Welcome to the Collaborative Research Center 1348

The precise spatial and temporal organization of cellular differentiation, essential for organismal development and physiology, depends on the correct formation and function of cellular interfaces. These interfaces facilitate the efficient transfer of materials and information between cells, through the dynamic assembly of molecular platforms at the plasma membrane. Such platforms integrate external and internal signals and transduce mechanical forces, guiding development and ensuring correct responses to physiological and pathophysiological changes. The Collaborative Research Center (CRC) 1348 focuses on understanding how these dynamic cellular interfaces are formed and how they control decision-making in cells and tissues.

We have developed a comprehensive strategy combining molecular modeling, structural biology, biochemistry, organic synthesis, genetics, cellular and developmental biology. This approach aims to unravel the molecular mechanisms governing cellular interactions and responses in individual cells as well as in multicellular organisms. Leveraging advances in high-resolution imaging, optogenetics, single-cell technologies, synthetic biology, and engineering, CRC 1348 aims to not only understand but also to precisely manipulate dynamic processes at the plasma membrane. Our goal is to provide a deep understanding of the molecular principles that govern cellular interface formation and function, setting the foundation for future efforts to recreate biological complexity from the bottom up.

IRTG 1348 Alumni Talks

21.10.25 with Dr. Till Matzat & 18.11.25 with Dr. Manuel Hollmann
© Uni Münster

Join us for two inspiring sessions with IRTG 1348 alumni sharing their career journeys beyond the PhD!

  • October 21, 2025
    Dr. Till Matzat, PlasmidSaurus, Cologne
  • November 18, 2025
    Dr. Manuel Hollmann, Helios Clinics, Berlin

They will discuss “What do I do now, how did I get there, and how does it maybe relate to what I did during my PhD?” — offering personal insights and practical advice for current PhD students.

Do not miss the chance to learn from their experiences and ask your questions!

SFB 1348 Seminar

October 23, 2025
© Uni Münster

Exciting seminar with Alex Gould about "Nutritional stress and neural stem cells".
Click here for more information.

"Ordnung aus Chaos - das Innenleben einer Zelle"

Vortrag für Lehrkräfte und Schüler*innen am 10.11.25 mit Prof. Dr. Wedlich-Söldner
© Raphael Schleutker

Wie auf einer Großbaustelle läuft auch in der Zelle alles nach einem präzisen Plan ab – nur im Mikroskop erkennbar. Am Institut für Zelldynamik und Bildgebung steht dabei das Zytoskelett im Mittelpunkt: Es gibt der Zelle Form, Stabilität und ermöglicht den Transport von Molekülen. Der Vortrag zeigt, wie interdisziplinäre Forschung diese dynamischen Prozesse sichtbar und verstehbar macht.

Weitere Informationen & Anmeldung

How to get to the CRC 1348?

© Uni Münster/Michael Kuhlmann

The CRC 1348 office is located in the Multiscale Imaging Center (MIC). Our seminars take place in the MIC auditorium.

  • Arrival by public transport

    From Münster central station (Münster Westf Hbf) you can reach the MIC by bus in around 30 minutes.

    Bus stops:

    • Schreiberstraße: bus line 5, every 15 minutes from Münster Westf Hbf/bus platform B1 – bus line 11, every 20 minutes from Münster Westf Hbf/bus platform C1
    • Mendelstraße: bus line 2, every 30 minutes from Münster Westf Hbf/bus platform C1
    • P + R Coesfelder Kreuz: bus line 12, every 20 minutes from Münster Westf Hbf/bus platform C1

    (Status as of November 2023)

  • Arrival by plane

    • Airport Düsseldorf (DUS): Several train connections to Münster central station (Münster Westf Hbf), travel time approximately 1,5 hours
    • Airport Münster-Osnabrück (FMO): Small airport, bus connection to Münster central station (Münster Westf Hbf), bus line S50, leaving every 60 minutes, travel time approximately 30 minutes

    (Status as of November 2023)