Participation in the Cluster of Excellence

CiM Principal Investigator
Coordinator Research Area B
Scientific Steering Committee Member
CiM-IMPRS Graduate School Member

  • Research Area A.1: Cellular Polarization and Changes in Cell Shape
  • Research Area A.6: Motion Analysis in Cellular Systems
  • Research Area B.1: Formation and Properties of Epithelial and Endothelial Barriers
  • Projekt FF-2016-06: FIM4D: Automated FIM-based in-vial activity monitoring and tracking for locomotion analysis of Drosophila larvae (Xiaoyi Jiang, Christian Klämbt, project time: 07/2016 - 10/2018)
  • Project FF-2014-12: Metabolic crosstalk across the blood brain barrier (Christian Klämbt, Matthias Letzel, Stefanie Limmer, 07/2014 - 06/2016)
© CiM - Peter Grewer

”My job isn’t ‘work’ – it’s my life!“

Prof. Christian Klämbt is a scientist heart and soul. He studies glial cells, one of the main components of the brain. His overriding aim is to understand how the brain and all its wonders work. But he also knows that this is an aim that cannot be reached easily. Read the interview


  • Jiang X, Klämbt C, Risse B, Valkov D. Verfahren und Vorrichtung zur Erfassung wenigsten eines Tieres. DE 102012016122; 20/02/2014.

CiM Papers

all papers by Christian Klämbt (PubMed)


Berh D, Scherzinger A, Otto N, Jiang X, Klambt C, Risse B. Automatic non-invasive heartbeat quantification of Drosophila pupae. Comput Biol Med 2018;93: 189-199. Abstract
Schuermann S, Steffes G, Manikowski D, Kastl P, Malkus U, Bandari S, Ohlig S, Ortmann C, Rebollido-Rios R, Otto M, Nusse H, Hoffmann D, Klambt C, Galic M, Klingauf J, Grobe K. Proteolytic processing of palmitoylated Hedgehog peptides specifies the 3-4 intervein region of the Drosophila wing. Elife 2018;7: epub. Abstract


Berh D, Risse B, Michels T, Otto N, Jiang X, Klambt C. An FIM-Based Long-Term In-Vial Monitoring System for Drosophila Larvae. IEEE Trans. Biomed. Eng. 2017;64: 1862-1874. Abstract
Risse B, Berh D, Otto N, Klambt C, Jiang X. FIMTrack: An open source tracking and locomotion analysis software for small animals. PLoS Comput Biol 2017;13: e1005530. Abstract
Risse B, Otto N, Berh D, Jiang X, Kiel M, Klambt C. FIM2c : A Multi-Colour, Multi-Purpose Imaging System to Manipulate and Analyse Animal Behaviour. IEEE Trans Biomed Eng 2017;64: 610-620. Abstract


Otto N, Risse B, Berh D, Bittern J, Jiang X, Klambt C. Interactions among Drosophila larvae before and during collision. Sci Rep 2016;6: 31564. Abstract
Sasse S, Klambt C. Repulsive Epithelial Cues Direct Glial Migration along the Nerve. Dev Cell 2016;39: 696-707. Abstract


Goudarzi M, Mildner K, Babatz F, Riedel D, Klambt C, Zeuschner D, Raz E. Correlative Light and Electron Microscopy of Rare Cell Populations in Zebrafish Embryos Using Laser Marks. Zebrafish 2015;12: 470-473. Abstract
Risse B, Berh D, Otto N, Jiang X, Klambt C. Quantifying subtle locomotion phenotypes of Drosophila larvae using internal structures based on FIM images. Comput Biol Med 2015;63: 269-276. Abstract
Schirmeier S, Klambt C. The Drosophila blood-brain barrier as interface between neurons and hemolymph. Mech Dev 2015;138 Pt 1: 50-55. Abstract


Kim SN, Jeibmann A, Halama K, Witte HT, Walte M, Matzat T, Schillers H, Faber C, Senner V, Paulus W, Klambt C. ECM stiffness regulates glial migration in Drosophila and mammalian glioma models. Development 2014;141: 3233-3242. Abstract
Lammel U, Bechtold M, Risse B, Berh D, Fleige A, Bunse I, Jiang X, Klambt C, Bogdan S. The Drosophila FHOD1-like formin Knittrig acts through Rok to promote stress fiber formation and directed macrophage migration during the cellular immune response. Development 2014;141: 1366-1380. Abstract
Risse B, Otto N, Berh D, Jiang X, Klambt C. FIM imaging and FIMtrack: two new tools allowing high-throughput and cost effective locomotion analysis. J Vis Exp 2014: e52207. Abstract


Risse B, Thomas S, Otto N, Lopmeier T, Valkov D, Jiang X, Klambt C. FIM, a novel FTIR-based imaging method for high throughput locomotion analysis. PLoS One 2013;8: e53963. Abstract