• Participation in “Cells in Motion”

    • Research interests: cell-cell interactions, cell polarity, cell adhesion molecules, Junctional Adhesion Molecules (JAMs), integrins

           FF-2016-01 – Rotational motion in epithelial morphogenesis: Analysis of conserved molecular
                Principal investigators: Sven Bogdan, Klaus Ebnet
                Project time: 07/2016 - 06/2018

  • Papers in the research focus “cell dynamics and imaging”

    all papers by Klaus Ebnet (PubMed)


    Otani T, Nguyen TP, Tokuda S, Sugihara K, Sugawara T, Furuse K, Miura T, Ebnet K, Furuse M. Claudins and JAM-A coordinately regulate tight junction formation and epithelial polarity. J Cell Biol 2019;218: 3372-3396. Abstract


    Ebnet K, Kummer D, Steinbacher T, Singh A, Nakayama M, Matis M. Regulation of cell polarity by cell adhesion receptors. Semin Cell Dev Biol 2018;81: 2-12. Abstract
    Kummer D, Ebnet K. Junctional Adhesion Molecules (JAMs): The JAM-Integrin Connection. Cells 2018;7: E25. Abstract
    Steinbacher T, Ebnet K. The regulation of junctional actin dynamics by cell adhesion receptors. Histochem Cell Biol 2018;150: 341-350. Abstract
    Steinbacher T, Kummer D, Ebnet K. Junctional adhesion molecule-A: functional diversity through molecular promiscuity. Cell Mol Life Sci 2018;75: 1393-1409. Abstract


    Ebnet K. Junctional Adhesion Molecules (JAMs): Cell Adhesion Receptors With Pleiotropic Functions in Cell Physiology and Development. Physiol Rev 2017;97: 1529-1554. Abstract
    Ebnet K, Kummer D, Steinbacher T, Singh A, Nakayama M, Matis M. Regulation of cell polarity by cell adhesion receptors. Semin Cell Dev Biol 2017Abstract


    Brinkmann BF, Steinbacher T, Hartmann C, Kummer D, Pajonczyk D, Mirzapourshafiyi F, Nakayama M, Weide T, Gerke V, Ebnet K. VE-cadherin interacts with cell polarity protein Pals1 to regulate vascular lumen formation. Mol Biol Cell 2016;27: 2811-2821. Abstract
    Squarr AJ, Brinkmann K, Chen B, Steinbacher T, Ebnet K, Rosen MK, Bogdan S. Fat2 acts through the WAVE regulatory complex to drive collective cell migration during tissue rotation. J Cell Biol 2016;212: 591-603. Abstract


    Tuncay H, Brinkmann BF, Steinbacher T, Schurmann A, Gerke V, Iden S, Ebnet K. JAM-A regulates cortical dynein localization through Cdc42 to control planar spindle orientation during mitosis. Nat Commun 2015;6: 8128. Abstract


    Peddibhotla SSD, Brinkmann BF, Kummer D, Tuncay H, Nakayama M, Adams RH, Gerke V, Ebnet K. Tetraspanin CD9 links junctional adhesion molecule-A to alphavbeta3 integrin to mediate basic fibroblast growth factor-specific angiogenic signaling. Mol Biol Cell 2013;24: 933-944. Abstract


    Iden S, Misselwitz S, Peddibhotla SSD, Tuncay H, Rehder D, Gerke V, Robenek H, Suzuki A, Ebnet K. aPKC phosphorylates JAM-A at Ser285 to promote cell contact maturation and tight junction formation. J Cell Biol 2012;196: 623-639. Abstract