© Helene Richter

Prof. Dr. helene richter

richterh@uni-muenster.de

Tel: (+49)-(0)251-83-21014
Fax: (+49)-(0)251-83-23896

Room 152

Office hours: upon consultation

 
  • Research Areas

    • Animal welfare
    • Cognition and emotion
    • Refinement of animal experiments and housing conditions
    • Reproducibility and generalizability of animal experiments
    • Animal welfare and animal personality
  • CV

    Education

    -
    PhD-studies, Animal Welfare and Ethology, Justus-Liebig-Universität Gießen
    -
    Studies of Biology, Westfälische Wilhelms-Universität Münster

    Positions

    since
    Professor for Behavioural Biology and Animal Welfare
    -
    Postdoctoral researcher, Department of Behavioural Biology, Westfälische Wilhelms-Universität Münster
    -
    Postdoctoral researcher, Animal Models in Psychiatry, Central Institute of Mental Health and Bernstein Center for Computational Neuroscience (BCCN), Mannheim / Heidelberg
    -
    Postdoctoral researcher, Animal Welfare and Ethology, Veterinary Medicine, Justus-Liebig-Universität Gießen
    -
    PhD student, Animal Welfare and Ethology, Veterinary Medicine, Justus-Liebig-Universität Gießen

    Honors

    Aufnahme in das Margarete von Wrangell-Habilitationsprogramm 2014 - Ministerium für Wissenschaft, Forschung und Kunst Baden-Württemberg
    Klaus Tschira Preis für verständliche Wissenschaft 2011 (1. Platz für das Fach Biologie) - Klaus Tschira Stiftung gGmbH

    External functions

    since
    Member – CRC TRR 212 “A Novel Synthesis of Individualisation across Behaviour, Ecology and Evolution: Niche Choice, Niche Conformance, Niche Construction (NC3) (Steering Committee)
    -
    Stellvertretende Sprecherin – Executive board member of the Otto Creutzfeldt Center for Cognitive and Behavioral Neuroscience (OCC), Westfälische Wilhelms-Universität, Münster
    since
    Member of the Animal Welfare Committee (“Tierschutzausschuss”), University of Münster
    since
    Manager of the Ethological Society e.V.
    since
    Member of the Coordination Commission for Animal Experimentation, University of Münster
    -
    Member of the Hessian Animal Welfare Committee
    since
    Member of the Human Affectome Project, Neuroqualia, Happiness Team, Nova Scotia, Canada
    -
    Member of the Young North Rhine-Westphalian Academy of Sciences, Humanities and the Arts (“Junges Kolleg” NRW)
    since
    Member of the Ethological Society e.V.
    since
    Member of International Society of Applied Ethology (ISAE)

    Appointments

    Ruf auf eine Professur für "In vitro und in vivo Modelle" (§ 98 UG 2002), Veterinärmedizinische Universität Wien
    Ruf auf eine Professur für Verhaltensbiologie und Tierschutz (W2), Westfälische Wilhelms-Universität Münster
    Call for a temporary W2-S-professorship for “Animal welfare and refinement in animal experimentation”, Freie Universität Berlin and German Federal Institute for Risk Assessment (BfR)
    Call for a W1-professorship for “Ethology of Farm Animals”, Landwirtschaftliche Fakultät, Rheinische-Friedrich-Wilhelms Universität Bonn
  • Projects

    in process
    • NC3 - CRC 212 - A Novel Synthesis of Individualisation across Behaviour, Ecology and Evolution: Niche Choice, Niche Conformance, Niche Construction ( - )
      Main DFG-project hosted outside WWU: DFG - Collaborative Research Centre | Project Number: TRR 212/2
    • 3T: Animal Protection, Animal Welfare, Animal Ethics ( - )
      Own resources project: WWU-intern - Topical Programs
    • Weidebilder - Kunst in der Ambivalenz der Mensch-Tier-Beziehung ( - )
      Individual project: Bezirksregierung Münster | Project Number: 48.07.16-15/20 RKP
    • RTG 2220 EvoPAD - RTG 2220 - Evolutionary Processes in Adaptation and Disease ( - )
      Main DFG-project hosted at WWU: DFG - Research Training Group | Project Number: GRK 2220/1
    • Standardisierung, Heterogenisierung und Reproduzierbarkeit von Ergebnissen aus Tierversuchen ( - )
      Individual project: DFG - Individual Grants Programme | Project Number: RI 2488/3-1
    finished
    • The Individual in the Focus of Life Sciences ( - )
      Own resources project: WWU-intern - Topical Programs
    • NC3 - CRC 212 - A Novel Synthesis of Individualisation across Behaviour, Ecology and Evolution: Niche Choice, Niche Conformance, Niche Construction ( - )
      Main DFG-project hosted outside WWU: DFG - Collaborative Research Centre | Project Number: TRR 212/1
    • CRC TRR 212 A02 - Optimistic and pessimistic decision making under ambiguity: causes and consequences for niche choice and niche conformance ( - )
      Subproject in DFG-joint project hosted outside WWU: DFG - Collaborative Research Centre | Project Number: TRR 212/1
    • CRC TRR 58 - A01: Life history, serotonin transporter genotype and anxiety-like behaviour: testing the "coping-with-challenge hypothesis" ( - )
      Subproject in DFG-joint project hosted at WWU: DFG - Collaborative Research Centre | Project Number: TRR 58/4
  • Publications

    • Stieger B, Palme R, Kaiser S, Sachser N, Richter SH. . ‘When left is right: The effects of paw preference training on behaviour in mice.’ Behavioural Brain Research 430, No. 113929.
    • Von Kortzfleisch VT, Ambrée O, Karp NA, Meyer N, Novak J, Palme R, Rosso M, Touma C, Würbel H, Kaiser S, Sachser N, Richter SH. . ‘Do multiple experimenters improve the reproducibility of animal studies?PLoS Biology 20(3), No. e3001564. doi: 10.1371/journal.pbio.3001564.
    • Kaiser S, Richter SH. . „Don’t worry, be happy? Ein verhaltensbiologischer Blick auf das Gefühlsleben der Tiere.“ In Das unterschätzte Tier, herausgegeben von Sachser N, Kästner N, Zimmermann T, 33-48. Hamburg: Rowohlt Taschenbuch Verlag.
    • Rystrom TL, Prawitt RC, Richter SH, Sachser N, Kaiser S. . ‘Repeatability of endocrine traits and dominance rank in female guinea pigs.’ Frontiers in Zoology 19, No. 1: 4. doi: 10.1186/s12983-021-00449-2.
    • Feige-Diller J, Herrera-Rivero M, Witten A, Stoll M, Kaiser S, Richter SH, Sachser N. . ‘The impact of varying food availability on gene expression in the liver: Testing the Match-Mismatch hypothesis.Frontiers in Nutrition 9, No. 910762.
    • Bračić M, Bohn L, Siewert V, von Kortzfleisch V, Schielzeth H, Kaiser S, Sachser N, Richter SH. . ‘Once an Optimist, Always an Optimist? Studying Cognitive Judgment Bias in Mice.’ Behavioral Ecology 33: 775-788.

    • Feige-Diller J, Palme R, Kaiser S, Sachser N, Richter SH. . ‘The impact of varying food availability on health and welfare in mice: Testing the Match-Mismatch hypothesis.’ Physiology and Behavior 228, No. 113193. doi: 10.1016/j.physbeh.2020.113193.
    • Mutwill AM, Schielzeth H, Zimmermann TD, Richter SH, Kaiser S, Sachser N. . ‘Individuality meets plasticity: Endocrine phenotypes across male dominance rank acquisition in guinea pigs living in a complex social environment.’ Hormones and Behavior 131, No. 104967. doi: 10.1016/j.yhbeh.2021.104967.
    • Desjardins E, Kurtz J, Kranke N, Lindeza A, Richter SH. . ‘Beyond standardization: Improving external validity and reproducibility in experimental evolution.’ BioScience biab008. doi: 10.1093/biosci/biab008.
    • Stieger B, Melotti L, Quante SM, Kaiser S, Sachser N, Richter SH. . ‘A step in the right direction: the effect of context, strain and sex on paw preference in mice.’ Animal Behaviour 174: 21-30. doi: 10.1016/j.anbehav.2021.01.012.
    • Krakenberg V, Wewer M, Palme R, Kaiser S, Sachser N, Richter SH. . ‘Regular touchscreen training affects faecal corticosterone metabolites and anxiety-like behaviour in mice.’ Behavioural Brain Research 401: 113080. doi: 10.1016/j.bbr.2020.113080.
    • Bodden C, Wewer M, Kästner N, Palme R, Kaiser S, Sachser N, Richter SH. . ‘Not all mice are alike: Mixed-strain housing alters social behaviour.’ Physiology and Behavior 228, No. 113220. doi: 10.1016/j.physbeh.2020.113220.
    • Alexander R, Aragon OR, Bookwala J, Cherbuin N, Gatt JM, Kahrilas IJ, Kästner N, Lawrence A, Lowe L, Morrison RG, Mueller SC, Nusslock R, Papadelis C, Polnaszek KL, Richter SH, Silton RL, Styliadis C. . ‘The neuroscience of positive emotions and affect: Implications for cultivating happiness and wellbeing.Neuroscience and Biobehavioral Reviews 121: 220-249. doi: 10.1016/j.neubiorev.2020.12.002.
    • Melotti L, Siestrup S, Peng M, Vitali V, Dowling D, von Kortzfleisch VT, Bracic M, Sachser N, Kaiser S, Richter SH. . ‘Individuality, as well as genetic background, affects syntactical features of courtship songs in male mice.’ Animal Behaviour 180: 179-196.

    • Richter SH. . „Reproduzierbarkeit von Verhaltensdaten (Kapitel 8.3).“ In Methoden der Verhaltensbiologie, herausgegeben von Naguib M, Krause ET, 102-106. 2nd Ed. Berlin: Springer Spektrum.
    • Richter SH. . ‘Automated home-cage testing as a tool to improve reproducibility of behavioral research?Frontiers in Neuroscience 14: 383.
    • Feige-Diller J, Krakenberg V, Bierbaum L, Seifert L, Palme R, Kaiser S, Sachser N, Richter SH. . ‘The effects of different feeding routines on welfare in laboratory mice.’ Frontiers in Veterinary Science 6: 479.
    • Von Kortzfleisch VT, Karp NA, Palme R, Kaiser S, Sachser N, Richter SH. . ‘Improving reproducibility in animal research by splitting the study population into several ‘mini-experiments’.’ Scientific Reports 10, No. 16579. doi: 10.1038/s41598-020-73503-4.
    • Krakenberg V, Siestrup S, Palme R, Kaiser S, Sachser N, Richter SH. . ‘Effects of different social experiences on emotional state in mice.’ Scientific Reports 10, No. 15255. doi: 10.1038/s41598-020-71994-9.
    • Richter SH, von Kortzfleisch V. . ‘It is time for an empirically informed paradigm shift in animal research.’ Nature Reviews Neuroscience 21: 660. doi: 10.1038/s41583-020-0370-7.
    • Mutwill AM, Zimmermann TD, Hennicke A, Richter SH, Kaiser S, Sachser N. . ‘Adaptive reshaping of the hormonal phenotype after social niche transition in adulthood.’ Proceedings of the Royal Society B: Biological Sciences 287. doi: 10.1098/rspb.2020.0667.

    • Mutwill AM, Zimmermann TD, Reuland C, Fuchs S, Kunert J, Richter SH, Kaiser S, Sachser N. . ‘High reproductive success despite queuing – Socio-sexual development of males in a complex social environment.’ Frontiers in Psychology 10: 2810.
    • Krakenberg V, von Kortzfleisch V, Kaiser S, Sachser N, Richter SH. . ‘Differential effects of serotonin transporter genotype on anxiety-like behavior and cognitive judgment bias in mice.’ Frontiers in Behavioral Neuroscience 13: 263.
    • Haaker J, Maren S, Andreatta M, Merz CJ, Richter J, Richter SH, Drexler Shira S, Lange MD, Jüngling K, Nees F, Seidenbecher T, Fullana MA, Wotjak C, Lonsdorf TB. . ‘Making translation work: Harmonizing cross-species methodology in the behavioural neuroscience of Pavlovian fear conditioning.’ Neuroscience & Biobehavioral Reviews 107: 329-345.
    • Bodden C, von Kortzfleisch V, Karwinkel F, Kaiser S, Sachser N, Richter SH. . ‘Heterogenising study samples across testing time improves reproducibility of behavioural data.’ Scientific Reports 9: 8247.
    • Von Kortzfleisch V, Kästner N, Prange L, Kaiser S, Sachser N, Richter SH. . ‘Have I been here before? Effects of repeated testing and age on the results of behavioural tests.’ Behavioural Brain Research 367: 143-148.
    • Melotti L, Kästner N, Eick AK, Schnelle AL, Palme R, Sachser N, Kaiser S, Richter SH. . ‘Can live with ‘em, can live without ‘em: pair housed male C57BL/6J mice show low aggression and increasing sociopositive interactions with age, but can adapt to single housing if separated.Applied Animal Behaviour Science 214: 79-88.
    • Kästner N, Richter SH, Urbanik S, Kunert J, Waider J, Lesch K-P, Kaiser S, Sachser N. . ‘Brain serotonin deficiency affects female aggression.’ Scientific Reports 9, No. 1366.
    • Krakenberg V, Woigk I, Garcia Rodriguez L, Kästner N, Kaiser S, Sachser N, Richter SH. . ‘Technology or ecology? New tools to assess cognitive judgement bias in mice.’ Behavioural Brain Research 362: 279-287.
    • Richter SH, Hintze S. . ‘From the individual to the population – and back again? Emphasising the role of the individual in animal welfare science.’ Applied Animal Behaviour Science 212: 1-8.

    • Bodden C, Siestrup S, Palme R, Kaiser S, Sachser N, Richter SH. . ‘Evidence-based severity assessment: Impact of repeated versus single open-field testing on welfare in C57BL/6J mice.’ Behavioural Brain Research 336: 261-268.
    • Kästner N, Richter SH, Bodden C, Palme R, Kaiser S, Sachser N. . ‘Varying social experiences in adulthood do not differentially affect anxiety-like behavior but stress hormone levels.’ Frontiers in Behavioral Neuroscience 12: 72.
    • Richter SH. . „“Never replicate a successful experiment” - Gedanken über Unschärfe im Tierversuch.“ In Unschärfe – der Umgang mit fehlender Eindeutigkeit, herausgegeben von Freitag S, Geierhos M, Asmani R, Haug JI, 93-110.
    • Kafkafi N, Agassi J, Chesler EJ, Crabbe JC, Crusio WE, Eilam D, Gerlai R, Golani I, Gomez-Marin A, Heller R, Iraqi F, Jaljuli I, Karp NA, Morgan H, Nicholson G, Pfaff DW, Richter SH, Stark PB, Stiedl O, Stodden V, Tarantino LM, Tucci V, Valdar W, Williams RW, Würbel H, Benjamini Y. . ‘Reproducibility and replicability of rodent phenotyping in preclinical studies.’ Neuroscience & Biobehavioral Reviews 87: 218-232.
    • Richter SH. . „Aus dem VBIO.“ Biologie in unserer Zeit (BIUZ) 48: 23.
    • Sachser N, Richter SH, Kaiser S. . „Artgerecht/tiergerecht.“ In Handbuch Tierethik, herausgegeben von Ach JS, Borchers D, 155-160. Stuttgart: J. B. Metzler Verlag.
    • Richter SH, Sachser N, Kaiser S. . „Emotionen.“ In Handbuch Tierethik, herausgegeben von Ach JS, Borchers D, 64-69. Stuttgart: J. B. Metzler Verlag.

    • Meyer N, Jenikejew J, Richter SH, Kaiser S, Sachser N. . ‘Social experiences during adolescence affect anxiety-like behavior but not aggressiveness in male mice.’ Behavioural Brain Research 326: 147-153. doi: 10.1016/j.bbr.2017.03.017.
    • Richter SH. . ‘Systematic heterogenization for better reproducibility in animal experimentation.’ Lab Animal 46: 343-349. doi: 10.1038/laban.1330.
    • Kästner, N, Richter, SH, Gamer, M, Kaiser, S, Sachser, N. . ‘What a difference a day makes - female behaviour is less predictable near ovulation.’ Royal Society Open Science 4. doi: 10.1098/rsos.160998.

    • Remmes J, Bodden C, Richter SH, Lesting J, Sachser N, Pape H-C, Seidenbecher T. . ‘Impact of life history on fear memory and extinction.’ Frontiers in Behavioural Neuroscience 10: 185. doi: 10.3389/fnbeh.2016.00185.
    • Graulich DM, Kaiser S, Sachser N, Richter SH. . ‘Looking on the bright side of bias – validation of an affective bias test for laboratory mice.’ Applied Animal Behaviour Science 181: 173-181.
    • Richter SH, Spinello C, Macrì S. . ‘Improving external validity of experimental animal data.’ In Animal Models for Human Cancer: Discovery and Development of Novel Therapeutics, edited by Martic-Kehl MI, Schubiger PA, 41-60. Weinheim: Wiley-VCH.
    • Mallien AS, Palme R, Richetto J, Muzzillo C, Richter SH, Vogt MA, Inta D, Riva MA, Vollmayr B, Gass P. . ‘Daily exposure to a touchscreen-paradigm and associated food restriction evokes an increase in adrenocortical and neural activity in mice.’ Hormones and Behavior 81: 97-105.
    • Meyer N, Richter SH, Schreiber RS, Kloke V, Kaiser S, Lesch KP, Sachser N. . ‘The Unexpected Effects of Beneficial and Adverse Social Experiences during Adolescence on Anxiety and Aggression and Their Modulation by Genotype.’ Frontiers in Behavioral Neuroscience 10, No. 97. doi: 10.3389/fnbeh.2016.00097.
    • Richter SH, Kästner, N, Loddenkemper, DH, Kaiser, S, Sachser, N. . ‘A time to wean? Impact of weaning age on anxiety-like behaviour and stability of behavioural traits in full adulthood.’ PLoS ONE 11(12): e0167652. doi: 10.1371/journal.pone.0167652.
    • Richter, SH, Kästner, N, Kriwet, M, Kaiser, S, Sachser, N. . ‘Play matters - the surprising relationship between juvenile playfulness and anxiety in later life.’ Animal Behaviour 114: 261-271. doi: 10.1016/j.anbehav.2016.02.003.

    • Sachser N, Richter SH. . ‘Animals can tell us more.’ Behavioral and Brain Sciences 38: 44-45.
    • Macri S, Richter SH. . ‘The Snark was a Boojum – reloaded.’ Frontiers in Zoology 12: S20.
    • Bodden C, Richter SH, Schreiber RS, Kloke V, Gerss J, Palme R, Lesch K-P, Lewejohann L, Kaiser S, Sachser N. . ‘Benefits of adversity?! How life history affects the behavioral profile of mice varying in serotonin transporter genotype.Frontiers in Behavioral Neuroscience 9: 47.
    • Kästner N., Richter S.H., Lesch K.P., Schreiber R.S., Kaiser S., Sachser N. . ‘Benefits of a "vulnerability gene"? A study in serotonin transporter knockout mice.’ Behavioural Brain Research 283. doi: 10.1016/j.bbr.2015.01.031.

    • Richter SH, Sartorius A, Gass P, Vollmayr B. . ‘A matter of timing: harm reduction in learned helplessness.’ Behavioral and Brain Functions 10: 41.
    • Lima-Ojeda JM, Vogt MA, Richter SH, Dormann C, Schneider M, Gass P, Inta D. . ‘Lack of protracted behavioral abnormalities following intermittent or continuous chronic mild hypoxia in perinatal C57BL/6 mice.Neuroscience Letters 577C: 77-82. doi: 10.1016/j.neulet.2014.06.022.
    • Richter SH, Vogel AS, Ueltzhöffer K, Muzzillo C, Vogt MA, Lankisch K, Armbruster-Genç DJ, Riva MA, Fiebach CJ, Gass P, Vollmayr B. . ‘Touchscreen-paradigm for mice reveals cross-species evidence for an antagonistic relationship of cognitive flexibility and stability.Frontiers in Behavioral Neuroscience 8: 154. doi: 10.3389/fnbeh.2014.00154.
    • Richter SH, Wollmann E, Schmidt M, Zillmann U, Hellweg R, Sprengel R, Gass P. . ‘The effects of neonatal cryoanaesthesia-induced hypothermia on adult emotional behaviour and stress markers in C57BL/6 mice.Behavioural Brain Research 270C: 300-306. doi: 10.1016/j.bbr.2014.05.002.
    • Richter SH, Gass P, Fuss J. . ‘Resting Is Rusting: A Critical View on Rodent Wheel-Running Behavior.Neuroscientist 20(4): 313-325. doi: 10.1177/1073858413516798.

    • Hoyer C, Richter H, Brandwein C, Riva MA, Gass P. . ‘Preconceptional paternal exposure to a single traumatic event affects postnatal growth of female but not male offspring.NeuroReport 24, No. 15: 856. doi: 10.1097/WNR.0000000000000007.
    • Richter SH, Zeuch B, Lankisch K, Gass P, Durstewitz D, Vollmayr B. . ‘Where have I been? Where should I go? Spatial working memory on a radial arm maze in a rat model of depression.PLoS ONE 8, No. 4: e62458. doi: 10.1371/journal.pone.0062458.
    • Würbel H, Richter SH, Garner JP. . ‘Reply to: "Reanalysis of Richter et al. (2010) on reproducibility".Nature Methods 10, No. 5: 374. doi: 10.1038/nmeth.2446.
    • Richter SH, Zeuch B, Riva MA, Gass P, Vollmayr B. . ‘Environmental enrichment ameliorates depressive-like symptoms in young rats bred for learned helplessness.Behavioural Brain Research 252: 287. doi: 10.1016/j.bbr.2013.06.021.
    • Pignatelli M, Vollmayr B, Richter SH, Middei S, Matrisciano F, Molinaro G, Nasca C, Battaglia G, Ammassari-Teule M, Feligioni M, Nisticò R, Nicoletti F, Gass P. . ‘Enhanced mGlu5-receptor dependent long-term depression at the Schaffer collateral-CA1 synapse of congenitally learned helpless rats.Neuropharmacology 66: 339. doi: 10.1016/j.neuropharm.2012.05.046.
    • Fuss J, Richter SH, Steinle J, Deubert G, Hellweg R, Gass P. . ‘Are you real? Visual simulation of social housing by mirror image stimulation in single housed mice.Behavioural Brain Research 243: 191. doi: 10.1016/j.bbr.2013.01.015.

    • Hoyer C, Vogt MA, Richter SH, Zaun G, Zahedi Y, Maderwald S, Ladd ME, Winterhager E, Grümmer R, Gass P. . ‘Repetitive exposure to a 7 Tesla static magnetic field of mice in utero does not cause alterations in basal emotional and cognitive behavior in adulthood.Reproductive Toxicology 34, No. 1: 86-92. doi: 10.1016/j.reprotox.2012.03.006.
    • Richter SH, Schick A, Hoyer C, Lankisch K, Gass P, Vollmayr B. . ‘A glass full of optimism: enrichment effects on cognitive bias in a rat model of depression.Cognitive, Affective, and Behavioral Neuroscience 12, No. 3: 527. doi: 10.3758/s13415-012-0101-2.
    • Gross AN, Richter SH, Engel AK, Würbel H. . ‘Cage-induced stereotypies, perseveration and the effects of environmental enrichment in laboratory mice.Behavioural Brain Research 234, No. 1: 61. doi: 10.1016/j.bbr.2012.06.007.

    • Richter SH. . „Illusion der perfekten Kontrolle.“ Bild der Wissenschaft plus 2011: 20-23.
    • Richter SH. . „Illusion der perfekten Kontrolle.“ Vet Journal 12/11: 46-49.
    • Engel AK, Gross AN, Richter SH, Würbel H. . ‘Variation in stress reactivity affects cage-induced stereotypies in female CD-1 (ICR) mice.’ Applied Animal Behaviour Science 133: 101-108.
    • Chourbaji S, Hoyer C, Richter SH, Brandwein C, Pfeiffer N, Vogt MA, Vollmayr B, Gass P. . ‘Differences in mouse maternal care behavior - is there a genetic impact of the glucocorticoid receptor?PLoS ONE 6, No. 4: e19218. doi: 10.1371/journal.pone.0019218.
    • Gross AN, Engel AK, Richter SH, Garner JP, Würbel H. . ‘Cage-induced stereotypies in female ICR CD-1 mice do not correlate with recurrent perseveration.Behavioural Brain Research 216, No. 2: 613. doi: 10.1016/j.bbr.2010.09.003.
    • Richter SH, Garner JP, Zipser B, Lewejohann L, Sachser N, Touma C, Schindler B, Chourbaji S, Brandwein C, Gass P, van Stipdonk N, van der Harst J, Spruijt B, Võikar V, Wolfer DP, Würbel H. . ‘Effect of population heterogenization on the reproducibility of mouse behavior: a multi-laboratory study.PLoS ONE 6, No. 1: e16461. doi: 10.1371/journal.pone.0016461.

    • Richter SH. . Standardization in animal experiments: Necessity or fallacy? Dissertation thesis, Universität Münster. Münster.
    • Richter SH, Garner JP, Auer C, Kunert J, Würbel H. . ‘Systematic variation improves reproducibility of animal experiments.Nature Methods 7, No. 3: 167. doi: 10.1038/nmeth0310-167.

    • Ambrée O, Richter H, Sachser N, Lewejohann L, Dere E, de Souza Silva MA, Herring A, Keyvani K, Paulus W, Schäbitz WR. . ‘Levodopa Ameliorates Learning and Memory Deficits in a Murine Model of Alzheimer's Disease.Neurobiology of Aging 30, No. 8: 1192-1204. doi: 10.1016/j.neurobiolaging.2007.11.010.
    • Richter SH, Garner JP, Würbel H. . ‘Environmental standardization: cure or cause of poor reproducibility in animal experiments?Nature Methods 6, No. 4: 257. doi: 10.1038/nmeth.1312.

    • Richter H, Ambrée O, Lewejohann L, Herring A, Keyvani K, Paulus W, Palme R, Touma C, Schäbitz WR, Sachser N. . ‘Wheel-Running in a Transgenic Mouse Model of Alzheimer's Disease: Protection or Symptom?Behavioural Brain Research 190, No. 1: 74-84. doi: 10.1016/j.bbr.2008.02.005.

    • Richter SH. . Was ist Glück?.