Single Molecule Biology

Author(s): Alex E. Knight
ISBN: 978-0-12-374227-8
Elsevier 2009

Single molecule techniques, including single molecule fluorescence, optical tweezers, and scanning probe microscopy, allow for the manipulation and measurement of single biological molecules within a live cell or in culture. These approaches, amongst the most exciting tools available in biology today, offer powerful new ways to elucidate biological function, both in terms of revealing mechanisms of action on a molecular level as well as tracking the behaviour of molecules in living cells. This book provides the first complete and authoritative treatment of this rapidly emerging field, explicitly from a biological perspective. The contents of Single Molecule Biology are organized by biological system or molecule. Each chapter discusses insights that have been revealed about their mechanism, structure or function by single molecule techniques. Among the topics covered are enzymes, motor proteins, membrane channels, DNA, ribozymes, cytoskeletal proteins, and other key molecules of current interest. An introduction by the editor provides a concise review of key principles and an historical overview. The last section discusses applications in molecular diagnostics and drug discovery.

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Das obige Buch gehört zu den gut 1.000 dauerhaft von der ZB Med gekauften Online-Büchern des Elsevier-Verlags der Jahre 1995-2008 und 2009, die in den folgenden Sachgebieten erschienen sind: Biochemistry, Genetics and Molecular Biology; Forensics; Immunology and Microbiology; Medicine and Dentistry; Neuroscience; Pharmacology, Toxicology and Pharmaceutical Science; Psychology.