Beteiligung an „Cells in Motion“

  • Cells-in-Motion-Professor für Zellmechanik
  • Mitglied im Graduiertenprogramm CiM-IMPRS
  • Mitglied im Imaging Network – Mikroskopie
  • Forschungsinteressen: cell mechanics, cell motility, cancer cell invasion, 3D organoid and tumour models, zebrafish development, soft matter physics, microscopy development, optical tweezers and UV microablation, traction force microscopy, non-equilibrium physics in living systems, mechanics of transmigration, actin based force generation, quantitative modelling of active living systems
  • Projekt FF-2015-01 – Mechanische Anpassung wandernder Zellen im Kontext von Immunantwort und embyonaler Entwicklung (Timo Betz, Projektlaufzeit: 07/2015 - 06/2017)

  • Publikationen im Forschungsschwerpunkt „Zelldynamik und Bildgebung“

    alle Publikationen von Timo Betz

    2018

    Ahmed WW, Fodor E, Almonacid M, Bussonnier M, Verlhac M-H, Gov N, Visco P, van Wijland F, Betz T. Active Mechanics Reveal Molecular-Scale Force Kinetics in Living Oocytes. Biophys J 2018;114: 1667-1679. Abstract
    Wallmeyer B, Trinschek S, Yigit S, Thiele U, Betz T. Collective Cell Migration in Embryogenesis Follows the Laws of Wetting. Biophys J 2018;114: 213-222. Abstract

    2017

    Attieh Y, Clark AG, Grass C, Richon S, Pocard M, Mariani P, Elkhatib N, Betz T, Gurchenkov B, Vignjevic DM. Cancer-associated fibroblasts lead tumor invasion through integrin-beta3-dependent fibronectin assembly. J Cell Biol 2017;216: 3509-3520. Abstract
    Goudarzi M, Tarbashevich K, Mildner K, Begemann I, Garcia J, Paksa A, Reichman-Fried M, Mahabaleshwar H, Blaser H, Hartwig J, Zeuschner D, Galic M, Bagnat M, Betz T, Raz E. Bleb Expansion in Migrating Cells Depends on Supply of Membrane from Cell Surface Invaginations. Dev Cell 2017;43: 577-587.e5. Abstract
    Horner F, Meissner R, Polali S, Pfeiffer J, Betz T, Denz C, Raz E. Holographic optical tweezers-based in vivo manipulations in zebrafish embryos. J Biophotonics 2017;10: 1492-1501. Abstract
    Peuhu E, Kaukonen R, Lerche M, Saari M, Guzmán C, Rantakari P, De Franceschi N, Wärri A, Georgiadou M, Jacquemet G, Mattila E, Virtakoivu R, Liu Y, Attie Y, Silva K, Betz T, Sundberg J, Salmi M, Deugnier MA, Eliceiri K, Ivaska J. SHARPIN regulates collagen architecture and ductal outgrowth in the developing mouse mammary gland. EMBO J 2017;36: 165-182. Abstract

    2016

    Caorsi V, Lemiere J, Campillo C, Bussonnier M, Manzi J, Betz T, Plastino J, Carvalho K, Sykes C. Cell-sized liposome doublets reveal active tension build-up driven by acto-myosin dynamics. Soft Matter 2016;12: 6223-6231. Abstract
    Kaukonen R, Mai A, Georgiadou M, Saari M, De Franceschi N, Betz T, Sihto H, Ventela S, Elo L, Jokitalo E, Westermarck J, Kellokumpu-Lehtinen P-L, Joensuu H, Grenman R, Ivaska J. Normal stroma suppresses cancer cell proliferation via mechanosensitive regulation of JMJD1a-mediated transcription. Nat Commun 2016;7: 12237. Abstract
    Kopanska KS, Alcheikh Y, Staneva R, Vignjevic D, Betz T, Engler AJ. Tensile Forces Originating from Cancer Spheroids Facilitate Tumor Invasion. PLoS ONE 2016;11: e0156442. Abstract
    Turlier H, Fedosov DA, Audoly B, Auth T, Gov NS, Sykes C, Joanny J-F, Gompper G, Betz T. Equilibrium physics breakdown reveals the active nature of red blood cell flickering. Nat Phys 2016;12: 513-519. Abstract
    Valentino F, Sens P, Lemiere J, Allard A, Betz T, Campillo C, Sykes C. Fluctuations of a membrane nanotube revealed by high-resolution force measurements. Soft Matter 2016;12: 9429-9435. Abstract

    2015

    Garate F, Betz T, Pertusa M, Bernal R. Time-resolved neurite mechanics by thermal fluctuation assessments. Phys Biol 2015;12: 066020. Abstract