Dr. Carina Dargel
© C. Dargel
Dr. Carina Dargel
Senior Lecturer
Institute for Physical Chemistry
Room E110
Corrensstr. 30
48149 Muenster
T: 0251 83 23426
cdargel@uni-muenster.de

  • CV

    Education

    PhD in biophysical chemistry, Bielefeld University
    Master of Science in physical chemistry, University of Bielefeld
    Bachelor of Science in biochemistry, University of Bielefeld

    Positions

    akademische Rätin, Arbeitskreis Prof. Braunschweig, Physikalische Chemie, WWU Münster
    akademische Rätin, Physical chemistry, WWU Münster
    research fellow, Biophysical chemistry, University of Bielefeld

    Honors

    Posterpreis – European Colloid and Interface Society (ECIS)
    Förderpreis der Friedrich-Wilhelm-Helweg-Stiftung – Fakultät für Biologie der Universität Bielefeld

  • Publications

    • Hägerbäumer, P; Gräbitz-Bräuer, F; Annegarn, M; Dargel, C; Stank, TJ; Bizien, T; Hellweg, T . . ‘Interactions between DMPC Model Membranes, the Drug Naproxen, and the Saponin β-Aescin .’ Pharmaceutics 15, No. 2: 379. doi: https://doi.org/10.3390/pharmaceutics15020379.
    • Moleiro, Lara H.; Martín-Romero, María T.; Herráez-Aguilar, Diego; Santiago, José A.; Niccolò, Caselli; Dargel, Carina; Geisler, Ramsia; Hellweg, Thomas and Monroy, Francisco. . ‘Dual mechanical impact of β-escin on model lipid membranes.’ Frontiers in Soft Matter 3: 1240878. doi: 10.3389/frsfm.2023.1240878.
    • Gräbitz-Bräuer*, F; Dargel*, C; Geisler, R; Fandrich, P; Sabadasch, V; Porcar, L; Mix, A; Hellweg, T. . ‘Coexistence of DOPG model membranes and β-aescin micelles: a combined scattering and NMR study.’ Colloid and Polymer Science 301. doi: 10.1007/s00396-023-05168-0.
    • Dargel C, Gräbitz-Bräuer F, Geisler R, Fandrich P, Hannappel Y, Porcar L, Hellweg T. . ‘Stable DOPG/Glycyrrhizin Vesicles with a Wide Range of Mixing Ratios: Structure and Stability as Seen by Scattering Experiments and Cryo-TEM.’ Molecules 26, No. 16: 4959. doi: 10.3390/molecules26164959.
    • Abitaev K, Qawasmi Y, Atanasova P, Dargel C, Bill J, Hellweg T, Sottmann T. . ‘Adjustable polystyrene nanoparticle templates for the production of mesoporous foams and ZnO inverse opals.’ Colloid and Polymer Science 299, No. 2: 243–258. doi: 10.1007/s00396-020-04791-5.
    • Dieterich S, Prèvost S, Dargel C, Sottmann T, Giesselmann F. . ‘Synergistic structures in lyotropic lamellar gels.’ Soft Matter 16, No. 45: 10268–10279. doi: 10.1039/D0SM01473G.
    • Geisler R, Dargel C, Hellweg T. . ‘The biosurfactant beta-aescin: a review on the physico-chemical properties and its interaction with lipid model membranes and Langmuir monolayers.’ Molecules 25, No. 1: 117. doi: 10.3390/molecules25010117.
    • Dirksen M, Dargel C, Meier L, Brändel T, Hellweg T. . ‘Smart microgels as drug delivery vehicles for the natural drug aescin: Uptake, release and interactions.’ Colloid and Polymer Science 298: 505–518. doi: 10.1007/s00396-020-04632-5.
    • Dargel C, Hannappel Y, Hellweg T. . ‘Heating-Induced DMPC/Glycyrrhizin Bicelle-to-Vesicle Transition: A X-Ray Contrast Variation Study.’ Biophysical Journal 118, No. 10: 2411–2425. doi: 10.1016/j.bpj.2020.03.022.
    • Sreij R, Dargel C, Hannappel Y, Jestin J, Prèvost S, Dattani R, Wrede O, Hellweg T. . ‘Temperature dependent self-organization of DMPC membranes promoted by intermediate amounts of the saponin aescin.’ Biochimica et Biophysica Acta (BBA)-Biomembranes 1861, No. 5: 897–906. doi: 10.1016/j.bbamem.2019.01.015.
    • Sreij R, Dargel C, Schweins R, Prèvost S,Dattani R, Hellweg T. . ‘Aescin-cholesterol complexes in DMPC model membranes: a DSC and temperature-dependent scattering study.’ Scientific Reports 9, No. 1: 1–15. doi: 10.1038/s41598-019-41865-z.
    • Dargel* C, Geisler* R, Hannappel Y, Kemker I, Sewald N, Hellweg T. . ‘Self-assembly of the bio-surfactant aescin in solution: A small-angle X-ray scattering and Fluorescence study.’ Colloids and Interfaces 3, No. 2: 47. doi: 10.3390/colloids3020047.
    • Sreij R, Dargel C, Geisler, P, Hertle Y, Radulescu A, Pasini S, Perez J, Moleiro LH, Hellweg T. . ‘DMPC vesicle structure and dynamics in the presence of low amounts of the saponin aescin.’ Physical Chemistry Chemical Physics 20, No. 14: 9070–9083. doi: 10.1039/C7CP08027A.
    • Sreij R, Prévost S, Dargel C, Dattani R, Hertle Y, Wrede O, Hellweg T. . ‘Interaction of the saponin aescin with ibuprofen in DMPC model membranes.’ Molecular pharmaceutics 15, No. 10: 4446–4461. doi: 10.1021/acs.molpharmaceut.8b00421.
    • Sreij R, Dargel C, Moleiro, LH, Monroy, F, Hellweg, T. . ‘Aescin incorporation and nanodomain formation in DMPC model membranes.’ Langmuir 33, No. 43: 12351–12361. doi: 10.1021/acs.langmuir.7b02933.