Forschungsschwerpunkte
Mykotoxine
Identifizierung und Quantifizierung von Mykotoxinen in Lebensmitteln und Umweltproben. Einfluss der Lebensmittelverarbeitung auf Mykotoxine.
Prozesskontaminanten
Bildung und Minimierung von Prozesskontaminanten wie Furanen, Monochlorpropandiolen (MCPDs), Glycidolen und Acrylamid
Humanes Biomonitoring
Humanes Biomonitoring von Mykotoxinen und Prozesskontaminanten sowie Expositionsabschätzung.
Instrumentelle Analytik (HPLC-MS/MS, HPLC-HRMS, GC-MS)
Entwicklung von neuen Massenspektrometrie-basierten Analysenmethoden.
Vita
Akademische Ausbildung
- Kollegiat der International Research Training Group Münster/D - Nagoya/J (IRTG-MS/NG)
- Dissertation (Prof. Dr. H.-U. Humpf), Lehrstuhl für Lebensmittelchemie der WWU Münster
- Forschungsaufenthalt an der Nagoya University, Nagoya, Japan, Department of Chemistry (Prof. Dr. D. Uemura)
Beruflicher Werdegang
- Akademischer Rat am Institut für Lebensmittelchemie der Universität Münster, Leiter der Serviceeinheit "Instrumentelle Analytik"
- Post-Doc am Institut für Lebensmittelchemie der WWU Münster (Prof. Dr. H.-U. Humpf)
Preise
- Stockmeyer Wissenschaftspreis – Heinrich-Stockmeyer-Stiftung
Mitgliedschaften und Aktivitäten in Gremien
- Deutsches Institut für Normung (DIN) (NA 057-01-14 AA "Prozesskontaminanten", Mitglied)
- Gesellschaft für Mykotoxinforschung e.V. (Schatzmeister)
- Mitglied im Editorial Board der Zeitschrift "Mycotoxin Research"
- Mitglied der §64-LFGB Arbeitssgruppe "Mykotoxine" beim Bundesamt für Verbraucherschutz und Lebensmittelsicherheit
Lehre
- Seminar: Instrumentelle Analytik [124225]
- [ – | Mo., – | | LC 3]
- [ – | Fr., – | | LC 3]
- Seminar: Institutsseminar [124233]
(zusammen mit Florian Hübner, Hans-Ulrich Humpf, Melanie Esselen und Matthias Behrens)- [Do., – | ]
- Seminar: Aktuelle Forschung [124229]
(zusammen mit Florian Hübner, Hans-Ulrich Humpf, Melanie Esselen und Matthias Behrens)- [ – | Do., – | | LC 1]
- Praktikum: Instrumentelles Messtechnikpraktikum [124226]
- Vortrag: Vortrag zur Bachelorarbeit [124219]
(zusammen mit Michael Lange-Aperdannier, Hans-Ulrich Humpf, Florian Hübner, Melanie Esselen und Matthias Behrens)- [ – | Einzeltermin]
- Seminar: Aktuelle Forschung
(zusammen mit Florian Hübner, Hans-Ulrich Humpf, Melanie Esselen und Matthias Behrens)- Seminar: Instrumentelle Lebensmittel- und Futtermittelanalytik
- Seminar: Institutsseminar
(zusammen mit Florian Hübner, Hans-Ulrich Humpf, Melanie Esselen und Matthias Behrens)- Praktikum: Instrumentelle Lebensmittel- und Futtermittelanalytik
(zusammen mit Florian Hübner)
Publikationen
- Lipinski, S, Becker, M, Lindekamp, N, Humpf, H, und Cramer, B. . „Formation of Furan, Alkylfurans and Acrylamide during Breakfast Cereal Manufacturing: Comparison of Model Experiments with Industrial Processes.“ Preprint. Food Control 179: 111598.. doi: 10.1016/j.foodcont.2025.111598.
- Cramer, B, Bahlmann, A, DeRosa, M, Kodikara, C, Malone, R, Steiner, D, Suman, M, Sumarah, M, und Tittlemier, S. . „Developments in mycotoxin analysis: an update for 2024-2025.“ World Mycotoxin Journal 19 (1): 3–35. doi: 10.1163/18750796-bja10035.
- Phillips, E., Ngure, F.M., Kassim, N., Turner, P.C., Makule, E., Smith, L.E., Makori, N., Cramer, B., Humpf, H.-U., Nelson, R.J., und Stoltzfus, R.J. . „The effect of an intervention to reduce aflatoxin consumption from 6 to 18 mo of age on length-for-age z-scores in rural Tanzania: a cluster-randomized trial.“ American Journal of Clinical Nutrition 121 (2): 333–342. doi: 10.1016/j.ajcnut.2024.11.022.
- Lipinski, Sarah, Becker, Marlen, Meyer, Jens Chr., Nowakowski, Christine, Humpf, Hans-Ulrich, und Cramer, Benedikt. . „Impact of Physicochemical Parameters on the Furan, Alkylfuran, and Acrylamide Formation during Extrusion Cooking of Breakfast Cereals.“ ACS Food Science & Technology 2025. doi: 10.1021/acsfoodscitech.4c00727.
- Kelman, M.J., Renaud, J.B., McCarron, P., Hoogstra, S., Chow, W., Wang, J., Varga, E., Patriarca, A., Medina Vaya, A., Visintin, L., Nguyen, T., De Boevre, M., De Saeger, S., Karanghat, V., Vuckovic, D., McMullin, D.R.Dall' Asta C. Ayeni K., Warth, B., Huang, M., Tittlemier, S., Mats, L., Cao, R., Sulyok, M., Xu, K., Berthiller, F., Kuhn, M., Cramer, B., Ciasca, B., Lattanzio, V., De Baere, S., Croubels, S., DesRochers, N., Sura, S., Bates, J., Wright, E.J., Thapa, I., Blackwell, B.A., Zhang, K., Wong, J., Burns, L., Borts, D.J., und Sumarah, M.W. . „International interlaboratory study to normalize liquid chromatography-based mycotoxin retention times through implementation of a retention index system.“ Journal of Chromatography A 1745: 465732.. doi: 10.1016/j.chroma.2025.465732.
- Zinßius, L, Keuter, L, Krischek, C, Jessberger, N, Cramer, B, und Plötz, M. . „Influence of the β-Casein Genotype of Cow’s Milk (A1, A2) on the Quality and $β$-Casomorphin-7 (BCM-7) Content of a Semi-Hard Cheese During Production.“ Foods 14 (3): 463–463. doi: 10.3390/foods14030463.
- Brückner, L, Neuendorff, F, Hadenfeldt, K, Behrens, M, Cramer, B, und Humpf, H. . „Thermal Stability and Matrix Binding of Citrinin in the Thermal Processing of Starch-Rich Foods.“ Toxins 17 (2): 86–86. doi: 10.3390/toxins17020086.
- Tittlemier, S, Cramer, B, DeRosa, M, Dzuman, Z, Kodikara, C, Malone, R, Maragos, C, Suman, M, und Sumarah, M. . „Developments in analytical techniques for mycotoxin determination: an update for 2023-24.“ World Mycotoxin Journal 18 (1): 3–30. doi: 10.1163/18750796-BJA10013.
- Cramer, Benedikt, Visintin, Lia, Elias, Maris, Michael, Kuhn, H., Degen Gisela, Turner, Paul C., Humpf, Hans-Ulrich, und De Saeger, Sarah. . „Human biomonitoring of mycotoxins: key challenges and future directions.“ Mycotoxin Research 42 (1) 13. doi: 10.1007/s12550-025-00612-2.
- Moretti, Antonio, Loi, Martina, Lippolis, Vincenzo, De Girolamo, Annalisa, Fanelli, Francesca, und Cramer, Benedikt. . „From climate change to analytical advances on mycotoxin research: key insights from the 46th Mycotoxin Workshop.“ Mycotoxin Research 42 (1). doi: 10.1007/s12550-025-00629-7.
- Kuhn, Michael, Kyei, Nicholas N.A., Cramer, Benedikt, und Humpf, Hans-Ulrich. . „Online solid phase extraction-LC-MS/MS with two step peak focusing for sensitive multi-analyte analysis of mycotoxins in urine.“ Microchemical Journal 219 115821. doi: 10.1016/j.microc.2025.115821.
- Witzel, K, Djalali, Farahani-Kofoet R, Döll, S, Lindemann, V, Cramer, B, Humpf, H, und Zrenner, R. . „Metabolomics and dual proteomics identify contrasting patterns of major pathways affected in asparagus shoot upon Fusarium infection.“ Plant and Soil 2024. doi: 10.1007/s11104-024-07069-9.
- Modrzewska, M., Popowski, D., Błaszczyk, L., Stępień, Ł., Urbaniak, M., Bryła, M., Cramer, B., Humpf, H.-U., und Twarużek, M. . „Antagonistic properties against Fusarium sporotrichioides and glycosylation of HT-2 and T-2 toxins by selected Trichoderma strains.“ Scientific Reports 14 (1). doi: 10.1038/s41598-024-55920-x.
- Hassan, R., Gerdemann, A., Cramer, B., Hobloss, Z., Myllys, M., González, D., Albrecht, W., Veerkamp, J., Friebel, A., Hoehme, S., Esselen, M., Degen, G., Humpf, H., Hengstler, J., und Ghallab, A. . „Integrated data from intravital imaging and HPLC–MS/MS analysis reveal large interspecies differences in AFB1 metabolism in mice and rats.“ Archives of Toxicology 98 (4): 1081–1093. doi: 10.1007/s00204-024-03688-4.
- Pierzgalski, A., Bryła, M., B., Cramerm, Humpf, H.-U., und Twarużek, M. . „Co-occurrence of T-2 and HT-2 Mycotoxins and α and β Anomers of Their Glucosides in Wheat and Oat Grains.“ Journal of Agricultural and Food Chemistry 72 (6): 3150–3159. doi: 10.1021/acs.jafc.3c07465.
- Pierzgalski, Adam, Bryla, Marcin, Cramer, Benedikt, Humpf, Hans-Ulrich, und Twaruzek, Magdalena. . „Co-occurrence of T-2 and HT-2 Mycotoxins and α and <i>β</i> Anomers of Their Glucosides in Wheat and Oat Grains.“ Journal of Agricultural and Food Chemistry 72 (6). doi: 10.1021/acs.jafc.3c07465.
- Hassan, Reham, Gerdemann, Andrea, Cramer, Benedikt, Hobloss, Zaynab, Myllys, Maiju, Gonzalez, Daniela, Albrecht, Wiebke, Veerkamp, Jannik, Friebel, Adrian, Hoehme, Stefan, Esselen, Melanie, Degen, Gisela H., Humpf, Hans-Ulrich, Hengstler, Jan G., und Ghallab, Ahmed. . „Integrated data from intravital imaging and HPLC-MS/MS analysis reveal large interspecies differences in AFB1 metabolism in mice and rats.“ Archives of Toxicology 1. doi: 10.1007/s00204-024-03688-4.
- Kuhn, Michael, Hassan, Reham, Gonzalez, Daniela, Myllys, Maiju, Hobloss, Zaynab, Degen, Gisela H., Humpf, Hans-Ulrich, Hengstler, Jan G., Cramer, Benedikt, und Ghallab, Ahmed. . „Role of albumin in the metabolism and excretion of ochratoxin A.“ Mycotoxin Research 1. doi: 10.1007/s12550-024-00538-1.
- Brückner, Lea, Cramer, Benedikt, und Humpf, Hans-Ulrich. . „Reactions of citrinin with amino compounds modelling thermal food processing.“ Mycotoxin Research 40 (4): 709–720. doi: 10.1007/s12550-024-00557-y.
- Varga, Elisabeth, Marko, Doris, Meyer, Karsten, Cramer, Benedikt, Humpf, Hans-Ulrich, und Plötz, Madeleine. . „Vienna, the ‘City of Music’, meets mycotoxin research at the 45th Mycotoxin Workshop.“ Mycotoxin Research 40 (3): 327–329. doi: 10.1007/s12550-024-00542-5.
- Tittlemier, S., Cramer, B., De Rosa, M., Dzuman, Z., Malone, R., Maragos, C., Suman, M., und Sumarah, M. . „Developments in analytical techniques for mycotoxin determination: an update for 2022-23.“ World Mycotoxin Journal 17 (1): 3–26. doi: 10.1163/18750796-bja10002.
- Gerdemann, A, Cramer, B, Degen, GH, Veerkamp, J, Günther, G, Albrecht, W, Behrens, M, Esselen, M, Ghallab, A, Hengstler, JG, und Humpf, H-U. . „Comparative metabolism of aflatoxin B1 in mouse, rat and human primary hepatocytes using HPLC–MS/MS.“ Archives of Toxicology 97 (12): 3179–3196. doi: 10.1007/s00204-023-03607-z.
- Nikmaram, N., Brückner, L., Cramer, B., Humpf, H.-U., und Keener, K. . „Degradation products of aflatoxin M1 (AFM1) formed by high voltage atmospheric cold plasma (HVACP) treatment.“ Toxicon 230. doi: 10.1016/j.toxicon.2023.107160.
- Lipinski, S., Lindekamp, N., Funck, N., Cramer, B., und Humpf, H.-U. . „Determination of furan and alkylfuran in breakfast cereals from the European market and their correlation with acrylamide levels.“ European Food Research and Technology 2023. doi: 10.1007/s00217-023-04374-y.
- Tittlemier, S.A., Cramer, B., DeRosa, M.C., Lattanzio, V.M.T., Malone, R., Maragos, C., Stranska, M., und Sumarah, M.W. . „Developments in mycotoxin analysis: an update for 2021-22.“ World Mycotoxin Journal 16 (1): 3–24. doi: 10.3920/WMJ2022.2822.
- Kyei, N.N.A., Waid, J.L., Ali, N., Cramer, B., Humpf, H.-U., und Gabrysch, S. . „Maternal exposure to multiple mycotoxins and adverse pregnancy outcomes: a prospective cohort study in rural Bangladesh.“ Archives of Toxicology 97 (6): 1795–1812. doi: 10.1007/s00204-023-03491-7.
- Kyei, N.N.A., Cramer, B.Humpf H.-U., Degen, G.H., Ali, N., und Gabrysch, S. . „Assessment of multiple mycotoxin exposure and its association with food consumption: a human biomonitoring study in a pregnant cohort in rural Bangladesh.“ Archives of Toxicology 96 (7): 2123–2138. doi: 10.1007/s00204-022-03288-0.
- Lindemann, V, Schleiner, T, Maier, U, Fels, H, Cramer, B, und Humpf, HU. . „Analysis of mold and mycotoxins in naturally infested indoor building materials.“ Mycotoxin Research 2022. doi: 10.1007/s12550-022-00461-3.
- Puel, O, Cramer, B., Oswald, I.P., und Humpf, H.-U. . „From the laboratory bench to the lecture hall: latest findings from mycotoxin research presented at the 43rd Mycotoxin Workshop.“ Mycotoxin Research 2022. doi: 10.1007/s12550-022-00462-2.
- Tittlemier, S.A., Cramer, B., Dall'Asta, C., DeRosa, M.C., Lattanzio, V.M.T., Malone, R., Maragos, C., Stranska, M., und Sumarah, M.W. . „Developments in mycotoxin analysis: an update for 2020-2021.“ World Mycotoxin Journal 15 (1): 3–25. doi: 10.3920/WMJ2021.2752.
- Penczynski, K, Cramer, B, Dietrich, S, Humpf, H, Abraham, K, und Weikert, C. . „Mycotoxins in Serum and 24-h Urine of Vegans and Omnivores from the Risks and Benefits of a Vegan Diet (RBVD) Study.“ Molecular Nutrition and Food Research 66 (6). doi: 10.1002/mnfr.202100874.
- Lindemann, V, Schmidt, J, Cramer, B, und Humpf, H. . „Detection of Mycotoxins in Highly Matrix-Loaded House-Dust Samples by QTOF-HRMS, IM-QTOF-HRMS, and TQMS: Advantages and Disadvantages.“ Analytical Chemistry 94 (10): 4209–4217. doi: 10.1021/acs.analchem.1c04254.
- Rehagel, C, Akineden, Ö, Geisen, R, Cramer, B, Plötz, M, und Usleber, E. . „Development and application of a competitive enzyme immunoassay for the detection of penitrem A in fungal mycelium: Evidence for frequent occurrence of multiple indole-containing mycotoxins in mouldy foods.“ Food Control 132: 108558. doi: 10.1016/j.foodcont.2021.108558.
- R., Hassan, A., Friebel, L., Brackhagen, Z., Hobloss, M., Myllys, D., González, W., Albrecht, E.S.I., Mohammed, A.l., Seddek, R., Marchan, C., Cadenas, B., Cramer, H.U., Humpf, L., Hartl, B., Simbrunner, T., Reiberger, M., Trauner, S., Hoehme, G.H., Degen, J.G., Hengstler, und A., Ghallab. . „Hypoalbuminemia affects the spatio-temporal tissue distribution of ochratoxin A in liver and kidneys: consequences for organ toxicity.“ Archives of Toxicology 96 (11): 2967–2981. doi: 10.1007/s00204-022-03361-8.
- R., Hassan, D., González, Z., Hobloss, L., Brackhagen, M., Myllys, A., Friebel, A.l., Seddek, R., Marchan, B., Cramer, H.U., Humpf, S., Hoehme, G.H., Degen, J.G., Hengstler, und A., Ghallab. . „Inhibition of cytochrome P450 enhances the nephro- and hepatotoxicity of ochratoxin A.“ Archives of Toxicology 96 (12): 3349–3361. doi: 10.1007/s00204-022-03395-y.
- Hermes, L, Römermann, J, Cramer, B, und Esselen, M. . „Quantitative Analysis of β-Asarone Derivatives in <i>Acorus calamus</i> and Herbal Food Products by HPLC-MS/MS.“ Journal of Agricultural and Food Chemistry 69 (2): 776–782. doi: 10.1021/acs.jafc.0c05513.
- Hermes, L, Römermann, J, Cramer, B, und Esselen, M. . „Quantitative Analysis of β-Asarone Derivatives in Acorus calamus and Herbal Food Products by HPLC-MS/MS.“ Journal of Agricultural and Food Chemistry Online ahead of print. doi: 10.1021/acs.jafc.0c05513.
- Kalinina, S, Cramer, B, und Humpf, H. . „Current and future perspectives of mycotoxin research — report from the 42nd Mycotoxin Workshop (Online conference).“ Mycotoxin Research 37 (4): 275–278. doi: 10.1007/s12550-021-00439-7.
- Hermes, Lena, Römermann, Jannis, Cramer, Benedikt, und Esselen, Melanie. . „Phase II metabolism of asarone isomers in vitro and in humans using HPLC-MS/MS and HPLC-QToF/MS.“ Foods 10 (9): 2032.. doi: 10.3390/foods10092032.
- Schmidt, J, Cramer, B, Turner, PC, Stoltzfus, RJ, Humphrey, JH, Smith, LE, und Humpf, H-. . „Determination of urinary mycotoxin biomarkers using a sensitive online solid phase extraction‐uhplc‐ms/ms method.“ Toxins 13 (6). doi: 10.3390/toxins13060418.
- Schmidt, J, Lindemann, V, Olsen, M, Cramer, B, und Humpf, H-U. . „Dried urine spots as sampling technique for multi-mycotoxin analysis in human urine.“ Mycotoxin Research 37 (2): 129–140. doi: 10.1007/s12550-021-00423-1.
- Ghallab, A, Hassan, R, Myllys, M, Albrecht, W, Friebel, A, Hoehme, S, Hofmann, U, Seddek, A-, Braeuning, A, Kuepfer, L, Cramer, B, Humpf, H-, Boor, P, Degen, GH, und Hengstler, JG. . „Subcellular spatio-temporal intravital kinetics of aflatoxin B1 and ochratoxin A in liver and kidney.“ Archives of Toxicology 95 (6): 2163–2177. doi: 10.1007/s00204-021-03073-5.
- Tittlemier, S., Brunkhorst, J., Cramer, B., DeRosa, M., Lattanzio, V., Malone, R., Maragos, C., Stranska, M., und Sumarah, M. . „Developments in mycotoxin analysis: An update for 2019-2020.“ World Mycotoxin Journal 14 (1): 3 – 26–3 – 26. doi: 10.3920/WMJ2020.2664.
- Jagels, A, Stephan, F, Ernst, S, Lindemann, V, Cramer, B, Hübner, F, und Humpf, H-U. . „Artificial vs natural Stachybotrys infestation—Comparison of mycotoxin production on various building materials.“ Indoor Air 30 (6): 1268–1282. doi: 10.1111/ina.12705.
- Tittlemier, SA, Cramer, B, Dall'Asta, C, Iha, MH, Lattanzio, VMT, Maragos, C, Solfrizzo, M, Stranska, M, Stroka, J, und Sumarah, M. . „Developments in mycotoxin analysis: An update for 2018-19.“ World Mycotoxin Journal 13 (1): 3–24. doi: 10.3920/WMJ2019.2535.
- Warensjö, Lemming E, Montano, Montes A, Schmidt, J, Cramer, B, Humpf, H-, Moraeus, L, und Olsen, M. . „Mycotoxins in blood and urine of Swedish adolescents—possible associations to food intake and other background characteristics.“ Mycotoxin Research 36 (2): 193–206. doi: 10.1007/s12550-019-00381-9.
- Sueck, F, Hemp, V, Specht, J, Torres, O, Cramer, B, und Humpf, H-U. . „Occurrence of the ochratoxin A degradation product 2′R-ochratoxin a in coffee and other food: An update.“ Toxins 11 (6): 329.. doi: 10.3390/toxins11060329.
- Kuchenbuch, HS, Cramer, B, und Humpf, H-U. . „Matrix binding of T-2 toxin: structure elucidation of reaction products and indications on the fate of a relevant food-borne toxin during heating.“ Mycotoxin Research 35 (3): 261–270. doi: 10.1007/s12550-019-00350-2.
- Sueck, F, Cramer, B, Czeschinski, P, und Humpf, H-. . „Human Study on the Kinetics of 2′R-Ochratoxin A in the Blood of Coffee Drinkers.“ Molecular Nutrition and Food Research 63 (4): 1801026.. doi: 10.1002/mnfr.201801026.
- Kuchenbuch, HS, Schulz, M, Becker, S, Cramer, B, und Humpf, H-. . ACS Symposium Series, Bd. 1306, Thermal reactions and the formation of degradation products of T-2 and HT-2 toxin during processing of oats American Chemical Society. doi: 10.1021/bk-2019-1306.ch007.
- Sueck, F, Specht, J, Cramer, B, und Humpf, H-. . „Identification of ochratoxin-N-acetyl-L-cysteine as a new ochratoxin A metabolite and potential biomarker in human urine.“ Mycotoxin Research 2020 (36): 1–10. doi: 10.1007/s12550-019-00360-0.
- Jagels, A, Lindemann, V, Ulrich, S, Gottschalk, C, Cramer, B, Hübner, F, Gareis, M, und Humpf, H-U. . „Exploring secondary metabolite profiles of stachybotrys spp. By LC-MS/MS.“ Toxins 11 (3): 133.. doi: 10.3390/toxins11030133.
- Tittlemier, SA, Cramer, B, Dall'Asta, C, Iha, MH, Lattanzio, VMT, Malone, RJ, Maragos, C, Solfrizzo, M, Stranska-Zachariasova, M, und Stroka, J. . „Developments in mycotoxin analysis: An update for 2017-2018.“ World Mycotoxin Journal 12 (1): 3–29. doi: 10.3920/WMJ2018.2398.
- Kuchenbuch, Henning S., Becker, Stefanie, Schulz, Mareike, Cramer, Benedikt, und Humpf, Hans-Ulrich. . „Thermal stability of T-2 and HT-2 toxins during biscuit- and crunchy muesli-making and roasting.“ Food Additives and Contaminants: Part A: Chemistry, Analysis, Control, Exposure and Risk Assessment 35: 2158–2167. doi: 10.1080/19440049.2018.1530456.
- Andreeßen, C., Wolf, N., Cramer, B., Humpf, H., und Steinbüchel, A. . „In vitro biosynthesis of 3-mercaptolactate by lactate dehydrogenases.“ Enzyme and Microbial Technology 108 (null): 1–10. doi: 10.1016/j.enzmictec.2017.08.005.
- Kalinina, SA, Kalinin, DV, Hövelmann, Y, Daniliuc, CG, Mück-Lichtenfeld, C, Cramer, B, und Humpf, H. . „Auranthine, a Benzodiazepinone from Penicillium aurantiogriseum: Refined Structure, Absolute Configuration, and Cytotoxicity.“ Journal of Natural Products 81 (10): 2177–2186. doi: 10.1021/acs.jnatprod.8b00187.
- Sueck, F, Poór, M, Faisal, Z, Gertzen, C, Cramer, B, Lemli, B, Kunsági-Máté, S, Gohlke, H, und Humpf, H-U. . „Interaction of ochratoxin A and its thermal degradation product 2'R-ochratoxin A with human serum albumin.“ Toxins 10 (7). doi: 10.3390/toxins10070256.
- Schmidt, HS, Schulz, M, Focke, C, Becker, S, Cramer, B, und Humpf, H-U. . „Glucosylation of T-2 and HT-2 toxins using biotransformation and chemical synthesis: Preparation, stereochemistry, and stability.“ Mycotoxin Research 34 (3): 159–172. doi: 10.1007/s12550-018-0310-9.
- Kalinina, SA, Jagels, A, Hickert, S, Mauriz, Marques LM, Cramer, B, und Humpf, H. . „Detection of the Cytotoxic Penitrems A-F in Cheese from the European Single Market by HPLC-MS/MS.“ Journal of Agricultural and Food Chemistry 66 (5): 1264–1269. doi: 10.1021/acs.jafc.7b06001.
- Faisal, Z, Derdák, D, Lemli, B, Kunsági-Máté, S, Bálint, M, Hetényi, C, Csepregi, R, Kőszegi, T, Sueck, F, Cramer, B, Humpf, H, und Poór, M. . „Interaction of 2'R-ochratoxin A with serum albumins: Binding site, effects of site markers, thermodynamics, species differences of albumin-binding, and influence of albumin on its toxicity in MDCK cells.“ Toxins 10 (9). doi: 10.3390/toxins10090353.
- Berthiller, F, Cramer, B, Iha, MH, Krska, R, Lattanzio, V, MacDonald, S, Malone, RJ, Maragos, C, Solfrizzo, M, Stranska-Zachariasova, M, Stroka, J, und Tittlemier, SA. . „Developments in mycotoxin analysis: An update for 2016-2017.“ World Mycotoxin Journal 11 (1): 5–32. doi: 10.3920/WMJ2017.2250.
- Bauer, JI, Gross, M, Cramer, B, Humpf, H, Hamscher, G, und Usleber, E. . „Immunochemical Analysis of Paxilline and Ergot Alkaloid Mycotoxins in Grass Seeds and Plants.“ Journal of Agricultural and Food Chemistry 66 (1): 315–322. doi: 10.1021/acs.jafc.7b05580.
- Faisal, Zelma, Derdák, Diána, Lemli, Beáta, Kunsági-Máté, Sándor, Bálint, Mónika, Hetényi, Csaba, Csepregi, Rita, Koszegi, Tamas, Sueck, Franziska, Cramer, Benedikt, Humpf, Hans-Ulrich, und Poór, Miklós. . „Interaction of 2′R-ochratoxin A with Serum Albumins: Binding Site, Effects of Site Markers, Thermodynamics, Species Differences of Albumin-binding, and Influence of Albumin on Its Toxicity in MDCK Cells.“ Toxins 10 (9): 353. doi: 10.3390/toxins10090353.
- Sueck, F., Poór, M., Faisal, Z., Gertzen, C.G.W., Cramer, B., Lemli, B., Kunsági-Máté, S., Gohlke, H., und Humpf, H.-U. . „Interaction of Ochratoxin A and Its Thermal Degradation Product 2′<i>R</i>-Ochratoxin A with Human Serum Albumin.“ Toxins 10 (7): 256. doi: 10.3390/toxins10070256.
- Viegas, S., Osteresch, B., Almeida, A., Cramer, B., Humpf, H., und Viegas, C. . „Enniatin B and ochratoxin A in the blood serum of workers from the waste management setting.“ Mycotoxin Research 34 (2): 85–90. doi: 10.1007/s12550-017-0302-1.
- Hickert, S., Hermes, L., Marques, L., Focke, C., Cramer, B., Lopes, N., Flett, B., und Humpf, H. . „Alternaria toxins in South African sunflower seeds: cooperative study.“ Mycotoxin Research 33 (4): 309–321. doi: 10.1007/s12550-017-0290-1.
- Cramer, B., Hübner, F., und Humpf, H. . „Applications of High-Performance Liquid Chromatography-Mass Spectrometry Techniques for the Analysis of Chemical Contaminants and Residues in Food.“ In Chemical Contaminants and Residues in Food: Second Edition, Bd. null , herausgegeben von D Schrenk. Elsevier. doi: 10.1016/B978-0-08-100674-0.00003-5.
- Bauer, J., Gross, M., Cramer, B., Wegner, S., Hausmann, H., Hamscher, G., und Usleber, E. . „Detection of the tremorgenic mycotoxin paxilline and its desoxy analog in ergot of rye and barley: a new class of mycotoxins added to an old problem.“ Analytical and Bioanalytical Chemistry 409 (21): 5101–5112. doi: 10.1007/s00216-017-0455-y.
- Schmidt, H., Becker, S., Cramer, B., und Humpf, H. . „Impact of Mechanical and Thermal Energies on the Degradation of T-2 and HT-2 Toxins during Extrusion Cooking of Oat Flour.“ Journal of Agricultural and Food Chemistry 65 (20): 4177–4183. doi: 10.1021/acs.jafc.7b01484.
- Kalinina, S., Jagels, A., Cramer, B., Geisen, R., und Humpf, H. . „Influence of environmental factors on the production of penitrems A–F by Penicillium crustosum.“ Toxins 9 (7). doi: 10.3390/toxins9070210.
- Osteresch, B., Viegas, S., Cramer, B., und Humpf, H. . „Multi-mycotoxin analysis using dried blood spots and dried serum spots.“ Analytical and Bioanalytical Chemistry 409 (13): 3369–3382. doi: 10.1007/s00216-017-0279-9.
- Wu, Q., Kuča, K., Humpf, H., Klímová, B., und Cramer, B. . „Fate of deoxynivalenol and deoxynivalenol-3-glucoside during cereal-based thermal food processing: a review study.“ Mycotoxin Research 33 (1): 79–91. doi: 10.1007/s12550-016-0263-9.
- Muñoz, K., Cramer, B., Dopstadt, J., Humpf, H., und Degen, G. . „Evidence of ochratoxin A conjugates in urine samples from infants and adults.“ Mycotoxin Research 33 (1): 39–47. doi: 10.1007/s12550-016-0261-y.
- Dopstadt, J., Vens-Cappell, S., Neubauer, L., Tudzynski, P., Cramer, B., Dreisewerd, K., und Humpf, H. . „Localization of ergot alkaloids in sclerotia of Claviceps purpurea by matrix-assisted laser desorption/ionization mass spectrometry imaging.“ Analytical and Bioanalytical Chemistry 409 (5): 1221–1230. doi: 10.1007/s00216-016-0047-2.
- Hickert, S., Cramer, B., Letzel, M., und Humpf, H.-U. . „Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry imaging of ochratoxin A and fumonisins in mold-infected food.“ Rapid Communications in Mass Spectrometry 30 (23): 2508–2516. doi: 10.1002/rcm.7733.
- Hövelmann, Y., Hickert, S., Cramer, B., und Humpf, H. . „Determination of exposure to the alternaria mycotoxin tenuazonic acid and its isomer allo-tenuazonic acid in a German population by stable isotope dilution HPLC-MS3.“ Journal of Agricultural and Food Chemistry 64 (34): 6641–6647. doi: 10.1021/acs.jafc.6b02735.
- Osteresch, B., Cramer, B., und Humpf, H. . „Analysis of ochratoxin A in dried blood spots - Correlation between venous and finger-prick blood, the influence of hematocrit and spotted volume.“ Journal of Chromatography B 1020 (null): 158–164. doi: 10.1016/j.jchromb.2016.03.026.
- Hickert, S., Bergmann, M., Ersen, S., Cramer, B., und Humpf, H. . „Survey of Alternaria toxin contamination in food from the German market, using a rapid HPLC-MS/MS approach.“ Mycotoxin Research 32 (1): 7–18. doi: 10.1007/s12550-015-0233-7.
- Bittner, Andrea, Cramer, Benedikt, Harrer, Henning, und Humpf, Hans-Ulrich. . „Structure elucidation and in vitro cytotoxicity of ochratoxin α amide, a new degradation product of ochratoxin A.“ Mycotoxin Research 31 (2): 83–90. doi: 10.1007/s12550-014-0218-y.
- Hickert, S., Krug, I., Cramer, B., und Humpf, H. . „Detection and Quantitative Analysis of the Non-cytotoxic allo-Tenuazonic Acid in Tomato Products by Stable Isotope Dilution HPLC-MS/MS.“ Journal of Agricultural and Food Chemistry 63 (50): 10879–10884. doi: 10.1021/acs.jafc.5b04812.
- Hickert, S., Gerding, J., Ncube, E., Hübner, F., Flett, B., Cramer, B., und Humpf, H. . „A new approach using micro HPLC-MS/MS for multi-mycotoxin analysis in maize samples.“ Mycotoxin Research 31 (2): 109–115. doi: 10.1007/s12550-015-0221-y.
- Gerding, J., Ali, N., Schwartzbord, J., Cramer, B., Brown, D., Degen, G., und Humpf, H. . „A comparative study of the human urinary mycotoxin excretion patterns in Bangladesh, Germany, and Haiti using a rapid and sensitive LC-MS/MS approach.“ Mycotoxin Research 31 (3): 127–136. doi: 10.1007/s12550-015-0223-9.
- Cramer, B., Osteresch, B., Muñoz, K., Hillmann, H., Sibrowski, W., und Humpf, H. . „Biomonitoring using dried blood spots: Detection of ochratoxin A and its degradation product 2'R-ochratoxin A in blood from coffee drinkers*.“ Molecular Nutrition and Food Research 59 (9): 1837–1843. doi: 10.1002/mnfr.201500220.
- Haben, Melina, Cramer, Benedikt, Hickert, Sebastian, Eisenbrand, Gerhard, und Esselen, Melanie. . „Beitrag eines Acrylamid-Niacin-Adduktes zur Reduzierung des Acrylamid-Gehaltes im Lebensmittel.“ In Lebensmittelchmie
- Gerding, Johannes J., Cramer, Benedikt B., und Humpf, Hans Ulrich H.U. . „Determination of mycotoxin exposure in Germany using an LC-MS/MS multibiomarker approach.“ Molecular Nutrition and Food Research 58 (12): 2368. doi: 10.1002/mnfr.201400406.
- Bittner, A, Cramer, B, und Humpf, HU. . „Matrix binding of ochratoxin A during roasting.“ Journal of Agricultural and Food Chemistry 61 (51): 12737–43. doi: 10.1021/jf403984x.
- Silva, Denise Brentan D.B., Guaratini, Thais T., Vessecchi, Ricardo L. R.L., Lopes, Norberto Peporine N.P., Cramer, Benedikt B., Humpf, Hans Ulrich H.U., und Callegari Lopes, JoÃoLuis J.L. . „H2 unimolecular elimination in electrospray ionization mass spectrometry from erythraline, a spirocyclic alkaloid.“ European Journal of Mass Spectrometry 19 (5): 350. doi: 10.1255/ejms.1243.
- Humpf, Hans Ulrich H.U., und Cramer, Benedikt B. . „HPLC-MS/MS-analysis of Mycotoxins: Current applications and future perspectives.“ Journal of Plant Pathology 1 (SUPPL): S1.39..
- Lohrey, Lilia L., Marschik, Stefanie S., Cramer, Benedikt B., und Humpf, Hans Ulrich H.U. . „Large-scale synthesis of isotopically labeled 13C 2-tenuazonic acid and development of a rapid HPLC-MS/MS method for the analysis of tenuazonic acid in tomato and pepper products.“ Journal of Agricultural and Food Chemistry 61 (1): 120. doi: 10.1021/jf305138k.
- von, Bargen C, Hübner, F, Cramer, B, Rzeppa, S, und Humpf, HU. . „Systematic approach for structure elucidation of polyphenolic compounds using a bottom-up approach combining ion trap experiments and accurate mass measurements.“ Journal of Agricultural and Food Chemistry 60 (45): 11274–82. doi: 10.1021/jf3030369.
- Schmidt-Heydt, M., Cramer, B., Graf, I., Lerch, S., Humpf, H., und Geisen, R. . „Wavelength-dependent degradation of ochratoxin and citrinin by light in vitro and in vivo and its implications on Penicillium.“ Toxins 4 (12): 1535–1551. doi: 10.3390/toxins4121535.
- De, Santis Ferreira L., Callejon, D., Engemann, A., Cramer, B., Humpf, H., De, Barros V., Assis, M., Da, Silva D., De, Albuquerque S., Okano, L., Kato, M., und Lopes, N. . „In vitro Metabolism of Grandisin, a Lignan with Anti-chagasic Activity.“ Planta Medica 78 (18): 1939–1941. doi: 10.1055/s-0032-1327876.
- Wu, Q., Engemann, A., Cramer, B., Welsch, T., Yuan, Z., und Humpf, H. . „Intestinal metabolism of T-2 toxin in the pig cecum model.“ Mycotoxin Research 28 (3): 191–198. doi: 10.1007/s12550-012-0134-y.
- Cramer, B., und Humpf, H. . „Applications of HPLC-MS techniques for the analysis of chemical contaminants and residues in food.“ In Chemical Contaminants and Residues in Food, Bd. null , herausgegeben von D Schrenk. Elsevier. doi: 10.1533/9780857095794.1.62.
- Von, Bargen K., Lohrey, L., Cramer, B., und Humpf, H. . „Analysis of the Fusarium mycotoxin moniliformin in cereal samples using 13C 2-moniliformin and high-resolution mass spectrometry.“ Journal of Agricultural and Food Chemistry 60 (14): 3586–3591. doi: 10.1021/jf300323d.
- Vessecchi, R., Julião, Zocolo G., Rubio, Gouvea D., Hübner, F., Cramer, B., Rodrigues, DeMarchi M., Humpf, H., und Lopes, N. . „Re-examination of the anion derivatives of isoflavones by radical fragmentation in negative electrospray ionization tandem mass spectrometry: Experimental and computational studies.“ Rapid Communications in Mass Spectrometry 25 (14): 2020–2026. doi: 10.1002/rcm.5075.
- Wu, Q., Lohrey, L., Cramer, B., Yuan, Z., und Humpf, H. . „Impact of physicochemical parameters on the decomposition of deoxynivalenol during extrusion cooking of wheat grits.“ Journal of Agricultural and Food Chemistry 59 (23): 12480–12485. doi: 10.1021/jf2038604.
- Cramer, B, Harrer, H, Nakamura, K, Uemura, D, und Humpf, HU. . „Total synthesis and cytotoxicity evaluation of all ochratoxin A stereoisomers.“ Bioorganic & Medicinal Chemistry 18 (1): 343–357. doi: 10.1016/j.bmc.2009.10.050.
- Pfeiffer, E, Hildebrand, A, Damm, G, Rapp, A, Cramer, B, Humpf, HU, und Metzler, M. . „Aromatic hydroxylation is a major metabolic pathway of the mycotoxin zearalenone in vitro.“ Molecular Nutrition and Food Research 53 (9): 1123–1133. doi: 10.1002/mnfr.200800584.
- Cramer, B, Konigs, M, und Humpf, HU. . „Identification and in vitro cytotoxicity of ochratoxin a degradation products formed during coffee roasting.“ Journal of Agricultural and Food Chemistry 56 (14): 5673–5681. doi: 10.1021/jf801296z.
- Cramer, B, Bretz, M, und Humpf, HU. . „Stable isotope dilution analysis of the Fusarium mycotoxin zearalenone.“ Journal of Agricultural and Food Chemistry 55 (21): 8353–8358. doi: 10.1021/jf0717283.
- Bretz, M, Beyer, M, Cramer, B, Knecht, A, und Humpf, HU. . „Thermal degradation of the Fusarium mycotoxin deoxynivalenol.“ Journal of Agricultural and Food Chemistry 54 (17): 6445–6451. doi: 10.1021/jf061008g.
- Knecht, A, Cramer, B, und Humpf, HU. . „New Monascus metabolites: Structure elucidation and toxicological properties studied with immortalized human kidney epithelial cells.“ Molecular Nutrition and Food Research 50 (3): 314–321. doi: 10.1002/mnfr.200500229.
- Bretz, M, Beyer, M, Cramer, B, und Humpf, HU. . „Stable isotope dilution analysis of the Fusarium mycotoxins deoxynivalenol and 3-acetyldeoxynivalenol.“ Molecular Nutrition and Food Research 50 (3): 251–260. doi: 10.1002/mnfr.200500230.
- Bretz, M, Beyer, M, Cramer, B, und Humpf, HU. . „Synthesis of stable isotope labeled 3-acetyldeoxynivalenol.“ Molecular Nutrition and Food Research 49 (12): 1151–1153. doi: 10.1002/mnfr.200500153.