Glycosylation of adhesion molecules
PD Dr. Martin Wild
PhD projects to be supervised by Dr. Martin Wild can be designed in the area of glycosylation of adhesion molecules participating in leukocyte recruitment. The following point should be included in the proposed project:
- P-selectin glycoprotein ligand (PSGL)-1: E-selectin has two binding sites at PSGL-1. One binding site is at the N-terminal end of PSGL-1, but the second site is only poorly defined. The purpose of this project is to exactly identify the second binding site and the glycosylation enzymes that are required for E-selectin binding at this position.
