Participation in the Cluster of Excellence

CiM Professor of Cell Mechanics
CiM-IMPRS Graduate School Member

  • Research Area A.1: Cellular Polarization and Changes in Cell Shape
  • Research Area A.3: Functional Membrane Domains in Neuronal and Non-Neuronal Compartmentalization
  • Research Area A.6: Motion Analysis in Cellular Systems
  • Research Area B.2: Regulation of Vascular Permeability and Leukocyte Extravasation
  • Project FF-2015-01 – Mechanical adaptation of motile cells in development and immune response (Timo Betz, project time: 07/2015 - 06/2017)
© CiM - Peter Grewer

“The birth of my children made me realize how relevant our experiments are.“

Dr. Timo Betz is a physicist – and feels absolutely at home in the field of biology. After all, as a biophysicist he is the embodiment of an interface between the two fields. He undertakes research into the mechanics of cells, looking for the easiest possible answers. Read the interview

CiM Papers

all papers by Timo Betz


Ahmed WW, Fodor E, Almonacid M, Bussonnier M, Verlhac M-H, Gov NS, Visco P, Wijland F van, Betz T. Active mechanics reveal molecular-scale force kinetics in living oocytes. arXiv 2018: epub. Abstract
Wallmeyer B, Trinschek S, Yigit S, Thiele U, Betz T. Collective Cell Migration in Embryogenesis Follows the Laws of Wetting. Biophys J 2018;114: 213-222. Abstract


Attieh Y, Clark AG, Grass C, Richon S, Pocard M, Mariani P, Elkhatib N, Betz T, Gurchenkov B, Vignjevic DM. Cancer-associated fibroblasts lead tumor invasion through integrin-beta3-dependent fibronectin assembly. J Cell Biol 2017;216: 3509-3520. Abstract
Goudarzi M, Tarbashevich K, Mildner K, Begemann I, Garcia J, Paksa A, Reichman-Fried M, Mahabaleshwar H, Blaser H, Hartwig J, Zeuschner D, Galic M, Bagnat M, Betz T, Raz E. Bleb Expansion in Migrating Cells Depends on Supply of Membrane from Cell Surface Invaginations. Dev Cell 2017;43: 577-587.e5. Abstract
Horner F, Meissner R, Polali S, Pfeiffer J, Betz T, Denz C, Raz E. Holographic optical tweezers-based in vivo manipulations in zebrafish embryos. J Biophotonics 2017;10: 1492-1501. Abstract
Peuhu E, Kaukonen R, Lerche M, Saari M, Guzmán C, Rantakari P, De Franceschi N, Wärri A, Georgiadou M, Jacquemet G, Mattila E, Virtakoivu R, Liu Y, Attie Y, Silva K, Betz T, Sundberg J, Salmi M, Deugnier MA, Eliceiri K, Ivaska J. SHARPIN regulates collagen architecture and ductal outgrowth in the developing mouse mammary gland. EMBO J 2017;36: 165-182. Abstract


Caorsi V, Lemiere J, Campillo C, Bussonnier M, Manzi J, Betz T, Plastino J, Carvalho K, Sykes C. Cell-sized liposome doublets reveal active tension build-up driven by acto-myosin dynamics. Soft Matter 2016;12: 6223-6231. Abstract
Kaukonen R, Mai A, Georgiadou M, Saari M, De Franceschi N, Betz T, Sihto H, Ventela S, Elo L, Jokitalo E, Westermarck J, Kellokumpu-Lehtinen P-L, Joensuu H, Grenman R, Ivaska J. Normal stroma suppresses cancer cell proliferation via mechanosensitive regulation of JMJD1a-mediated transcription. Nat Commun 2016;7: 12237. Abstract
Kopanska KS, Alcheikh Y, Staneva R, Vignjevic D, Betz T, Engler AJ. Tensile Forces Originating from Cancer Spheroids Facilitate Tumor Invasion. PLoS ONE 2016;11: e0156442. Abstract
Turlier H, Fedosov DA, Audoly B, Auth T, Gov NS, Sykes C, Joanny J-F, Gompper G, Betz T. Equilibrium physics breakdown reveals the active nature of red blood cell flickering. Nat Phys 2016;12: 513-519. Abstract
Valentino F, Sens P, Lemiere J, Allard A, Betz T, Campillo C, Sykes C. Fluctuations of a membrane nanotube revealed by high-resolution force measurements. Soft Matter 2016;12: 9429-9435. Abstract


Garate F, Betz T, Pertusa M, Bernal R. Time-resolved neurite mechanics by thermal fluctuation assessments. Phys Biol 2015;12: 066020. Abstract