Enantioselective Catalysis by Using Short, Structurally Defined DNA Hairpins as Scaffold for Hybrid Catalysts
© AK Hennecke
An Enantioselective Iodolactonization/Cross-Coupling Protocol for the Synthesis of Highly-Substituted Enol Lactones,
C. Fricke, M. Wilking, C. G. Daniliuc, U. Hennecke,
Eur. J. Org. Chem. 2018, accepted. [doi:10.1002/ejoc.201800642]
PqsL uses reduced flavin to produce 2-hydroxylaminobenzoylacetate, a preferred PqsBC substrate in alkyl quinolone biosynthesis in Pseudomonas aeruginosa,
S. L. Drees, S. Ernst, B. Belviso, N. Jagmann, U. Hennecke, S. Fetzner,
J. Biol. Chem. 2018, accepted. [doi:10.1074/jbc.RA117.000789]
Chemical Modification and Detoxification of the Pseudomonas aeruginosa Toxin 2-Heptyl-4-hydroxyquinoline N-Oxide by Environmental and Pathogenic Bacteria,
S. Thierbach, F. S. Birmes, M. C. Letzel, U. Hennecke, S. Fetzner,
ACS Chem. Biol. 2017, 12, 2305-2312. [doi:10.1021/acschembio.7b00345]
Stable Bromiranium Ions with Weakly-Coordinating Counterions as Efficient Electrophilic Brominating Agents,
C. Ascheberg, J. Bock, F. Buß, C. Mück-Lichtenfeld, C. G. Daniliuc, K. Bergander, F. Dielmann, U. Hennecke,
Chem. Eur. J. 2017, 23, 11578-11586. [doi:10.1002/chem.201701643]
Why DNA is a More Effective Scaffold than RNA in Nucleic Acid-based Asymmetric Catalysis – Supramolecular Control of Cooperative Effects,
J. J. Marek, U. Hennecke,
Chem. Eur. J. 2017, 23, 6009-6013. [doi:10.1002/chem.201606043]
Enantioselective Catalysis using short, structurally-defined DNA Hairpins as Scaffold for Hybrid Catalysts,
J. J. Marek, R. Singh, A. Heuer, U. Hennecke,
Chem. Eur. J. 2017, 23, 6004-6008. [doi:10.1002/chem.201606002]
Synthesis of Chiral Heterocyclic N-Haloamides and -imides and their Application as Halogenating Agents and Mechanistic Probes,
U. Hennecke, C. H. Müller, C. G. Daniliuc,
Eur. J. Org. Chem. 2017, 484-490. [doi:10.1002/ejoc.201601159]
Monomeric cinchona alkaloid-based catalysts for highly enantioselective bromolactonisation of alkynes,
M. Wilking, C. G. Daniliuc, U. Hennecke,
Chem. Eur. J. 2016, 22, 18601-18607. [doi:10.1002/chem.201604003]
PqsBC, a condensing enzyme in the biosynthesis of the Pseudomonas aeruginosa quinolone signal: crystal structure, inhibition, and reaction mechanism,
S. L. Drees, C. Li, F. Prasetya, M. Saleem, I. Dreveny, P. Williams, U. Hennecke, J. Emsley, S. Fetzner,
J. Biol. Chem. 2016, 291, 6610-6624. [doi:10.1074/jbc.M115.708453]
1-Iodo-n-Heteroatom-Functionalized Alkanes (n ≥ 2) with Both Functions Formed Simultaneously: Synthesis by Addition across C=C Bond,
U. Hennecke,
Science of Synthesis Vol 35 (Update 2015/2) 2015, 449-465. [doi:]
Iodoalkanes: Synthesis by Addition to π-Type C-C-Bonds,
U. Hennecke,
Science of Synthesis Vol 35 (Update 2015/2) 2015, 437-448. [doi:]
Homohalocyclization: Electrophilic Bromine-Induced Cyclizations of Cyclopropanes,
C. Rösner, U. Hennecke,
Org. Lett. 2015, 17, 3226-3229. [doi:10.1021/acs.orglett.5b01315]]
Asymmetric, Organocatalytic Bromolactonization of Allenoic Acids,
M. Wilking, C. G. Daniliuc, U. Hennecke,
Synlett 2014, 25, 1701-1704. [doi:10.1055/s-0034-1378278]
Enantioselective haloetherifications catalyzed by BINOL phosphates - From symmetrical alkenediols to simple alkenols,
C. H. Müller, C. Rösner, U. Hennecke,
Chem. Asian J. 2014, 9, 2162-2169. [doi:10.1002/asia.201402229]
Desymmetrization as a Strategy in Asymmetric Halocyclization Reactions,
M. Wilking, U. Hennecke,
Synlett 2014, 25, 1633-1637. [doi:10.1055/s-0033-1341160]
Addition Reactions with Formation of Carbon–Halogen Bonds,
U. Hennecke, T. Wald, C. Rösner, T. Robert, M. Oestreich,
in Comprehensive Organic Synthesis (2nd Edition); G. A. Molander, P. Knochel (Eds.), Elsevier, Oxford, Vol. 7 (Oxidation) 2014, 638-691. [doi:10.1016/B978-0-08-097742-3.00725-4]
The influence of G-quadruplex structure on DNA-based asymmetric catalysis using the G-quadruplex-bound cationic porphyrin TMPyP4·Cu,
M. Wilking, U. Hennecke,
Org. Biomol. Chem. 2013, 11, 6940-6945. [doi:10.1039/C3OB41366G]
Enantioselective, Desymmetrizing Bromolactonization of Alkynes,
M. Wilking, C. Mück-Lichtenfeld, C. G. Daniliuc, U. Hennecke,
J. Am. Chem. Soc. 2013, 135, 8133-8136. [doi:10.1021/ja402910d]
Revealing the Positive Side of Fluorine (Perspective),
U. Hennecke,
Science 2013, 340, 41-42. [doi: 10.1126/science.1236150]
Efficient Synthesis of Chiral 2,2’-Bipyrrolidines by an anti-Selective Alkene Diamination,
C. H. Müller, R. Fröhlich, C. G. Daniliuc, U. Hennecke,
Org. Lett. 2012, 14, 5944-5947. [doi:10.1021/ol302855z]
Hydrolase-Like Properties of a Cofactor-Independent Dioxygenase,
S. Thierbach, K. Büldt-Karentzopoulos, A. Dreiling, U. Hennecke, S. König, S. Fetzner,
ChemBioChem 2012, 13, 1125-1127. [doi:10.1002/cbic.201200152];
A New approach towards the Asymmetric Fluorination of Alkenes Using Anionic Phase-Transfer Catalysts (Highlight),
U. Hennecke,
Angew. Chem. Int. Ed. 2012, 51, 4532-4535. [doi:10.1002/anie.201200831]
New Catalytic Approaches towards the Enantioselective Halogenation of Alkenes,
U. Hennecke,
Chem. Asian J. 2012, 7, 456-465. [doi:10.1002/asia.201100856];
Catalytic, Asymmetric, Bromine-Induced Semipinacol Rearrangements at Unactivated Double Bonds,
C. H. Müller, M. Wilking, A. Rühlmann, B. Wibbeling, U. Hennecke,
Synlett 2011, 2043-2047. [doi:10.1055/s-0030-1260983]
Enantioselective Haloetherification by Asymmetric Opening of meso-Halonium Ions,
U. Hennecke, C. H. Müller, R. Fröhlich,
Org. Lett. 2011, 13, 860-863. [doi:10.1021/ol1028805]

Sequential Double α-Arylation of N-Allylureas by Asymmetric Deprotonation and N→C Aryl Migration,
D. J. Tetlow, U. Hennecke, J. Raftery, M. J. Waring, D. S. Clarke, J. Clayden,
Org. Lett. 2010, 12, 5442-5445. [doi:10.1021/ol102155h]
The origin of the conformational preference of N,N'-diaryl-N,N'-dimethyl ureas,
J. Clayden, U. Hennecke, M. A. Vincent, I. H. Hillier, M. Helliwell,
Phys. Chem. Chem. Phys 2010, 12, 15056-15064. [doi:10.1039/C0CP00571A ]
Crystal Structure of the T(6-4)C Lesion in Complex with a (6-4) DNA Photolyase and Repair of UV-Induced (6-4) and Dewar Photolesions,
A. F. Glas, S. Schneider, M. J. Maul, U. Hennecke, T. Carell,
Chem. Eur. J. 2009, 15, 10387-10396. [doi:10.1002/chem.200901004]
N to C aryl migration in lithiated carbamates: alpha-arylation of benzylic alcohols,
J. Clayden, W. Farnaby, D. M. Grainger, U. Hennecke, M. Mancinelli, D. J. Tetlow, I. H. Hillier, M. A. Vincent,
J. Am. Chem. Soc. 2009, 131, 3410-3411. [doi:10.1021/ja808959e]
α-Arylation of cyclic amines by aryl transfer in lithiated ureas,
R. Bach, J. Clayden, U. Hennecke,
Synlett 2009, 421-424. [doi:10.1055/s-0028-1087543]
Recognition and repair of UV lesions in loop structures of duplex DNA by DASH-type cryptochrome,
R. Pokorny, T. Klar, U. Hennecke, T. Carell, A. Batschauer, L.-O. Essen,
Proc. Natl. Acad. Sci. U. S. A. 2008, 105, 21023-21027. [doi:10.1073 pnas.0805830106];
α-Pyridylation of Chiral Amines via Urea Coupling, Lithiation and Rearrangement,
J. Clayden, U. Hennecke,
Org. Lett. 2008, 3567-3570. [doi:10.1021/ol801332n]
A general route to 4-C-substituted pyrimidine nucleosides,
U. Hennecke, D. Kuch, T. Carell,
Synthesis 2007, 929-935. [doi:10.1055/s-2007-965935]
CPD damage recognition by transcribing RNA polymerase II,
F. Brückner, U. Hennecke, T. Carell, P. Cramer,
Science 2007, 315, 859-862. [doi:10.1126/science.1135400 ]
Natural and non-natural antenna chromophores in the DNA Photolyase from Thermus Thermophilus,
T. Klar, G. Kaiser, U. Hennecke, T. Carell, A. Batschauer, L.-O. Essen,
ChemBioChem 2006, 7, 1798-1806. [doi:10.1002/cbic.200600206];
Characterization of a New Thermophilic Spore Photoproduct Lyase from Geobacillus stearothermophilus (SplG) with Defined Lesion Containing DNA Substrates,
J. C. Pieck, U. Hennecke, A. J. Pierik, M. G. Friedel, T. Carell,
J. Biol. Chem. 2006, 281, 36317-36326. [doi:10.1074/jbc.M607053200 ]
Investigation of the Pathways of Excess Electron Transfer in DNA with Flavin-Donor and Oxetane-Acceptor Modified DNA Hairpins,
S. Breeger, M. von Meltzer, U. Hennecke, T. Carell,
Chem. Eur. J. 2006, 12, 6469-6477. [doi:10.1002/chem.200600074]
Crystal structure of a photolyase bound to a CPD-like DNA lesion after in situ repair,
A. Mees, T. Klar, P. Gnau, U. Hennecke, A. P. M. Eker, T. Carell, L.-O. Essen,
Science 2004, 306, 1789-1793. [doi:10.1126/science.1101598 ]
Excess electron transfer in defined donor-nucleobase and donor-DNA-acceptor systems,
C. Behrens, M. K. Cichon, F. Grolle, U. Hennecke, T. Carell,
Top. Curr. Chem. 2004, 236, 187-204. [doi:10.1007/b94416]
Excess electron transport through DNA: a single electron repairs more than one UV-induced lesion,
B. Giese, B. Carl, T. Carl, T. Carell, C. Behrens, U. Hennecke, O. Schiemann, E. Feresin,
Angew. Chem. Int. Ed. 2004, 43, 1848-1851. [doi:10.1002/anie.200353264]
Excess electron-transfer-based repair of a cis-syn Thymine Dimer in DNA is not sequence dependent,
S. Breeger, U. Hennecke, T. Carell,
J. Am. Chem. Soc. 2004, 126, 1302-1303. [doi:10.1021/ja038358t]
Design of luminescent polymers for LEDs,
A. B. Holmes, A. D. Bond, J. E. Davies, C. Fischmeister, J. Frey, U. Hennecke, J. Li, Y. Ma, R. E. Martin, I. D. Rees, K. Robinson, T. Sano, F. Cacialli, S. F. Lim, R. H. Friend,
Mater. Res. Soc. Symp. Proc. 2002, 708, 185-195. [doi:10.1557/PROC-708-BB5.2]
New family of polyfluorene copolymers for light emitting devices,
A. B. Holmes, I. Rees, T. Sano, C. Fischmeister, J. Frey, U. Hennecke, C.-S. Tuan, B. S. Chuah, Y. Ma, R. E. Martin, J. Li, N. Feeder, A. Bond, F. Cacialli, S. Lim, R. Friend,
Proceedings of SPIE-The International Society for Optical Engineering 2003, 4464, 42-48. [doi:10.1117/12.457502]