The video shows mesenchymal stem cells (OP9) during differentiation into adipocytes (fat cells) over the course of almost 48 hours.
It was recorded with a novel holotomographic microscope, the Nanolive 3D Cell Explorer, which allows label-free nanoscopy based on the refractive index of different cell components.
The technique clearly resolves nuclei, mitochondria, as well as lipid droplets. Furthermore, a mitosis as well as an apoptosis event are shown.
Courtesy of the groups Busch and Grasshoff.