Dr. Kristin Wallmeier

Research Topics

In my studies, I research coherent Raman scattering. These are processes that are used in microscopy to identify molecules within a sample. In particular, I am working on modifying the excitation beams and also the detection of the resulting signal in order to generate low-noise and background-free microscopy images. I enjoy working on this topic because Raman microscopy has a large and rapidly developing field of application.

Publications

Research Articles (Journals)

2026

Wallmeier, Kristin, Lemberger, Nick S., and Fallnich, Carsten. 2026. “Two- and three-beam photothermal vs. conventional stimulated Raman scattering.” Applied Physics B: Lasers and Optics 132 (57). doi: 10.1007/s00340-026-08660-x.
Luna, Saara K., Kuzma, Benjamin A., Lemberger, Nick-Sydney, Wallmeier, Kristin, Fallnich, Carsten, and Evans, Conor L. 2026. “Adaptive optics stimulated Raman scattering microscopy for topical product pharmacokinetic imaging.” Biomedical Optics Express 17 (1): 125–144. doi: 10.1364/BOE.576409.
Lemberger, Nick S., Wallmeier, Kristin, and Fallnich, Carsten. 2026. “Automated correction of optical attenuation in stimulated Raman scattering imaging.” Optics Express 34 (6): 10736–10748. doi: 10.1364/OE.580899.
Wallmeier, Kristin, and Lemberger, Nick S. Fallnich Carsten. in Kürze. “Photothermal stimulated Raman scattering with two beams only.” .

2025

Lemberger, Nick S., Wallmeier, Kristin, and Fallnich, Carsten. 2025. “High-bandwidth noise-reduced absorption-corrected autobalanced detection.” Optics Express 33 (1): 62–74. doi: 10.1364/OE.540254.
Wallmeier, Kristin, Gao, Ming, Lemberger, Nick S, and Fallnich, Carsten. 2025. “Waveguide-based optical parametric oscillator for coherent Raman scattering applications.” Applied Physics B: Lasers and Optics 131 (36). doi: 10.1007/s00340-025-08397-z.
Tu, Dandan, Lemberger, Nick-Sidney, Wallmeier, Kristin, Riseman, Jackson, Kuzma, Benjamin A., Wei, Yuxiao, Khoo, Ting Chean, Rantou, Elena, Ghosh, Priyanka, Luke, Markham C., Raney, Sam G., Fallnich, Carsten, and Evans, Conor L. 2025. “Improved Dual-Modality Bioequivalence Evaluation of Topical Formulations Within Human Skin Using Stimulated Raman Scattering Microscopy.” Pharmaceutics 17 (9) 1193. doi: 10.3390/pharmaceutics17091193.

2023

Wallmeier, Kristin, Würthwein, Thomas, Lemberger, Nick, Brinkmann, Maximilian, Hellwig, Tim, and Fallnich, Carsten. 2023. “Frequency modulation stimulated Raman scattering scheme for real-time background correction with a single light source.” Biomedical Optics Express 14 (1): 315–325. doi: 10.1364/BOE.476513.

2021

Würthwein, Thomas, Brinkmann, Maximilian, Hellwig, Tim, Wallmeier, Kristin, and Fallnich, Carsten. 2021. “High-sensitivity frequency modulation CARS with a compact and fast tunable fiber-based light source.” Optics Letters 46 (15): 3544–3547. doi: 10.1364/OL.425578.
Würthwein, Thomas, Wallmeier, Kristin, Brinkmann, Maximilian, Hellwig, Tim, Lüpken, Niklas M., Lemberger, Nick S., and Fallnich, Carsten. 2021. “Multi-color stimulated Raman scattering with a frame-to-frame wavelength-tunable fiber-based light source.” Biomedical Optics Express 12 (10): 6228–6236. doi: 10.1364/BOE.436299.

Conference Contributions

Research Articles in Edited Proceedings (Conferences)

2026

Khoo, Ting Chean Luna Saara K., Lemberger, Nick-Sydney, Wallmeier, Kristin, Fallnich, Carsten, and Evans, Conor L. in Kürze. “Signal correction of stimulated Raman scattering (SRS) signal loss from skin structure and drug application.” in Visualizing and Quantifying Drug Distribution in Tissue X, edited by Conor L. Evans and Kin Foong Chan. San Francisco.

2025

Wallmeier, Kristin, Gao, Ming, and Fallnich, Carsten. 2025. “Waveguide-based optical parametric oscillator for coherent Raman scattering spectroscopy and microscopy.” in Proceedings of SPIE Photonics West 13332, edited by SPIE. San Francisco: SPIE. doi: 10.1117/12.3041867.
Lemberger, Nick S., Wallmeier, Kristin, and Fallnich, Carsten. 2025. “High-bandwidth noise-reduced absorption-corrected autobalanced detection for stimulated Raman scattering microscopy.” in Proceedings of SPIE Photonics West, 13332, edited by SPIE. San Francisco: SPIE. doi: 10.1117/12.3041877.
Lemberger, Nick S., Wallmeier, Kristin, and Fallnich, Carsten. in Kürze. “Towards fully loss-corrected SRS imaging.” in Proceedings of CLEO Europe/EQEC 2025
Fallnich, Carsten, Wallmeier, Kristin, Gao, Ming, Lemberger, Nick-Sidney, Timmerkamp, Maximilian, and Lüpken, Niklas M. 2025. “A route to chip-based ultrafast light sources for coherent Raman imaging.” Preprint. in Proceedings of 838. Wilhelm und Else Heraeus-Seminar, edited by Wilhelm und Else Heraeus-Stiftung. Bad Honnef: Wilhelm und Else Heraeus-Stiftung.

2024

Tu, Dandan, Lemberger, Nick Sidney, Wallmeier, Kristin, Riseman, Jackson, Kuzma, Benjamin A., Wei, Yuxiao, Khoo, Ting Chean, Ghosh, Priyanka, Raney, Sam G., Luke, Markham C., Fallnich, Carsten, and Evans, Conor L. 2024. “Dual modality monitoring of topical formulations within human skin using stimulated Raman scattering (SRS) microscope.” in Proc. SPIE PC12821, edited by SPIE. San Francisco: SPIE. doi: 10.1117/12.3001122.
Wallmeier, Kristin, Lüpken, Niklas M., Würthwein, Thomas, and Fallnich, Carsten. 2024. “Simplified and improved heterodyne coherent anti-Stokes Raman scattering for background correction.” in Proc. SPIE 12855, edited by SPIE. San Francisco: SPIE. doi: 10.1117/12.3000288.
Gao, Ming, Wallmeier, Kristin, and Fallnich, Carsten. 2024. “Waveguide-based optical parametric oscillator for coherent anti-Stokes Raman scattering.” in 11TH EPS-QEOD EUROPHOTON CONFERENCE, edited by Andrejus Michailovas, Jacob Mackenzie, Federico Pirzio and Eric. Cormier. Vilnius: EPJ Web of Conferences. doi: 10.1051/epjconf/202430702012.

2023

Wallmeier, Kristin, Würthwein, Thomas, Hellwig, Tim, Brinkmann, Maximilian, Lemberger, Nick, and Fallnich, Carsten. 2023. “Simplified FM SRS for up to 8.3-fold contrast improvement.” in Proceedings on the Focus on Microscopy 2023, edited by Focus on Microscopy. Porto: Focus on Microscopy.
Wallmeier, Kristin, Würthwein, Thomas, Hellwig, Tim, Brinkmann, Maximilian, Lemberger, Nick, and Fallnich, Carsten. 2023. “Single-source FM SRS with pixel-to-pixel contrast improvement.” in 2023 Conference on Lasers and Electro-Optics Europe & European Quantum Electronics Conference (CLEO/Europe-EQEC), edited by IEEE. München: Wiley-IEEE Press. doi: 10.1109/CLEO/Europe-EQEC57999.2023.10232588.
Wallmeier, Kristin, Würthwein, Thomas, Hellwig, Tim, Brinkmann, Maximilian, Lemberger, Nick, and Fallnich, Carsten. 2023. “Single low-noise fiber-based light source for FM SRS.” in Proceedings of RamanFest 2023, edited by Phantoms Foundation. Paris: Phantoms Foundation.
Lemberger, Nick, Wallmeier, Kristin, and Fallnich, Carsten. 2023. “A pixel-by-pixel correcting autobalanced detector for SRS microscopy.” in Proceedings of RamanFest 2023, edited by Phantoms Foundation. Paris: Phantoms Foundation.

2022

Kuzma, Benjamin, Würthwein, Thomas, Lemberger, Nick S. Wallmeier Kristin, Fallnich, Carsten, Evans, Conor L., Troensegaard Nielsen, Kim, Bastholm Jensen, Louise, Svensson, Lars, and Tran, Jean-Luc. 2022. “Cutaneous pharmacokinetics of escalating Ruxolitinib formulation doses utilizing a coherent Raman imaging pipeline.” in Proceedings Volume PC11938, edited by SPIE. San Francisco: SPIE.
Wallmeier, Kristin, Würthwein, Thomas, Hellwig, Tim, Brinkmann, Maximilian, Lemberger, Nick, and Fallnich, Carsten. 2022. “Simplified FM CARS and FM SRS with up to 18-fold contrast improvement.” in Proceedings of the 27th International Conference on Raman Spectroscopy, edited by International Conference on Raman Spectroscopy. Long Beach: Materials Research Society.
Wallmeier, Kristin, Würthwein, Thomas, Brinkmann, Maximilian, Hellwig, Tim, and Fallnich, Carsten. 2022. “Fiber-based light source with multi-color output and fast wavelength tuning.” in EPJ Web Conf. 267, edited by P. Helfenstein. Hannover: EDP Sciences. doi: 10.1051/epjconf/202226702012.

2021

Brinkmann, Maximilian, Hellwig, Tim, Würthwein, Thomas, Wallmeier, Kristin, Lemberger, Nick S., and Fallnich, Carsten. 2021. “Multicolor Stimulated Raman Scattering Microscopy with a Widely Tunable Fiber Laser.” in OSA Technical Digest, edited by Optica Publishing Group. München: Optica.
Brinkmann, Maximilian, Würthwein, Thomas, Hellwig, Tim, Wallmeier, Kristin, Dobner, Sven, and Fallnich, Carsten. 2021. “Enhanced Sensitivity of Coherent Raman Imaging by a Frequency Modulated Portable Light Source.” in Proceedings on the Focus on Microscopy, edited by Focus on Microscopy. Porto: Focus on Microscopy.
Brinkmann, Maxilimian, Hellwig, Tim, Würthwein, Thomas, Lemberger, Nick S., Wallmeier, Kristin, and Fallnich, Carsten. 2021. “Multicolor Stimulated Raman Scattering Microscopy with a Widely Tunable Portable Light Source.” in Proceedings of the Focus on Microscopy 2021, edited by Focus on Microscopy. Porto: Focus on Microscopy.
Brinkmann, Maximilian, Würthwein, Thomas, Hellwig, Tim, Wallmeier, Kristin, and Fallnich, Carsten. 2021. “Frequency-Modulated Portable Light Source for Coherent Raman Imaging with Enhanced Sensitivity.” in OSA Technical Digest, edited by Optica Publishing Group. München: Optica.

Abstracts in Digital Collections (Conferences)

2025

Lemberger, Nick S., Wallmeier, Kristin, and Fallnich, Carsten. 2025. “Amplitude-to-phase detection scheme for improved signal-to-noise ratio in stimulated Raman scattering.” in Proceedings of Photonics West 2025
Wallmeier, Kristin, Lemberger, Nick S., and Fallnich, Carsten. in Kürze. “Aperture-less stimulated Raman photothermal microscopy in epi-configuration.” Preprint. contribution to the CLEO Europe/EQEC, München
Wallmeier, Kristin, Lemberger, Nick, and Fallnich, Carsten. 2025. “Epi-detected stimulated Raman photothermal microscopy.” Preprint. contribution to the 838. WE-Heraeus-Seminar: Manipulating Molecular Electronic Properties by Vibrational Excitations: Novel Spectroscopies and Microscopies, Bad Honnef , edited by Bredenbeck Jens and Xiong Wei.
Lemberger, Nick-Sidney, Wallmeier, Kristin, and Fallnich, Carsten. 2025. “Special detector design for improved SRS imaging.” Preprint. contribution to the 838. WE-Heraeus-Seminar: Manipulating Molecular Electronic Properties by Vibrational Excitations: Novel Spectroscopies and Microscopies, Bad Honnef

2024

Wallmeier, Kristin, Lüpken, Niklas M., Würthwein, Thomas, and Fallnich, Carsten. 2024. “Simple and phase-stabilized setup for heterodyne anti-Stokes Raman scattering microscopy.” contribution to the Focus on Microscopy, Genua
Lemberger, Nick S., Wallmeier, Kristin, and Fallnich, Carsten. 2024. “A pixel-by-pixel correcting autobalanced detector for SRS microscopy.” contribution to the Focus on Microscopy, Genua

2023

Wallmeier, Kristin, Würthwein, Thomas, Hellwig, Tim, Brinkmann, Maximilian, Lemberger, Nick, and Fallnich, Carsten. 2023. “Single low-noise fiber-based light source for FM SRS.” contribution to the RamanFest 2023, Paris
Lemberger, Nick, Wallmeier, Kristin, and Fallnich, Carsten. 2023. “A pixel-by-pixel correcting autobalanced detector for SRS microscopy.” contribution to the RamanFest 2023, Paris

2022

Wallmeier, Kristin, Hellwig, Tim, Brinkmann, Maximilian, and Fallnich, Carsten. 2022. “Frequency modulation CARS imaging with a fiber optical parametric oscillator.” contribution to the International Conference on Raman Spectroscopy, Long Beach, Kalifornien

Scientific Talk

Wallmeier, Kristin 2023: “Simplified frequency modulation SRS (and frequency modulation CARS) for contrast improvement”. Seminar "Photochemie und Femtosekundenspektroskopie", Heinrich Heine Universität Düsseldorf, Düsseldorf, Jun 15, 2023.