Prof. Steiner: Research and teaching

 
Research Foci

Formulierung von anspruchsvollen pharmazeutischen Wirkstoffen (u.a. schwer wasserlösliche Wirkstoffe)

Herstellung von Wirkstoffnanopartikeln und nanopartikuläre Lipidträgersysteme mittels verschiedener Technologien

Einarbeitung von nanopartikulären Systemen in orodispersible und mukoadhäsive Formen

2D-Druck von wirkstoffhaltigen Tinten auf geeignete Trägersysteme

CV

Academic Education

Promotion zum Dr.-Ing. an der Technischen Universität Braunschweig
Studienabschluss zum Dipl.-Ing. an der Technischen Universität Braunschweig

Positions

Universitätsprofessur für Pharmazeutische Technologie, Universität Münster / Stiftungsprofessur der Rottendorf Stiftung
Juniorprofessur für Pharmazeutische Technologie, Universität Tübingen
Wissenschaftliche Mitarbeiterin (PostDoc) am Institut für Pharmazeutische Technologie und Biopharmazie, Technische Universität Braunschweig
Senior Formulation Scientist & Project Manager, NextPharma GmbH
Wissenschaftliche Mitarbeiterin am Institut für Partikeltechnik, Technische Universität Braunschweig
Publications

  • , , , , and . . “Formulation of poorly water-soluble drugs in lipid nanocarriers: a suitable approach for taste masking or bitter-taste enhancing?” International Journal of Pharmaceutics 699 126993. doi: 10.1016/j.ijpharm.2026.126993.
  • , , and . “Influence of poloxamer used as emulsifier on the crystallization temperature of trimyristin nanodroplets.” contribution to the 13th World Meeting of Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Rotterdam, doi: 10.24355/dbbs.084-202607141240-0.
  • , , and . “Milling of poorly water-soluble drugs in oil via dual centrifugation - A closer look at stabilization and application on orodispersible films.” Journal of Drug Delivery Science and Technology 126 108735. doi: 10.1016/j.jddst.2026.108735.

  • , , and . . “Autoclaving behavior of trimyristin nanoemulsions stabilized with different poloxamers.” International Journal of Pharmaceutics 673 125376. doi: 10.1016/j.ijpharm.2025.125376.
  • , , , , , and . “Novel Strategies for the Formulation of Poorly Water-Soluble Drug Substances by Different Physical Modification Strategies with a Focus on Peroral Applications.” Pharmaceuticals 18 (8) 1089. doi: 10.3390/ph18081089.
  • , and . . “Development and application of a novel tracer system for the evaluation of temperature exposure of lipid nanoparticles in spray drying and dual centrifugation.” European journal of pharmaceutics and biopharmaceutics 217 114889. doi: 10.1016/j.ejpb.2025.114889.
  • , , , and . . “Embedding lipid nanodispersions in matrices: preparation of solid dosage forms with high lipid content and structural investigations using atomic force microscopy.” European Journal of Pharmaceutical Sciences 215 107279. doi: 10.1016/j.ejps.2025.107279.
  • , , and . . “Evaluation of emulsification behavior of two dual centrifuge types aided by CFD simulation.” International Journal of Pharmaceutics 686 126366. doi: 10.1016/j.ijpharm.2025.126366.

  • , , , and . . “Critical View on the Qualification of Electronic Tongues Regarding Their Performance in the Development of Peroral Drug Formulations with Bitter Ingredients.” Pharmaceutics 16: 658–658. doi: 10.3390/pharmaceutics16050658.

  • , , , , and . . “Preparation of Nanosized Pharmaceutical Formulations by Dual Centrifugation.” Pharmaceuticals 16: 1519. doi: 10.3390/ph16111519.
  • , , and . . “Embedding of poorly water-soluble drugs in orodispersible films - Comparison of five formulation strategies.” Pharmaceutics 15 (17): 1–22. doi: 10.3390/pharmaceutics15010017.

  • , , and . . “Processing of lipid nanodispersions into solid powders by spray drying.” Pharmaceutics 14 (11): 1–17. doi: 10.3390/pharmaceutics14112464.

  • , , and . . “Orodispersible films: A delivery platform for solid lipid nanoparticles?” Pharmaceutics 13 (12): 1–17. doi: 10.3390/pharmaceutics13122162.
  • , and . . “Influence of process and formulation parameters on the preparation of solid lipid nanoparticles by dual centrifugation.” International Journal of Pharmaceutics: X 3: 1–11. doi: 10.1016/j.ijpx.2021.100085.

  • , , and . . “SOFTs – Structured orodispersible film templates.” European journal of pharmaceutics and biopharmaceutics 137: 209–217. doi: 10.1016/j.ejpb.2019.03.001.
  • , , and . . “Model-based description of disintegration time and dissolution rate of nanoparticle-loaded orodispersible films.” European Journal of Pharmaceutical Sciences 132: 18–26. doi: 10.1016/j.ejps.2019.02.029.

  • , , and . . “Instant ODFs – Development of an intermediate, nanoparticle-based product platform for individualized medication.” European journal of pharmaceutics and biopharmaceutics 126: 149–158. doi: 10.1016/j.ejpb.2017.04.014.
  • , , , , and . . “Comparative study on disintegration methods for oral film preparations.” European journal of pharmaceutics and biopharmaceutics 132: 50–61. doi: 10.1016/j.ejpb.2018.09.005.

  • , , , , , , , , , , and . . “Novel strategies for the formulation and processing of poorly watersoluble drugs.” European journal of pharmaceutics and biopharmaceutics 126: 40–56. doi: 10.1016/j.ejpb.2017.05.008.
  • , , and . . “Redispersion of Nanoparticle-Loaded Orodispersible Films: Preservation of Particle Fineness.” Chemie Ingenieur Technik 89: 1034–1040. doi: 10.1002/cite.201600139.
  • , and . . Deutsche (DE102017103346 A1) und internationale Patentanmeldung (WO 2018/149983A1), Titel: "Structured orodispersible films"

  • , , and . . “Efficient production of nanoparticle-loaded orodispersible films by process integration in a stirred media mill.” International Journal of Pharmaceutics 511: 804–813. doi: 10.1016/j.ijpharm.2016.07.058.
  • , , , and . . “Breakage, temperature dependency and contamination of Lactose during ball milling in ethanol.” Advanced Powder Technology 27: 1700–1709. doi: 10.1016/j.apt.2016.05.034.
Supervised Doctoral Studies
  • Steiner, Denise : “Embedding of lipid nanodispersions in ODFs”. 7th APV Winter Conference: ODx and MBx - orodispersible and mucoadhesive buccal formulations: Novel technologies, new products, future opportunities, Innsbruck, .
  • Steiner, Denise : “Evaluation of drying behaviour and temperature exposure of lipid nanodispersions during spray drying ”. International Congress on Particle Technology, Nürnberg, .
  • Steiner, Denise : „Wirkstoff Meets Lipid - Nanopartikuläre Lipidträgersysteme eingebettet in feste Matrizes“. DPhG-Vortrag Regionalgruppe Südbaden, Freiburg, .
  • Steiner, Denise : “Processing of lipid nanodispersions into solid formulations by spray drying”. 13. World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Rotterdam, .
  • Steiner, Denise : “Embedding solid lipid nanoparticles in orodispersible films - A feasibility study”. 4. Braunschweig International Symposium on Pharmaceutical Engineering Research, Braunschweig, .
  • Steiner, Denise; Finke, Jan : “Instant preparations for orodispersible films”. 3. APV Winterkonferenz zum Thema “Individualized Medicines for oral use – visions and challenges”, Innsbruck, .
  • Steiner, Denise : “Individualized medication with poorly water-soluble APIs – Instant ODFs”. 2. Europeance Conference on Pharmaceutics, Krakau, .
  • Steiner, Denise : “Loading nanoparticular suspensions on drug-free orodispersible films”. International Congress on Particle Technology, Nürnberg, .
  • Steiner, Denise : “Efficient production of nanoparticle-loaded orodispersible films by process integration in a stirred media mill”. 1. Symposium on Pharmaceutical Engineering Research, Braunschweig, .
  • Steiner, Denise : “Stirred media milling of an organic model compound in ethanol”. 6. International Congress on Pharmaceutical Engineering, Graz, .

  • Teaching

    Lecture:

    "Pharmazeutische Technologie einschließlich Medizinprodukte" (5th, 6th and 7th semester)

    Seminar:

    "Qualitätssicherung bei Herstellung und Prüfung von Arzneimitteln"

Staff

Postdocs, Dissertation, MSc