PhD Student
Computational Drug Discovery

M.Sc. Pharmaceutical Chemistry and Technology

E-Mail: matteo.gozzi@uni-muenster.de
Institute of Pharmaceutical and Medicinal Chemistry
Corrensstr. 48
48149 Münster

 

 

 

 

 

Research Topic

As a PhD student within the Chembion research training network, I focus on studying the molecular mechanisms behind small molecule modulators of ion channels. Specifically, I employ computational approaches, including molecular dynamics and docking studies, to elucidate the details of ligand-protein interactions of compounds targeting KCa3.1, a calcium-activated potassium channel with significant therapeutic potential.

My research background also includes work on G protein-coupled receptors, particularly the Neuropeptide S receptor (NPSR) and the Nociceptin/Orphanin FQ receptor (NOP). Through in-silico investigations, I have explored the interaction mechanisms of both small molecule and peptide ligands, and contributed to the rational design of novel bioactive compounds for both targets.

Publications

Previous publications can be found on Google Scholar.