Prof. Dr. Ralf Stanewsky
- Timing of locomotor activity and sleep in Drosophila melanogaster
- Genetic and molecular bases of the circadian clock in Drosophila melanogaster
- Circadian clock synchronisation by the daily natural environmental cycles of light and temperature
- See also: http://stanewsky.uni-muenster.de/research
- Classical and molecular genetics involving binary expression system (Gal4, Gal80, lexA) to interrogate circadian clock neuronal network function
- CRISPR to induce site directed mutations in endogenous genes controlling fly behaviour
- Real-time recordings of rhythmic gene expression using automated bioluminescence recordings and imaging
- Confocal microscopy to analyse spatial and temporal expression of clock proteins in the adult fly brain
- Quantitative methods to determine rhythmic locomotor activity and sleep (beam breaking and video-tracking technologies)
- Determining neuronal activity using genetically encoded Ca2+ sensors
R.E.F. Harper, P. Dayan, J.T. Albert, R. Stanewsky (2016). Sensory conflict disrupts activity of the Drosophila circadian network. Cell Rep 17:1711-1718
E. Buhl, A. Bradlaugh, M. Ogueta, K-F. Chen, R. Stanewsky, J.J.L. Hodge (2016). Quasimodo mediates daily and acute light effects on Drosophila clock neuron excitability. Proc Natl Acad Sci USA 113:13486-13491.
C. Chen, E. Buhl, M. Xu, V. Croset, J.S. Rees, K.S. Lilley, R. Benton, J.J. Hodge, R. Stanewsky (2015). Drosophila Ionotropic Receptor 25a mediates circadian clock resetting by temperature. Nature 527:516-520.
A. Simoni, W. Wolfgang, MP Topping, RG Kavlie, R. Stanewsky, and J. Albert (2014). A mechanosensory pathway to the Drosophila circadian clock. Science 343:525-528.
C. Gentile, H. Sehadova, A. Simoni, C. Chen, and R.Stanewsky (2013). Cryptochrome antagonizes synchronization of Drosophila’s circadian clock to temperature cycles. Current Biology 23: 185-195.
|Since 2016||Professor at the Institute for Neuro and Behavioural Biology, WWU Münster, Germany|
|2013-2016||Professor of Neurogenetics and Biological Timing, Department of Cell and Developmental Biology, University College London, London, UK|
|2006-2013||Professor and Chair of Neurobiology. School of Biological and Chemical Sciences, Queen Mary, University of London, UK|
|2002-2006||DFG Heisenberg Fellowship and Associate Professor (‘Privatdozent’) at University of Regensburg|
|2002||Habilitation and Venia legendi in Zoology|
|1998 - 2002||Group Leader at the Department of Zoology University of Regensburg|
|1994 - 1998||Postdoctoral Researcher at the Department of Biology, Brandeis University, USA|
|1990 - 1994||PhD Thesis at the Department for Developmental Biology, University of Cologne|
|1989 - 1990||Diploma thesis in Biology at the Department of Developmental Biology, University of Cologne|