Research Foci
Mycotoxins
Identification and quantification of mycotoxins in food and the environment. Impact of food processing on mycotoxins.
Process-induced contaminants
Formation and minimization of process contaminants such as furans, monochloropropanediols (MCPDs), glycidols and acrylamide
Human biomonitoring
Human biomonitoring of mycotoxins and process contaminants, exposure assessment.
Instrumental analysis (HPLC-MS/MS, HPLC-HRMS, GC-MS)
Development of new analytical methods applying mass spectrometry.
CV
Academic Education
- Kollegiat der International Research Training Group Münster/D - Nagoya/J (IRTG-MS/NG)
- Dissertation (Prof. Dr. H.-U. Humpf), Lehrstuhl für Lebensmittelchemie der WWU Münster
- Forschungsaufenthalt an der Nagoya University, Nagoya, Japan, Department of Chemistry (Prof. Dr. D. Uemura)
Positions
- Senior Scientist at the Institute of Food Chemistry of the University of Muenster, head of the service unit "Instrumental analysis"
- Post-Doc am Institut für Lebensmittelchemie der WWU Münster (Prof. Dr. H.-U. Humpf)
Honors
- Stockmeyer Wissenschaftspreis – Heinrich-Stockmeyer-Stiftung
External Functions
- German Institute of Standards (DIN) (NA 057-01-14 AA "Process contaminants", Mitglied)
- Society for Mycotoxin Research e.V. (Treasurer)
- Member of the editorial board of the journal "Mycotoxin Research"
- Mitglied der §64-LFGB Arbeitssgruppe "Mykotoxine" beim Bundesamt für Verbraucherschutz und Lebensmittelsicherheit
Teaching
- Seminar: Instrumentelle Analytik [124225]
- [ – | Mon, – | | LC 3]
- [ – | Fri, – | | LC 3]
- Seminar: Institutsseminar [124233]
(in cooperation with Florian Hübner, Hans-Ulrich Humpf, Melanie Esselen and Matthias Behrens)- [Thu, – | ]
- Seminar: Aktuelle Forschung [124229]
(in cooperation with Florian Hübner, Hans-Ulrich Humpf, Melanie Esselen and Matthias Behrens)- [ – | Thu, – | | LC 1]
- Practical: Instrumentelles Messtechnikpraktikum [124226]
- Presentation: Vortrag zur Bachelorarbeit [124219]
(in cooperation with Michael Lange-Aperdannier, Hans-Ulrich Humpf, Florian Hübner, Melanie Esselen and Matthias Behrens)- [ – | Single Course]
- Seminar: Aktuelle Forschung
(in cooperation with Florian Hübner, Hans-Ulrich Humpf, Melanie Esselen and Matthias Behrens)- Seminar: Instrumentelle Lebensmittel- und Futtermittelanalytik
- Seminar: Institutsseminar
(in cooperation with Florian Hübner, Hans-Ulrich Humpf, Melanie Esselen and Matthias Behrens)- Practical: Instrumentelle Lebensmittel- und Futtermittelanalytik
(in cooperation with Florian Hübner)
Publications
- Lipinski, S, Becker, M, Lindekamp, N, Humpf, H, and Cramer, B. . “Formation of Furan, Alkylfurans and Acrylamide during Breakfast Cereal Manufacturing: Comparison of Model Experiments with Industrial Processes.” Preprint. Food Control 179: 111598.. doi: 10.1016/j.foodcont.2025.111598.
- Cramer, B, Bahlmann, A, DeRosa, M, Kodikara, C, Malone, R, Steiner, D, Suman, M, Sumarah, M, and Tittlemier, S. . “Developments in mycotoxin analysis: an update for 2024-2025.” World Mycotoxin Journal 19 (1): 3–35. doi: 10.1163/18750796-bja10035.
- Phillips, E., Ngure, F.M., Kassim, N., Turner, P.C., Makule, E., Smith, L.E., Makori, N., Cramer, B., Humpf, H.-U., Nelson, R.J., and Stoltzfus, R.J. . “The effect of an intervention to reduce aflatoxin consumption from 6 to 18 mo of age on length-for-age z-scores in rural Tanzania: a cluster-randomized trial.” American Journal of Clinical Nutrition 121 (2): 333–342. doi: 10.1016/j.ajcnut.2024.11.022.
- Lipinski, Sarah, Becker, Marlen, Meyer, Jens Chr., Nowakowski, Christine, Humpf, Hans-Ulrich, and Cramer, Benedikt. . “Impact of Physicochemical Parameters on the Furan, Alkylfuran, and Acrylamide Formation during Extrusion Cooking of Breakfast Cereals.” ACS Food Science & Technology 2025. doi: 10.1021/acsfoodscitech.4c00727.
- Kelman, M.J., Renaud, J.B., McCarron, P., Hoogstra, S., Chow, W., Wang, J., Varga, E., Patriarca, A., Medina Vaya, A., Visintin, L., Nguyen, T., De Boevre, M., De Saeger, S., Karanghat, V., Vuckovic, D., McMullin, D.R.Dall' Asta C. Ayeni K., Warth, B., Huang, M., Tittlemier, S., Mats, L., Cao, R., Sulyok, M., Xu, K., Berthiller, F., Kuhn, M., Cramer, B., Ciasca, B., Lattanzio, V., De Baere, S., Croubels, S., DesRochers, N., Sura, S., Bates, J., Wright, E.J., Thapa, I., Blackwell, B.A., Zhang, K., Wong, J., Burns, L., Borts, D.J., and Sumarah, M.W. . “International interlaboratory study to normalize liquid chromatography-based mycotoxin retention times through implementation of a retention index system.” Journal of Chromatography A 1745: 465732.. doi: 10.1016/j.chroma.2025.465732.
- Zinßius, L, Keuter, L, Krischek, C, Jessberger, N, Cramer, B, and Plötz, M. . “Influence of the β-Casein Genotype of Cow’s Milk (A1, A2) on the Quality and $β$-Casomorphin-7 (BCM-7) Content of a Semi-Hard Cheese During Production.” Foods 14 (3): 463–463. doi: 10.3390/foods14030463.
- Brückner, L, Neuendorff, F, Hadenfeldt, K, Behrens, M, Cramer, B, and Humpf, H. . “Thermal Stability and Matrix Binding of Citrinin in the Thermal Processing of Starch-Rich Foods.” Toxins 17 (2): 86–86. doi: 10.3390/toxins17020086.
- Tittlemier, S, Cramer, B, DeRosa, M, Dzuman, Z, Kodikara, C, Malone, R, Maragos, C, Suman, M, and Sumarah, M. . “Developments in analytical techniques for mycotoxin determination: an update for 2023-24.” World Mycotoxin Journal 18 (1): 3–30. doi: 10.1163/18750796-BJA10013.
- Cramer, Benedikt, Visintin, Lia, Elias, Maris, Michael, Kuhn, H., Degen Gisela, Turner, Paul C., Humpf, Hans-Ulrich, and De Saeger, Sarah. . “Human biomonitoring of mycotoxins: key challenges and future directions.” Mycotoxin Research 42 (1) 13. doi: 10.1007/s12550-025-00612-2.
- Moretti, Antonio, Loi, Martina, Lippolis, Vincenzo, De Girolamo, Annalisa, Fanelli, Francesca, and Cramer, Benedikt. . “From climate change to analytical advances on mycotoxin research: key insights from the 46th Mycotoxin Workshop.” Mycotoxin Research 42 (1). doi: 10.1007/s12550-025-00629-7.
- Kuhn, Michael, Kyei, Nicholas N.A., Cramer, Benedikt, and Humpf, Hans-Ulrich. . “Online solid phase extraction-LC-MS/MS with two step peak focusing for sensitive multi-analyte analysis of mycotoxins in urine.” Microchemical Journal 219 115821. doi: 10.1016/j.microc.2025.115821.
- Witzel, K, Djalali, Farahani-Kofoet R, Döll, S, Lindemann, V, Cramer, B, Humpf, H, and Zrenner, R. . “Metabolomics and dual proteomics identify contrasting patterns of major pathways affected in asparagus shoot upon Fusarium infection.” Plant and Soil 2024. doi: 10.1007/s11104-024-07069-9.
- Modrzewska, M., Popowski, D., Błaszczyk, L., Stępień, Ł., Urbaniak, M., Bryła, M., Cramer, B., Humpf, H.-U., and Twarużek, M. . “Antagonistic properties against Fusarium sporotrichioides and glycosylation of HT-2 and T-2 toxins by selected Trichoderma strains.” Scientific Reports 14 (1). doi: 10.1038/s41598-024-55920-x.
- Hassan, R., Gerdemann, A., Cramer, B., Hobloss, Z., Myllys, M., González, D., Albrecht, W., Veerkamp, J., Friebel, A., Hoehme, S., Esselen, M., Degen, G., Humpf, H., Hengstler, J., and Ghallab, A. . “Integrated data from intravital imaging and HPLC–MS/MS analysis reveal large interspecies differences in AFB1 metabolism in mice and rats.” Archives of Toxicology 98 (4): 1081–1093. doi: 10.1007/s00204-024-03688-4.
- Pierzgalski, A., Bryła, M., B., Cramerm, Humpf, H.-U., and Twarużek, M. . “Co-occurrence of T-2 and HT-2 Mycotoxins and α and β Anomers of Their Glucosides in Wheat and Oat Grains.” Journal of Agricultural and Food Chemistry 72 (6): 3150–3159. doi: 10.1021/acs.jafc.3c07465.
- Pierzgalski, Adam, Bryla, Marcin, Cramer, Benedikt, Humpf, Hans-Ulrich, and Twaruzek, Magdalena. . “Co-occurrence of T-2 and HT-2 Mycotoxins and α and <i>β</i> Anomers of Their Glucosides in Wheat and Oat Grains.” Journal of Agricultural and Food Chemistry 72 (6). doi: 10.1021/acs.jafc.3c07465.
- Hassan, Reham, Gerdemann, Andrea, Cramer, Benedikt, Hobloss, Zaynab, Myllys, Maiju, Gonzalez, Daniela, Albrecht, Wiebke, Veerkamp, Jannik, Friebel, Adrian, Hoehme, Stefan, Esselen, Melanie, Degen, Gisela H., Humpf, Hans-Ulrich, Hengstler, Jan G., and Ghallab, Ahmed. . “Integrated data from intravital imaging and HPLC-MS/MS analysis reveal large interspecies differences in AFB1 metabolism in mice and rats.” Archives of Toxicology 1. doi: 10.1007/s00204-024-03688-4.
- Kuhn, Michael, Hassan, Reham, Gonzalez, Daniela, Myllys, Maiju, Hobloss, Zaynab, Degen, Gisela H., Humpf, Hans-Ulrich, Hengstler, Jan G., Cramer, Benedikt, and Ghallab, Ahmed. . “Role of albumin in the metabolism and excretion of ochratoxin A.” Mycotoxin Research 1. doi: 10.1007/s12550-024-00538-1.
- Brückner, Lea, Cramer, Benedikt, and Humpf, Hans-Ulrich. . “Reactions of citrinin with amino compounds modelling thermal food processing.” Mycotoxin Research 40 (4): 709–720. doi: 10.1007/s12550-024-00557-y.
- Varga, Elisabeth, Marko, Doris, Meyer, Karsten, Cramer, Benedikt, Humpf, Hans-Ulrich, and Plötz, Madeleine. . “Vienna, the ‘City of Music’, meets mycotoxin research at the 45th Mycotoxin Workshop.” Mycotoxin Research 40 (3): 327–329. doi: 10.1007/s12550-024-00542-5.
- Tittlemier, S., Cramer, B., De Rosa, M., Dzuman, Z., Malone, R., Maragos, C., Suman, M., and Sumarah, M. . “Developments in analytical techniques for mycotoxin determination: an update for 2022-23.” World Mycotoxin Journal 17 (1): 3–26. doi: 10.1163/18750796-bja10002.
- Gerdemann, A, Cramer, B, Degen, GH, Veerkamp, J, Günther, G, Albrecht, W, Behrens, M, Esselen, M, Ghallab, A, Hengstler, JG, and Humpf, H-U. . “Comparative metabolism of aflatoxin B1 in mouse, rat and human primary hepatocytes using HPLC–MS/MS.” Archives of Toxicology 97 (12): 3179–3196. doi: 10.1007/s00204-023-03607-z.
- Nikmaram, N., Brückner, L., Cramer, B., Humpf, H.-U., and Keener, K. . “Degradation products of aflatoxin M1 (AFM1) formed by high voltage atmospheric cold plasma (HVACP) treatment.” Toxicon 230. doi: 10.1016/j.toxicon.2023.107160.
- Lipinski, S., Lindekamp, N., Funck, N., Cramer, B., and Humpf, H.-U. . “Determination of furan and alkylfuran in breakfast cereals from the European market and their correlation with acrylamide levels.” European Food Research and Technology 2023. doi: 10.1007/s00217-023-04374-y.
- Tittlemier, S.A., Cramer, B., DeRosa, M.C., Lattanzio, V.M.T., Malone, R., Maragos, C., Stranska, M., and Sumarah, M.W. . “Developments in mycotoxin analysis: an update for 2021-22.” World Mycotoxin Journal 16 (1): 3–24. doi: 10.3920/WMJ2022.2822.
- Kyei, N.N.A., Waid, J.L., Ali, N., Cramer, B., Humpf, H.-U., and Gabrysch, S. . “Maternal exposure to multiple mycotoxins and adverse pregnancy outcomes: a prospective cohort study in rural Bangladesh.” Archives of Toxicology 97 (6): 1795–1812. doi: 10.1007/s00204-023-03491-7.
- Kyei, N.N.A., Cramer, B.Humpf H.-U., Degen, G.H., Ali, N., and Gabrysch, S. . “Assessment of multiple mycotoxin exposure and its association with food consumption: a human biomonitoring study in a pregnant cohort in rural Bangladesh.” Archives of Toxicology 96 (7): 2123–2138. doi: 10.1007/s00204-022-03288-0.
- Lindemann, V, Schleiner, T, Maier, U, Fels, H, Cramer, B, and Humpf, HU. . “Analysis of mold and mycotoxins in naturally infested indoor building materials.” Mycotoxin Research 2022. doi: 10.1007/s12550-022-00461-3.
- Puel, O, Cramer, B., Oswald, I.P., and Humpf, H.-U. . “From the laboratory bench to the lecture hall: latest findings from mycotoxin research presented at the 43rd Mycotoxin Workshop.” Mycotoxin Research 2022. doi: 10.1007/s12550-022-00462-2.
- Tittlemier, S.A., Cramer, B., Dall'Asta, C., DeRosa, M.C., Lattanzio, V.M.T., Malone, R., Maragos, C., Stranska, M., and Sumarah, M.W. . “Developments in mycotoxin analysis: an update for 2020-2021.” World Mycotoxin Journal 15 (1): 3–25. doi: 10.3920/WMJ2021.2752.
- Penczynski, K, Cramer, B, Dietrich, S, Humpf, H, Abraham, K, and Weikert, C. . “Mycotoxins in Serum and 24-h Urine of Vegans and Omnivores from the Risks and Benefits of a Vegan Diet (RBVD) Study.” Molecular Nutrition and Food Research 66 (6). doi: 10.1002/mnfr.202100874.
- Lindemann, V, Schmidt, J, Cramer, B, and Humpf, H. . “Detection of Mycotoxins in Highly Matrix-Loaded House-Dust Samples by QTOF-HRMS, IM-QTOF-HRMS, and TQMS: Advantages and Disadvantages.” Analytical Chemistry 94 (10): 4209–4217. doi: 10.1021/acs.analchem.1c04254.
- Rehagel, C, Akineden, Ö, Geisen, R, Cramer, B, Plötz, M, and Usleber, E. . “Development and application of a competitive enzyme immunoassay for the detection of penitrem A in fungal mycelium: Evidence for frequent occurrence of multiple indole-containing mycotoxins in mouldy foods.” Food Control 132: 108558. doi: 10.1016/j.foodcont.2021.108558.
- R., Hassan, A., Friebel, L., Brackhagen, Z., Hobloss, M., Myllys, D., González, W., Albrecht, E.S.I., Mohammed, A.l., Seddek, R., Marchan, C., Cadenas, B., Cramer, H.U., Humpf, L., Hartl, B., Simbrunner, T., Reiberger, M., Trauner, S., Hoehme, G.H., Degen, J.G., Hengstler, and A., Ghallab. . “Hypoalbuminemia affects the spatio-temporal tissue distribution of ochratoxin A in liver and kidneys: consequences for organ toxicity.” Archives of Toxicology 96 (11): 2967–2981. doi: 10.1007/s00204-022-03361-8.
- R., Hassan, D., González, Z., Hobloss, L., Brackhagen, M., Myllys, A., Friebel, A.l., Seddek, R., Marchan, B., Cramer, H.U., Humpf, S., Hoehme, G.H., Degen, J.G., Hengstler, and A., Ghallab. . “Inhibition of cytochrome P450 enhances the nephro- and hepatotoxicity of ochratoxin A.” Archives of Toxicology 96 (12): 3349–3361. doi: 10.1007/s00204-022-03395-y.
- Hermes, L, Römermann, J, Cramer, B, and Esselen, M. . “Quantitative Analysis of β-Asarone Derivatives in <i>Acorus calamus</i> and Herbal Food Products by HPLC-MS/MS.” Journal of Agricultural and Food Chemistry 69 (2): 776–782. doi: 10.1021/acs.jafc.0c05513.
- Hermes, L, Römermann, J, Cramer, B, and Esselen, M. . “Quantitative Analysis of β-Asarone Derivatives in Acorus calamus and Herbal Food Products by HPLC-MS/MS.” Journal of Agricultural and Food Chemistry Online ahead of print. doi: 10.1021/acs.jafc.0c05513.
- Kalinina, S, Cramer, B, and Humpf, H. . “Current and future perspectives of mycotoxin research — report from the 42nd Mycotoxin Workshop (Online conference).” Mycotoxin Research 37 (4): 275–278. doi: 10.1007/s12550-021-00439-7.
- Hermes, Lena, Römermann, Jannis, Cramer, Benedikt, and Esselen, Melanie. . “Phase II metabolism of asarone isomers in vitro and in humans using HPLC-MS/MS and HPLC-QToF/MS.” Foods 10 (9): 2032.. doi: 10.3390/foods10092032.
- Schmidt, J, Cramer, B, Turner, PC, Stoltzfus, RJ, Humphrey, JH, Smith, LE, and Humpf, H-. . “Determination of urinary mycotoxin biomarkers using a sensitive online solid phase extraction‐uhplc‐ms/ms method.” Toxins 13 (6). doi: 10.3390/toxins13060418.
- Schmidt, J, Lindemann, V, Olsen, M, Cramer, B, and Humpf, H-U. . “Dried urine spots as sampling technique for multi-mycotoxin analysis in human urine.” Mycotoxin Research 37 (2): 129–140. doi: 10.1007/s12550-021-00423-1.
- Ghallab, A, Hassan, R, Myllys, M, Albrecht, W, Friebel, A, Hoehme, S, Hofmann, U, Seddek, A-, Braeuning, A, Kuepfer, L, Cramer, B, Humpf, H-, Boor, P, Degen, GH, and Hengstler, JG. . “Subcellular spatio-temporal intravital kinetics of aflatoxin B1 and ochratoxin A in liver and kidney.” Archives of Toxicology 95 (6): 2163–2177. doi: 10.1007/s00204-021-03073-5.
- Tittlemier, S., Brunkhorst, J., Cramer, B., DeRosa, M., Lattanzio, V., Malone, R., Maragos, C., Stranska, M., and Sumarah, M. . “Developments in mycotoxin analysis: An update for 2019-2020.” World Mycotoxin Journal 14 (1): 3 – 26–3 – 26. doi: 10.3920/WMJ2020.2664.
- Jagels, A, Stephan, F, Ernst, S, Lindemann, V, Cramer, B, Hübner, F, and Humpf, H-U. . “Artificial vs natural Stachybotrys infestation—Comparison of mycotoxin production on various building materials.” Indoor Air 30 (6): 1268–1282. doi: 10.1111/ina.12705.
- Tittlemier, SA, Cramer, B, Dall'Asta, C, Iha, MH, Lattanzio, VMT, Maragos, C, Solfrizzo, M, Stranska, M, Stroka, J, and Sumarah, M. . “Developments in mycotoxin analysis: An update for 2018-19.” World Mycotoxin Journal 13 (1): 3–24. doi: 10.3920/WMJ2019.2535.
- Warensjö, Lemming E, Montano, Montes A, Schmidt, J, Cramer, B, Humpf, H-, Moraeus, L, and Olsen, M. . “Mycotoxins in blood and urine of Swedish adolescents—possible associations to food intake and other background characteristics.” Mycotoxin Research 36 (2): 193–206. doi: 10.1007/s12550-019-00381-9.
- Sueck, F, Hemp, V, Specht, J, Torres, O, Cramer, B, and Humpf, H-U. . “Occurrence of the ochratoxin A degradation product 2′R-ochratoxin a in coffee and other food: An update.” Toxins 11 (6): 329.. doi: 10.3390/toxins11060329.
- Kuchenbuch, HS, Cramer, B, and Humpf, H-U. . “Matrix binding of T-2 toxin: structure elucidation of reaction products and indications on the fate of a relevant food-borne toxin during heating.” Mycotoxin Research 35 (3): 261–270. doi: 10.1007/s12550-019-00350-2.
- Sueck, F, Cramer, B, Czeschinski, P, and Humpf, H-. . “Human Study on the Kinetics of 2′R-Ochratoxin A in the Blood of Coffee Drinkers.” Molecular Nutrition and Food Research 63 (4): 1801026.. doi: 10.1002/mnfr.201801026.
- Kuchenbuch, HS, Schulz, M, Becker, S, Cramer, B, and Humpf, H-. . ACS Symposium Series, Vol. 1306, Thermal reactions and the formation of degradation products of T-2 and HT-2 toxin during processing of oats American Chemical Society. doi: 10.1021/bk-2019-1306.ch007.
- Sueck, F, Specht, J, Cramer, B, and Humpf, H-. . “Identification of ochratoxin-N-acetyl-L-cysteine as a new ochratoxin A metabolite and potential biomarker in human urine.” Mycotoxin Research 2020 (36): 1–10. doi: 10.1007/s12550-019-00360-0.
- Jagels, A, Lindemann, V, Ulrich, S, Gottschalk, C, Cramer, B, Hübner, F, Gareis, M, and Humpf, H-U. . “Exploring secondary metabolite profiles of stachybotrys spp. By LC-MS/MS.” Toxins 11 (3): 133.. doi: 10.3390/toxins11030133.
- Tittlemier, SA, Cramer, B, Dall'Asta, C, Iha, MH, Lattanzio, VMT, Malone, RJ, Maragos, C, Solfrizzo, M, Stranska-Zachariasova, M, and Stroka, J. . “Developments in mycotoxin analysis: An update for 2017-2018.” World Mycotoxin Journal 12 (1): 3–29. doi: 10.3920/WMJ2018.2398.
- Kuchenbuch, Henning S., Becker, Stefanie, Schulz, Mareike, Cramer, Benedikt, and Humpf, Hans-Ulrich. . “Thermal stability of T-2 and HT-2 toxins during biscuit- and crunchy muesli-making and roasting.” Food Additives and Contaminants: Part A: Chemistry, Analysis, Control, Exposure and Risk Assessment 35: 2158–2167. doi: 10.1080/19440049.2018.1530456.
- Andreeßen, C., Wolf, N., Cramer, B., Humpf, H., and Steinbüchel, A. . “In vitro biosynthesis of 3-mercaptolactate by lactate dehydrogenases.” Enzyme and Microbial Technology 108 (null): 1–10. doi: 10.1016/j.enzmictec.2017.08.005.
- Kalinina, SA, Kalinin, DV, Hövelmann, Y, Daniliuc, CG, Mück-Lichtenfeld, C, Cramer, B, and Humpf, H. . “Auranthine, a Benzodiazepinone from Penicillium aurantiogriseum: Refined Structure, Absolute Configuration, and Cytotoxicity.” Journal of Natural Products 81 (10): 2177–2186. doi: 10.1021/acs.jnatprod.8b00187.
- Sueck, F, Poór, M, Faisal, Z, Gertzen, C, Cramer, B, Lemli, B, Kunsági-Máté, S, Gohlke, H, and Humpf, H-U. . “Interaction of ochratoxin A and its thermal degradation product 2'R-ochratoxin A with human serum albumin.” Toxins 10 (7). doi: 10.3390/toxins10070256.
- Schmidt, HS, Schulz, M, Focke, C, Becker, S, Cramer, B, and Humpf, H-U. . “Glucosylation of T-2 and HT-2 toxins using biotransformation and chemical synthesis: Preparation, stereochemistry, and stability.” Mycotoxin Research 34 (3): 159–172. doi: 10.1007/s12550-018-0310-9.
- Kalinina, SA, Jagels, A, Hickert, S, Mauriz, Marques LM, Cramer, B, and Humpf, H. . “Detection of the Cytotoxic Penitrems A-F in Cheese from the European Single Market by HPLC-MS/MS.” Journal of Agricultural and Food Chemistry 66 (5): 1264–1269. doi: 10.1021/acs.jafc.7b06001.
- Faisal, Z, Derdák, D, Lemli, B, Kunsági-Máté, S, Bálint, M, Hetényi, C, Csepregi, R, Kőszegi, T, Sueck, F, Cramer, B, Humpf, H, and Poór, M. . “Interaction of 2'R-ochratoxin A with serum albumins: Binding site, effects of site markers, thermodynamics, species differences of albumin-binding, and influence of albumin on its toxicity in MDCK cells.” Toxins 10 (9). doi: 10.3390/toxins10090353.
- Berthiller, F, Cramer, B, Iha, MH, Krska, R, Lattanzio, V, MacDonald, S, Malone, RJ, Maragos, C, Solfrizzo, M, Stranska-Zachariasova, M, Stroka, J, and Tittlemier, SA. . “Developments in mycotoxin analysis: An update for 2016-2017.” World Mycotoxin Journal 11 (1): 5–32. doi: 10.3920/WMJ2017.2250.
- Bauer, JI, Gross, M, Cramer, B, Humpf, H, Hamscher, G, and Usleber, E. . “Immunochemical Analysis of Paxilline and Ergot Alkaloid Mycotoxins in Grass Seeds and Plants.” Journal of Agricultural and Food Chemistry 66 (1): 315–322. doi: 10.1021/acs.jafc.7b05580.
- Faisal, Zelma, Derdák, Diána, Lemli, Beáta, Kunsági-Máté, Sándor, Bálint, Mónika, Hetényi, Csaba, Csepregi, Rita, Koszegi, Tamas, Sueck, Franziska, Cramer, Benedikt, Humpf, Hans-Ulrich, and Poór, Miklós. . “Interaction of 2′R-ochratoxin A with Serum Albumins: Binding Site, Effects of Site Markers, Thermodynamics, Species Differences of Albumin-binding, and Influence of Albumin on Its Toxicity in MDCK Cells.” Toxins 10 (9): 353. doi: 10.3390/toxins10090353.
- Sueck, F., Poór, M., Faisal, Z., Gertzen, C.G.W., Cramer, B., Lemli, B., Kunsági-Máté, S., Gohlke, H., and Humpf, H.-U. . “Interaction of Ochratoxin A and Its Thermal Degradation Product 2′<i>R</i>-Ochratoxin A with Human Serum Albumin.” Toxins 10 (7): 256. doi: 10.3390/toxins10070256.
- Viegas, S., Osteresch, B., Almeida, A., Cramer, B., Humpf, H., and Viegas, C. . “Enniatin B and ochratoxin A in the blood serum of workers from the waste management setting.” Mycotoxin Research 34 (2): 85–90. doi: 10.1007/s12550-017-0302-1.
- Hickert, S., Hermes, L., Marques, L., Focke, C., Cramer, B., Lopes, N., Flett, B., and Humpf, H. . “Alternaria toxins in South African sunflower seeds: cooperative study.” Mycotoxin Research 33 (4): 309–321. doi: 10.1007/s12550-017-0290-1.
- Cramer, B., Hübner, F., and Humpf, H. . “Applications of High-Performance Liquid Chromatography-Mass Spectrometry Techniques for the Analysis of Chemical Contaminants and Residues in Food.” in Chemical Contaminants and Residues in Food: Second Edition, Vol. null , edited by D Schrenk. Elsevier. doi: 10.1016/B978-0-08-100674-0.00003-5.
- Bauer, J., Gross, M., Cramer, B., Wegner, S., Hausmann, H., Hamscher, G., and Usleber, E. . “Detection of the tremorgenic mycotoxin paxilline and its desoxy analog in ergot of rye and barley: a new class of mycotoxins added to an old problem.” Analytical and Bioanalytical Chemistry 409 (21): 5101–5112. doi: 10.1007/s00216-017-0455-y.
- Schmidt, H., Becker, S., Cramer, B., and Humpf, H. . “Impact of Mechanical and Thermal Energies on the Degradation of T-2 and HT-2 Toxins during Extrusion Cooking of Oat Flour.” Journal of Agricultural and Food Chemistry 65 (20): 4177–4183. doi: 10.1021/acs.jafc.7b01484.
- Kalinina, S., Jagels, A., Cramer, B., Geisen, R., and Humpf, H. . “Influence of environmental factors on the production of penitrems A–F by Penicillium crustosum.” Toxins 9 (7). doi: 10.3390/toxins9070210.
- Osteresch, B., Viegas, S., Cramer, B., and Humpf, H. . “Multi-mycotoxin analysis using dried blood spots and dried serum spots.” Analytical and Bioanalytical Chemistry 409 (13): 3369–3382. doi: 10.1007/s00216-017-0279-9.
- Wu, Q., Kuča, K., Humpf, H., Klímová, B., and Cramer, B. . “Fate of deoxynivalenol and deoxynivalenol-3-glucoside during cereal-based thermal food processing: a review study.” Mycotoxin Research 33 (1): 79–91. doi: 10.1007/s12550-016-0263-9.
- Muñoz, K., Cramer, B., Dopstadt, J., Humpf, H., and Degen, G. . “Evidence of ochratoxin A conjugates in urine samples from infants and adults.” Mycotoxin Research 33 (1): 39–47. doi: 10.1007/s12550-016-0261-y.
- Dopstadt, J., Vens-Cappell, S., Neubauer, L., Tudzynski, P., Cramer, B., Dreisewerd, K., and Humpf, H. . “Localization of ergot alkaloids in sclerotia of Claviceps purpurea by matrix-assisted laser desorption/ionization mass spectrometry imaging.” Analytical and Bioanalytical Chemistry 409 (5): 1221–1230. doi: 10.1007/s00216-016-0047-2.
- Hickert, S., Cramer, B., Letzel, M., and Humpf, H.-U. . “Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry imaging of ochratoxin A and fumonisins in mold-infected food.” Rapid Communications in Mass Spectrometry 30 (23): 2508–2516. doi: 10.1002/rcm.7733.
- Hövelmann, Y., Hickert, S., Cramer, B., and Humpf, H. . “Determination of exposure to the alternaria mycotoxin tenuazonic acid and its isomer allo-tenuazonic acid in a German population by stable isotope dilution HPLC-MS3.” Journal of Agricultural and Food Chemistry 64 (34): 6641–6647. doi: 10.1021/acs.jafc.6b02735.
- Osteresch, B., Cramer, B., and Humpf, H. . “Analysis of ochratoxin A in dried blood spots - Correlation between venous and finger-prick blood, the influence of hematocrit and spotted volume.” Journal of Chromatography B 1020 (null): 158–164. doi: 10.1016/j.jchromb.2016.03.026.
- Hickert, S., Bergmann, M., Ersen, S., Cramer, B., and Humpf, H. . “Survey of Alternaria toxin contamination in food from the German market, using a rapid HPLC-MS/MS approach.” Mycotoxin Research 32 (1): 7–18. doi: 10.1007/s12550-015-0233-7.
- Bittner, Andrea, Cramer, Benedikt, Harrer, Henning, and Humpf, Hans-Ulrich. . “Structure elucidation and in vitro cytotoxicity of ochratoxin α amide, a new degradation product of ochratoxin A.” Mycotoxin Research 31 (2): 83–90. doi: 10.1007/s12550-014-0218-y.
- Hickert, S., Krug, I., Cramer, B., and Humpf, H. . “Detection and Quantitative Analysis of the Non-cytotoxic allo-Tenuazonic Acid in Tomato Products by Stable Isotope Dilution HPLC-MS/MS.” Journal of Agricultural and Food Chemistry 63 (50): 10879–10884. doi: 10.1021/acs.jafc.5b04812.
- Hickert, S., Gerding, J., Ncube, E., Hübner, F., Flett, B., Cramer, B., and Humpf, H. . “A new approach using micro HPLC-MS/MS for multi-mycotoxin analysis in maize samples.” Mycotoxin Research 31 (2): 109–115. doi: 10.1007/s12550-015-0221-y.
- Gerding, J., Ali, N., Schwartzbord, J., Cramer, B., Brown, D., Degen, G., and Humpf, H. . “A comparative study of the human urinary mycotoxin excretion patterns in Bangladesh, Germany, and Haiti using a rapid and sensitive LC-MS/MS approach.” Mycotoxin Research 31 (3): 127–136. doi: 10.1007/s12550-015-0223-9.
- Cramer, B., Osteresch, B., Muñoz, K., Hillmann, H., Sibrowski, W., and Humpf, H. . “Biomonitoring using dried blood spots: Detection of ochratoxin A and its degradation product 2'R-ochratoxin A in blood from coffee drinkers*.” Molecular Nutrition and Food Research 59 (9): 1837–1843. doi: 10.1002/mnfr.201500220.
- Haben, Melina, Cramer, Benedikt, Hickert, Sebastian, Eisenbrand, Gerhard, and Esselen, Melanie. . “Beitrag eines Acrylamid-Niacin-Adduktes zur Reduzierung des Acrylamid-Gehaltes im Lebensmittel.” in Lebensmittelchmie
- Gerding, Johannes J., Cramer, Benedikt B., and Humpf, Hans Ulrich H.U. . “Determination of mycotoxin exposure in Germany using an LC-MS/MS multibiomarker approach.” Molecular Nutrition and Food Research 58 (12): 2368. doi: 10.1002/mnfr.201400406.
- Bittner, A, Cramer, B, and Humpf, HU. . “Matrix binding of ochratoxin A during roasting.” Journal of Agricultural and Food Chemistry 61 (51): 12737–43. doi: 10.1021/jf403984x.
- Silva, Denise Brentan D.B., Guaratini, Thais T., Vessecchi, Ricardo L. R.L., Lopes, Norberto Peporine N.P., Cramer, Benedikt B., Humpf, Hans Ulrich H.U., and Callegari Lopes, JoÃoLuis J.L. . “H2 unimolecular elimination in electrospray ionization mass spectrometry from erythraline, a spirocyclic alkaloid.” European Journal of Mass Spectrometry 19 (5): 350. doi: 10.1255/ejms.1243.
- Humpf, Hans Ulrich H.U., and Cramer, Benedikt B. . “HPLC-MS/MS-analysis of Mycotoxins: Current applications and future perspectives.” Journal of Plant Pathology 1 (SUPPL): S1.39..
- Lohrey, Lilia L., Marschik, Stefanie S., Cramer, Benedikt B., and Humpf, Hans Ulrich H.U. . “Large-scale synthesis of isotopically labeled 13C 2-tenuazonic acid and development of a rapid HPLC-MS/MS method for the analysis of tenuazonic acid in tomato and pepper products.” Journal of Agricultural and Food Chemistry 61 (1): 120. doi: 10.1021/jf305138k.
- von, Bargen C, Hübner, F, Cramer, B, Rzeppa, S, and Humpf, HU. . “Systematic approach for structure elucidation of polyphenolic compounds using a bottom-up approach combining ion trap experiments and accurate mass measurements.” Journal of Agricultural and Food Chemistry 60 (45): 11274–82. doi: 10.1021/jf3030369.
- Schmidt-Heydt, M., Cramer, B., Graf, I., Lerch, S., Humpf, H., and Geisen, R. . “Wavelength-dependent degradation of ochratoxin and citrinin by light in vitro and in vivo and its implications on Penicillium.” Toxins 4 (12): 1535–1551. doi: 10.3390/toxins4121535.
- De, Santis Ferreira L., Callejon, D., Engemann, A., Cramer, B., Humpf, H., De, Barros V., Assis, M., Da, Silva D., De, Albuquerque S., Okano, L., Kato, M., and Lopes, N. . “In vitro Metabolism of Grandisin, a Lignan with Anti-chagasic Activity.” Planta Medica 78 (18): 1939–1941. doi: 10.1055/s-0032-1327876.
- Wu, Q., Engemann, A., Cramer, B., Welsch, T., Yuan, Z., and Humpf, H. . “Intestinal metabolism of T-2 toxin in the pig cecum model.” Mycotoxin Research 28 (3): 191–198. doi: 10.1007/s12550-012-0134-y.
- Cramer, B., and Humpf, H. . “Applications of HPLC-MS techniques for the analysis of chemical contaminants and residues in food.” in Chemical Contaminants and Residues in Food, Vol. null , edited by D Schrenk. Elsevier. doi: 10.1533/9780857095794.1.62.
- Von, Bargen K., Lohrey, L., Cramer, B., and Humpf, H. . “Analysis of the Fusarium mycotoxin moniliformin in cereal samples using 13C 2-moniliformin and high-resolution mass spectrometry.” Journal of Agricultural and Food Chemistry 60 (14): 3586–3591. doi: 10.1021/jf300323d.
- Vessecchi, R., Julião, Zocolo G., Rubio, Gouvea D., Hübner, F., Cramer, B., Rodrigues, DeMarchi M., Humpf, H., and Lopes, N. . “Re-examination of the anion derivatives of isoflavones by radical fragmentation in negative electrospray ionization tandem mass spectrometry: Experimental and computational studies.” Rapid Communications in Mass Spectrometry 25 (14): 2020–2026. doi: 10.1002/rcm.5075.
- Wu, Q., Lohrey, L., Cramer, B., Yuan, Z., and Humpf, H. . “Impact of physicochemical parameters on the decomposition of deoxynivalenol during extrusion cooking of wheat grits.” Journal of Agricultural and Food Chemistry 59 (23): 12480–12485. doi: 10.1021/jf2038604.
- Cramer, B, Harrer, H, Nakamura, K, Uemura, D, and Humpf, HU. . “Total synthesis and cytotoxicity evaluation of all ochratoxin A stereoisomers.” Bioorganic & Medicinal Chemistry 18 (1): 343–357. doi: 10.1016/j.bmc.2009.10.050.
- Pfeiffer, E, Hildebrand, A, Damm, G, Rapp, A, Cramer, B, Humpf, HU, and Metzler, M. . “Aromatic hydroxylation is a major metabolic pathway of the mycotoxin zearalenone in vitro.” Molecular Nutrition and Food Research 53 (9): 1123–1133. doi: 10.1002/mnfr.200800584.
- Cramer, B, Konigs, M, and Humpf, HU. . “Identification and in vitro cytotoxicity of ochratoxin a degradation products formed during coffee roasting.” Journal of Agricultural and Food Chemistry 56 (14): 5673–5681. doi: 10.1021/jf801296z.
- Cramer, B, Bretz, M, and Humpf, HU. . “Stable isotope dilution analysis of the Fusarium mycotoxin zearalenone.” Journal of Agricultural and Food Chemistry 55 (21): 8353–8358. doi: 10.1021/jf0717283.
- Bretz, M, Beyer, M, Cramer, B, Knecht, A, and Humpf, HU. . “Thermal degradation of the Fusarium mycotoxin deoxynivalenol.” Journal of Agricultural and Food Chemistry 54 (17): 6445–6451. doi: 10.1021/jf061008g.
- Knecht, A, Cramer, B, and Humpf, HU. . “New Monascus metabolites: Structure elucidation and toxicological properties studied with immortalized human kidney epithelial cells.” Molecular Nutrition and Food Research 50 (3): 314–321. doi: 10.1002/mnfr.200500229.
- Bretz, M, Beyer, M, Cramer, B, and Humpf, HU. . “Stable isotope dilution analysis of the Fusarium mycotoxins deoxynivalenol and 3-acetyldeoxynivalenol.” Molecular Nutrition and Food Research 50 (3): 251–260. doi: 10.1002/mnfr.200500230.
- Bretz, M, Beyer, M, Cramer, B, and Humpf, HU. . “Synthesis of stable isotope labeled 3-acetyldeoxynivalenol.” Molecular Nutrition and Food Research 49 (12): 1151–1153. doi: 10.1002/mnfr.200500153.