• Explainable Artificial Intelligence (XAI)
• Hierarchical analysis of factor graphs
• Statistical boosting algorithms
• Methods for robust regression

2019 – 2023

Doctorate, University of Bonn

2016 – 2018

Studies Mathematics, University of Heidelberg, Degree M.Sc.

2012 – 2016

Studies Mathematics, University of Heidelberg, Degree B.Sc.

2025

• Ultra-fast extubation following cardiac surgery improves hemodynamic stability and reduces ICU workload
  Angiuli V, Rohner M, Wittmann M, Piekarski F, Kruse J, Silaschi M, Kunsorg A, Mayr A, Abulizi I, Speller J, Bakhtiary F, Velten M (2025) Frontiers in Cardiovascular Medicine 12, 1695955, doi: 10.3389/fcvm.2025.1695955.
• Implications of packed red bloods cells production and transfer on post transfusion hemoglobin increase
  Ehrentraut H, Massoth G, Delis A, Thewes B, Hoch J, Majchrzak M, Weber-Schehl M, Mayr A, Abulizi I, Speller J, Meybohm P, Steinisch A, Koessler J, Strauss AC, Wittmann M, Velten M (2025) Journal of Clinical Anesthesia 102, 111743, doi: 10.1016/j.jclinane.2025.111743.
• Approximate Lifted Model Construction
  Luttermann M, Speller J, Gehrke M, Braun T, Möller R, Hartwig M (2025) IJCAI-25 Proceedings of the 34th International Joint Conference on Artificial Intelligence. Montreal, IJCAI Organization, 9077–9085, doi: 10.24963/ijcai.2025/1009.
• Compression versus Accuracy: A Hierarchy of Lifted Models
  Speller J, Luttermann M, Gehrke M, Braun T (2025) ECAI-25 Proceedings of the 28th European Conference on Artificial Intelligence. Online, IOS Press, 5051–5058, doi: 10.3233/FAIA251420.
• Towards Explainability of Approximate Lifted Model Construction: A Geometric Perspective
  Speller J, Luttermann M, Gehrke M, Braun T (2025) Proceedings of the Joint Workshop on Humanities-Centred Artificial Intelligence and Formal & Cognitive Reasoning co-located with 48th German Conference on Artificial Intelligence.

2024

• Intestinal Oxalate Absorption, Enteric Hyperoxaluria, and Risk of Urinary Stone Formation in Patients with Crohn's Disease
  Siener R, Ernsten C, Speller J, Scheurlen C, Sauerbruch T, Hesse A (2024) Nutrients 16 (2), doi: 10.3390/nu16020264.

2023

• Robust gradient boosting for generalized additive models for location, scale and shape
  Speller J, Staerk C, Gude F, Mayr A (2023), doi: 10.1007/s11634-023-00555-5.
• Risk Profile of Patients with Brushite Stone Disease and the Impact of Diet
  Siener R, Pitzer MS, Speller J, Hesse A (2023) Nutrients 15 (18), doi: 10.3390/nu15184092.
• Linear or smooth? Enhanced model choice in boosting via deselection of base-learners
  Mayr A, Wistuba T, Speller J, Gude F, Hofner B (2023) Statistical Modelling 23 (5-6), 441–455, doi: 10.1177/1471082X231170045.
• Dissecting the genetic heterogeneity of gastric cancer
  Hess T, Maj C, Gehlen J, Borisov O, Haas SL, Gockel I, Vieth M, Piessen G, Alakus H, Vashist Y, Pereira C, Knapp M, Schüller V, Quaas A, Grabsch HI, Trautmann J, Malecka-Wojciesko E, Mokrowiecka A, Speller J, Mayr A, Schröder J, Hillmer AM, Heider D, Lordick F, Pérez-Aísa Á, Campo R, Espinel J, Geijo F, Thomson C, Bujanda L, Sopeña F, Lanas Á, Pellisé M, Pauligk C, Goetze TO, Zelck C, Reingruber J, Hassanin E, Elbe P, Alsabeah S, Lindblad M, Nilsson M, Kreuser N, Thieme R, Tavano F, Pastorino R, Arzani D, Persiani R, Jung JO, Nienhüser H, Ott K, Schumann RR, Kumpf O, Burock S, Arndt V, Jakubowska A, Ławniczak M, Moreno V, Martín V, Kogevinas M, Pollán M, Dąbrowska J, Salas A, Cussenot O, Boland-Auge A, Daian D, Deleuze JF, Salvi E, Teder-Laving M, Tomasello G, Ratti M, Senti C, De Re V, Steffan A, Hölscher AH, Messerle K, Bruns CJ, Sīviņš A, Bogdanova I, Skieceviciene J, Arstikyte J, Moehler M, Lang H, Grimminger PP, Kruschewski M, Vassos N, Schildberg C, Lingohr P, Ridwelski K, Lippert H, Fricker N, Krawitz P, Hoffmann P, Nöthen MM, Veits L, Izbicki JR, Mostowska A, Martinón-Torres F, Cusi D, Adolfsson R, Cancel-Tassin G, Höblinger A, Rodermann E, Ludwig M, Keller G, Metspalu A, Brenner H, Heller J, Neef M, Schepke M, Dumoulin FL, Hamann L, Cannizzaro R, Ghidini M, Plaßmann D, Geppert M, Malfertheiner P, Gehlen O, Skoczylas T, Majewski M, Lubiński J, Palmieri O, Boccia S, Latiano A, Aragones N, Schmidt T, Dinis-Ribeiro M, Medeiros R, Al-Batran SE, Leja M, Kupcinskas J, García-González MA, Venerito M, Schumacher J (2023) EBioMedicine 92, 104616–104616, doi: 10.1016/j.ebiom.2023.104616.
• GWAS meta-analysis of 16 790 patients with Barrett's oesophagus and oesophageal adenocarcinoma identifies 16 novel genetic risk loci and provides insights into disease aetiology beyond the single marker level.
  Schröder J, Chegwidden L, Maj C, Gehlen J, Speller J, Böhmer AC, Borisov O, Hess T, Kreuser N, Venerito M, Alakus H, May A, Gerges C, Schmidt T, Thieme R, Heider D, Hillmer AM, Reingruber J, Lyros O, Dietrich A, Hoffmeister A, Mehdorn M, Lordick F, Stocker G, Hohaus M, Reim D, Kandler J, Müller M, Ebigbo A, Fuchs C, Bruns CJ, Hölscher AH, Lang H, Grimminger PP, Dakkak D, Vashist Y, May S, Görg S, Franke A, Ellinghaus D, Galavotti S, Veits L, Weismüller J, Dommermuth J, Benner U, Rösch T, Messmann H, Schumacher B, Neuhaus H, Schmidt C, Wissinowski TT, Nöthen MM, Wellcome T C, Esophageal A G, Barrett's a E, Dong J, Ong JS, Buas MF, Thrift AP, Vaughan TL, Tomlinson I, Whiteman DC, Fitzgerald RC, Jankowski J, Vieth M, Mayr A, Gharahkhani P, MacGregor S, Gockel I, Palles C, Schumacher J (2023) Gut 72 (4), 612–623, doi: 10.1136/gutjnl-2021-326698.

2022

• Robust statistical boosting with quantile-based adaptive loss functions
  Speller J, Staerk C, Mayr A (2022) International Journal of Biostatistics 19 (1), 111–119, doi: 10.1515/ijb-2021-0127.

2026

• Speller, Jan; Luttermann, Malte; Gehrke, Marcel; Braun, Tanya 2026: “Inducing Comparability of Factorised Probability Distributions”. 3rd Logic and AI Meet-up, Hagen, Mar 19, 2026.

2025

• Speller, Jan; Luttermann, Malte; Gehrke, Marcel; Braun, Tanya 2025: “Compression versus Accuracy: A Hierarchy of Lifted Models”. 28th European Conference on Artificial Intelligence (ECAI 2025), Bologna, Oct 29, 2025.
• Speller, Jan 2025: “Towards Explainability of Approximate Lifted Model Construction: A Geometric Perspective”. Joint Workshop on Humanities-Centred Artificial Intelligence and Formal & Cognitive Reasoning co-located with 48th German Conference on Artificial Intelligence, Potsdam, Sep 16, 2025.DOI: 10.25592/uhhfdm.17946.