Research Overview of the Hennecke Group at the WWU Münster
© AK Hennecke
  • Organohalogen Chemistry

    The Hennecke group is interested in research in the areas of organic and bioorganic chemistry. A key component of research focuses on organohalogen compounds, especially of the heavier halogens chlorine, bromine and iodine. Since such compounds occur as natural products and are valuable intermediates in organic synthesis, the group is developing catalytic asymmetric methods for the regio- and stereoselective synthesis of these compounds.

    Selected Publications:

    AK Hennecke Research 05
    Homohalocyclization: Electrophilic Bromine-Induced Cyclizations of Cyclopropanes, C. Rösner, U. Hennecke, Org. Lett. 2015, 17, 3226-3229.
    © AK Hennecke
    AK Hennecke Research 01
    Enantioselective, Desymmetrizing Bromolactonization of Alkynes, M. Wilking, C. Mück-Lichtenfeld, C. G. Daniliuc, U. Hennecke, J. Am. Chem. Soc. 2013, 135, 8133-8136.
    © AK Hennecke
    AK Hennecke Research 02
    Enantioselective Haloetherification by Asymmetric Opening of meso-Halonium Ions, U. Hennecke, C. H. Müller, R. Fröhlich, Org. Lett. 2011, 13, 860-863.
    © AK Hennecke
    AK Hennecke Research 03
    For a current review: New Catalytic Approaches towards the Enantioselective Halogenation of Alkenes, U. Hennecke, Chem. Asian J. 2012, 7, 456-465.
    © AK Hennecke
  • DNA as a construction material in catalysis and material science

    We are also interested in bioorganic chemistry, especially the modification of nucleic acids and the application of DNA in nanotechnology and catalysis. This includes the development of methods for DNA modification using photochemistry or transition metal-catalyzed methodology. In the framework of the SFB 858 DNA is modified with transition metal complexes to create novel hybrid catalysts which are applied in asymmetric catalysis.

    Current Publication:

    AK Hennecke Research 04a
    The influence of G-quadruplex structure on DNA-based asymmetric catalysis using the G-quadruplex-bound cationic porphyrin TMPyP4•Cu, M. Wilking, U. Hennecke, Org. Biomol. Chem. 2013, 11, 6940-6945.
    © AK Hennecke