Participation in the Cluster of Excellence

CiM Principal Investigator
Executive Board Member
Educational Steering Committee Member
Spokesperson of the CiM-IMPRS Graduate School

  • Research Area A.1: Cellular Polarization and Changes in Cell Shape
  • Research Area A.3: Functional Membrane Domains in Neuronal and Non-Neuronal Compartmentalization
  • Project FF-2017-13 – Exploring the role of vesicle transport and cell morphology during neuronal polarization: imaging and modeling approaches (Jan-Frederik Pietschmann, Andreas Püschel; project time: 11/2017 - 12/2018)
  • Project FF-2014-06 – Analysis of cell-cell interactions during neuronal migration in the developing cortex by live cell imaging and cell shape quantification (Martin Burger, Andreas Püschel, project time: 07/2014 - 06/2016)

CiM Papers


Dogliotti G, Kullmann L, Dhumale P, Thiele C, Panichkina O, Mendl G, Houben R, Haferkamp S, Puschel AW, Krahn MP. Membrane-binding and activation of LKB1 by phosphatidic acid is essential for development and tumour suppression. Nat Commun 2017;8: 15747. Abstract
Shah B, Lutter D, Tsytsyura Y, Glyvuk N, Sakakibara A, Klingauf J, Puschel AW. Rap1 GTPases Are Master Regulators of Neural Cell Polarity in the Developing Neocortex. Cereb Cortex 2017;27: 1253-1269. Abstract


Shah B, Lutter D, Bochenek ML, Kato K, Tsytsyura Y, Glyvuk N, Sakakibara A, Klingauf J, Adams RH, Puschel AW. C3G/Rapgef1 Is Required in Multipolar Neurons for the Transition to a Bipolar Morphology during Cortical Development. PLoS One 2016;11: e0154174. Abstract


Shah B, Puschel AW. In vivo functions of small GTPases in neocortical development. Biol Chem 2014;395: 465-476. Abstract
Yang R, Kong E, Jin J, Hergovich A, Puschel AW. Rassf5 and Ndr kinases regulate neuronal polarity through Par3 phosphorylation in a novel pathway. J Cell Sci 2014;127: 3463-3476. Abstract