Beteiligung am Exzellenzcluster

CiM Principal Investigator
Mitglied der CiM-IMPRS Graduiertenschule

  • Forschungsgebiet A.3: Funktionelle Membrandomänen bei neuronaler und nicht-neuronaler Kompartimentierung
  • Projekt FF-2017-10: Biohybrid neurosynaptic chips interfaced with nanostructured, integrated optics (Jürgen Klingauf, Wolfram Pernice, Projektlaufzeit: 11/2017 - 12/2018)
  • Projekt FF-2015-05: Direct neuronal Interfacing on functionalized microstructured coverslips for imaging synapse development and plasticity (Jürgen Klingauf, Markus Missler, Projektlaufzeit: 07/2015 - 06/2017)
© CiM - Peter Grewer

„Mich begeistert das große Rätsel Gehirn“

Um die Frage zu beantworten, wie das Gehirn als Ganzes funktioniert, reicht ein Leben nicht aus. Deshalb beschäftigt sich Prof. Jürgen Klingauf mit den kleinsten Teilen des Gehirns, den Synapsen von Nervenzellen. Sein Ziel: künstliche Synapsen erzeugen und so Nervenzellen-Netzwerke bilden. Zum Interview

CiM-Publikationen

alle Publikationen von Jürgen Klingauf (PubMed)

2018

Kahms M, Klingauf J. Novel pH-Sensitive Lipid Based Exo-Endocytosis Tracers Reveal Fast Intermixing of Synaptic Vesicle Pools. Front Cell Neurosci 2018;12: 18. Abstract
Lima AM, Wegner SV, Martins Cavaco AC, Estevao-Costa MI, Sanz-Soler R, Niland S, Nosov G, Klingauf J, Spatz JP, Eble JA. The spatial molecular pattern of integrin recognition sites and their immobilization to colloidal nanobeads determine alpha2beta1 integrin-dependent platelet activation. Biomaterials 2018;167: 107-120. Abstract
Schuermann S, Steffes G, Manikowski D, Kastl P, Malkus U, Bandari S, Ohlig S, Ortmann C, Rebollido-Rios R, Otto M, Nusse H, Hoffmann D, Klambt C, Galic M, Klingauf J, Grobe K. Proteolytic processing of palmitoylated Hedgehog peptides specifies the 3-4 intervein region of the Drosophila wing. Elife 2018;7: epub. Abstract

2017

Bodzeta A, Kahms M, Klingauf J. The Presynaptic v-ATPase Reversibly Disassembles and Thereby Modulates Exocytosis but Is Not Part of the Fusion Machinery. Cell Rep 2017;20: 1348-1359. Abstract
de Vries WC, Grill D, Tesch M, Ricker A, Nusse H, Klingauf J, Studer A, Gerke V, Ravoo BJ. Reversible Stabilization of Vesicles: Redox-Responsive Polymer Nanocontainers for Intracellular Delivery. Angew Chem Int Ed Engl 2017;56: 9603-9607. Abstract
Di Russo J, Luik A-L, Yousif L, Budny S, Oberleithner H, Hofschröer V, Klingauf J, van Bavel E, Bakker E NTP, Hellstrand P, Bhattachariya A, Albinsson S, Pincet F, Hallmann R, Sorokin L. Endothelial basement membrane laminin 511 is essential for shear stress response. EMBO J 2017;36: 183-201. Abstract
Martineau M, Guzman RE, Fahlke C, Klingauf J. VGLUT1 functions as a glutamate/proton exchanger with chloride channel activity in hippocampal glutamatergic synapses. Nat Commun 2017;8: 2279. Abstract
Shah B, Lutter D, Tsytsyura Y, Glyvuk N, Sakakibara A, Klingauf J, Puschel AW. Rap1 GTPases Are Master Regulators of Neural Cell Polarity in the Developing Neocortex. Cereb Cortex 2017;27: 1253-1269. Abstract

2016

Rajappa R, Gauthier-Kemper A, Boning D, Huve J, Klingauf J. Synaptophysin 1 Clears Synaptobrevin 2 from the Presynaptic Active Zone to Prevent Short-Term Depression. Cell Rep 2016;14: 1369-1381. Abstract
Saha T, Rathmann I, Viplav A, Panzade S, Begemann I, Rasch C, Klingauf J, Matis M, Galic M. Automated analysis of filopodial length and spatially resolved protein concentration via adaptive shape tracking. Mol Biol Cell 2016;27: 3616-3626. Abstract
Shah B, Lutter D, Bochenek ML, Kato K, Tsytsyura Y, Glyvuk N, Sakakibara A, Klingauf J, Adams RH, Puschel AW. C3G/Rapgef1 Is Required in Multipolar Neurons for the Transition to a Bipolar Morphology during Cortical Development. PLoS One 2016;11: e0154174. Abstract

2015

Gauthier-Kemper A, Kahms M, Klingauf J. Restoring synaptic vesicles during compensatory endocytosis. Essays Biochem 2015;57: 121-134. Abstract
Wedeking T, Lochte S, Birkholz O, Wallenstein A, Trahe J, Klingauf J, Piehler J, You C. Spatiotemporally Controlled Reorganization of Signaling Complexes in the Plasma Membrane of Living Cells. Small 2015;11: 5912-5918. Abstract

2014

Namadurai S, Balasuriya D, Rajappa R, Wiemhofer M, Stott K, Klingauf J, Edwardson JM, Chirgadze DY, Jackson AP. Crystal structure and molecular imaging of the Nav channel beta3 subunit indicates a trimeric assembly. J Biol Chem 2014;289: 10797-10811. Abstract

2013

Hoerr V, Tuchscherr L, Huve J, Nippe N, Loser K, Glyvuk N, Tsytsyura Y, Holtkamp M, Sunderkotter C, Karst U, Klingauf J, Peters G, Loffler B, Faber C. Bacteria tracking by in vivo magnetic resonance imaging. BMC Biol 2013;11: 63. Abstract
Hua Y, Woehler A, Kahms M, Haucke V, Neher E, Klingauf J. Blocking endocytosis enhances short-term synaptic depression under conditions of normal availability of vesicles. Neuron 2013;80: 343-349. Abstract