Dr. Petra Ehling

Postdoctoral researcher

University Hospital Muenster
Neurology Clinic – Department of Inflammatory Disorders of the Nervous System and Neurooncology
Institute of Neuropathophysiology
Mendelstr. 7
D-48149 Münster

E-mail: Petra.Ehling@uni-muenster.de

Petra Ehling

PhD in 2010

PhD Research Project

Adenylyl cyclase mediated signalling in thalamocortical relay neurons

Promotion Committee

Prof. Dr. Thomas Budde (Supervisor)
Prof. Dr. Norbert Sachser
Prof. Dr. Hans-Christian Pape

Actual research field

Pathophysiological role of ion channels in neuroinflammatory and neurodegenerative disorders


Balfanz S*, Ehling P*, Wachten S*, Jordan N, Erber J, Mujagic S, Baumann A. Functional characterization of transmembrane adenylyl cyclases from the Honeybee brain. Insect Biochemistry and Molecular Biology 42: 435-45, 2012. * equal contribution

Bista P, Meuth SG, Kanyshkova T, Cerina M, Pawlowski M, Ehling P, Landgraf P, Borsotto M, Heurteaux C, Pape H-C, Baukrowitz T, Budde T. Identification of the muscarinic pathway underlying cessation of sleep-related burst activity in rat thalamocortical relay neurons. Pflugers Archiv : European journal of physiology 463: 89-102, 2011.

Decher N, Streit AK, Rapedius M, Netter MF, Marzian S, Ehling P, Schlichthorl G, Craan T, Renigunta V, Kohler A, Dodel RC, Navarro-Polanco RA, Preisig-Muller R, Klebe G, Budde T, Baukrowitz T, Daut J. RNA editing modulates the binding of drugs and highly unsaturated fatty acids to the open pore of Kv potassium channels. EMBO J 29: 2101-2113, 2010.

Ehling P, Bittner S, Bobak N, Schwarz T, Wiendl H, Budde T, Kleinschnitz C, Meuth S. Two pore domain potassium channels in cerebral ischemia: a focus on K2P9.1 (TASK3, KCNK9). Experimental & Translational Stroke Medicine 2: 14, 2010.

Ehling P, Bittner S, Budde T, Wiendl H, Meuth SG. Ion channels in autoimmune neurodegeneration. FEBS letters 585: 3836-42, 2011.

Ehling P, Kanyshkova T, Baumann A, Landgraf P, Meuth SG, Pape H-C, Budde T. Adenylyl Cyclases: Expression in the Developing Rat Thalamus and Their Role in Absence Epilepsy. Journal of molecular neuroscience : MN in press, 2012.

Hagenfeld D, Schulz T, Ehling P, Budde T, Schumacher U, Prehm P. Depolarization of the membrane potential by hyaluronan. Journal of Cellular Biochemistry 111: 858-864, 2010.

Hoff M, Balfanz S, Ehling P, Gensch T, Baumann A. A single amino acid residue controls Ca2+ signaling by an octopamine receptor from Drosophila melanogaster. The FASEB Journal 25: 2484-2491, 2011.

Kanyshkova T, Meuth P, Bista P, Liu Z, Ehling P, Caputi L, Döngi M, Chetkovich DM, Pape H-C, Budde T. Differential regulation of HCN channel isoform expression in thalamic neurons of epileptic and non-epileptic rat strains. Neurobiology of disease 45: 450-61, 2011.

Rankovic V, Ehling P, Coulon P, Landgraf P, Kreutz R. M, Munsch T, Budde T. Intracellular Ca2+ release-dependent inactivation of Ca2+ currents in thalamocortical relay neurons. Eur J Neurosci 31: 439-449, 2010.

Rankovic V, Landgraf P, Kanyshkova T, Ehling P, Meuth SG, Kreutz MR, Budde T, Munsch T. Modulation of Calcium-Dependent Inactivation of L-Type Ca Channels via β-Adrenergic Signaling in Thalamocortical Relay Neurons. PloS one 6: e27474, 2011.


*1982 in Gronau, Germany
2001-2006 Studies in Biology, University of Cologne
2006 Diploma thesis (Bachelor/Master), Institute of Complex Systems-4, Research Center Jülich, Title: “Charakterisierung von Adenylatzyklasen der Honigbiene Apis mellifera” (Supervisor: Prof. Dr. Arnd Baumann)
2006-2010 PhD research project, Institute of Physiology I, University of Münster
7/2010-12/2010 Postdoctoral researcher, Institute of Physiology I, University of Münster
since 1/2011 Postdoctoral researcher, Institute of Neurology and Institute of Neuropathophysiology, University Hospital Münster