RESEARCH - Andrea Rentmeister
Biological Chemistry and Biomolecular Label Chemistry
Research in the Rentmeister group focuses on RNA at the interface of chemistry and biochemistry. We aim to understand the mechanisms and ultimately control the processes affecting mRNA expression and turnover. To this end we develop chemical tools for manipulation, analysis, and control of mRNA at the molecular level and implement them in living cells and in vivo. Small alterations at the molecular level are an ideal way to probe biochemical mechanisms in the complex cellular context, as they can be introduced site-specifically using enzymes. Therefore, the chemical and chemo-enzymatic approaches developed in our lab represent a powerful strategy to address biological questions and probe biological systems.
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