Die klinische Reviews-Datenbank UpToDate wurde aktualisiert und steht nun in der Version 15.2 zur Verfügung. Der UpToDate Newsletter enthält Informationen über die neuesten Änderungen, wie z.B. die Einführung einer neuen Suchmaschine, die mehrere Begriffe gleichzeitig suchen kann, wie z.B. ganze Sätze oder Fragen.

UpToDate performs a continuous review of over 375 journals and other resources. Updates are added as important new information is published. The literature review for version 15.3 is current through August 2007; this topic was last changed on September 21, 2007. The next version of UpToDate (16.1) will be released in March 2008.

Unter What’s New können Sie sich die veränderten Inhalte anzeigen lassen. In der Oncology sind dies z.B.:

BRAIN TUMORS
– Pseudoprogression after treatment of malignant gliomas
BREAST CANCER
– Cardiotoxicity and adjuvant trastuzumab
– Trastuzumab and HER-2-negative tumors
– Raloxifene and breast cancer chemoprevention
CHEMOTHERAPEUTIC AGENTS
– Calcium and magnesium salts to prevent oxaliplatin neurotoxicity
– Infusion durations for rituximab and bevacizumab
ENDOCRINE TUMORS
– Adjuvant mitotane and resected adrenocortical cancer
– Tyrosine kinase inhibitors for advanced thyroid cancer
GASTROINTESTINAL CANCER
– Sorafenib for advanced hepatocellular cancer
– Initial chemotherapy for metastatic colorectal cancer
– Perioperative FOLFOX for potentially resectable colorectal cancer liver metastases
– Induction chemotherapy versus chemoradiotherapy in gastroesophageal (GE) junction adenocarcinoma
GENERAL ONCOLOGIC ISSUES
– Effects of diet on cancer treatment outcome
– Tetracycline for the rash from EGF pathway blockade
– Prophylactic dalteparin in patients with malignant gliomas
– Pyridoxine ineffective in preventing acral erythema
– Dexrazoxane approved for anthracycline extravasation