CV
Academic Education
- PhD in biophysical chemistry, Bielefeld University
- Master of Science in physical chemistry, University of Bielefeld
- Bachelor of Science in biochemistry, University of Bielefeld
Positions
- akademische Rätin, Arbeitskreis Prof. Braunschweig, Physikalische Chemie, WWU Münster
- akademische Rätin, Physical chemistry, WWU Münster
- research fellow, Biophysical chemistry, University of Bielefeld
Honors
- Posterpreis – European Colloid and Interface Society (ECIS)
- Förderpreis der Friedrich-Wilhelm-Helweg-Stiftung – Fakultät für Biologie der Universität Bielefeld
Research Articles (Journals)
- Hägerbäumer, Pia, Dargel, Carina, Gräbitz-Bräuer, Friederike, Hoffmann, Ingo, Mix, Andreas, Förster, Beate, Sabadasch, Viktor, Schweins, Ralf, and Hellweg, Thomas. . “Characterization of cholesterol-containing DOPG bilayers in the presence of the saponins aescin and glycyrrhizin: A NMR and scattering study.” Colloids and Surfaces B: Biointerfaces 258 115226. doi: 10.1016/j.colsurfb.2025.115226.
- Moleiro, Lara H., Herráez-Aguilar, Diego, Solís-Fernández, Guillermo, Caselli, Niccolo, Dargel, Carina, Dodero, Verónica I., Bautista, José M., Hellweg, Thomas, and Monroy, Francisco. . “Mechanical adaptivity of red blood cell flickering to extrinsic membrane stiffening by the solid-like biosurfactant β-Aescin.” Biophysical Journal 124 (9): 1478–1495. doi: 10.1016/j.bpj.2025.03.027.
- Azhdari, Suna, Linders, Jürgen, Coban, Deniz: Stank Tim Julian, Dargel, Carina, Gojzewski, Hubert, Hellweg, Thomas, Gröschel, Andre H., and Wurm, Frederik R. . “Fully Degradable Polyphosphoester Cubosomes for Sustainable Agrochemical Delivery.” Advanced Materials 2406831. doi: 10.1002/adma.202406831.
- Escobedo, Fatima, Gospalswamy, Mohanraj, Hägerbäumer, Pia, Stank, Tim Julian, Victor, Julian, Groth, Georg, Gohlke, Holger, Dargel, Carina, Hellweg, Thomas, and Etzkorn, Manuel. . “Characterization of size-tuneable aescin-lipid nanoparticles as platform for stabilization of membrane proteins.” Colloids and Surfaces B: Biointerfaces 242 114071. doi: 10.1016/j.colsurfb.2024.114071.
- Dargel, Carina, Moleiro, Lara H., Radulescu, Aurel, Stank, Tim Julian, and Hellweg, Thomas. . “Decomposition of mixed DMPC-aescin vesicles to bicelles is linked to the lipid's main phase transition: A direct evidence by using chain-deuterated lipid.” Journal of Colloid and Interface Science 679: 209–220. doi: 10.1016/j.jcis.2024.10.074.
- Graebitz-Braeuer, Friederike, Dargel, Carina, Geisler, Ramsia, Fandrich, Pascal, Sabadasch, Viktor, Porcar, Lionel, Mix, Andreas, and Hellweg, Thomas. . “Coexistence of DOPG model membranes and β-aescin micelles: a combined scattering and NMR study.” Colloid and Polymer Science 301: 1499–1512. doi: 10.1007/s00396-023-05168-0.
- Moleiro, Lara H., Martín-Romero, María T., Herráez-Aguilar, Diego, Santiago, José A., Niccolò, Caselli, Dargel, Carina, Geisler, Ramsia, and Hellweg, Thomas and Monroy Francisco. . “Dual mechanical impact of β-escin on model lipid membranes.” Frontiers in Soft Matter 3 1240878. doi: 10.3389/frsfm.2023.1240878.
- Haegerbaeumer, Pia, Graebitz-Braeuer, Friederike, Annegarn, Marco, Dargel, Carina, Stank, Tim Julian, Bizien, Thomas, and Hellweg, Thomas. . “Interactions between DMPC Model Membranes, the Drug Naproxen, and the Saponin β-Aescin.” Pharmaceutics 15 (2). doi: 10.3390/pharmaceutics15020379.
- Dargel, Carina, Graebitz-Braeuer, Friederike, Geisler, Ramsia, Fandrich, Pascal, Hannappel, Yvonne, Porcar, Lionel, and Hellweg, Thomas. . “Stable DOPG/Glycyrrhizin Vesicles with a Wide Range of Mixing Ratios: Structure and Stability as Seen by Scattering Experiments and Cryo-TEM.” Molecules 26 (16). doi: 10.3390/molecules26164959.
- Abitaev, Karina, Qawasmi, Yaseen, Atanasova, Petia, Dargel, Carina, Bill, Joachim, Hellweg, Thomas, and Sottmann, Thomas. . “Adjustable polystyrene nanoparticle templates for the production of mesoporous foams and ZnO inverse opals.” Colloid and Polymer Science 299 (2). doi: 10.1007/s00396-020-04791-5.
- Dieterich, Sonja, Prevost, Sylvain, Dargel, Carina, Sottmann, Thomas, and Giesselmann, Frank. . “Synergistic structures in lyotropic lamellar gels.” Soft Matter 16 (45). doi: 10.1039/d0sm01473g.
- Dargel, Carina, Hannappel, Yvonne, and Hellweg, Thomas. . “Heating-Induced DMPC/Glycyrrhizin Bicelle-to-Vesicle Transition: A X-Ray Contrast Variation Study.” Biophysical Journal 118 (10). doi: 10.1016/j.bpj.2020.03.022.
- Dirksen, Maxim, Dargel, Carina, Meier, Lukas, Brandel, Timo, and Hellweg, Thomas. . “Smart microgels as drug delivery vehicles for the natural drug aescin: uptake, release and interactions.” Colloid and Polymer Science 298 (6). doi: 10.1007/s00396-020-04632-5.
- Geisler, Ramsia, Dargel, Carina, and Hellweg, Thomas. . “The Biosurfactant β-Aescin: A Review on the Physico-Chemical Properties and Its Interaction with Lipid Model Membranes and Langmuir Monolayers.” Molecules 25 (1). doi: 10.3390/molecules25010117.
- Dargel, Carina, Geisler, Ramsia, Hannappel, Yvonne, Kemker, Isabell, Sewald, Norbert, and Hellweg, Thomas. . “Self-Assembly of the Bio-Surfactant Aescin in Solution: A Small-Angle X-ray Scattering and Fluorescence Study.” Colloids and Interfaces 3 (2). doi: 10.3390/colloids3020047.
- Sreij, Ramsia, Dargel, Carina, Schweins, Ralf, Prevost, Sylvain, Dattani, Rajeev, and Hellweg, Thomas. . “Aescin-Cholesterol Complexes in DMPC Model Membranes: A DSC and Temperature-Dependent Scattering Study.” Scientific Reports 9. doi: 10.1038/s41598-019-41865-z.
- Sreij, Ramsia, Dargel, Carina, Hannappel, Yvonne, Jestin, Jacques, Prevost, Sylvain, Dattani, Rajeev, Wrede, Oliver, and Hellweg, Thomas. . “Temperature dependent self-organization of DMPC membranes promoted by intermediate amounts of the saponin aescin.” BBA - Biomembranes 1861 (5). doi: 10.1016/j.bbamem.2019.01.015.
- Sreij, Ramsia, Prevost, Sylvain, Dargel, Carina, Dattani, Rajeev, Hertle, Yvonne, Wrede, Oliver, and Hellweg, Thomas. . “Interaction of the Saponin Aescin with Ibuprofen in DMPC Model Membranes.” Molecular pharmaceutics 15 (10). doi: 10.1021/acs.molpharmaceut.8b00421.
- Sreij, Ramsia, Dargel, Carina, Geisler, Philippe, Hertle, Yvonne, Radulescu, Aurel, Pasini, Stefano, Perez, Javier, Moleiro, Lara H., and Hellweg, Thomas. . “DMPC vesicle structure and dynamics in the presence of low amounts of the saponin aescin.” Physical Chemistry Chemical Physics 20 (14). doi: 10.1039/c7cp08027a.
- Sreij, Ramsia, Dargel, Carina, Moleiro, Lara H., Monroy, Francisco, and Hellweg, Thomas. . “Aescin Incorporation and Nanodomain Formation in DMPC Model Membranes.” Langmuir 33 (43). doi: 10.1021/acs.langmuir.7b02933.