Professor Dr. Hans-Ulrich Humpf

Professur für Lebensmittelchemie (Prof. Humpf)
Professor Dr. Hans-Ulrich Humpf

Corrensstr. 45
48149 Münster

Akademische Profile

Externes Profil

  • Forschungsschwerpunkte

    • Untersuchungen zur thermischen Stabilität, zur Biosynthese, zur Toxizität und zum (intestinalen) Metabolismus von Mykotoxinen.
    • Entwicklung von humanen Biomonitoringmethoden (HBM) zur Expositionsabschätzung von Mykotoxinen sowie zum Nachweis von Ernährungsbiomarkern.
    • Metabolomics- und Proteomics-basierte Ansätze zur Charakterisierung zellulärer Antworten auf die Exposition mit Mykotoxinen und anderen Lebensmittelinhaltsstoffen
    • Transfer von Lebensmittelinhaltsstoffen an der intestinalen Barriere (Caco-2 Modell) und an der Blut-Hirn-Schranke.
    • Untersuchungen zum Vorkommen und zur Bedeutung von Mykotoxinen in Innenräumen
  • Vita

    Akademische Ausbildung

    Habilitation und Erlangung der Venia legendi im Fachgebiet "Lebensmittelchemie"
    Forschungsaufenthalt an der Emory University, Atlanta, USA, Department of Biochemistry bei Herrn Prof. Dr. A.H. Merrill
    2. Ausbildungsphase für Lebensmittelchemiker am Landesuntersuchungsamt in Erlangen, Staatsprüfung für Lebensmittelchemiker
    Dissertation am Lehrstuhl für Lebensmittelchemie der Universität Würzburg bei Prof. Dr. P. Schreier

    Beruflicher Werdegang

    Dekan des Fachbereichs Chemie und Pharmazie der Westfälischen Wilhelms-Universität Münster
    Geschäftsführender Direktor des Instituts für Lebensmittelchemie
    W3-Professur für Lebensmittelchemie an der Westfälischen Wilhelms-Universität Münster
    C3 Professur für Lebensmittelchemie an der Westfälischen Wilhelms-Universität Münster
    Wissenschaftlicher Assistent und seit 01.10.2000 Oberassistent am Lehrstuhl für Lebensmittelchemie der Universität Würzburg
    Post-doc an der Columbia University, New York, Department of Chemistry bei Prof. Dr. K. Nakanishi
    Wissenschaftlicher Mitarbeiter am Lehrstuhl für Lebensmittelchemie der Universität Würzburg

    Preise

    Josef-Schormüller-Stipendium – Lebensmittelchemische Gesellschaft (LChG) - Fachgruppe in der Gesellschaft Deutscher
    Studienabschluss-Stipendium – Fonds der Chemischen Industrie (FCI)
    Stockmeyer Wissenschaftspreis 2002 – Heinrich-Stockmeyer-Stiftung
    Peter B. Czedik-Eysenberg-Preis – GÖCH - Gesellschaft Österreichischer Chemiker - Arbeitsgruppe Lebensmittel, Kosmetik und Gebrauchsgegenstände

    Mitgliedschaften und Aktivitäten in Gremien

    Bundesinstitut für Risikobewertung (BfR) (BfR-Kommission für Kontaminanten in der Lebensmittelkette, Mitglied)
    Gesellschaft für Mykotoxinforschung e.V. (Präsident)
    Wiley-VCH (Editor in Chief der Zeitschrift "Molecular Nutrition and Food-Research")
    Mitglied in der der Senatskommission der Deutschen Forschungsgemeinschaft zur gesundheitlichen Bewertung von Lebensmitteln (SKLM)
    Präsident der Gesellschaft für Mykotoxinforschung e.V.
    Bundesinstitut für Risikobewertung (BFR) (Expertenkommission „Kontaminanten und andere gesundheitlich unerwünschte Stoffe in der Lebensmittelkette“, Mitglied)
    Associate Editor der Zeitschrift "Molecular Nutrition and Food-Research", Wiley-VCH
    Mitglied der Gesellschaft für Mykotoxinforschung e.V.
    Mitglied in der American Chemical Society
    Mitglied in der Gesellschaft Deutscher Chemiker GDCh

    Rufe

    wwu muenster, Lebensmittelchemie (W3) – angenommen
    Universität Hamburg, Lebensmittelchemie (C4) – abgelehnt
    Martin-Luther-Universität Halle-Wittenberg, Lebensmittelchemie (C4) – abgelehnt
    wwu muenster, Lebensmittelchemie (C3) – angenommen
    Universität Hohenheim, Lebensmittelchemie (C3) – abgelehnt
  • Lehre

  • Publikationen

    • Gerdemann A; Broenhorst M; Behrens M; Humpf HU; Esselen M. . ‘Polyphenols Cause Structure Dependent Effects on the Metabolic Profile of Human Hepatocarcinogenic Cells.Molecular Nutrition and Food Research 67, Nr. 21: e2300052. doi: 10.1002/mnfr.202300052.
    • Kleinehr J; Schöfbänker M; Daniel K; Günl F; Mohamed FF; Janowski J; Brunotte L; Boergeling Y; Liebmann M; Behrens M; Gerdemann A; Klotz L; Esselen M; Humpf HU; Ludwig S; Hrincius ER. . ‘Glycolytic interference blocks influenza A virus propagation by impairing viral polymerase-driven synthesis of genomic vRNA.PLoS Pathogens 19, Nr. 7: e1010986. doi: 10.1371/journal.ppat.1010986.
    • Patnana P.K.; Liu L.; Frank D.; Nimmagadda S.; Behrens M.; Ahmed H.; Xie X.; Liebmann M.; Wei L.; Gerdemann A.; Thivakaran A.; Humpf H.U.; Klotz L.; Dugas M.; Varghese J.; Trajkovic-Arsic M.; Siveke J.T.; Hanenberg H.; Opalka B.; Dührsen U.; Reinhardt H.C.; Guenther U.; von Bubnoff N.; Khandanpour C. . ‘Dose-dependent expression of GFI1 alters metabolism in the haematopoietic progenitors and MLL::AF9-induced leukaemic cells.’ British Journal of Haematology 202, Nr. 5: 1033–1048. doi: 10.1111/bjh.18939.
    • Lins, A.; Keuter, L.; Mulac, D.; Humpf; H.-U.; Langer, K.Role of stabilizers in protein adsorption patterns of PLGA nanoparticles.“ contributed to the DPhG Annual Meeting, Tübingen, .
    • Gerdemann, A; Cramer, B; Degen, G H; Veerkamp, J; Günther, G; Albrecht, W; Behrens, M; Esselen, M; Ghallab, A; Hengstler, J G; Humpf, H-U. . ‘Comparative metabolism of aflatoxin B1 in mouse, rat and human primary hepatocytes using HPLC–MS/MS.’ Archives of Toxicology 97, Nr. 12: 3179–3196. doi: 10.1007/s00204-023-03607-z.
    • Nikmaram, N.; Brückner, L.; Cramer, B.; Humpf, H.-U.; Keener, K. . ‘Degradation products of aflatoxin M1 (AFM1) formed by high voltage atmospheric cold plasma (HVACP) treatment.’ Toxicon 230. doi: 10.1016/j.toxicon.2023.107160.
    • Lipinski, S.; Lindekamp, N.; Funck, N.; Cramer, B.; Humpf, H.-U. . ‘Determination of furan and alkylfuran in breakfast cereals from the European market and their correlation with acrylamide levels.’ European Food Research and Technology 2023. doi: 10.1007/s00217-023-04374-y.
    • Kyei, N.N.A.; Waid, J.L.; Ali, N.; Cramer, B.; Humpf, H.-U.; Gabrysch, S. . ‘Maternal exposure to multiple mycotoxins and adverse pregnancy outcomes: a prospective cohort study in rural Bangladesh.’ Archives of Toxicology 97, Nr. 6: 1795–1812. doi: 10.1007/s00204-023-03491-7.

    • Hahn M, Lindemann V, Behrens M, Mulac D, Langer K, Esselen M, Humpf HU. . ‘Permeability of dopamine D2 receptor agonist hordenine across the intestinal and blood-brain barrier in vitro.PloS one 17, Nr. 6: e0269486. doi: 10.1371/journal.pone.0269486.
    • Gerdemann A; Behrens M; Esselen M; Humpf HU. . ‘Metabolic profiling as a powerful tool for the analysis of cellular alterations caused by 20 mycotoxins in HepG2 cells.Archives of Toxicology 96, Nr. 11: 2983–2998. doi: 10.1007/s00204-022-03348-5.
    • Kyei, N.N.A.; Cramer, B., Humpf, H.-U.; Degen, G.H.; Ali, N.; Gabrysch, S. . ‘Assessment of multiple mycotoxin exposure and its association with food consumption: a human biomonitoring study in a pregnant cohort in rural Bangladesh.Archives of Toxicology 96, Nr. 7: 2123–2138. doi: 10.1007/s00204-022-03288-0.
    • Eisenbrand G, Baum M, Cartus AT, Diel P, Engel KH, Engeli B, Epe B, Grune T, Guth S, Haller D, Heinz V, Hellwig M, Hengstler JG, Henle T, Humpf HU, Joost HG, Jäger H, Lachenmeier DW, Kulling S, Leist M, Lampen A, Marko D, Mally A, Röhrdanz E, Nöthlings U, Spranger J, Roth A, Vieths S, Stadler R, Steinberg P, Wätjen W. . ‘Salivary nitrate/nitrite and acetaldehyde in humans: potential combination effects in the upper gastrointestinal tract and possible consequences for the in vivo formation of N-nitroso compounds-a hypothesis.Archives of Toxicology 96, Nr. 6: 1905–1914. doi: 10.1007/s00204-022-03296-0.
    • Lindemann V, Schleiner T, Maier U, Fels H, Cramer B, Humpf HU. . ‘Analysis of mold and mycotoxins in naturally infested indoor building materials.Mycotoxin Research 2022. doi: 10.1007/s12550-022-00461-3.
    • Puel, O; Cramer, B.; Oswald, I.P.; Humpf, H.-U. . ‘From the laboratory bench to the lecture hall: latest findings from mycotoxin research presented at the 43rd Mycotoxin Workshop.Mycotoxin Research 2022. doi: 10.1007/s12550-022-00462-2.
    • Kasimir M, Behrens M, Humpf HU. . ‘C Lignin in the Pig Cecum Model.Journal of Agricultural and Food Chemistry 70, Nr. 27: 8317–8325. doi: 10.1021/acs.jafc.2c02836.
    • Lindemann V, Jagels A, Behrens M, Hübner F, Humpf HU. . ‘.In Vitro Metabolism of Phenylspirodrimanes Derived from the Indoor Fungus Stachybotrys.’ Toxins 14, Nr. 6: 395. doi: 10.3390/toxins14060395.
    • Lindemann V, Schmidt J, Cramer B, Humpf HU. . ‘Detection of Mycotoxins in Highly Matrix-Loaded House-Dust Samples by QTOF-HRMS, IM-QTOF-HRMS, and TQMS: Advantages and Disadvantages.Analytical Chemistry 94, Nr. 10: 4209–4217. doi: 10.1021/acs.analchem.1c04254.
    • Gerhard MN; Schymanski D; Ebner I; Esselen M; Stahl T; Humpf HU. . ‘Can the presence of additives result in false positive errors for microplastics in infant feeding bottles?Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 39, Nr. 1: 185–197. doi: 10.1080/19440049.2021.1989498.
    • Müller L, Keuter L, Bücksteeg D, Uebel T, Wilken M, Schürmann L, Behrens M, Humpf H, Esselen M. . ‘Metabolic conjugation reduces in vitro toxicity of the flavonoid nevadensin.’ Food and Chemical Toxicology 164: 113006. doi: 10.1016/j.fct.2022.113006.
    • Penczynski K, Cramer B, Dietrich S, Humpf H, Abraham K, Weikert C. . ‘Mycotoxins in Serum and 24-h Urine of Vegans and Omnivores from the Risks and Benefits of a Vegan Diet (RBVD) Study.’ Molecular Nutrition and Food Research 66, Nr. 6. doi: 10.1002/mnfr.202100874.
    • Lindemann V, Schmidt J, Cramer B, Humpf H. . ‘Detection of Mycotoxins in Highly Matrix-Loaded House-Dust Samples by QTOF-HRMS, IM-QTOF-HRMS, and TQMS: Advantages and Disadvantages.’ Analytical Chemistry 94, Nr. 10: 4209–4217. doi: 10.1021/acs.analchem.1c04254.
    • Jürgens FM, Behrens M, Humpf H-U, Robledo SM, Schmidt TJ. . ‘In Vitro Metabolism of Helenalin Acetate and 11α,13-Dihydrohelenalin Acetate: Natural Sesquiterpene Lactones from Arnica.’ Metabolites 12: 88. doi: 10.3390/metabo12010088.
    • Barth C., Spreen H., Mulac D., Keuter L., Behrens M., Humpf H.-U., Langer K. . ‘Spacer length and serum protein adsorption affect active targeting of trastuzumab-modified nanoparticles.Biomaterials and Biosystems 5: 100032. doi: 10.1016/j.bbiosy.2021.100032.
    • Hassan R.; Friebel A.; Brackhagen L.; Hobloss Z.; Myllys M.; González D.; Albrecht W.; Mohammed E.S.I.; Seddek A.l.; Marchan R.; Cadenas C.; Cramer B.; Humpf H.U.; Hartl L.; Simbrunner B.; Reiberger T.; Trauner M.; Hoehme S.; Degen G.H.; Hengstler J.G.; Ghallab A. . ‘Hypoalbuminemia affects the spatio-temporal tissue distribution of ochratoxin A in liver and kidneys: consequences for organ toxicity.’ Archives of Toxicology 96, Nr. 11: 2967–2981. doi: 10.1007/s00204-022-03361-8.
    • Hassan R.; González D.; Hobloss Z.; Brackhagen L.; Myllys M.; Friebel A.; Seddek A.l.; Marchan R.; Cramer B.; Humpf H.U.; Hoehme S.; Degen G.H.; Hengstler J.G.; Ghallab A. . ‘Inhibition of cytochrome P450 enhances the nephro- and hepatotoxicity of ochratoxin A.’ Archives of Toxicology 96, Nr. 12: 3349–3361. doi: 10.1007/s00204-022-03395-y.
    • Jürgens Michaela Franziska , Behrens Matthias , Humpf Hans-Ulrich , Robledo M. Sara , Schmidt J. Thomas. . ‘In Vitro Metabolism of Helenalin Acetate and 11α,13-Dihydrohelenalin Acetate: Natural Sesquiterpene Lactones from Arnica.’ Metabolites 12, Nr. 1: 88. doi: 10.3390/metabo12010088.

    • Lünne F; Köhler J; Stroh C; Müller L; Daniliuc CG; Mück-Lichtenfeld C; Würthwein EU; Esselen M; Humpf HU; Kalinina SA. . ‘Insights into Ergochromes of the Plant Pathogen Claviceps purpurea.Journal of Natural Products 84, Nr. 10: 2630–2643. doi: 10.1021/acs.jnatprod.1c00264.
    • Detzner J, Püttmann C, Pohlentz G, Humpf HU, Mellmann A, Karch H, Müthing J. . ‘Primary Human Colon Epithelial Cells (pHCoEpiCs) Do Express the Shiga Toxin (Stx) Receptor Glycosphingolipids Gb3Cer and Gb4Cer and Are Largely Refractory but Not Resistant towards Stx.’ International Journal of Molecular Sciences (IJMS) 22, Nr. 18: 10002. doi: 10.3390/ijms221810002.
    • Detzner J, Klein AL, Pohlentz G, Krojnewski E, Humpf HU, Mellmann A, Karch H, Müthing J. . ‘Primary Human Renal Proximal Tubular Epithelial Cells (pHRPTEpiCs): Shiga Toxin (Stx) Glycosphingolipid Receptors, Stx Susceptibility, and Interaction with Membrane Microdomains.’ Toxins 13, Nr. 8: 529.
    • Behrens M, Hüwel S, Galla H-J, Humpf H-U. . ‘Efflux at the Blood-Brain Barrier Reduces the Cerebral Exposure to Ochratoxin A, Ochratoxin α, Citrinin and Dihydrocitrinone.’ Toxins 13, Nr. 5: 327. doi: 10.3390/toxins13050327.
    • Detzner J, Krojnewski E, Pohlentz G, Steil D, Humpf HU, Mellmann A, Karch H, Müthing J. . ‘Shiga Toxin (Stx)-Binding Glycosphingolipids of Primary Human Renal Cortical Epithelial Cells (pHRCEpiCs) and Stx-Mediated Cytotoxicity.’ Toxins 13, Nr. 2: 139. doi: 10.3390/toxins13020139.
    • Kalinina S, Cramer B, Humpf H. . ‘Current and future perspectives of mycotoxin research — report from the 42nd Mycotoxin Workshop (Online conference).’ Mycotoxin Research 37, Nr. 4: 275–278. doi: 10.1007/s12550-021-00439-7.
    • Spreen H., Barth C., Keuter L., Behrens M., Humpf H.U., Langer K.Studies on the formation of a protein corona on colloidal drug carriers. contributed to the EMBO practical course – targeted proteomics: Experimental design and data analysis., CRG – Centre de Regulació Genòmica, online, .
    • Spreen H., Behrens M., Mulac D., Humpf H.U., Langer K.Nanoparticle matrix and incubation medium – main influencer of the protein corona? contributed to the DPhG Annual Meeting, Leipzig online, .
    • Schmidt J, Cramer B, Turner PC, Stoltzfus RJ, Humphrey JH, Smith LE, Humpf H-. . ‘Determination of urinary mycotoxin biomarkers using a sensitive online solid phase extraction‐uhplc‐ms/ms method.’ Toxins 13, Nr. 6. doi: 10.3390/toxins13060418.
    • Spreen H., Behrens M., Mulac D., Humpf H., Langer K. . ‘Identification of main influencing factors on the protein corona composition of PLGA and PLA nanoparticles.’ European journal of pharmaceutics and biopharmaceutics 163: 212–222.
    • Schmidt J, Lindemann V, Olsen M, Cramer B, Humpf H-U. . ‘Dried urine spots as sampling technique for multi-mycotoxin analysis in human urine.’ Mycotoxin Research 37, Nr. 2: 129–140. doi: 10.1007/s12550-021-00423-1.
    • Ghallab A, Hassan R, Myllys M, Albrecht W, Friebel A, Hoehme S, Hofmann U, Seddek A-, Braeuning A, Kuepfer L, Cramer B, Humpf H-, Boor P, Degen GH, Hengstler JG. . ‘Subcellular spatio-temporal intravital kinetics of aflatoxin B1 and ochratoxin A in liver and kidney.’ Archives of Toxicology 95, Nr. 6: 2163–2177. doi: 10.1007/s00204-021-03073-5.
    • N. Kopp, G. Civenni, D. Marson, E. Laurini, S. Pricl, C. V. Catapano, H.-U. Humpf, C. Almansa, F. R. Nieto, D. Schepmann, B. Wünsch . . ‘Chemoenzymatic synthesis of 2,6-disubsttuted tetrahydropyrans with high 1 receptor affinity, antitumor and analgesic activity.European Journal of Medicinal Chemistry 219: 113443. doi: 10.1016/j.ejmech.2021.113443.
    • Haidar Samer , Jürgens Michaela Franziska , Aichele Dagmar , Jagels Annika , Humpf Hans-Ulrich , Jose Joachim. . ‘Natural Compounds Isolated from Stachybotrys chartarum Are Potent Inhibitors of Human Protein Kinase CK2.’ Molecules (Basel, Switzerland) 26, Nr. 15: 4453. doi: 10.3390/molecules26154453.

    • Jagels A, Stephan F, Ernst S, Lindemann V, Cramer B, Hübner F, Humpf H-U. . ‘Artificial vs natural Stachybotrys infestation—Comparison of mycotoxin production on various building materials.’ Indoor Air 30, Nr. 6: 1268–1282. doi: 10.1111/ina.12705.
    • Schulz M, Gaitanoglou V, Mantel O, Hoevelmann Y, Huebner F, Dobrindt U, Humpf HU. . ‘Metabolomics Study on Pathogenic and Non-pathogenic E. coli with Closely Related Genomes with a Focus on Yersiniabactin and Its Known and Novel Derivatives.’ Metabolites 10, Nr. 6: 221. doi: 10.3390/metabo10060221.
    • Kasimir Matthias, Behrens Matthias, Schulz Mareike, Kuchenbuch Henning, Focke Christine, Humpf Hans-Ulrich. . ‘Intestinal Metabolism of α- and β‑Glucosylated Modified Mycotoxins T‑2 and HT‑2 Toxin in the Pig Cecum Model.’ Journal of Agricultural and Food Chemistry 68, Nr. 19. doi: 10.1021/acs.jafc.0c00576.
    • Hövelmann Y, Lewin L, Steinert K, Hübner F, Humpf HU. . ‘Mass Spectrometry–Based Analysis of Urinary Biomarkers for Dietary Tomato Intake.’ Molecular Nutrition & Food Research 64.
    • Hövelmann Y, Steinert K, Hübner F, Humpf HU. . ‘Identification of a novel N-caprylhistamine-β-glucoside from tomato fruits and LC-MS/MS-based food screening for imidazole alkaloids.’ Food Chemistry 312.
    • Warensjö Lemming E, Montano Montes A, Schmidt J, Cramer B, Humpf H-, Moraeus L, Olsen M. . ‘Mycotoxins in blood and urine of Swedish adolescents—possible associations to food intake and other background characteristics.’ Mycotoxin Research 36, Nr. 2: 193–206. doi: 10.1007/s12550-019-00381-9.
    • Korff M, Imberg L, Will JM, Buckreis N, Kalinina SA, Wenzel BM, Kastner GA, Daniliuc CG, Barth M, Ovsepyan RA, Butov KR, Humpf HU, Lehr M, Panteleev MA, Poso A, Karst U, Stenmetzer T, Bendas G, Kalinin DV. . ‘Acylated 1H-1,2,4-Triazol-5-amines Targeting Human Coagulation Factor XIIa and Thrombin: Conventional and Microscale Synthesis, Anticoagulant Properties, and Mechanism of Action.’ Journal of Medicinal Chemistry 63, Nr. 21: 13159–13186. doi: 10.1021/acs.jmedchem.0c01635.
    • Marques LMM, Behrens M, Kalinina S, Rottkord U, Adhikari A, (S) Shrestha RL, Humpf H, Lopes NP. . ‘Govaniadine Evaluation of Cytotoxicity and Permeability in Cell Culture.’ Revista Brasileira de Farmacognosia 30, Nr. 3: 374–380. doi: 10.1007/s43450-020-00066-w.
    • Detzner J, Steil D, Pohlentz G, Legros N, Humpf HU, Mellmann A, Karch H, Muthing J. . ‘Real-time interaction analysis of Shiga toxins and membrane microdomains of primary human brain microvascular endothelial cells.’ Glycobiology 30, Nr. 3: 174–185. doi: 10.1093/glycob/cwz091.

    • Detzner J, Gloerfeld C, Pohlentz G, Legros N, Humpf HU, Mellmann A, Karch H, Muthing J. . ‘Structural Insights into Escherichia coli Shiga Toxin (Stx) Glycosphingolipid Receptors of Porcine Renal Epithelial Cells and Inhibition of Stx-Mediated Cellular Injury Using Neoglycolipid-Spiked Glycovesicles.’ Microorganisms 7, Nr. 11: 582. doi: 10.3390/microorganisms7110582.
    • Partikel K., Korte R., Stein N.C., Mulac D., Herrmann F.C., Humpf H.-U., Langer K. . ‘Effect of nanoparticle size and PEGylation on the protein corona of PLGA nanoparticles.Eur. J. Pharm. Biopharm. 2019: 70–80.
    • Partikel K., Korte R., Mulac D., Humpf H.-U., Langer K. . ‘Serum type and concentration both affecting the protein corona composition of PLGA nanoparticles.Beilstein J. Nanotechnol. 10: 1002–1015.
    • Sueck F, Hemp V, Specht J, Torres O, Cramer B, Humpf H-U. . ‘Occurrence of the ochratoxin A degradation product 2′R-ochratoxin a in coffee and other food: An update.’ Toxins 11, Nr. 6: 329. doi: 10.3390/toxins11060329.
    • Kuchenbuch HS, Cramer B, Humpf H-U. . ‘Matrix binding of T-2 toxin: structure elucidation of reaction products and indications on the fate of a relevant food-borne toxin during heating.’ Mycotoxin Research 35, Nr. 3: 261–270. doi: 10.1007/s12550-019-00350-2.
    • Sueck F, Cramer B, Czeschinski P, Humpf H-. . ‘Human Study on the Kinetics of 2′R-Ochratoxin A in the Blood of Coffee Drinkers.’ Molecular Nutrition and Food Research 63, Nr. 4: 1801026. doi: 10.1002/mnfr.201801026.
    • Kuchenbuch HS, Schulz M, Becker S, Cramer B, Humpf H-. . Thermal reactions and the formation of degradation products of T-2 and HT-2 toxin during processing of oats.: American Chemical Society. doi: 10.1021/bk-2019-1306.ch007.
    • Sueck F, Specht J, Cramer B, Humpf H-. . ‘Identification of ochratoxin-N-acetyl-L-cysteine as a new ochratoxin A metabolite and potential biomarker in human urine.’ Mycotoxin Research 2020, Nr. 36: 1–10. doi: 10.1007/s12550-019-00360-0.
    • Jagels A, Lindemann V, Ulrich S, Gottschalk C, Cramer B, Hübner F, Gareis M, Humpf H-U. . ‘Exploring secondary metabolite profiles of stachybotrys spp. By LC-MS/MS.’ Toxins 11, Nr. 3: 133. doi: 10.3390/toxins11030133.
    • Hövelmann Y, Lewin L, Hübner F, Humpf HU. . ‘Large-Scale Screening of Foods for Glucose-Derived β-Carboline Alkaloids by Stable Isotope Dilution LC–MS/MS.’ Journal of Agricultural and Food Chemistry 67: 3890–3899.
    • Hövelmann Y, Hahn M, Hübner F, Humpf HU. . ‘Detection of Novel Cytotoxic Imidazole Alkaloids in Tomato Products by LC-MS/MS.’ Journal of Agricultural and Food Chemistry 67: 3670–3678.
    • Hövelmann Y, Jagels A, Schmid R, Hübner F, Humpf HU. . ‘Identification of potential human urinary biomarkers for tomato juice intake by mass spectrometry-based metabolomics.’ European Journal of Nutrition 59: 685–697.
    • Faisal Zelma , Kunsági-Máté Sándor , Lemli Beáta , Szente Lajos , Bergmann Dominik , Humpf Hans-Ulrich , Poór Miklós. . ‘Interaction of Dihydrocitrinone with Native and Chemically Modified Cyclodextrins.’ Molecules (Basel, Switzerland) 24, Nr. 7: 1328. doi: 10.3390/molecules24071328.

    • Andreeßen C., Wolf N., Cramer B., Humpf H., Steinbüchel A. . ‘In vitro biosynthesis of 3-mercaptolactate by lactate dehydrogenases.’ Enzyme and Microbial Technology 108, Nr. null: 1–10. doi: 10.1016/j.enzmictec.2017.08.005.
    • Jagels A, Hövelmann Y, Zielinski A, Esselen M, Köhler J, Hübner F, Humpf HU. . ‘Stachybotrychromenes A-C: novel cytotoxic meroterpenoids from Stachybotrys sp.Mycotoxin Res. 34: 179–185.
    • Krug I, Behrens M, Esselen M, Humpf HU. . ‘Transport of enniatin B and enniatin B1 across the blood-brain barrier and hints for neurotoxic effects in cerebral cells.PloS one 13(5). doi: 10.1371/journal.pone.0197406.
    • Sueck F, Poór M, Faisal Z, Gertzen C, Cramer B, Lemli B, Kunsági-Máté S, Gohlke H, Humpf H-U. . ‘Interaction of ochratoxin A and its thermal degradation product 2'R-ochratoxin A with human serum albumin.’ Toxins 10, Nr. 7. doi: 10.3390/toxins10070256.
    • Schmidt HS, Schulz M, Focke C, Becker S, Cramer B, Humpf H-U. . ‘Glucosylation of T-2 and HT-2 toxins using biotransformation and chemical synthesis: Preparation, stereochemistry, and stability.’ Mycotoxin Research 34, Nr. 3: 159–172. doi: 10.1007/s12550-018-0310-9.
    • Kalinina SA, Jagels A, Hickert S, Mauriz Marques LM, Cramer B, Humpf H. . ‘Detection of the Cytotoxic Penitrems A-F in Cheese from the European Single Market by HPLC-MS/MS.’ Journal of Agricultural and Food Chemistry 66, Nr. 5: 1264–1269. doi: 10.1021/acs.jafc.7b06001.
    • Faisal Z, Derdák D, Lemli B, Kunsági-Máté S, Bálint M, Hetényi C, Csepregi R, Kőszegi T, Sueck F, Cramer B, Humpf H, Poór M. . ‘Interaction of 2'R-ochratoxin A with serum albumins: Binding site, effects of site markers, thermodynamics, species differences of albumin-binding, and influence of albumin on its toxicity in MDCK cells.’ Toxins 10, Nr. 9. doi: 10.3390/toxins10090353.
    • Bauer JI, Gross M, Cramer B, Humpf H, Hamscher G, Usleber E. . ‘Immunochemical Analysis of Paxilline and Ergot Alkaloid Mycotoxins in Grass Seeds and Plants.’ Journal of Agricultural and Food Chemistry 66, Nr. 1: 315–322. doi: 10.1021/acs.jafc.7b05580.
    • Faisal Zelma , Derdák Diána , Lemli Beáta , Kunsági-Máté Sándor , Bálint Mónika , Hetényi Csaba , Csepregi Rita , Koszegi Tamas , Sueck Franziska , Cramer Benedikt , Humpf Hans-Ulrich , Poór Miklós. . ‘Interaction of 2′R-ochratoxin A with Serum Albumins: Binding Site, Effects of Site Markers, Thermodynamics, Species Differences of Albumin-binding, and Influence of Albumin on Its Toxicity in MDCK Cells.’ Toxins 10, Nr. 9: 353. doi: 10.3390/toxins10090353.
    • Sueck, F.; Poór, M.; Faisal, Z.; Gertzen, C.G.W.; Cramer, B.; Lemli, B.; Kunsági-Máté, S.; Gohlke, H.; Humpf, H.-U. . . ‘Interaction of Ochratoxin A and Its Thermal Degradation Product 2′R-Ochratoxin A with Human Serum Albumin.’ Toxins 10, Nr. 7: 256. doi: 10.3390/toxins10070256.
    • Viegas S., Osteresch B., Almeida A., Cramer B., Humpf H., Viegas C. . ‘Enniatin B and ochratoxin A in the blood serum of workers from the waste management setting.’ Mycotoxin Research 34, Nr. 2: 85–90. doi: 10.1007/s12550-017-0302-1.

    • Hickert S., Hermes L., Marques L., Focke C., Cramer B., Lopes N., Flett B., Humpf H. . ‘Alternaria toxins in South African sunflower seeds: cooperative study.’ Mycotoxin Research 33, Nr. 4: 309–321. doi: 10.1007/s12550-017-0290-1.
    • Cramer B., Hübner F., Humpf H. . ‘Applications of High-Performance Liquid Chromatography-Mass Spectrometry Techniques for the Analysis of Chemical Contaminants and Residues in Food.’ In Chemical Contaminants and Residues in Food: Second Edition, edited by Schrenk D, 51–66. Elsevier Inc. doi: 10.1016/B978-0-08-100674-0.00003-5.
    • Schmidt H., Becker S., Cramer B., Humpf H. . ‘Impact of Mechanical and Thermal Energies on the Degradation of T-2 and HT-2 Toxins during Extrusion Cooking of Oat Flour.’ Journal of Agricultural and Food Chemistry 65, Nr. 20: 4177–4183. doi: 10.1021/acs.jafc.7b01484.
    • Kalinina S., Jagels A., Cramer B., Geisen R., Humpf H. . ‘Influence of environmental factors on the production of penitrems A–F by Penicillium crustosum.’ Toxins 9, Nr. 7. doi: 10.3390/toxins9070210.
    • Osteresch B., Viegas S., Cramer B., Humpf H. . ‘Multi-mycotoxin analysis using dried blood spots and dried serum spots.’ Analytical and Bioanalytical Chemistry 409, Nr. 13: 3369–3382. doi: 10.1007/s00216-017-0279-9.
    • Arndt B., Janevska S., Schmid R., Hübner F., Tudzynski B., Humpf H. . ‘A Fungal N-Dimethylallyltryptophan Metabolite from Fusarium fujikuroi.’ ChemBioChem 18, Nr. 10: 899–904. doi: 10.1002/cbic.201600691.
    • Legros N., Pohlentz G., Runde J., Dusny S., Humpf H., Karch H., Müthing J. . ‘Colocalization of receptors for Shiga toxins with lipid rafts in primary human renal glomerular endothelial cells and influence of D-PDMP on synthesis and distribution of glycosphingolipid receptors.’ Glycobiology 27, Nr. 10: 947–965. doi: 10.1093/glycob/cwx048.
    • Jarolim K., Del Favero G., Ellmer D., Stark T., Hofmann T., Sulyok M., Humpf H., Marko D. . ‘Dual effectiveness of Alternaria but not Fusarium mycotoxins against human topoisomerase II and bacterial gyrase.’ Archives of Toxicology 91, Nr. 4: 2007–2016. doi: 10.1007/s00204-016-1855-z.
    • Janevska S., Arndt B., Baumann L., Apken L., Marques L., Humpf H., Tudzynski B. . ‘Establishment of the inducible Tet-on system for the activation of the silent trichosetin gene cluster in Fusarium fujikuroi.’ Toxins 9, Nr. 4. doi: 10.3390/toxins9040126.
    • Studt L., Janevska S., Arndt B., Boedi S., Sulyok M., Humpf H., Tudzynski B., Strauss J. . ‘Lack of the COMPASS component Ccl1 reduces H3K4 trimethylation levels and affects transcription of secondary metabolite genes in two plant-pathogenic fusarium species.’ Frontiers in Microbiology 7, Nr. null. doi: 10.3389/fmicb.2016.02144.
    • Kouzel I., Pohlentz G., Schmitz J., Steil D., Humpf H., Karch H., Müthing J. . ‘Shiga toxin glycosphingolipid receptors in human Caco-2 and HCT-8 colon epithelial cell lines.’ Toxins 9, Nr. 11. doi: 10.3390/toxins9110338.
    • Humpf H., Schneider C., Stevens J. . ‘Hot Topics in 2017 – Gut Microbiota, Whole Grains and Health.’ Molecular Nutrition and Food Research 61, Nr. 1. doi: 10.1002/mnfr.201770014.
    • Rottkord U., Röhl C., Ferse I., Schulz M., Rückschloss U., Gekle M., Schwerdt G., Humpf H. . ‘Structure–activity relationship of ochratoxin A and synthesized derivatives: importance of amino acid and halogen moiety for cytotoxicity.’ Archives of Toxicology 91, Nr. 3: 1461–1471. doi: 10.1007/s00204-016-1799-3.
    • Saenger T., Hübner F., Humpf H. . ‘Short-term biomarkers of apple consumption.’ Molecular Nutrition and Food Research 61, Nr. 3. doi: 10.1002/mnfr.201600629.
    • Legros N., Dusny S., Humpf H., Pohlentz G., Karch H., Müthing J. . ‘Shiga toxin glycosphingolipid receptors and their lipid membrane ensemble in primary human blood-brain barrier endothelial cells.’ Glycobiology 27, Nr. 1: 99–109. doi: 10.1093/glycob/cww090.
    • Wu Q., Kuča K., Humpf H., Klímová B., Cramer B. . ‘Fate of deoxynivalenol and deoxynivalenol-3-glucoside during cereal-based thermal food processing: a review study.’ Mycotoxin Research 33, Nr. 1: 79–91. doi: 10.1007/s12550-016-0263-9.
    • Muñoz K., Cramer B., Dopstadt J., Humpf H., Degen G. . ‘Evidence of ochratoxin A conjugates in urine samples from infants and adults.’ Mycotoxin Research 33, Nr. 1: 39–47. doi: 10.1007/s12550-016-0261-y.
    • Dopstadt J., Vens-Cappell S., Neubauer L., Tudzynski P., Cramer B., Dreisewerd K., Humpf H. . ‘Localization of ergot alkaloids in sclerotia of Claviceps purpurea by matrix-assisted laser desorption/ionization mass spectrometry imaging.’ Analytical and Bioanalytical Chemistry 409, Nr. 5: 1221–1230. doi: 10.1007/s00216-016-0047-2.

    • Brezina U., Rempe I., Kersten S., Valenta H., Humpf H., Dänicke S. . ‘Determination of zearalenone, deoxynivalenol and metabolites in bile of piglets fed diets with graded levels of Fusarium toxin contaminated maize.’ World Mycotoxin Journal 9, Nr. 2: 179–193. doi: 10.3920/WMJ2015.1902.
    • Yamashita S., Bergmann D., Sato A., Nomoto M., Tada Y., Humpf H., Itami K., Hagihara S. . ‘High-throughput assay for quantification of aminoglycoside-Ribosome interaction.’ Chemistry Letters 45, Nr. 9: 1048–1050. doi: 10.1246/cl.160508.
    • Goldbeck C., Fürst P., Humpf H., Schymanski D. . ‘Kunststoffpartikel sind überall – auch in Lebensmitteln?Nachrichten aus der Chemie 64, Nr. 9: 842–846. doi: 10.1002/nadc.20164052892.
    • Havermann S., Humpf H., Wätjen W. . ‘Baicalein modulates stress-resistance and life span in C. elegans via SKN-1 but not DAF-16.’ Fitoterapia 113, Nr. null: 123–127. doi: 10.1016/j.fitote.2016.06.018.
    • Bernhardt K., Valenta H., Kersten S., Humpf H., Dänicke S. . ‘Determination of T-2 toxin, HT-2 toxin, and three other type A trichothecenes in layer feed by high-performance liquid chromatography-tandem mass spectrometry (LC-MS/MS)—comparison of two sample preparation methods.’ Mycotoxin Research 32, Nr. 2: 89–97. doi: 10.1007/s12550-016-0244-z.
    • Rösler S., Sieber C., Humpf H., Tudzynski B. . ‘Interplay between pathway-specific and global regulation of the fumonisin gene cluster in the rice pathogen Fusarium fujikuroi.’ Applied Microbiology and Biotechnology 100, Nr. 13: 5869–5882. doi: 10.1007/s00253-016-7426-7.
    • Studt L., Rösler S., Burkhardt I., Arndt B., Freitag M., Humpf H., Dickschat J., Tudzynski B. . ‘Knock-down of the methyltransferase Kmt6 relieves H3K27me3 and results in induction of cryptic and otherwise silent secondary metabolite gene clusters in Fusarium fujikuroi.’ Environmental Microbiology 18, Nr. 11: 4037–4054. doi: 10.1111/1462-2920.13427.
    • Havermann S., Chovolou Y., Humpf H., Wätjen W. . ‘Modulation of the Nrf2 signalling pathway in Hct116 colon carcinoma cells by baicalein and its methylated derivative negletein.’ Pharmaceutical Biology 54, Nr. 9: 1491–1502. doi: 10.3109/13880209.2015.1104703.
    • Korte R., Monneuse J., Gemrot E., Metton I., Humpf H., Brockmeyer J. . ‘New High-Performance Liquid Chromatography Coupled Mass Spectrometry Method for the Detection of Lobster and Shrimp Allergens in Food Samples via Multiple Reaction Monitoring and Multiple Reaction Monitoring Cubed.’ Journal of Agricultural and Food Chemistry 64, Nr. 31: 6219–6227. doi: 10.1021/acs.jafc.6b02620.
    • Humpf H., Schneider C., Stevens F. . ‘Obesity, Cancer and Nutrition, Gut Microbiota - Special Issues 2016.’ Molecular Nutrition and Food Research 60, Nr. 1: 5–6. doi: 10.1002/mnfr.201670014.
    • Rösler S., Kramer K., Finkemeier I., Humpf H., Tudzynski B. . ‘The SAGA complex in the rice pathogen Fusarium fujikuroi: structure and functional characterization.’ Molecular Microbiology 102, Nr. 6: 951–974. doi: 10.1111/mmi.13528.
    • Dopstadt J., Neubauer L., Tudzynski P., Humpf H. . ‘The epipolythiodiketopiperazine gene cluster in Claviceps purpurea: Dysfunctional cytochrome P450 enzyme prevents formation of the previously unknown clapurines.’ PloS one 11, Nr. 7. doi: 10.1371/journal.pone.0158945.
    • Hickert S., Cramer B., Letzel M., Humpf H. . ‘Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry imaging of ochratoxin A and fumonisins in mold-infected food.’ Rapid Communications in Mass Spectrometry 30, Nr. 23: 2508–2516. doi: 10.1002/rcm.7733.
    • Hövelmann Y., Hickert S., Cramer B., Humpf H. . ‘Determination of exposure to the alternaria mycotoxin tenuazonic acid and its isomer allo-tenuazonic acid in a German population by stable isotope dilution HPLC-MS3 .’ Journal of Agricultural and Food Chemistry 64, Nr. 34: 6641–6647. doi: 10.1021/acs.jafc.6b02735.
    • Osteresch B., Cramer B., Humpf H. . ‘Analysis of ochratoxin A in dried blood spots - Correlation between venous and finger-prick blood, the influence of hematocrit and spotted volume.’ Journal of Chromatography B 1020, Nr. null: 158–164. doi: 10.1016/j.jchromb.2016.03.026.
    • Simon H , Hoffmann G , Hubner F ,Humpf HU, Karst U. . ‘Electrochemical simulation of metabolic reactions of the secondary fungal metabolites alternariol and alternariol methyl ether.’ Analytical and Bioanalytical Chemistry 408, Nr. 10: 2471–2483.
    • Simon H., Hoffmann G., Hübner F., Humpf H., Karst U. . ‘Electrochemical simulation of metabolic reactions of the secondary fungal metabolites alternariol and alternariol methyl ether.’ Analytical and Bioanalytical Chemistry null, Nr. null: 1–13. doi: 10.1007/s00216-016-9344-z. [online first]
    • Wang M, Carver J, Phelan V, Sanchez L, Garg N, Peng Y, Nguyen D, Watrous J, Kapono C, Luzzatto-Knaan T, Porto C, Bouslimani A, Melnik A, Meehan M, Liu W, Crüsemann M, Boudreau P, Esquenazi E, Sandoval-Calderón M, Kersten R, Pace L, Quinn R, Duncan K, Hsu C, Floros D, Gavilan R, Kleigrewe K, Northen T, Dutton R, Parrot D, Carlson E, Aigle B, Michelsen C, Jelsbak L, Sohlenkamp C, Pevzner P, Edlund A, McLean J, Piel J, Murphy B, Gerwick L, Liaw C, Yang Y, Humpf H, Maansson M, Keyzers R, Sims A, Johnson A, Sidebottom A, Sedio B, Klitgaard A, Larson C, Boya C, Torres-Mendoza D, Gonzalez D, Silva D, Marques L, Demarque D, Pociute E, O{'}Neill E, Briand E, Helfrich E, Granatosky E, Glukhov E, Ryffel F, Houson H, Mohimani H, Kharbush J, Zeng Y, Vorholt J, Kurita K, Charusanti P, McPhail K, Nielsen K, Vuong L, Elfeki M, Traxler M, Engene N, Koyama N, Vining O, Baric R, Silva R, Mascuch S, Tomasi S, Jenkins S, Macherla V, Hoffman T, Agarwal V, Williams P, Dai J, Neupane R, Gurr J, Rodríguez A, Lamsa A, Zhang C, Dorrestein K, Duggan B, Almaliti J, Allard P, Phapale P, Nothias L, Alexandrov T, Litaudon M, Wolfender J, Kyle J, Metz T, Peryea T, Nguyen D, VanLeer D, Shinn P, Jadhav A, Müller R, Waters K, Shi W, Liu X, Zhang L, Knight R, Jensen P, Palsson B, Pogliano K, Linington R, Gutiérrez M, Lopes N, Gerwick W, Moore B, Dorrestein P, Bandeira N. . ‘Sharing and community curation of mass spectrometry data with Global Natural Products Social Molecular Networking.’ Nature Biotechnology 34: 828–837. doi: 10.1038/nbt.3597.
    • Hickert S., Bergmann M., Ersen S., Cramer B., Humpf H. . ‘Survey of Alternaria toxin contamination in food from the German market, using a rapid HPLC-MS/MS approach.’ Mycotoxin Research 32, Nr. 1: 7–18. doi: 10.1007/s12550-015-0233-7.

    • Bittner Andrea ,Cramer Benedikt ,Harrer Henning, Humpf Hans-Ulrich. . ‘Structure elucidation and in vitro cytotoxicity of ochratoxin α amide, a new degradation product of ochratoxin A.’ Mycotoxin Research 31, Nr. 2: 83–90. doi: 10.1007/s12550-014-0218-y.
    • Steil D., Schepers C., Pohlentz G., Legros N., Runde J., Humpf H., Karch H., Müthing J. . ‘Shiga toxin glycosphingolipid receptors of Vero-B4 kidney epithelial cells and their membrane microdomain lipid environment.’ Journal of Lipid Research 56, Nr. 12: 2322–2336. doi: 10.1194/jlr.M063040.
    • Arndt B., Studt L., Wiemann P., Osmanov H., Kleigrewe K., Köhler J., Krug I., Tudzynski B., Humpf H. . ‘Genetic engineering, high resolution mass spectrometry and nuclear magnetic resonance spectroscopy elucidate the bikaverin biosynthetic pathway in Fusarium fujikuroi.’ Fungal Genetics and Biology 84, Nr. null: 26–36. doi: 10.1016/j.fgb.2015.09.006.
    • Hickert S., Krug I., Cramer B., Humpf H. . ‘Detection and Quantitative Analysis of the Non-cytotoxic allo-Tenuazonic Acid in Tomato Products by Stable Isotope Dilution HPLC-MS/MS.’ Journal of Agricultural and Food Chemistry 63, Nr. 50: 10879–10884. doi: 10.1021/acs.jafc.5b04812.
    • Hickert S., Gerding J., Ncube E., Hübner F., Flett B., Cramer B., Humpf H. . ‘A new approach using micro HPLC-MS/MS for multi-mycotoxin analysis in maize samples.’ Mycotoxin Research 31, Nr. 2: 109–115. doi: 10.1007/s12550-015-0221-y.
    • Gerding J., Ali N., Schwartzbord J., Cramer B., Brown D., Degen G., Humpf H. . ‘A comparative study of the human urinary mycotoxin excretion patterns in Bangladesh, Germany, and Haiti using a rapid and sensitive LC-MS/MS approach.’ Mycotoxin Research 31, Nr. 3: 127–136. doi: 10.1007/s12550-015-0223-9.
    • Bittner,Katharina M. K.M.,Kemme,Theresa T.,Peters,Katharina K.,Kersten,Susanne S.,Dänicke,Sven S.,Humpf,Hans Ulrich H.U.,. . ‘Systemic absorption and metabolism of dietary procyanidin B4 in pigs.’ Molecular Nutrition and Food Research 58, Nr. 12: 2273. doi: 10.1002/mnfr.201400435.
    • Humpf,Hans Ulrich H.U.,Schneider,Claus C.,Stevens,Jan Frederik J.F.,. . ‘Scoping dietary supplements versus botanical medicines.’ Molecular Nutrition and Food Research 59, Nr. 1: 6. doi: 10.1002/mnfr.201570004.
    • Habermeyer,Michael M.,Roth,Angelika A.,Guth,Sabine E. S.E.,Diel,Patrick P.,Engel,Karl Heinz K.H.,Epe,Bernd B.,Fürst,Peter P.,Heinz,Volker V.,Humpf,Hans Ulrich H.U.,Joost,Hans Georg H.G.,Knorr,Dietrich D.,De Kok,Theo Martinus C M T.M.C.M.,Kulling,Sabine E. S.E.,Lampen,Alfonso D. A.D.,Marko,Doris D.,Rechkemmer,Gerhard R. G.R.,Rietjens,Ivonne M C M I.M.C.M.,Stadler,Richard H. R.H.,Vieths,Stefan S.,Vogel,Rudi F. R.F.,Steinberg,Pablo P.,Eisenbrand,Gerhard G.,. . ‘Nitrate and nitrite in the diet: How to assess their benefit and risk for human health.’ Molecular Nutrition and Food Research 59, Nr. 1: 128. doi: 10.1002/mnfr.201400286.
    • Gerding,Johannes J.,Cramer,Benedikt B.,Humpf,Hans Ulrich H.U.,. . ‘Determination of mycotoxin exposure in Germany using an LC-MS/MS multibiomarker approach.’ Molecular Nutrition and Food Research 58, Nr. 12: 2368. doi: 10.1002/mnfr.201400406.
    • Behrens M, Hüwel S, Galla H, Humpf H. . ‘Blood-Brain Barrier Effects of the Fusarium Mycotoxins Deoxynivalenol, 3 Acetyldeoxynivalenol, and Moniliformin and Their Transfer to the Brain.’ PloS one 10, Nr. 11: 1–20. doi: 10.1371/journal.pone.0143640.
    • Michielse C, Studt L, Janevska S, Sieber C, Arndt B, Espino J, Humpf H, Güldener U, Tudzynski B. . ‘The global regulator FfSge1 is required for expression of secondary metabolite gene clusters but not for pathogenicity in Fusarium fujikuroi.’ Environmental Microbiology 17: 2690–2708. doi: 10.1111/1462-2920.12592.

    • Hennemeier,Isabell I.,Humpf,Hans Ulrich H.U.,Gekle,Michael M.,Schwerdt,Gerald G.,. . ‘Role of microRNA-29b in the ochratoxin A-induced enhanced collagen formation in human kidney cells.’ Toxicology 324: 122. doi: 10.1016/j.tox.2014.07.012.
    • Von Bargen,Christoph C.,Brockmeyer,Jens J.,Humpf,Hans Ulrich H.U.,. . „Meat authentication: A new HPLC-MS/MS based method for the fast and sensitive detection of horse and pork in highly processed food.“ Journal of Agricultural and Food Chemistry 62, Nr. 39: 9435. doi: 10.1021/jf503468t.
    • Havermann,Susannah S.,Chovolou,Yvonni Y.,Humpf,Hans Ulrich H.U.,Wätjen,Wim W.,. . ‘Caffeic acid phenethylester increases stress resistance and enhances lifespan in Caenorhabditis elegans by modulation of the insulin-like DAF-16 signalling pathway.’ PloS one 9, Nr. 6. doi: 10.1371/journal.pone.0100256.
    • Sartori LR, Vessecchi R, Humpf HU, Da Costa FB, Lopes NP. . ‘A systematic investigation of the fragmentation pattern of two furanoheliangolide C-8 stereoisomers using electrospray ionization mass spectrometry.Rapid Communications in Mass Spectrometry 28, Nr. 7: 723. doi: 10.1002/rcm.6839.
    • Niehaus E.-M., von Bargen K.W., Espino J.J., Pfannmüller A., Humpf H.-U., Tudzynski B. . ‘Characterization of the fusaric acid gene cluster in Fusarium fujikuroi.Applied Microbiology and Biotechnology 98, Nr. 4: 1749. doi: 10.1007/s00253-013-5453-1.
    • Humpf HU, Wüst M, Hayen H,. . „Too shortsighted? Planned reform of the practical year in North Rhine-Westphalia | Zu kurz gedacht?: Geplante reform des praktischen jahres in NRW.“ Deutsche Lebensmittel-Rundschau 110, Nr. 1: 12.
    • Rychlik,Michael M.,Humpf,Hans Ulrich H.U.,Marko,Doris D.,Dänicke,Sven S.,Mally,Angela A.,Berthiller,Franz F.,Klaffke,Horst St H.S.,Lorenz,Nicole N.,. . ‘Proposal of a comprehensive definition of modified and other forms of mycotoxins including “masked” mycotoxins.’ Mycotoxin Research 30, Nr. 4: 205. doi: 10.1007/s12550-014-0203-5.
    • Harrer,Henning H.,Humpf,Hans Ulrich H.U.,Voss,Kenneth A. K.A.,. . ‘In vivo formation of N-acyl-fumonisin B1.’ Mycotoxin Research 31, Nr. 1: 40. doi: 10.1007/s12550-014-0211-5.
    • Humpf,Hans Ulrich H.U.,Schneider,Claus C.,Stevens,Jan Frederik J.F.,. . ‘Functional Food - Where do we go?Molecular Nutrition and Food Research 58, Nr. 1: 6. doi: 10.1002/mnfr.201470004.
    • Brezina,Ulrike U.,Rempe,Inga I.,Kersten,Susanne S.,Valenta,Hana H.,Humpf,Hans Ulrich H.U.,Dänicke,Sven S.,. . ‘Diagnosis of intoxications of piglets fed with Fusarium toxin-contaminated maize by the analysis of mycotoxin residues in serum, liquor and urine with LC-MS/MS.’ Archives of Animal Nutrition 68, Nr. 6: 447. doi: 10.1080/1745039X.2014.973227.
    • Brezina,Ulrike U.,Valenta,Hana H.,Rempe,Inga I.,Kersten,Susanne S.,Humpf,Hans Ulrich H.U.,Dänicke,Sven S.,. . ‘Development of a liquid chromatography tandem mass spectrometry method for the simultaneous determination of zearalenone, deoxynivalenol and their metabolites in pig serum.’ Mycotoxin Research 30, Nr. 3: 186. doi: 10.1007/s12550-014-0200-8.
    • Leucht K., Fischbeck A., Caj M., Liebisch G., Hartlieb E., Benes P., Fried M., Humpf H.-U., Rogler G., Hausmann M. . ‘Sphingomyelin and phosphatidylcholine contrarily affect the induction of apoptosis in intestinal epithelial cells.’ Molecular Nutrition and Food Research 58, Nr. 4: 782–798. doi: 10.1002/mnfr.201300369.
    • Guaratini T., Silva D.B., Bizaro A.C., Sartori L.R., Humpf H.-U., Lopes N.P., Costa-Lotufo L.V., Lopes J.L.C. . ‘In vitro metabolism studies of erythraline, the major spiroalkaloid from Erythrina verna.’ BMC Complementary and Alternative Medicine 14, Nr. null. doi: 10.1186/1472-6882-14-61.
    • Lohrey L., Uehara T.N., Tani S., Yamaguchi J., Humpf H.-U., Itami K. . ‘2,4- and 2,5-disubstituted arylthiazoles: Rapid synthesis by c-h coupling and biological evaluation.’ European Journal of Organic Chemistry null, Nr. null. doi: 10.1002/ejoc.201402129. [online first]
    • Unterberg M, Leffers L, Hübner F, Humpf H, Lepikhov K, Walter J, Ebert F, Schwerdtle T. . ‘Toxicity of arsenite and thio-DMAV after long-term (21 days) incubation of human urothelial cells: Cytotoxicity, genotoxicity and epigenetics.’ Toxicology Research 3: 456–464. doi: 10.1039/c4tx00036f.

    • Studt L, Humpf HU, Tudzynski B. . ‘Signaling governed by G proteins and cAMP is crucial for growth, secondary metabolism and sexual development in Fusarium fujikuroi.PloS one 8, Nr. 2: e58185. doi: 10.1371/journal.pone.0058185.
    • Weidner M, Hüwel S, Ebert F, Schwerdtle T, Galla HJ, Humpf HU. . ‘Influence of T-2 and HT-2 toxin on the blood-brain barrier in vitro: new experimental hints for neurotoxic effects.PloS one 8, Nr. 3: e60484. doi: 10.1371/journal.pone.0060484.
    • Studt L., Schmidt F.J., Jahn L., Sieber C.M.K., Connolly L.R., Niehaus E.-M., Freitag M., Humpf H.-U., Tudzynski B. . ‘Two histone deacetylases, FfHda1 and FfHda2, are important for Fusarium fujikuroi secondary metabolism and virulence.Applied and Environmental Microbiology 79, Nr. 24: 7719. doi: 10.1128/AEM.01557-13.
    • Bittner A, Cramer B, Humpf HU. . ‘Matrix binding of ochratoxin A during roasting.Journal of Agricultural and Food Chemistry 61, Nr. 51: 12737. doi: 10.1021/jf403984x.
    • von Bargen C, Dojahn J, Waidelich D, Humpf HU, Brockmeyer J. . ‘New sensitive high-performance liquid chromatography-tandem mass spectrometry method for the detection of horse and pork in halal beef.Journal of Agricultural and Food Chemistry 61, Nr. 49: 11986. doi: 10.1021/jf404121b.
    • Silva,Denise Brentan D.B.,Guaratini,Thais T.,Vessecchi,Ricardo L. R.L.,Lopes,Norberto Peporine N.P.,Cramer,Benedikt B.,Humpf,Hans Ulrich H.U.,Callegari Lopes,JoÃo Luis J.L.,. . ‘H2 unimolecular elimination in electrospray ionization mass spectrometry from erythraline, a spirocyclic alkaloid.’ European Journal of Mass Spectrometry 19, Nr. 5: 350. doi: 10.1255/ejms.1243.
    • von Bargen K.W., Niehaus E.-M., Bergander K., Brun R., Tudzynski B., Humpf H.-U. . ‘Structure elucidation and antimalarial activity of apicidin F: an apicidin-like compound produced by Fusarium fujikuroi.Journal of Natural Products 76, Nr. 11: 2136. doi: 10.1021/np4006053.
    • Holl K, Falck E, Köhler J, Schepmann D, Humpf HU, Brust P, Wünsch B. . ‘Synthesis, Characterization, and Metabolism Studies of Fluspidine Enantiomers.ChemMedChem 2013. doi: 10.1002/cmdc.201300322.
    • Bittner K, Rzeppa S, Humpf HU. . ‘Distribution and quantification of flavan-3-ols and procyanidins with low degree of polymerization in nuts, cereals, and legumes.Journal of Agricultural and Food Chemistry 61, Nr. 38: 9148. doi: 10.1021/jf4024728.
    • Humpf,Hans Ulrich H.U.,Cramer,Benedikt B.,. . ‘HPLC-MS/MS-analysis of Mycotoxins: Current applications and future perspectives.’ Journal of Plant Pathology 1, Nr. SUPPL: S1.39.
    • Niehaus E.-M., Kleigrewe K., Wiemann P., Studt L., Sieber C.M.K., Connolly L.R., Freitag M., Güldener U., Tudzynski B., Humpf H.-U. . ‘Genetic manipulation of the Fusarium fujikuroi fusarin gene cluster yields insight into the complex regulation and fusarin biosynthetic pathway.Chemistry and Biology 20, Nr. 8: 1055. doi: 10.1016/j.chembiol.2013.07.004.
    • Bergmann D, Hübner F, Humpf HU. . ‘Stable isotope dilution analysis of small molecules with carboxylic acid functions using 18O labeling for HPLC-ESI-MS/MS: analysis of fumonisin B1.Journal of Agricultural and Food Chemistry 61, Nr. 33: 7904. doi: 10.1021/jf4022702.
    • Wiemann P., Sieber C.M.K., von Bargen K.W., Studt L., Niehaus E.-M., Espino J.J., Huß K., Michielse C.B., Albermann S., Wagner D., Bergner S.V., Connolly L.R., Fischer A., Reuter G., Kleigrewe K., Bald T., Wingfield B.D., Ophir R., Freeman S., Hippler M., Smith K.M., Brown D.W., Proctor R.H., Münsterkötter M., Freitag M., Humpf H.-U., Güldener U., Tudzynski B. . ‘Deciphering the cryptic genome: genome-wide analyses of the rice pathogen Fusarium fujikuroi reveal complex regulation of secondary metabolism and novel metabolites.PLoS Pathogens 9, Nr. 6: e1003475. doi: 10.1371/journal.ppat.1003475.
    • Blaas N, Humpf HU. . ‘Structural profiling and quantitation of glycosyl inositol phosphoceramides in plants with Fourier transform mass spectrometry.Journal of Agricultural and Food Chemistry 61, Nr. 18: 4257. doi: 10.1021/jf4001499.
    • Harrer H, Laviad EL, Humpf HU, Futerman AH. . ‘Identification of N-acyl-fumonisin B1 as new cytotoxic metabolites of fumonisin mycotoxins.Molecular Nutrition and Food Research 57, Nr. 3: 516. doi: 10.1002/mnfr.201200465.
    • Weidner M, Lenczyk M, Schwerdt G, Gekle M, Humpf HU. . ‘Neurotoxic potential and cellular uptake of T-2 toxin in human astrocytes in primary culture.Chemical Research in Toxicology 26, Nr. 3: 347. doi: 10.1021/tx3004664.
    • Havermann,Susannah S.,Rohrig,Ricarda R.,Chovolou,Yvonni Y.,Humpf,Hans Ulrich H.U.,Wätjen,Wim W.,. . ‘Molecular effects of baicalein in Hct116 cells and Caenorhabditis elegans: Activation of the Nrf2 signaling pathway and prolongation of lifespan.’ Journal of Agricultural and Food Chemistry 61, Nr. 9: 2164. doi: 10.1021/jf304553g.
    • Engemann A, Focke C, Humpf HU. . ‘Intestinal formation of N-nitroso compounds in the pig cecum model.Journal of Agricultural and Food Chemistry 61, Nr. 4: 998–1005. doi: 10.1021/jf305040e.
    • Mulac D, Lepski S, Ebert F, Schwerdtle T, Humpf HU. . ‘Cytotoxicity and fluorescence visualization of ergot alkaloids in human cell lines.Journal of Agricultural and Food Chemistry 61, Nr. 2: 462. doi: 10.1021/jf304569q.
    • Lohrey,Lilia L.,Marschik,Stefanie S.,Cramer,Benedikt B.,Humpf,Hans Ulrich H.U.,. . ‘Large-scale synthesis of isotopically labeled 13C 2-tenuazonic acid and development of a rapid HPLC-MS/MS method for the analysis of tenuazonic acid in tomato and pepper products.’ Journal of Agricultural and Food Chemistry 61, Nr. 1: 120. doi: 10.1021/jf305138k.
    • Lohrey L, Marschik S, Cramer B, Humpf HU. . ‘Large-scale synthesis of isotopically labeled 13C2-tenuazonic acid and development of a rapid HPLC-MS/MS method for the analysis of tenuazonic acid in tomato and pepper products.Journal of Agricultural and Food Chemistry 61, Nr. 1: 114. doi: 10.1021/jf305138k.
    • Biedermann L, Mwinyi J, Scharl M, Frei P, Zeitz J, Kullak-Ublick G, Vavricka S, Fried M, Weber A, Humpf H, Peschke S, Jetter A, Krammer G, Rogler G. . ‘Bilberry ingestion improves disease activity in mild to moderate ulcerative colitis - An open pilot study.’ Journal of Crohn{'}s and Colitis 7: 271–279. doi: 10.1016/j.crohns.2012.07.010.
    • Silva D, Guaratini T, Vessecchi R, Lopes N, Cramer B, Humpf H, Callegari Lopes J. . ‘H2 unimolecular elimination in electrospray ionization mass spectrometry from erythraline, a spirocyclic alkaloid.’ European Journal of Mass Spectrometry 19: 345–350. doi: 10.1255/ejms.1243.
    • Leffers L, Unterberg M, Bartel M, Hoppe C, Pieper I, Stertmann J, Ebert F, Humpf H, Schwerdtle T. . ‘In vitro toxicological characterisation of the S-containing arsenic metabolites thio-dimethylarsinic acid and dimethylarsinic glutathione.’ Toxicology 305: 109–119. doi: 10.1016/j.tox.2013.01.007.
    • Lohrey L, Marschik S, Cramer B, Humpf H. . ‘Large-scale synthesis of isotopically labeled 13C 2-tenuazonic acid and development of a rapid HPLC-MS/MS method for the analysis of tenuazonic acid in tomato and pepper products.’ Journal of Agricultural and Food Chemistry 61: 114–120. doi: 10.1021/jf305138k.

    • Wiemann P, Albermann S, Niehaus EM, Studt L, von Bargen KW, Brock NL, Humpf HU, Dickschat JS, Tudzynski B. . ‘The Sfp-type 4'-phosphopantetheinyl transferase Ppt1 of Fusarium fujikuroi controls development, secondary metabolism and pathogenicity.PloS one 7, Nr. 5: e37519. doi: 10.1371/journal.pone.0037519.
    • Ferse I, Langlitz M, Kleigrewe K, Rzeppa S, Lenczyk M, Harrer H, Cramer B, Humpf HU. . ‘Isolation and structure elucidation of two new cytotoxic metabolites from red yeast rice.Natural Product Research 26, Nr. 20: 1914. doi: 10.1080/14786419.2011.639074.
    • von Bargen C, Hübner F, Cramer B, Rzeppa S, Humpf HU. . ‘Systematic approach for structure elucidation of polyphenolic compounds using a bottom-up approach combining ion trap experiments and accurate mass measurements.Journal of Agricultural and Food Chemistry 60, Nr. 45: 11274. doi: 10.1021/jf3030369.
    • Welsch T, Humpf HU. . ‘HT-2 toxin 4-glucuronide as new T-2 toxin metabolite: enzymatic synthesis, analysis, and species specific formation of T-2 and HT-2 toxin glucuronides by rat, mouse, pig, and human liver microsomes.Journal of Agricultural and Food Chemistry 60, Nr. 40: 10170. doi: 10.1021/jf302571y.
    • Kleigrewe K., Niehaus E.-M., Wiemann P., Tudzynski B., Humpf H.-U. . ‘New approach via gene knockout and single-step chemical reaction for the synthesis of isotopically labeled fusarin c as an internal standard for the analysis of this fusarium mycotoxin in food and feed samples.Journal of Agricultural and Food Chemistry 60, Nr. 34: 8350. doi: 10.1021/jf302534x.
    • Studt L, Troncoso C, Gong F, Hedden P, Toomajian C, Leslie JF, Humpf HU, Rojas MC, Tudzynski B. . ‘Segregation of secondary metabolite biosynthesis in hybrids of Fusarium fujikuroi and Fusarium proliferatum.Fungal Genetics and Biology 49, Nr. 7: 567. doi: 10.1016/j.fgb.2012.05.005.
    • Studt L, Wiemann P, Kleigrewe K, Humpf HU, Tudzynski B. . ‘Biosynthesis of fusarubins accounts for pigmentation of Fusarium fujikuroi perithecia.Applied and Environmental Microbiology 78, Nr. 12: 4468. doi: 10.1128/AEM.00823-12.
    • Weidner M, Welsch T, Hübner F, Schwerdt G, Gekle M, Humpf HU. . ‘Identification and apoptotic potential of T-2 toxin metabolites in human cells.Journal of Agricultural and Food Chemistry 60, Nr. 22: 5676. doi: 10.1021/jf300634k.
    • Kleigrewe K, Aydin F, Hogrefe K, Piecuch P, Bergander K, Würthwein EU, Humpf HU. . ‘Structure elucidation of new fusarins revealing insights in the rearrangement mechanisms of the Fusarium mycotoxin fusarin C.Journal of Agricultural and Food Chemistry 60, Nr. 21: 5497. doi: 10.1021/jf3009469.
    • Rzeppa S, Bittner K, Döll S, Dänicke S, Humpf HU. . ‘Urinary excretion and metabolism of procyanidins in pigs.Molecular Nutrition and Food Research 56, Nr. 4: 653. doi: 10.1002/mnfr.201100471.
    • von Bargen KW, Lohrey L, Cramer B, Humpf HU. . ‘Analysis of the Fusarium mycotoxin moniliformin in cereal samples using 13C2-moniliformin and high-resolution mass spectrometry.Journal of Agricultural and Food Chemistry 60, Nr. 14: 3586. doi: 10.1021/jf300323d.
    • Mulac D, Hüwel S, Galla HJ, Humpf HU. . ‘Permeability of ergot alkaloids across the blood-brain barrier in vitro and influence on the barrier integrity.Molecular Nutrition and Food Research 56, Nr. 3: 475. doi: 10.1002/mnfr.201100431.
    • Hübner F, Harrer H, Fraske A, Kneifel S, Humpf HU. . ‘Large scale purification of B-type fumonisins using centrifugal partition chromatography (CPC).Mycotoxin Research 28, Nr. 1: 37–43. doi: 10.1007/s12550-011-0114-7.
    • Engemann A, Hübner F, Rzeppa S, Humpf HU. . ‘Intestinal metabolism of two A-type procyanidins using the pig cecum model: detailed structure elucidation of unknown catabolites with Fourier transform mass spectrometry (FTMS).Journal of Agricultural and Food Chemistry 60, Nr. 3: 749. doi: 10.1021/jf203927g.
    • van Valen F, Harrer H, Hotfilder M, Dirksen U, Pap T, Gosheger G, Humpf HU, Jürgens H. . ‘A Novel Role of IGF1 in Apo2L/TRAIL-Mediated Apoptosis of Ewing Tumor Cells.Sarcoma 2012: 782970.
    • Kuczius T, Hummel M, Böhler O, Humpf HU. . ‘Development and applications of simultaneous immunochemical staining and serial detection of overlapping proteins in blotting procedures.Journal of Immunological Methods 386, Nr. 1-2: 70–7.
    • Storck W, Meisen I, Gianmoena K, Pläger I, Kouzel IU, Bielaszewska M, Haier J, Mormann M, Humpf HU, Karch H, Müthing J. . ‘Shiga toxin glycosphingolipid receptor expression and toxin susceptibility of human pancreatic ductal adenocarcinomas of differing origin and differentiation.Biological Chemistry 393, Nr. 8: 785–99. doi: 10.1515/hsz-2012-0165.
    • Betz J, Bauwens A, Kunsmann L, Bielaszewska M, Mormann M, Humpf HU, Karch H, Friedrich AW, Müthing J. . ‘Uncommon membrane distribution of Shiga toxin glycosphingolipid receptors in toxin-sensitive human glomerular microvascular endothelial cells.Biological Chemistry 393, Nr. 3: 133–47.
    • Von Bargen K, Lohrey L, Cramer B, Humpf H. . ‘Analysis of the Fusarium mycotoxin moniliformin in cereal samples using 13C 2-moniliformin and high-resolution mass spectrometry.’ Journal of Agricultural and Food Chemistry 60: 3586–3591. doi: 10.1021/jf300323d.
    • Hennemeier I, Humpf H, Gekle M, Schwerdt G. . ‘The food contaminant and nephrotoxin ochratoxin A enhances Wnt1 inducible signaling protein 1 and tumor necrosis factor-α expression in human primary proximal tubule cells.’ Molecular Nutrition and Food Research 56: 1375–1384. doi: 10.1002/mnfr.201200164.
    • Slot G, Rose K, Engemann A, Humpf H. . The pig cecum model - A powerful tool for studying the intestinal metabolism of flavonoids. 2012: American Chemical Society. doi: 10.1021/bk-2012-1093.ch027.

    • Kleigrewe K, Söhnel AC, Humpf HU. . ‘A new high-performance liquid chromatography-tandem mass spectrometry method based on dispersive solid phase extraction for the determination of the mycotoxin fusarin C in corn ears and processed corn samples.Journal of Agricultural and Food Chemistry 59, Nr. 19: 10470. doi: 10.1021/jf2026814.
    • Rzeppa S, Von Bargen C, Bittner K, Humpf HU. . ‘Analysis of Flavan-3-ols and procyanidins in food samples by reversed phase high-performance liquid chromatography coupled to electrospray ionization tandem mass spectrometry (RP-HPLC-ESI-MS/MS).Journal of Agricultural and Food Chemistry 59, Nr. 19: 10594. doi: 10.1021/jf202697j.
    • Mulac D, Grote AK, Kleigrewe K, Humpf HU. . ‘Investigation of the metabolism of ergot alkaloids in cell culture by fourier transformation mass spectrometry.Journal of Agricultural and Food Chemistry 59, Nr. 14: 7798. doi: 10.1021/jf2012024.
    • Mulac D, Humpf HU. . ‘Cytotoxicity and accumulation of ergot alkaloids in human primary cells.Toxicology 282, Nr. 3: 112. doi: 10.1016/j.tox.2011.01.019.
    • Wiese C, Grosse Maestrup E, Schepmann D, Grimme S, Humpf HU, Brust P, Wünsch B. . ‘Enantioselective σ1 receptor binding and biotransformation of the spirocyclic PET tracer 1'-benzyl-3-(3-fluoropropyl)-3H-spiro[[2]benzofuran-1,4'-piperidine].Chirality 23, Nr. 2: 148. doi: 10.1002/chir.20893.
    • Bauwens A, Bielaszewska M, Kemper B, Langehanenberg P, von Bally G, Reichelt R, Mulac D, Humpf HU, Friedrich AW, Kim KS, Karch H, Müthing J. . ‘Differential cytotoxic actions of Shiga toxin 1 and Shiga toxin 2 on microvascular and macrovascular endothelial cells.Thrombosis and Haemostasis 105, Nr. 3: 515. doi: 10.1160/TH10-02-0140.
    • Wiese C, Maestrup EG, Schepmann D, Grimme S, Humpf HU, Brust P, Wunsch B. . ‘Enantioselective sigma(1) Receptor Binding and Biotransformation of the Spirocyclic PET Tracer 1 '-Benzyl-3-(3-fluoropropyl)-3H-spiro[[2]benzofuran-1,4 '-piperidine].’ Chirality 23, Nr. 2: 148–154. doi: 10.1002/chir.20893.
    • Fischbeck A, Leucht K, Frey-Wagner I, Bentz S, Pesch T, Kellermeier S, Krebs M, Fried M, Rogler G, Hausmann M, Humpf HU. . ‘Sphingomyelin induces cathepsin D-mediated apoptosis in intestinal epithelial cells and increases inflammation in DSS colitis.’ Gut 60, Nr. 1: 55–65. doi: 10.1136/gut.2009.201988.
    • Betz J, Bielaszewska M, Thies A, Humpf HU, Dreisewerd K, Karch H, Kim KS, Friedrich AW, Müthing J. . ‘Shiga toxin glycosphingolipid receptors in microvascular and macrovascular endothelial cells: differential association with membrane lipid raft microdomains.Journal of Lipid Research 52, Nr. 4: 618–634. doi: 10.1194/jlr.M010819.
    • Franzmann C, Schröder J, Mϋnzing K, Wolf K, Lindhauer M, Humpf H. . ‘Distribution of ergot alkaloids and ricinoleic acid in different milling fractions.’ Mycotoxin Research 27: 13–21. doi: 10.1007/s12550-010-0070-7.
    • Wiese C, Maestrup E, Schepmann D, Grimme S, Humpf H, Brust P, Wünsch B. . ‘Enantioselective σ1 receptor binding and biotransformation of the spirocyclic PET tracer 1′-benzyl-3-(3-fluoropropyl)-3H-spiro[[2] benzofuran-1,4′-piperidine].’ Chirality 23: 148–154. doi: 10.1002/chir.20893.
    • Blaas N, Schüürmann C, Bartke N, Stahl B, Humpf H. . ‘Structural profiling and quantification of sphingomyelin in human breast milk by HPLC-MS/MS.’ Journal of Agricultural and Food Chemistry 59: 6018–6024. doi: 10.1021/jf200943n.
    • Lohrey L, Murata T, Uemura D, Humpf H. . ‘Synthesis of isotopically labeled fusarium mycotoxin 13C 2-moniliformin [1-hydroxycyclobut-1-ene-3,4-dione].’ SYNLETT 2011: 2242–2244. doi: 10.1055/s-0030-1261189.

    • Danicke S, Beyer M, Breves G, Valenta H, Humpf HU. . ‘Effects of oral exposure of pigs to deoxynivalenol (DON) sulfonate (DONS) as the non-toxic derivative of DON on tissue residues of DON and de-epoxy-DON and on DONS blood levels.’ Food Additives and Contaminants: Part A: Chemistry, Analysis, Control, Exposure and Risk Assessment 27, Nr. 11: 1558–1565. doi: 10.1080/19440049.2010.501036.
    • Danicke S, Pahlow G, Beyer M, Goyarts T, Breves G, Valenta H, Humpf HU. . ‘Investigations on the kinetics of the concentration of deoxynivalenol (DON) and on spoilage by moulds and yeasts of wheat grain preserved with sodium metabisulfite (Na2S2O5, SBS) and propionic acid at various moisture contents.’ Archives of Animal Nutrition 64, Nr. 3: 190–203. doi: 10.1080/17450391003693159.
    • Beyer M, Dänicke S, Rohweder D, Humpf H-U. . ‘Determination of Deoxynivalenol-sulfonate (DONS) in cereals by hydrophilic interaction chromatography coupled to tandem mass spectrometry.’ Mycotoxin Research 26, Nr. 2: 109–117. doi: 10.1007/s12550-010-0046-7.
    • Hasslauer I, Oehme A, Locher S, Valotis A, van't Slot G, Humpf HU, Schreier P. . ‘Flavan-3-ol C-glycosides - Preparation and model experiments mimicking their human intestinal transit.’ Molecular Nutrition and Food Research 54, Nr. 11: 1546–1555. doi: 10.1002/mnfr.201000003.
    • Wiemann P, Brown DW, Kleigrewe K, Bok JW, Keller NP, Humpf HU, Tudzynski B. . ‘FfVel1 and FfLae1, components of a velvet-like complex in Fusarium fujikuroi, affect differentiation, secondary metabolism and virulence.’ Molecular Microbiology 77, Nr. 4: 972–994. doi: 10.1111/j.1365-2958.2010.07263.x.
    • van't Slot G, Mattern W, Rzeppa S, Grewe D, Humpf HU. . ‘Complex Flavonoids in Cocoa: Synthesis and Degradation by Intestinal Microbiota.’ Journal of Agricultural and Food Chemistry 58, Nr. 15: 8879–8886. doi: 10.1021/jf1012242.
    • Franzmann C, Wachter J, Dittmer N, Humpf HU. . ‘Ricinoleic Acid as a Marker for Ergot Impurities in Rye and Rye Products.’ Journal of Agricultural and Food Chemistry 58, Nr. 7: 4223–4229. doi: 10.1021/jf1006903.
    • Hasche A, Ferenz KB, Rose K, König S, Humpf HU, Klumpp S, Krieglstein J. . ‘Binding of ATP to nerve growth factor: characterization and relevance for bioactivity.Neurochemistry International 56, Nr. 2: 276–84. doi: 10.1016/j.neuint.2009.10.012.
    • Cramer B, Harrer H, Nakamura K, Uemura D, Humpf HU. . ‘Total synthesis and cytotoxicity evaluation of all ochratoxin A stereoisomers.’ Bioorganic and Medicinal Chemistry 18, Nr. 1: 343–357. doi: 10.1016/j.bmc.2009.10.050.

    • Holl R, Jung B, Schepmann D, Humpf HU, Grunert R, Bednarski PJ, Englberger W, Wünsch B. . ‘Synthesis and Pharmacological Evaluation of SNC80 Analogues with a Bridged Piperazine Ring.’ ChemMedChem 4, Nr. 12: 2111–2122. doi: 10.1002/cmdc.200900358.
    • Beyer M, Ferse I, Humpf H-U. . ‘Large-scale production of selected type A trichothecenes: The use of HT-2 toxin and T-2 triol as precursors for the synthesis of d 3-T-2 and d 3-HT-2 toxin.’ Mycotoxin Research 25, Nr. 1: 41–52. doi: 10.1007/s12550-009-0006-2.
    • Fischbeck A, Kruger M, Blaas N, Humpf HU. . ‘Analysis of Sphingomyelin in Meat Based on Hydrophilic Interaction Liquid Chromatography Coupled to Electrospray Ionization-Tandem Mass Spectrometry (HILIC-HPLC-ESI-MS/MS).’ Journal of Agricultural and Food Chemistry 57, Nr. 20: 9469–9474. doi: 10.1021/jf9025376.
    • Pfeiffer E, Hildebrand A, Damm G, Rapp A, Cramer B, Humpf HU, Metzler M. . ‘Aromatic hydroxylation is a major metabolic pathway of the mycotoxin zearalenone in vitro.’ Molecular Nutrition and Food Research 53, Nr. 9: 1123–1133. doi: 10.1002/mnfr.200800584.
    • van't Slot G, Humpf HU. . ‘Degradation and Metabolism of Catechin, Epigallocatechin-3-gallate (EGCG), and Related Compounds by the Intestinal Microbiota in the Pig Cecum Model.’ Journal of Agricultural and Food Chemistry 57, Nr. 17: 8041–8048. doi: 10.1021/jf900458e.
    • Wiemann P, Willmann A, Straeten M, Kleigrewe K, Beyer M, Humpf HU, Tudzynski B. . ‘Biosynthesis of the red pigment bikaverin in Fusarium fujikuroi: genes, their function and regulation.’ Molecular Microbiology 72, Nr. 4: 931–946. doi: 10.1111/j.1365-2958.2009.06695.x.
    • Konigs M, Mulac D, Schwerdt G, Gekle M, Humpf HU. . ‘Metabolism and cytotoxic effects of T-2 toxin and its metabolites on human cells in primary culture.’ Toxicology 258, Nr. 2-3: 106–115. doi: 10.1016/j.tox.2009.01.012.
    • Schwerdt G, Konigs M, Holzinger H, Humpf HU, Gekle M. . ‘Effects of the mycotoxin fumonisin B-1 on cell death in human kidney cells and human lung fibroblasts in primary culture.’ Journal of Applied Toxicology 29, Nr. 2: 174–182. doi: 10.1002/jat.1398.
    • Beyer M, Ferse I, Mulac D, Wurthwein EU, Humpf HU. . ‘Structural Elucidation of T-2 Toxin Thermal Degradation Products and Investigations toward Their Occurrence in Retail Food.’ Journal of Agricultural and Food Chemistry 57, Nr. 5: 1867–1875. doi: 10.1021/jf803516s.
    • Trebstein A, Marschik S, Lauber U, Humpf HU. . ‘Acetonitrile: the better extractant for the determination of T-2 and HT-2 toxin in cereals using an immunoaffinity-based cleanup?European Food Research and Technology 228, Nr. 4: 519–529. doi: 10.1007/s00217-008-0959-y.
    • Schwerdt G, Holzinger H, Konigs M, Humpf HU, Gekle M. . ‘Effect of ochratoxin A on cell survival and collagen homeostasis in human mesangial cells in primary culture.’ Food and Chemical Toxicology 47, Nr. 1: 209–213. doi: 10.1016/j.fct.2008.11.001.
    • Aldick T, Bielaszewska M, Uhlin BE, Humpf HU, Wai SN, Karch H. . ‘Vesicular stabilization and activity augmentation of enterohaemorrhagic Escherichia coli haemolysin.Molecular Microbiology 71, Nr. 6: 1496–1508. doi: 10.1111/j.1365-2958.2009.06618.x.
    • Fischbeck A, Krüger M, Blaas N, Humpf HU. . ‘Analysis of sphingomyelin in different meat and fish based on normal phase high-performance liquid chromatography (NP-HPLC).’ J. Agric. Food Chem. 57: 9469–9474.
    • Trebstein A, Lauber U, Humpf H. . ‘Analysis of fusarium toxins via HPLC-MS/MS multimethods: Matrix effects and strategies for compensation.’ Mycotoxin Research 25: 201–213. doi: 10.1007/s12550-009-0029-8.
    • Fischbeck A, Krüger M, Blaas N, Humpf H. . ‘Analysis of sphingomyelin in meat based on hydrophilic interaction liquid chromatography coupled to electrospray lonization-tandem mass spectrometry (HILIC-HPLC-ESI-MS/MS).’ Journal of Agricultural and Food Chemistry 57: 9469–9474. doi: 10.1021/jf9025376.
    • Schwerdt G, Königs M, Holzinger H, Humpf H, Gekle M. . ‘Effects of the mycotoxin fumonisin B1 on cell death in human kidney cells and human lung fibroblasts in primary culture.’ Journal of Applied Toxicology 29: 174–182. doi: 10.1002/jat.1398.
    • Cramer B, Beyer M, Humpf H. . Stable isotope labeled mycotoxins as standards for HPLC-MS/MS analysis: Review and evaluation of published procedures for the introduction of stable isotopes into mycotoxins. Washington: American Chemical Society. doi: 10.1021/bk-2009-1031.ch018.

    • Danicke S, Beineke A, Goyarts T, Valenta H, Beyer M, Humpf HU. . ‘Effects of a Fusarium toxin-contaminated triticale, either untreated or treated with sodium metabisulphite (Na2S2O5, SBS), on weaned piglets with a special focus on liver function as determined by the C-13-methacetin breath test.’ Archives of Animal Nutrition 62, Nr. 4: 263–286. doi: 10.1080/17450390802214167.
    • Aldick T, Bielaszewska M, Uhlin BE, Humpf HU, Wai SN, Karch H. . ‘Enterohemorrhagic Escherichia coli hemolysin delivery to target cells.’ International Journal of Medical Microbiology 298: 84.
    • Cramer B, Konigs M, Humpf HU. . ‘Identification and in vitro cytotoxicity of ochratoxin a degradation products formed during coffee roasting.’ Journal of Agricultural and Food Chemistry 56, Nr. 14: 5673–5681. doi: 10.1021/jf801296z.
    • Trebstein A, Seefelder W, Lauber U, Humpf HU. . ‘Determination of T-2 and HT-2 toxins in cereals including oats after immunoaffinity cleanup by liquid chromatography and fluorescence detection.’ Journal of Agricultural and Food Chemistry 56, Nr. 13: 4968–4975. doi: 10.1021/jf800316m.
    • Konigs M, Schwerdt G, Gekle M, Humpf HU. . ‘Effects of the mycotoxin deoxynivalenol on human primary hepatocytes.’ Molecular Nutrition and Food Research 52, Nr. 7: 830–839. doi: 10.1002/mnfr.200700439.
    • Gong YY, Torres-Sanchez L, Lopez-Carrillo L, Peng JH, Sutcliffe AE, White KL, Humpf HU, Turner PC, Wild CP. . ‘Association between tortilla consumption and human urinary fumonisin B1 levels in a Mexican population.’ Cancer Epidemiology, Biomarkers and Prevention 17, Nr. 3: 688–694. doi: 10.1158/1055-9965.EPI-07-2534.
    • Hein EM, Rose K, Van't Slot G, Friedrich AW, Humpf HU. . ‘Deconjugation and degradation of flavonol glycosides by pig cecal microbiota characterized by fluorescence in situ hybridization (FISH).’ Journal of Agricultural and Food Chemistry 56, Nr. 6: 2281–2290. doi: 10.1021/jf073444o.
    • Goßmann M, Beran F, Bedlan G, Plenk A, Hamedinger S, Öhlinger R, Humpf H, Büttner C. . ‘Investigation on asparagus spears during the main harvest byFusarium spp.- infections and contamination by Fumonisin B1 | Spargelstangenuntersuchungen zur Haupterntezeit auf Infektionen mitFusarium spp. und Kontaminationen mit Fumonisin B1.’ Mycotoxin Research 24: 88–97. doi: 10.1007/BF02985286.

    • Brockmeyer J, Bielaszewska M, Fruth A, Bonn ML, Mellmann A, Humpf HU, Karch H. . ‘Subtypes of the plasmid-encoded serine protease EspP in Shiga toxin-producing Escherichia coli: distribution, secretion, and proteolytic activity.’ Applied and Environmental Microbiology 73, Nr. 20: 6351–6359. doi: 10.1128/AEM.00920-07.
    • Koenigs M, Lenczyk M, Schwerdt G, Holzinger H, Gekle M, Humpf HU. . ‘Cytotoxicity, metabolism and cellular uptake of the mycotoxin deoxynivalenol in human proximal tubule cells and lung fibroblasts in primary culture.’ Toxicology 240, Nr. 1-2: 48–59. doi: 10.1016/j.tox.2007.07.016.
    • Cramer B, Bretz M, Humpf HU. . ‘Stable isotope dilution analysis of the Fusarium mycotoxin zearalenone.’ Journal of Agricultural and Food Chemistry 55, Nr. 21: 8353–8358. doi: 10.1021/jf0717283.
    • Seiferlein M, Humpf HU, Voss KA, Sullards MC, Allegood JC, Wang E, Merrill AH. . ‘Hydrolyzed fumonisins HFB1 and HFB2 are acylated in vitro and in vivo by ceramide synthase to form cytotoxic N-acyl-metabolites.’ Molecular Nutrition and Food Research 51, Nr. 9: 1120–1130. doi: 10.1002/mnfr.200700118.
    • Schwerdt G, Holzinger H, Sauvant C, Konigs M, Humpf HU, Gekle M. . ‘Long-term effects of ochratoxin A on fibrosis and cell death in human proximal tubule or fibroblast cells in primary culture.’ Toxicology 232, Nr. 1-2: 57–67. doi: 10.1016/j.tox.2006.12.008.
    • Seiferlein M, Humpf H, Voss K, Sullards M, Allegood J, Wang E, Merrill Jr. A. . ‘Hydrolyzed fumonisins HFB1 and HFB2 are acylated in vitro and in vivo by ceramide synthase to form cytotoxic N-acyl-metabolites.’ Molecular Nutrition and Food Research 51: 1120–1130. doi: 10.1002/mnfr.200700118.

    • Bartke N, Fischbeck A, Humpf HU. . ‘Analysis of sphingolipids in potatoes (Solanum tuberosum L.) and sweet potatoes (Ipomoea batatas (L.) Lam.) by reversed phase high-performance liquid chromatography electrospray ionization tandem mass spectrometry (HPLC-ESI-MS/MS).’ Molecular Nutrition and Food Research 50, Nr. 12: 1201–1211. doi: 10.1002/mnfr.200600140.
    • Keppler K, Hein EM, Humpf HU. . ‘Metabolism of quercetin and rutin by the pig caecal microflora prepared by freeze-preservation.’ Molecular Nutrition and Food Research 50, Nr. 8: 686–695. doi: 10.1002/mnfr.200600016.
    • Bretz M, Beyer M, Cramer B, Knecht A, Humpf HU. . ‘Thermal degradation of the Fusarium mycotoxin deoxynivalenol.’ Journal of Agricultural and Food Chemistry 54, Nr. 17: 6445–6451. doi: 10.1021/jf061008g.
    • Knecht A, Humpf HU. . ‘Cytotoxic and antimitotic effects of N-containing Monascus metabolites studied using immortalized human kidney epithelial cells.’ Molecular Nutrition and Food Research 50, Nr. 4-5: 406–412. doi: 10.1002/mnfr.200500238.
    • Klotzel M, Lauber U, Humpf HU. . ‘A new solid phase extraction clean-up method for the determination of 12 type A and B trichothecenes in cereals and cereal-based food by LC-MS/MS.’ Molecular Nutrition and Food Research 50, Nr. 3: 261–269. doi: 10.1002/mnfr.200500234.
    • Knecht A, Cramer B, Humpf HU. . ‘New Monascus metabolites: Structure elucidation and toxicological properties studied with immortalized human kidney epithelial cells.’ Molecular Nutrition and Food Research 50, Nr. 3: 314–321. doi: 10.1002/mnfr.200500229.
    • Bretz M, Beyer M, Cramer B, Humpf HU. . ‘Stable isotope dilution analysis of the Fusarium mycotoxins deoxynivalenol and 3-acetyldeoxynivalenol.’ Molecular Nutrition and Food Research 50, Nr. 3: 251–260. doi: 10.1002/mnfr.200500230.
    • Labib S, Hummel S, Richling E, Humpf HU, Schreier P. . ‘Use of the pig caecum model to mimic the human intestinal metabolism of hispidulin and related compounds.’ Molecular Nutrition and Food Research 50, Nr. 1: 78–86. doi: 10.1002/mnfr.200500144.
    • Bartke N, Fischbeck A, Humpf H. . ‘Analysis of sphingolipids in potatoes (Solanum tuberosum L.) and sweet potatoes (Ipomoea batatas (L.) Lam.) by reversed phase high-performance liquid chromatography electrospray ionization tandem mass spectrometry (HPLC-ESI-MS/MS).’ Molecular Nutrition and Food Research 50: 1201–1211. doi: 10.1002/mnfr.200600140.

    • Bretz M, Beyer M, Cramer B, Humpf HU. . ‘Synthesis of stable isotope labeled 3-acetyldeoxynivalenol.’ Molecular Nutrition and Food Research 49, Nr. 12: 1151–1153. doi: 10.1002/mnfr.200500153.
    • Goßmann M, Kleta S, Humpf H-U, Büttner C. . ‘Investigation on contamination of asparagus spears (Asparagus officinalis L.) with Fusarium proliferatum (Matsushima) Nirenberg during main harvest | Untersuchungen zum endophytischen Befall von Fusarium proliferatum (Matsushima) Nirenberg in geernteten Stangen von Spargel (Asparagus officinalis L.).’ Gesunde Pflanzen 57, Nr. 2-3: 53–58. doi: 10.1007/s10343-005-0065-z.
    • Klotzel M, Gutsche B, Lauber U, Humpf HU. . ‘Determination of 12 type A and B trichothecenes in cereals by liquid chromatography-electrospray ionization tandem mass spectrometry.’ Journal of Agricultural and Food Chemistry 53, Nr. 23: 8904–8910. doi: 10.1021/jf051501c.
    • Keppler K, Humpf HU. . ‘Metabolism of anthocyanins and their phenolic degradation products by the intestinal microflora.’ Bioorganic and Medicinal Chemistry 13, Nr. 17: 5195–5205. doi: 10.1016/j.bmc.2005.05.003.
    • Klotzel M, Schmidt S, Lauber U, Thielert G, Humpf HU. . ‘Comparison of different clean-up procedures for the analysis of deoxynivalenol in cereal-based food and validation of a reliable HPLC method.’ Chromatographia 62, Nr. 1-2: 41–48. doi: 10.1365/s10337-005-0576-x.
    • Liu CL, Liu FM, Xu WN, Kofoet A, Humpf HU, Jiang SR. . ‘Occurrence of fumonisins B-1 and B-2 in asparagus from Shandong province, P.R. China.’ Food additives and contaminants 22, Nr. 7: 673–676. doi: 10.1080/02652030500133016.
    • Bretz M, Knecht A, Gockler S, Humpf HU. . ‘Structural elucidation and analysis of thermal degradation products of the Fusarium mycotoxin nivalenol.’ Molecular Nutrition and Food Research 49, Nr. 4: 309–316. doi: 10.1002/mnfr.200400092.
    • Fischbeck A, Bartke N, Humpf HU. . ‘New applications of the CD Exciton chirality method. Stereochemical assignment of organic compounds containing carboxylic acid groups.’ Chemical Monthly / Monatshefte für Chemie 136, Nr. 3: 397–410. doi: 10.1007/s00706-004-0277-4.
    • Bretz M, Göckler S, Humpf H. . ‘Isolation and structural elucidation of thermal degradation products of the Fusarium mycotoxin nivalenol.’ Mycotoxin Research 21: 15–17. doi: 10.1007/BF02954807.
    • Knecht A, Schwerdt G, Gekle M, Humpf H. . ‘Combinatory effects of citrinin and ochratoxin A in immortalized human proximal tubule cells.’ Mycotoxin Research 21: 176–181. doi: 10.1007/BF02959258.
    • Goßmann M, Kleta S, Humpf H, Büttner C. . ‘Investigation on contamination of asparagus spears (Asparagus officinalis L.) with Fusarium proliferatum (Matsushima) Nirenberg during main harvest | Untersuchungen zum endophytischen Befall von Fusarium proliferatum (Matsushima) Nirenberg in geernteten Stangen von Spargel (Asparagus officinalis L.).’ Gesunde Pflanzen 57: 53–58. doi: 10.1007/s10343-005-0065-z.
    • Bretz M, Göckler S, Humpf H. . ‘Isolation and structural elucidation of thermal degradation products of the Fusarium mycotoxin nivalenol | Isolierung und Strukturaufklärung von thermischen Abbauprodukten des Mykotoxins Nivalenol.’ Mycotoxin Research 21: 15–17. doi: 10.1007/BF02954807.

    • Humpf HU, Voss KA. . ‘Effects of thermal food processing on the chemical structure and toxicity of fumonisin mycotoxins.’ Molecular Nutrition and Food Research 48, Nr. 4: 255–269. doi: 10.1002/mnfr.200400033.
    • Royer D, Humpf HU, Guy PA. . ‘Quantitative analysis of Fusarium mycotoxins in maize using accelerated solvent extraction before liquid chromatography atmospheric pressure chemical ionization tandem mass spectrometry.’ Food additives and contaminants 21, Nr. 7: 678–692. doi: 10.1080/02652030410001711304.
    • Royer D, Humpf H, Guy P. . ‘Quantitative analysis of Fusarium mycotoxins in maize using accelerated solvent extraction before liquid chromatography/atmospheric pressure chemical ionization tandem mass spectrometry.’ Food additives and contaminants 21: 678–692. doi: 10.1080/02652030410001711304.

    • Seefelder W, Humpf HU, Schwerdt G, Freudinger R, Gekle M. . ‘Induction of apoptosis in cultured human proximal tubule cells by fumonisins and fumonisin metabolites.’ Toxicology and Applied Pharmacology 192, Nr. 2: 146–153. doi: 10.1016/S0041-008X(03)00262-X.
    • Seefelder W, Knecht A, Humpf HU. . ‘Bound fumonisin B-1: Analysis of fumonisin-B-1 glyco and amino acid conjugates by liquid chromatography-electrospray ionization-tandem mass spectrometry.’ Journal of Agricultural and Food Chemistry 51, Nr. 18: 5567–5573. doi: 10.1021/jf0344338.
    • Wild D, Toth G, Humpf HU. . ‘New Monascus metabolites with a pyridine structure in red fermented rice.’ Journal of Agricultural and Food Chemistry 51, Nr. 18: 5493–5496. doi: 10.1021/jf030213i.
    • Seefelder W, Knecht A, Humpf H. . ‘Bound fumonisin B1: Analysis of fumonisin-B1 glyco and amino acid conjugates by liquid chromatography-electrospray ionization-tandem mass spectrometry.’ Journal of Agricultural and Food Chemistry 51: 5567–5573. doi: 10.1021/jf0344338.

    • Desai K, Sullards MC, Allegood J, Wang E, Schmelz EM, Hartl M, Humpf HU, Liotta DC, Peng Q, Merrill AH. . ‘Fumonisins and fumonisin analogs as inhibitors of ceramide synthase and inducers of apoptosis.’ Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids 1585, Nr. 2-3: 188–192. doi: 10.1016/S1388-1981(02)00340-2.
    • Seefelder W, Schwerdt G, Freudinger R, Gekle M, Humpf HU. . ‘Liquid chromatography/electrospray ionisation-mass spectrometry method for the quantification of sphingosine and sphinganine in cell cultures exposed to fumonisins.’ Journal of Chromatography B 780, Nr. 1: 137–144. doi: 10.1016/S1570-0232(02)00440-3.
    • Wild D, Toth G, Humpf HU. . ‘New Monascus metabolite isolated from red yeast rice (angkak, red koji).’ Journal of Agricultural and Food Chemistry 50, Nr. 14: 3999–4002. doi: 10.1021/jf020023s.
    • Seefelder W, Gossmann M, Humpf HU. . ‘Analysis of fumonisin B-1 in Fusarium proliferatum-infected asparagus spears and garlic bulbs from Germany by liquid chromatography - Electrospray ionization mass spectrometry.’ Journal of Agricultural and Food Chemistry 50, Nr. 10: 2778–2781. doi: 10.1021/jf0115037.
    • Weil K, Humpf HU, Schwab W, Schreier P. . ‘Absolute configuration of 3-hydroxy acids formed by Stenotrophomonas maltophilia: Application of multidimensional gas chromatography and circular dichroism spectroscopy.’ Chirality 14, Nr. 1: 51–58. doi: 10.1002/chir.10029.
    • Merill AH, Sullards C, Allegood J, Wang E, Linn SC, Andras L, Liotta DC, Hartl M, Humpf HU. . ‘Insights into the Modulation of Ceramide Metabolism by Naturally Occurring and Synthetic Sphingolipid Analogs as Monitored by Electrospray Tandem Mass.’ In Ceramide Signaling, edited by Futerman AH, 1–8. New York: Springer International Publishing.
    • Wild D, Gareis M, Humpf H. . ‘Analyses of red fermented rice (angkak) and report of a new Monascus metabolite.’ Mycotoxin Research 18: 212–216. doi: 10.1007/BF02946098.
    • Seefelder W, Gossmann M, Humpf H. . ‘Analysis of Fumonisin B1 in Fusarium proliferatum-infected asparagus spears and garlic bulbs from Germany by liquid chromatography-electrospray ionization mass spectrometry.’ Journal of Agricultural and Food Chemistry 50: 2778–2781. doi: 10.1021/jf0115037.

    • Weckerle B, Schreier P, Humpf HU. . ‘A new one-step strategy for the stereochemical assignment of acyclic 2-and 3-sulfanyl-1-alkanols using the CD exciton chirality method.’ Journal of Organic Chemistry 66, Nr. 24: 8160–8164. doi: 10.1021/jo010768h.
    • Broring M, Brandt CD, Lex J, Humpf HU, Bley-Escrich J, Gisselbrecht JP. . ‘Molecular and electronic structure of (2,2 '-bidipyrrinato)nickel(II) complexes.’ European Journal of Inorganic Chemistry , Nr. 10: 2549–2556. doi: 10.1002/1099-0682(200109)2001:102549::AID-EJIC2549>3.0.CO;2-7.
    • Adam W, Humpf HU, Roschmann KJ, Saha-Moller CR. . ‘Enantioselective epoxidation with chiral Mn-III(salen) catalysts: Kinetic resolution of aryl-substituted allylic alcohols.’ Journal of Organic Chemistry 66, Nr. 17: 5796–5800. doi: 10.1021/jo010350j.
    • Hartl M, Humpf HU. . ‘Combined synthetic/CD strategy for the stereochemical assignment of the tricarballylic acid side chains of fumonisin B-1.’ Journal of Organic Chemistry 66, Nr. 11: 3678–3681. doi: 10.1021/jo0000630.
    • Seefelder W, Hartl M, Humpf HU. . ‘Determination of N-(carboxymethyl)fumonisin B-1 in corn products by liquid chromatography/electrospray ionization-mass spectrometry.’ Journal of Agricultural and Food Chemistry 49, Nr. 5: 2146–2151. doi: 10.1021/jf001429c.
    • Seefelder W, Humpf H. . ‘Formation of Fumonisin artefacts in thermal treated food.’ Mycotoxin Research 17: 116–119. doi: 10.1007/BF03036725.
    • Seefelder W, Humpf HU, Schwerdt G, Freudinger R, Gekle M. . ‘Induction of Apoptosis in Cultured Human Proximal Tubule Cells by Fumonisins and Fumonisin Metabolites.’ Mycotoxin Research 17A: 107–111. doi: 10.1016/S0041-008X(03)00262-X.
    • Seefelder W, Hartl M, Humpf H. . ‘Determination of N-(carboxymethyl)fumonisin B1 in corn products by liquid chromatography/electrospray ionization-mass spectrometry.’ Journal of Agricultural and Food Chemistry 49: 2146–2151. doi: 10.1021/jf001429c.
    • Adam W, Humpf H, Roschmann K, Saha-Möller C. . ‘Enantioselective epoxidation with chiral MnIII(salen) catalysts: Kinetic resolution of aryl-substituted allylic alcohols.’ Journal of Organic Chemistry 66: 5796–5800. doi: 10.1021/jo010350j.
    • Bröring M, Brandt C, Lex J, Humpf H, Bley-Escrich J, Gisselbrecht J. . ‘Molecular and electronic structure of (2,2′-bidipyrrinato)nickel(II) complexes.’ European Journal of Inorganic Chemistry 10: 2549–2556. doi: 10.1002/1099-0682(200109)2001:10<2549::AID-EJIC2549>3.0.CO;2-7.

    • Hartl M, Humpf HU. . ‘Toxicity assessment of fumonisins using the brine shrimp (Artemia salina) bioassay.’ Food and Chemical Toxicology 38, Nr. 12: 1097–1102. doi: 10.1016/S0278-6915(00)00112-5.
    • Adam W, Groer P, Humpf HU, Saha-Moller CR. . ‘Synthesis of optically active alpha-methylene beta-lactams through lipase-catalyzed kinetic resolution.’ Journal of Organic Chemistry 65, Nr. 16: 4919–4922. doi: 10.1021/jo0003089.
    • Hartl M, Humpf HU. . ‘2-Naphthol as a powerful chromophore for the configurational assignment of carboxylic acid groups via the CD exciton chirality method.’ Tetrahedron: Asymmetry 11, Nr. 8: 1741–1747. doi: 10.1016/S0957-4166(00)00116-6.
    • Adam W, Lukacs Z, Viebach K, Humpf HU, Saha-Moller CR, Schreier P. . ‘Microscale determination of the absolute configuration of alpha-aryl-substituted alcohols by the CD exciton chirality method.’ Journal of Organic Chemistry 65, Nr. 1: 186–190. doi: 10.1021/jo991424i.
    • Hartl M, Humpf H. . ‘The brine shrimp (Artemia salina) bioassay: A simple method to assess the toxicity of fumonisin mycotoxins.’ Mycotoxin Research 16: 83. doi: 10.1007/BF02942988.
    • Adam W, Lukacs Z, Viebach K, Humpf H, Saha-Möller C, Schreier P. . ‘Microscale determination of the absolute configuration of α-aryl- substituted alcohols by the CD exciton chirality method.’ Journal of Organic Chemistry 65: 186–190. doi: 10.1021/jo991424i.
    • Adam W, Groer P, Humpf H, Saha-Möller C. . ‘Synthesis of optically active α-methylene β-lactams through lipase-catalyzed kinetic resolution.’ Journal of Organic Chemistry 65: 4919–4922. doi: 10.1021/jo0003089.

    • Hartl M, Herderich M, Humpf HU. . ‘Rapid determination of fumonisin FB1 in corn products by high-performance liquid chromatography-electrospray mass spectrometry.’ European Food Research and Technology 209, Nr. 5: 348–351. doi: 10.1007/s002170050507.
    • Hartl M, Humpf HU. . ‘Simultaneous determination of fumonisin B-1 and hydrolyzed fumonisin B-1 in corn products by liquid chromatography/electrospray ionization mass spectrometry.’ Journal of Agricultural and Food Chemistry 47, Nr. 12: 5078–5083. doi: 10.1021/jf990046f.
    • Degelmann P, Becker M, Herderich M, Humpf H-U. . ‘Determination of ochratoxin A in beer by high-performance liquid chromatography.’ Chromatographia 49, Nr. 9-10: 543–546. doi: 10.1007/BF02467756.
    • Hartl M, Herderich M, Humpf H. . ‘Rapid determination of fumonisin FB1 in corn products by high-performance liquid chromatography-electrospray mass spectrometry.’ European Food Research and Technology 209: 348–351. doi: 10.1007/s002170050507.
    • Hartl M, Humpf H. . ‘Simultaneous determination of fumonisin B1 and hydrolyzed fumonisin B1 in corn products by liquid chromatography/electrospray ionization mass spectrometry.’ Journal of Agricultural and Food Chemistry 47: 5078–5083. doi: 10.1021/jf990046f.

    • Hör K, Gimple O, Schreier P, Humpf H-U. . ‘Absolute Configurational Assignment of Acyclic Hydroxy Carboxylic Acids: A New Strategy in Exciton-Coupled Circular Dichroism.’ Journal of Organic Chemistry 63, Nr. 2: 322–325.
    • Hartl M, Humpf H-U. . ‘Assigning the absolute configuration of fumonisins by the circular dichroism exciton chirality method.’ Tetrahedron: Asymmetry 9, Nr. 9: 1549–1556. doi: 10.1016/S0957-4166(98)00123-2.
    • Roth M, Gutsche B, Herderich M, Humpf H-U, Schreier P. . ‘Dioxygenation of Long-Chain Alkadien(trien)ylphenols by Soybean Lipoxygenase.’ Journal of Agricultural and Food Chemistry 46, Nr. 8: 2951–2956. doi: 10.1021/jf980196a.
    • Adam W, Lazarus M, Schmerder A, Humpf H-U, Saha-Möller CR, Schreier P. . ‘Synthesis of optically active α-hydroxy acids by kinetic resolution through lipase-catalyzed enantioselective acetylation.’ European Journal of Organic Chemistry , Nr. 9: 2013–2018. doi: 10.1002/(SICI)1099-0690(199809)1998:92013::AID-EJOC2013>3.0.CO;2-S.
    • Adam W, Boland W, Hartmann-Schreier J, Humpf H-U, Lazarus M, Saffert A, Saha-Möller CR, Schreier P. . ‘α hydroxylation of carboxylic acids with molecular oxygen catalyzed by the α oxidase of peas (Pisum sativum): A novel biocatalytic synthesis of enantiomerically pure (R)-2-hydroxy acids.’ Journal of the American Chemical Society 120, Nr. 43: 11044–11048. doi: 10.1021/ja981252r.
    • Humpf HU, Schmelz EM, Meredith FI, Vesper H, Vales TR, Wang E, Menaldino DS, Liotta DC, Merrill AH. . ‘Acylation of naturally occurring and synthetic 1-deoxysphinganines by ceramide synthase. Formation of N-palmitoyl-aminopentol produces a toxic metabolite of hydrolyzed fumonisin, AP1, and a new category of ceramide synthase inhibitor.Journal of Biological Chemistry 273, Nr. 30: 19060–19064. doi: 10.1074/jbc.273.30.19060.
    • Humpf H-U. . ‘Fumonisine in Lebensmitteln: Empfindlicher und selektiver Nachweis mittels HPLC-MS/MS.GIT 42, Nr. 2: 84–85.
    • Becker M, Degelmann P, Herderich M, Schreier P, Humpf HU. . ‘High-Performance Liquid Chromatography-Electrospray Ionisation-Tandem Mass Spectrometry (HPLC-ESI-MS/MS) for the Analysis of Ochratoxin.’ J. Chromatogr. 818, Nr. 2: 260–264.
    • Humpf HU, Schmelz EM, Meredith FI, Merrill AH. . ‘N-Palmitoyl-HFB1: A New Metabolite of Hydrolyzed Fumonisin (HFB1) in Rat Liver Microsomes.’ Rev. Méd. Vét 149, Nr. 6: 576.
    • Humpf H, Schmelz E, Meredith F, Vesper H, Vales T, Wang E, Menaldino D, Liotta D, Merrill Jr. A. . ‘Acylation of naturally occurring and synthetic 1-deoxysphinganines by ceramide synthase: Formation of N-palmitoyl-aminopentol produces a toxic metabolite of hydrolyzed fumonisin, AP1, and a new category of ceramide synthase inhibitor.’ Journal of Biological Chemistry 273: 19060–19064. doi: 10.1074/jbc.273.30.19060.
    • Becker M, Degelmann P, Herderich M, Schreier P, Humpf H. . ‘Column liquid chromatography-electrospray ionisation-tandem mass spectrometry for the analysis of ochratoxin.’ Journal of Chromatography A 818: 260–264. doi: 10.1016/S0021-9673(98)00594-9.

    • Gimple O, Schreier P, Humpf H-U. . ‘A new exciton-coupled circular dichroism method for assigning the absolute configuration in acyclic α- and β-hydroxy carboxylic acids.’ Tetrahedron: Asymmetry 8, Nr. 1: 11–14. doi: 10.1016/S0957-4166(96)00490-9.
    • Herderich M, Richling E, Röscher R, Schneider C, Schwab W, Humpf H-U, Schreier P. . ‘Application of atmospheric pressure ionization HPLC-MS-MS for the analysis of natural products.’ Chromatographia 45: 127–132. doi: 10.1007/BF02505549.
    • Hoch U, Humpf H-U, Schreier P, Saha-Möller CR, Adam W. . ‘Configurational assignment of optically active hydroperoxy homoallylic alcohols and the corresponding diols by circular dichroism and multidimensional gas chromatography.’ Chirality 9, Nr. 1: 69–74. doi: 10.1002/(SICI)1520-636X(1997)9:169::AID-CHIR13>3.3.CO;2-W.
    • Adam W, Lazarus M, Boss B, Saha-Möller CR, Humpf H-U, Schreier P. . ‘Enzymatic Resolution of Chiral 2-Hydroxy Carboxylic Acids by Enantioselective Oxidation with Molecular Oxygen Catalyzed by the Glycolate Oxidase from Spinach (Spinacia oleracea).’ Journal of Organic Chemistry 62, Nr. 22: 7844–7849.
    • Schneider C, Schreier P, Humpf H-U. . ‘Exciton-coupled circular dichroism (ECCD) in acyclic hydroxylated dienes: A sensitive method for the direct stereochemical assignment of lipoxygenase products.’ Chirality 9, Nr. 5-6: 563–567. doi: 10.1002/(SICI)1520-636X(1997)9:5/6563::AID-CHIR25>3.3.CO;2-5.
    • Adam W, Humpf H-U, Korb MN, Schreier P. . ‘The configurational assignment of the optically active 5-(1-hydro- peroxyethyl)-3-ethoxycarbonyl-2-methylfuran and its alcohol by exciton- coupled circular dichroism (ECCD).’ Tetrahedron: Asymmetry 8, Nr. 21: 3555–3558. doi: 10.1016/S0957-4166(97)00515-6.

    • Schreder B, Lukacs Z, Schmitt M, Schreier P, Humpf H-U. . ‘1-Naphthoic acid: A new type of asymmetric chromophore for exciton-coupled circular dichroism (ECCD).’ Tetrahedron: Asymmetry 7, Nr. 6: 1543–1546. doi: 10.1016/0957-4166(96)00176-0.
    • Adam W, Hoch U, Humpf H-U, Saha-Möller CR, Schreier P. . ‘Horseradish peroxidase (HRP)-catalysed enantioselective reduction of racemic hydroperoxy homoallylic alcohols: A novel enzymatic method for the preparation of optically active, unsaturated diols and hydroperoxy alcohols.’ Chemical communications , Nr. 24: 2701–2702. doi: 10.1039/cc9960002701.
    • Lukacs Z, Schaper S, Herderich M, Schreier P, Humpf H-U. . ‘Identification and determination of fumonisin FB1 and FB2 in corn and corn products by high-performance liquid chromatography - Electrospray-ionization tandem mass spectrometry (HPLC-ESI-MS-MS).’ Chromatographia 43, Nr. 3-4: 124–128. doi: 10.1007/BF02292939.
    • Lukacs Z, Schaper S, Herderich M, Schreier P, Humpf H. . ‘Identification and determination of fumonisin FB1 and FB2 in corn and corn products by high-performance liquid chromatography - Electrospray-ionization tandem mass spectrometry (HPLC-ESI-MS-MS).’ Chromatographia 43: 124–128. doi: 10.1007/BF02292939.

    • Person RV, Monde K, Humpf HU, Berova N, Nakanishi K. . ‘A new approach in exciton-coupled circular dichroism (ECCD)--insertion of an auxiliary stereogenic center.Chirality 7, Nr. 3: 128. doi: 10.1002/chir.530070304.
    • Humpf H-U, Berova N, Nakanishi K, Jarstfer MB, Poulter CD. . ‘Allylic and homoallylic exciton coupled CD: A sensitive method for determining the absolute stereochemistry of natural products.’ Journal of Organic Chemistry 60, Nr. 11: 3539–3542. doi: 10.1021/jo00116a048.
    • Person R, Monde K, Humpf H, Berova N, Nakanishi K. . ‘A new approach in exciton‐coupled circular dichroism (ECCD)—insertion of an auxiliary stereogenic center.’ Chirality 7: 128–135. doi: 10.1002/chir.530070304.

    • Humpf HU, Zhao N, Berova N, Nakanishi K, Schreier P. . ‘Absolute stereochemistry of natural 3,4-dihydroxy-beta-ionone glycosides by the CD exciton chirality method.Journal of Natural Products 57, Nr. 12: 1762–1765. doi: 10.1021/np50114a027.
    • Humpf H, Zhao N, Berova N, Nakanishi K, Schreier P. . ‘Absolute stereochemistry of natural 3,4-Dihydroxy-β-ionone glycosides by the cd exciton chirality method.’ Journal of Natural Products 57: 1762–1765. doi: 10.1021/np50114a027.

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