acute rejection of cardiac allografts. Life Sci 2015;138: 29-34. Abstract
Kocur M, Schneider R, Pulm A-K, Bauer J, Kropp S, Gliem M, Ingwersen J, Goebels N, Alferink J, Prozorovski T, Aktas O, Scheu S. IFNbeta secreted by microglia mediates clearance of myelin debris in CNS autoimmunity. Acta Neuropathol Commun 2015;3: 20. Abstract
Schmole A-C, Lundt R, Ternes S, Albayram O, Ulas T, Schultze JL, Bano D, Nicotera P, Alferink J, Zimmer A. Cannabinoid receptor 2 deficiency results in reduced neuroinflammation in an Alzheimer's disease mouse model. Neurobiol Aging 2015;36: 710-719. Abstract

2014

Duerr GD, Heinemann JC, Suchan G, Kolobara E, Wenzel D, Geisen C, Matthey M, Passe-Tietjen K, Mahmud W, Ghanem A, Tiemann K, Alferink J, Burgdorf S, Buchalla R, Zimmer A, Lutz B, Welz A, Fleischmann BK, Dewald O. The endocannabinoid-CB2 receptor axis protects the ischemic heart at the early stage of cardiomyopathy. Basic Res Cardiol 2014;109: 425. Abstract
Globisch T, Steiner N, Fulle L, Lukacs-Kornek V, Degrandi D, Dresing P, Alferink J, Lang R, Pfeffer K, Beyer M, Weighardt H, Kurts C, Ulas T, Schultze JL, Forster I. Cytokine-dependent regulation of dendritic cell differentiation in the splenic microenvironment. Eur J Immunol 2014;44: 500-510. Abstract