IRTG Münster-Toronto
Corrensstr. 30 D-48149 Münster
Tel: +49 251 83-33111
Fax: +49 251 83-33108



Mild C-F Activation in Perflourinated Arenes through Photosensitized Insertion of Isonitriles at 350 nm
Frauke Weidlich, Naoto Esumi, Dongyang Chen, Christian Mück-Lichtenfeld, Eli Zysman-Colman, Armido Studer
Adv. Synth. Catal., 2020, 362, 376   [doi:10.1002/adsc.201901126]
Formation of an NHC-stabilized heterocyclic housane and its isomerization into a cyclopentenyl anion analogue
Benedikt J. Guddorf,   Christian Mück-Lichtenfeld,  Alexander Hepp, Felicitas Lips
Chem. Commun., 2019, 55, 12896   [doi:10.1039/C9CC07109A]
Metal Hydride ibrations: The Trans Effect of the Hydride
D. Schnieders, B. T. H. Tsui, M.M.H. Sung, M. R. Bortolus, G. J. Schrobilgen, J. Nuegebauer, R. H. Morris
Inorg. Chem. 2019, 58, 12467 [doi:_10.1021/acs.inorgchem.9b0230]
Regioselective N- and C-Metalation of Neutral 2-Halogenobenzimidazole Derivatives
R. Das, J. Blumenberg, C. Daniliuc, D. Schnieders, J. Neugebauer, Y.-F. Han, F.E. Hahn
Organometallics 2019, 38, 3278 [doi:10.1021/acs.organomet.9b00357]
Synthesis of Iron(0) Complexes Bearing Protic NHC LIagands: Synthesis and Catalytic Activity
C. Mühlen, J. Linde, L. Rakers, T. T. Y. Tan, F. Kampert, F. Glorius, F. E. Hahn
Organometallics 2019, 38, 2417-2421 [doi: 10.1021/acs.organomet.9b00260]

The formation of all-cis-(multi)fluorinated piperidines by a dearomatization–hydrogenation process

Zackaria Nairoukh , Marco Wollenburg, Christoph Schlepphorst, Klaus Bergander, Frank Glorius Nature Chem. 2019, 11, 264-270 [doi: 10.1038/s41557-018-0197-2]


Palladium-Catalyzed Decarboxylative γ-Arylation for the Synthesis of Tetrasubstituted Chiral Allenes
Ina Scheipers, Christian Mück-Lichtenfeld, Armido Studer
Angew. Chem. Int. Ed. 201958, 6545-6548 [doi:10.1002/anie.201901848]


Hydrogenation of Borylated Arenes

Marco Wollenburg, Daniel Moock, Frank Glorius

Angew. Chem. Int. Ed. 2019, 58, 6549-6553 [doi: 10.1002/anie.201810714]


Enantioselective synthesis of 2-oxazolidinones by ruthenium(II)–NHC-catalysed asymmetric hydrogenation of 2-oxazolones

Wei Li, Marco Wollenburg, Frank Glorius

Chem. Sci. 2018, 9, 6260-6263 [doi: 10.1039/c8sc01869c]


Palladium-Catalyzed Hydride Addition/C–H Bond Activation Cascade: Cycloisomerization of 1,6-Diynes
Jose F. Rodriguez, Katherine I. Burton, Ivan Franzoni, David A. Petrone, Ina Scheipers, Mark Lautens
Org. Lett. 2018, 20, 6915-6919 [doi:10.1021/acs.orglett.8b03057]


Stereoselective Palladium-Catalyzed Decarboxylative γ-Arylation of Acyclic b,γ-Unsaturated Carboxylic Acids
Ina Scheipers, Eva Koch, Armido Studer
Org. Lett. 201719, 1741-1743 [doi:10.1021/acs.orglett.7b00512]

39. Imidazole-stabilized, electron-deficient boron
Kaoko Sato, Tristan Tsai Yuan Tan, Felix Schäfers, F. Ekkehardt Hahn, Douglas W. Stephan
Dalton Trans. 2017, 46, 16404–16407 [doi:10.1039/c7dt04030j]
38. Radical Difluoromethylation of Thiols with (Difluorome-thyl)triphenylphosphonium Bromide
N. B. Heine, A. Studer
Org. Lett. 2017, 19, 4150–4153 [doi:10.1021/acs.orglett.7b02109]
37. Heterocyclic Digallanates, Encapsulation of Lithium Cations in Organometallic Cages and C-H Bond Activation
W. Uhl, A. Hentschel, D. Kovert, J. Kösters, M. Layh
Eur. J. Inorg. Chem. 2015, 2486–2496 [doi:10.1002/ejic.201500207]
36. Halogenated Triphenyl Gallium and Indium in Frustrated Lewis Pair Activations and Hydrogenation Catalysis
M. Xu, J. Possart, A. E. Waked, J. Roy, W. Uhl, D. W. Stephan
Phil. Trans. R. Soc. A., [doi:10-1098/rsta.2017-0014]
35. DNA Films Containing the Artificial Nucleobase Imidazole Mediate Charge Transfer in a Silver(I)-Responsive Way
J. C. Léon, Z. She, A. Kamal, M. H. Shamsi, J. Müller, H.-B. Kraatz
Angew. Chem. Int. Ed. 2017, 56 [doi:10.1002/anie.201700248] Angew. Chem. 2017, 129 [doi:10.1002/ange.201700248]
34. Dual 5' cap labeling based on regioselective RNA methyltransferases and bioorthogonal reactions
J. M. Holstein, F. Muttach, S. H. H. Schiefelbein, A. Rentmeister
Chemistry 2017 [doi:10.1002/chem.201604816]
33. Single-Step Synthesis of Organometallic Molecular Squares from NR,NR′,NR′′,NR′′′-Substituted Benzobiscarbenes
N. Sinha, F. Roelfes, A. Hepp, F. E. Hahn
Chem. Eur. J. 2016 [doi:10.1002/chem.201604996]
32. Regioselective C8-metalation of N-phosphine tethered adenine derivatives via C8–H activation
D. Brackemeyer, C. Schulte to Brinke, F. Roelfes, F. E. Hahn
Dalton Trans. 2017 [doi:10.1039/C7DT00682A]
31. Synthesis and Reactivity of Intramolecularly NHC-Stabilized Germylenes and Stannylenes
D. Paul, F. Heins, S. Krupski, A. Hepp, C. G. Daniliuc, K. Klahr, J. Neugebauer, F. Glorius, F. E. Hahn
Organometallics 2017, 36, 1001–1008 [doi:10.1021/acs.organomet.6b00925]
30. Quantifying the efficiency of CO2 capture by Lewis

Jay J. Chi, Timothy C. Johnstone, Dan Voicu, Paul Mehlmann, Fabian Dielmann, Eugenia Kumacheva, Douglas W. Stephan
Chem. Sci. 2017, 8, 3270–3275 [doi:10.1039/c6sc05607e]
29. Mechanistic Studies on a Cooperative NHC Organocatalysis/Palladium Catalysis System: Uncovering Significant Lessons for Mixed Chiral Pd(NHC)(PR3) Catalyst Design
C. Guo,* D. Janssen-Müller, M. Fleige, A. Lerchen, C. G. Daniliuc, F. Glorius
J. Am. Chem. Soc. 2017, 139, 4443–4451 [doi:10.1021/jacs.7b00462]
28. Facile Modulation of FLP Properties: A Phosphinylvinyl Grignard Reagent and Ga/P- and In/P2-Based Frustrated Lewis Pairs
J. Backs, M. Lange, J. Possart, A. Wollschläger, C. Mück-Lichtenfeld, W. Uhl
Angew. Chem. Int. Ed. 2017, 56, 3094–3097 [doi:10.1002/anie.201612485]
27. NHC-Organocatalyzed CAr–O Bond Cleavage: Mild access to 2-Hydroxybenzophenones
F. Lied†, A. Lerchen†, T. Knecht, C. Mück-Lichtenfeld, F. Glorius
ACS Catal. 2016, 6, 7839–7843 [doi:10.1021/acscatal.6b02227]
26. NHC-Organocatalyzed CAr–O Bond Cleavage: Mild access to 2-Hydroxybenzophenones
D. Janssen-Müller†, S. Singha†, F. Lied, K. Gottschalk, F. Glorius
Angew. Chem., Int. Ed. 2017, 56, ASAP–ASAP [doi:10.1002/anie.201610203]
25. Employing Pd-Catalyzed C–H Arylation in Multicomponent-Multicatalyst Reactions (MC)2R: One-Pot Synthesis of Dihydrobenzoquinolines
F. Lied, H. Brodnik Žugelj, S. Kress, B. Štefane, F. Glorius, M. Lautens
ACS Catal. 2017, 7, 1378–1382 [doi:10.1021/acscatal.6b03209]
24. Donor Strength Determination of Benzoxazolin-2-ylidene, Benzobisoxazolin-2-ylidene, and Their Isocyanide Precursors by 13C NMR Spectroscopy of Their PdII and AuI Complexes
M. Meier, T. T. Y. Tan, F. E. Hahn, H. V. Huynh
Organometallics 2017, 36, 275–284 [doi:10.1021/acs.organomet.6b00736]
23. Lewis acid catalysis: catalytic hydroboration of alkynes initiated by Piers' borane
M. Fleige, J. Möbus, T. v. Stein, F. Glorius, D. W. Stephan
Chem. Commun. 2016, 52, 10830–10833 [doi:10.1039/C6CC05360B]
22. NHC-Catalyzed Enantioselective Dearomatizing Hydroacylation of Benzofurans and Benzothiophenes for the Synthesis of Spirocycles
D. Janssen-Müller, M. Fleige, D. Schlüns, M. Wollenburg, C. G. Daniliuc, J. Neugebauer, F. Glorius
ACS Catalysis 2016, 6, 5735–5739 [doi:10.1021/acscatal.6b01852]
21. Reversible Carbon Dioxide Binding by Simple Lewis Base Adducts
with Electron-Rich Phosphines
F. Buß, P. Mehlmann, C. Mück-Lichtenfeld, K. Bergander, F. Dielmann
J. Am. Chem. Soc. 2016, 138, 1840−1843 [doi:10.1021/jacs.5b13116]
20. Poly(paraphenylene sulfide) and Poly(metaphenylene sulfide) via Light-initiated SRN1-type Polymerization of Halogenated Thiophenols
N. B. Heine, A. Studer
Macrom. Rapid Commun. 2016, 37, 1494−1498 [doi:10.1002/marc.201600254]
19. Synthesis of Chiral Piperazinones Using Amphoteric Aziridine Aldehyde Dimers and Functionalized Isocyanides
N. B. Heine, S. J. Kaldas, L. Belding, O. Shmatova, T. Dudding, V. G. Nenajdenko, A. Studer, A. K. Yudin
J. Org. Chem. 2016, 81 (12), 5209–5216 [doi:10.1021/acs.joc.6b00471]
18. No Need for External Orthogonality in Subsystem Density-Functional Theory
J. P. Unsleber, J. Neugebauer, C. R. Jacob
Phys. Chem. Chem. Phys. 2016, 18, 21001−21009 [doi:10.1039/c6cp00332j]
17. Cooperative N-Heterocyclic Carbene/Palladium-Catalyzed Enantioselective Umpolung Annulations
C. Guo, M. Fleige, D. Janssen-Müller, C. G. Daniliuc, F. Glorius
J. Am. Chem. Soc. 2016, 138, 7840–7843 [doi:10.1021/jacs.6b04364]
16. Synthesis of Complexes with Abnormal "Protic" N-Heterocyclic Carbenes
H. Jin, T. T. Y. Tan, F. E. Hahn
Angew. Chem. Int. Ed. 2015, 54, 13811–13815 [doi:10.1002/anie.201507206]
15. 6-Pyrazolylpurine as an Artificial Nucleobase for Metal-Mediated Base Pairing in DNA Duplexes
J. C. Léon, I. Sinha, J. Müller
Int. J. Mol. Sci. 2016, 17, 554–564 [doi:10.3390/ijms17040554]
14. Thermodynamics of the formation of Ag(I)-mediated azole base pairs in DNA duplexes
K. Schweizer, J. C. Léon, B. J. Ravoo, J. Müller
J. Inorg. Biochem. 2016, 160, 256–263 [doi:10.1016/j.jinorgbio.2016.03.003]
13. Preparation of Rhodium(III) Di-NHC Chelate Complexes Featuring Two Different NHC Donors via a Mild NaOAc-Assisted C−H Activation
F. Aznarez, P. J. Sanz Miguel, T. T. Y. Tan, F. E. Hahn
2016, 35, 410−419 [doi:10.1021/acs.organomet.5b00993]
12. Frustrated Lewis Pair Chemistry Derived from Bulky Allenyl and Propargyl Phosphanes
C. Rosorius, J. Möricke, B. Wibbeling, A. C. McQuilken, T. H. Warren, C. G. Daniliuc, G. Kehr, G. Erker
Chem. Eur. J. 2016, 22, 1103–1113 [doi:10.1002/chem.201502493]
11. Hydrogen Activation by an Iridium(III) Complex Bearing a Bidentate Protic NH,NR-NHC∧Phosphine Ligand
S. Cepa, C. Schulte to Brinke, F. Roelfes, F. E. Hahn
Organometallics 2015, 34, 5454–5460 [doi:10.1021/acs.organomet.5b00799]
10. Selective N,O-Addition of the TEMPO Radical to Conjugated Boryldienes
F. Türkyilmaz, G. Kehr, J. Li, C. G. Daniliuc, M. Tesch, A. Studer, G. Erker
Angew. Chem. 2016, 128, 1492–1495 [doi:10.1002/ange.201509114]
9. Enamine/butadienylborane cycloaddition in the frustrated Lewis pair regime
G.-Q. Chen, F. Türkyilmaz, C. G. Danliuc, C. Bannwarth, S. Grimme, G. Kehr, G. Erker
Org. Biomol. Chem. 2015, 13, 10477–10486 [doi:10.1039/c5ob01602a]
8. A 1,1-Carboboration Route to Bora-Nazarov Systems
F. Ge, F. Türkyilmaz, C. G. Daniliuc, G. Kehr, G. Erker
Chem. Asian J. 2015, 10, 2497–2502 [doi:10.1002/asia.201500636]
7. Chalcogen Capture by an Al/P-Based Frustrated Lewis Pair: Formation of Al-E-P Bridges and Intermolecular Tellurium–Tellurium Interactions
W. Uhl, P. Wegener, M. Layh, A. Hepp, E.-U. Würthwein
2015, 34 (11), 2455–2462 [doi:10.1021/om501206p]
6. Imidazol-2-ylidenaminophosphines as Highly Electron-rich Ligands for Transition-metal Catalysts
M. A. Wünsche, P. Mehlmann, T. Witteler, F. Buß, P. Rathmann, F. Dielmann
Angew. Chem. Int. Ed. 2015, 54, 11857–11860 [doi:10.1002/anie.201504993]
5. Switchable selectivity in an NHC-catalysed dearomatizing annulation reaction
C. Guo, M. Fleige, D. Janssen-Müller, C. G. Daniliuc, F. Glorius
Nature Chem. 2015, 7, 842–847 [doi:10.1038/nchem.2337]
4. Structural Elucidation of the Bispecificity of A Domains as a Basis for Activating Non-natural Amino Acids
H. Kaljunen, S. H. H. Schiefelbein, D. Stummer, S. Kozak, R. Meijers, G. Christiansen, A. Rentmeister
Angew. Chem. Int. Ed. 2015, 54, 8833–8836 [doi:10.1002/anie.201503275]
3. Regioselectivity of the C-Metalation of 6-Furylpurine: Importance of Directing Effects
I. Sinha, A. Hepp, B. Schirmer, J. Kösters, J. Neugebauer, J. Müller
Inorg. Chem. 2015, 54, 4183–4185 [doi:10.1021/acs.inorgchem.5b00450]
2. Dual Role of Rh(III) Catalyst Enables Regioselective Halogenation of (Electron-Rich) Heterocycles
N. Schröder, F. Lied, F. Glorius
J. Am. Chem. Soc. 2015, 137, 1448–1451 [doi:10.1021/jacs.5b00283]
1. Enantioselective Intramolecular Hydroacylation of Unactivated Alkenes: An NHC-Catalyzed Robust and Versatile Formation of Cyclic Chiral Ketones
D. Janssen-Müller, M. Schedler, M. Fleige, C. G. Daniliuc, F. Glorius
Angew. Chem. 2015, 127, 12671–12675 [doi:10.1002/ange.201412302]; Angew. Chem. Int. Ed. 2015, 54, 12492–12496 [doi:10.1002/anie.201412302]

IRTG Münster-Toronto
Corrensstr. 30
· D-48149 Münster
Tel: +49 251 83-33111 · Fax: +49 251 83-33108