• Beteiligung an „Cells in Motion“

    • Forschungsinteressen: matrix-dependent morphogen release and transport, in vivo visualization of dynamic matrix biosynthesis, “pre-patterning” and turnover, development of matrix-modification-specific and morphogen-specific nanobodies for in vivo visualization of matrix modifications and morphogen gradients, plasma membrane cholesterol-dependent cellular patterning, morphogen-regulated cellular compartmentalization
    • Projekt FF-2015-02 – In vitro und in vivo Untersuchungen zur Membranabhängigkeit der Hh Sekretion (Milos Galic, Kay Grobe, Projektlaufzeit: 07/2015 - 06/2016)

  • Publikationen im Forschungsschwerpunkt „Zelldynamik und Bildgebung“

    Publikationen von Kay Grobe

    2018

    Schuermann S, Steffes G, Manikowski D, Kastl P, Malkus U, Bandari S, Ohlig S, Ortmann C, Rebollido-Rios R, Otto M, Nusse H, Hoffmann D, Klambt C, Galic M, Klingauf J, Grobe K. Proteolytic processing of palmitoylated Hedgehog peptides specifies the 3-4 intervein region of the Drosophila wing. Elife 2018;7: e33033. Abstract

    2016

    Jakobs P, Schulz P, Ortmann C, Schurmann S, Exner S, Rebollido-Rios R, Dreier R, Seidler DG, Grobe K. Bridging the gap: heparan sulfate and Scube2 assemble Sonic hedgehog release complexes at the surface of producing cells. Sci Rep 2016;6: 26435. Abstract

    2015

    Ortmann C, Pickhinke U, Exner S, Ohlig S, Lawrence R, Jboor H, Dreier R, Grobe K. Sonic hedgehog processing and release are regulated by glypican heparan sulfate proteoglycans. J Cell Sci 2015;128: 2374-2385. Abstract

    2014

    Xu Y, Pektor S, Balkow S, Hemkemeyer SA, Liu Z, Grobe K, Hanley PJ, Shen L, Bros M, Schmidt T, Bahler M, Grabbe S. Dendritic cell motility and T cell activation requires regulation of Rho-cofilin signaling by the Rho-GTPase activating protein myosin IXb. J Immunol 2014;192: 3559-3568. Abstract