• Pre-prints

    Elsässer M, Feitosa-Araujo E, Lichtenauer S, Wagner S, Fuchs P, Giese J, Kotnik F, Hippler M, Maurino VG, Finkemeier I, Schallenberg-Rüdinger M, Schwarzländer M* (2020) Photosynthetic activity triggers pH and NAD redox signatures across plant cell compartments.

    Ugalde JM, Fecker L, Schwarzländer M, Müller-Schüssele SJ, Meyer AJ
    Live monitoring of ROS-induced cytosolic redox changes with roGFP2-based sensors in plants.

    Balparda M, Elsässer M, Badia MB, Giese J, Bovdilova A, Hüdig M, Reinmuth L, Schwarzländer M, Finkemeier I, Schallenberg-Rüdinger M, Maurino VG
    Acetylation of conserved lysines fine-tune mitochondrial malate dehydrogenase activity in land plants

  • 2022

    Giese J, Eirich J, Post F, Schwarzländer M, Finkemeier I (2022) Mass spectrometry-based quantitative cysteine redox proteome profiling of isolated mitochondria using differential iodoTMT labelling.
    Methods Mol Biol. 2363: 215-234                                                                                                                                                                                                    

  • 2021

    Schwarzländer M*, Zurbriggen MD* (2021) Sensors and Controllers – For and From Plants.
    Plant Physiol. in press

    Lee CP, Elsässer M, Fuchs P, Fenske R, Schwarzländer M, Millar AH (2021) The versatility of plant organic acid metabolism in leaves is underpinned by mitochondrial malate-citrate exchange.
    Plant Cell. in press

    Lima VF, Erban A, Daubermann AG, Freire FBS, Porto NP, Cândido‐Sobrinho S, Medeiros DB,
    Schwarzländer M, Fernie AR, dos Anjos L, Kopka J, Daloso DM (2021) Establishment of a GC-MS-based 13C-positional isotopomer approach suitable for investigating metabolic fluxes in plant primary metabolism.
    Plant J
    . in press

    Feitosa Araujo E, da Fonseca Pereira P, Knorr LS, Schwarzländer M, Nunes-Nesi A (2021) NAD meets ABA: connecting cellular metabolism and hormone signaling.
    Trends Plant Sci
    . in press

    Kroll JB, Schwarzländer M*, Smith EN (2021) NAD redox monitoring with the fluorescent biosensor Peredox-mCherry.
    Trends Plant Sci. 26(10): 1087-1088

    Smith EN, Schwarzländer M, Ratcliffe RG, Kruger NJ (2021) Shining a light on NAD- and NADP-based metabolism in plants.
    Trends Plant Sci. 26(10): 1072-1086

    Moseler A, Kruse I, Maclean A, Pedroletti L, Franceschetti M, Wagner S, Wehler R, Fischer-Schrader K, Poschet G, Wirtz M, Dörmann P, Hildebrandt TM, Hell R, Schwarzländer M, Balk J, Meyer AJ (2021) The function of GRXS15 is required for lipoyl-dependent dehydrogenases in mitochondria.
    Plant Physiol. 186(3): 1507-1525

    Ugalde JM, Fuchs P, Nietzel T, Cutolo EA, Vothknecht U, Holuigue L, Schwarzländer M, Müller-Schüssele SJ, Meyer AJ (2021) Chloroplast-derived photo-oxidative stress triggers coupled redox dynamics between subcellular compartments.
    Plant Physiol. 186(1): 125-141

    Müller-Schüssele SJ, Schwarzländer M, Meyer AJ (2021) Live monitoring of plant redox and energy physiology with genetically-encoded biosensors.
    Plant Physiol. 186(1): 93-109

    Meyer AJ*, Dreyer A, Ugalde JM, Feitosa-Araujo, Dietz KJ*, Schwarzländer M* (2021) Shifting paradigms and novel players in Cys-based redox regulation and ROS signaling in plants - and where to go next.
    Biol Chem. 402(3): 399-423

  • 2020

    Feitosa Araujo E, da Fonseca Pereira P, Pena MM, Barbosa Medeiros D, Perez de Souza L, Weber APM, Araújo WL, Fernie AR, Schwarzländer M, Nunes-Nesi A (2020) Changes in intracellular nicotinamide adenine dinucleotide status affect stomatal development in an abscisic acid-dependent manner.
    Plant J. 104(5): 1149-1168

    Steinbeck J, Fuchs P, Negroni YL, Elsässer M, Lichtenauer S, Stockdreher Y, Feitosa-Araujo E, Kroll JB, Niemeier JO, Humberg C, Smith E, Mai M, Nunes-Nesi A, Meyer AJ, Zottini M, Morgan B, Wagner S, Schwarzländer M* (2020) In vivo NADH/NAD+ biosensing reveals the dynamics of cytosolic redox metabolism in plants.
    Plant Cell. 32(10): 3324-3345

    Müller-Schüssele SJ, Wang R, Gütle DD, Romer J, Rodriguez-Franco M, Scholz M, Lüth VM, Kopriva S, Dörmann P, Schwarzländer M, Reski R, Hippler M, Meyer AJ (2020) Chloroplasts require glutathione reductase to balance reactive oxygen species and maintain efficient photosynthesis.
    Plant J. 103(3): 1140-1154

    Brenig K, Grube L, Schwarzländer M, Köhrer K, Stühler K, Poschmann G (2020) The proteomic landscape of cysteine oxidation that underpins retinoic acid-induced neuronal differentiation.
    J Proteome Res. 19(5): 1923-1940

    Møller IM, Igamberdiev AU, Bykova NV, Rasmusson AG, Finkemeier I, Schwarzländer M (2020) Matrix redox physiology governs the regulation of plant mitochondrial metabolism through post-translational protein modifications.
    Plant Cell. 32: 573-594

    Fuchs P, Rugen N, Carrie C, Elsässer M, Finkemeier I, Giese J, Hildebrandt TM, Kühn K, Maurino VG, Ruberti C, Schallenberg-Rüdinger M, Steinbeck J, Braun HP, Eubel H, Meyer EH, Müller-Schüssele SJ, Schwarzländer M* (2020) Single organelle function and organization as estimated from Arabidopsis mitochondrial proteomics.
    Plant J. 101(2): 420-441

    Nietzel T, Mostertz J, Ruberti C, Née G, Fuchs P, Wagner S, Moseler A, Müller-Schüssele SJ, Benamar A, Poschet G, Büttner M, Møller IM, Lillig CH, Macherel D, Wirtz M, Hell R, Finkemeier I, Meyer AJ, Hochgräfe F, Schwarzländer M* (2020) Redox-mediated kick-start of mitochondrial energy metabolism drives resource-efficient seed germination.
    Proc Natl Acad Sci USA. 117(1): 741-751

  • 2019-2016


    Zhang N, Meng Y, Li X, Zhou Y, Ma L, Fu L, Schwarzländer M, Liu H, Xiong Y (2019) Metabolite-induced TOR signaling regulates the circadian clock in Arabidopsis.
    Proc Natl Acad Sci USA. 116(51): 25395-25397

    Bangash SAK, Müller-Schüssele SJ, Solbach D, Jansen M, Fiorani F, Schwarzländer M, Kopriva S, Meyer AJ (2019) Low-glutathione mutants are impaired in growth but do not show an increased sensitivity to moderate water deficit.
    PLoS One. e0220589

    Wagner S*, Steinbeck J, Fuchs P, Lichtenauer S, Elsässer M, Schippers JHM, Nietzel T, Ruberti C, Van Aken O, Meyer AJ, Van Dongen JT, Schmidt RR, Schwarzländer M* (2019) Multiparametric real-time sensing of cytosolic physiology links hypoxia responses to mitochondrial electron transport.
    New Phytol. 224(4): 1668-1684

    Marty L, Bausewein D, Müller C, Bangash SAK, Moseler A, Schwarzländer M, Müller-Schüssele SJ, Zechmann B, Riondet C, Balk J, Wirtz M, Hell R, Reichheld J-P, Meyer AJ (2019) Arabidopsis glutathione reductase 2 is indispensable in plastids, while mitochondrial glutathione is safeguarded by additional reduction and transport systems.
    New Phytol. 224(4): 1569-1584

    Schwarzländer M*, Fuchs P (2019) Keeping mitochondrial alternative oxidase reduced and active in vivo does not require thioredoxin o1.
    Plant Cell Physiol. 60(11): 2357-2359

    Nietzel T, Elsässer M, Ruberti C, Steinbeck MJ, Ugalde JM, Fuchs P, Wagner S, Ostermann L, Moseler A, Lemke P, Fricker MD, Müller-Schüssele SJ, Moerschbacher BM, Costa A, Meyer AJ, Schwarzländer M* (2019) The fluorescent protein sensor roGFP2-Orp1 monitors in vivo H2O2 and thiol redox integration and elucidates intracellular H2O2 dynamics during elicitor-induced oxidative burst in Arabidopsis.
    New Phytol. 221(3): 1649-1664


    Behera S, Xu Z, Luoni L, Bonza C, Doccula FG, DeMichelis MI, Morris RJ, Schwarzländer M, Costa A (2018) Cellular Ca2+ signals generate defined pH signatures in plants.
    Plant Cell. 30(11): 2704-2719

    Voon CP, Guan X, Sun Y, Sahu A, Chan MN, Gardeström P, Wagner S, Fuchs P, Nietzel T, Versaw WK, Schwarzländer M, Lim BL (2018) ATP compartmentation in plastids and cytosol of Arabidopsis thaliana revealed by fluorescent protein sensing.
    Proc Natl Acad Sci USA. 115 (45) e10778-e10787

    Hartmann SK, Stockdreher Y, Wandrey G, Tehrani HH, Zambanini T, Meyer AJ, Büchs J, Blank LM, Schwarzländer M*, Wierckx N* (2018) Online in vivo monitoring of cytosolic NAD redox dynamics in Ustilago maydis.
    Biochim Biophys Acta. 1859(10): 1015-1024

    Scuffi D, Nietzel T, Di Fino LM, Meyer AJ, Lamattina L, Schwarzländer M, Laxalt AM, García-Mata C (2018) Hydrogen sulfide increases production of NADPH oxidase-dependent hydrogen peroxide and phospholipase D-derived phosphatidic acid in guard cell signaling.
    Plant Physiol. 176(3): 2532-2542

    Wagner S*, Van Aken O, Elsässer M, Schwarzländer M* (2018) Mitochondrial energy signaling and its role in the oxygen stress response of plants.
    Plant Physiol. 176(2): 1156-1170

    Finkemeier I*, Schwarzländer M* (2018) Mitochondrial regulation in the photosynthetic cell: principles and concepts.
    Annual Plant Reviews: Plant Mitochondria 2nd Edition, Chapter 7, Wiley. 185-226


    Schwarzländer M*, Fuchs P (2017) Plant mitochondrial membranes: adding structure and new functions to respiratory physiology.
    Curr Opin Plant Biol. 40: 147-157

    Zambanini T, Hartmann SK, Schmitz LM, Büttner L, Tehrani HH, Geiser E, Beudels M, Venc D, Wandrey G, Büchs J, Schwarzländer M, Blank LM, Wierckx N (2017) Promoters from the itaconate cluster of Ustilago maydis are induced by nitrogen depletion.
    Fungal Biol Biotechnol. 4: 11

    De Col V, Fuchs P, Nietzel T, Elsässer M, Voon CP, Candeo A, Seeliger I, Fricker MD, Grefen C, Møller IM, Bassi A, Lim BL, Zancani M, Meyer AJ, Costa A, Wagner S*, Schwarzländer M* (2017) ATP sensing in living plant cells reveals tissue gradients and stress dynamics of energy physiology.
    eLIFE. e26770

    Attacha S, Solbach D, Bela K, Moseler A, Wagner S, Schwarzländer M, Aller I, Müller SJ, Meyer A. (2017) Glutathione peroxidase-like enzymes cover five distinct cell compartments and membrane-surfaces in Arabidopsis thaliana.
    Plant Cell Environ. 40(8): 1281-1295

    Xing S, Mehlhorn DG, Wallmeroth N, Asseck LY, Kar R, Voss A, Denninger P, Schmidt VAF, Schwarzländer M, Stierhof Y-D, Grossmann G, Grefen C. (2017) Loss of GET pathway orthologues in Arabidopsis thaliana causes root hair growth defects and affects SNARE abundance.
    Proc Natl Acad Sci USA. 114(8): E1544-E1553

    Teardo E, Carraretto L, Wagner S, Formentina E, Behera S, De Bortoli S, Larosa V, Fuchs P, Lo Schiavo F, Raffaello A, Rizzuto R, Costa A, Schwarzländer M, Szabò I (2017) Physiological characterization of a plant mitochondrial calcium uniporter in vitro and in vivo.
    Plant Physiol. 173(2): 1355-1370

    Senkler J, Senkler M, Eubel H, Hildebrandt T, Lengwenus C, Schertl P, Schwarzländer M, Wagner S, Wittig I, Braun H-P. (2017) The mitochondrial complexome of Arabidopsis thaliana.
    Plant J. 89(6): 1079-1092

    Nietzel T, Hochgräfe F, Mostertz J, Schwarzländer M* (2017) Redox regulation of mitochondrial proteins and proteomes by cysteine thiol switches.
    Mitochondrion. 33: 72-83


    Welchen E, Schmitz J, Fuchs P, García L, Wagner S, Schmidt J, Schertl P, Braun HP, Schwarzländer M, Gonzalez DH, Maurino VG (2016) D-Lactate dehydrogenase links methylglyoxal degradation to the electron transport chain through cytochrome c.
    Plant Physiol. 172 (2): 901-912

    Demaurex N*, Schwarzländer M* (2016) Mitochondrial flashes: dump superoxide and dance with protons now.
    Antiox Redox Signal. 25 (9): 550-551

    Loro G, Wagner S, Doccula FG, Behera S, Weinl S, Kudla J, Schwarzländer M, Costa A, Zottini M (2016) Chloroplast-specific in vivo Ca2+ imaging using Yellow Cameleon fluorescent protein sensors reveals organelle-autonomous Ca2+ signatures in the stroma.
    Plant Physiol. 171 (4): 2317-2330

    Huang S, Van Aken O, Schwarzländer M, Belt K, Millar AH (2016) The roles of mitochondrial reactive oxygen species in cellular signalling and stress response in plants.
    Plant Physiol. 171 (3): 1151-1159

    Wagner S, De Bortoli S, Schwarzländer M*, Szabò I* (2016) Mitochondrial Ca2+ regulation in plants versus animals.
    J Exp Bot. 67 (13): 3809-3829

    Morgan B*, Schwarzländer M* (2016) Fluoreszierende Proteinsensoren für die Redoxregulation in lebenden Zellen.
    BIOspektrum. 22 (3): 260-263

    Schwarzländer M*, Dick TP, Meyer AJ, Morgan B* (2016) Dissecting redox biology using fluorescent protein sensors.
    Antiox Redox Signal. 24 (13): 680-712

    Breckwoldt MO, Armoundas AA, Aon MA, O‘Rourke B, Schwarzländer M, Bendszus M, Dick TP, Kurz FT (2016) Mitochondrial redox and pH signaling occurs in axonal and synaptic organelle clusters.
    Sci Rep. 6: 23251

    Fuchs R, Kopischke M, Kuhns C, Hause G, Meyer AJ, Schwarzländer M, Fricker MD, Lipka V (2016) Immobilized subpopulations of leaf epidermal mitochondria mediate PENETRATION2-dependent pathogen entry control in Arabidopsis.
    Plant Cell. 28 (1): 130-145

  • 2015 - 2008


    Wagner S, Behera S, De Bortoli S, Logan DC, Fuchs P, Carraretto L, Teardo E, Cendron L, Nietzel T, Füßl M, Doccula FG, Navazio L, Fricker MD, Van Aken O, Finkemeier I, Meyer AJ, Szabò I, Costa A, Schwarzländer M* (2015) The EF-hand Ca2+-binding protein MICU choreographs mitochondrial Ca2+ dynamics in Arabidopsis.
    Plant Cell. 27 (11): 3190-3212

    Moseler A, Aller I, Wagner S, Nietzel T, Przybyla-Toscano J, Mühlenhoff U, Lill R, Berndt C, Rouhier N, Schwarzländer M, Meyer AJ (2015) The mitochondrial monothiol glutaredoxin S15 is essential for maturation of iron-sulfur proteins in Arabidopsis thaliana.
    Proc Natl Acad Sci USA. 112 (44): 13735-13740

    Wagner S, Nietzel T, Aller I, Costa A, Fricker MD, Meyer AJ, Schwarzländer M* (2015) Analysis of plant mitochondrial function using fluorescent protein sensors.
    Methods Mol Biol. 1305: 241-252

    Riemer J*, Schwarzländer M*, Conrad M*, Herrmann JM* (2015) Thiol switches in mitochondria: operation and physiological relevance.
    Biol Chem. 396 (5): 465-482

    Kosmacz M, Parlanti S, Schwarzländer M, Kragler F, Licausi F, Van Dongen JT (2015) The stability and nuclear localization of the transcription factor RAP2.12 are dynamically regulated by oxygen concentration.
    Plant Cell Environ. 38 (6): 1094-1103


    Littlejohn G, Meckel T, Schwarzländer M, Costa A (2014) Functional imaging in living plants – cell biology meets physiology.
    Front Plant Sci 5:740

    Braun H-P, Binder S, Brennicke A, Eubel H, Fernie AR, Finkemeier I, Klodmann J, König A-C, Kühn K, Meyer E, Obata T, Schwarzländer M, Takenaka M, Zehrmann A (2014) The life of plant mitochondrial complex I.
    Mitochondrion. 19 (B): 295-313

    Schwarzländer M*, Wagner S, Ermakova YG, Belousov VV, Radi R, Beckman JS, Buettner GR, Demaurex N, Duchen MR, Forman HJ, Fricker MD, Gems D, Halestrap AP, Halliwell B, Jakob U, Johnston IG, Jones NS, Logan DC, Morgan B, Müller FL, Nicholls DG, Remington SJ, Schumacker PT, Winterbourn CC, Sweetlove LJ, Meyer AJ, Dick TP, Murphy MP (2014) The ‘mitoflash’ probe cpYFP does not respond to superoxide.
    Nature. 514 (7523): E12-E14

    El Zawily AM, Schwarzländer M, Finkemeier I, Johnston IG, Benamar A, Cao Y, Gissot C, Meyer AJ, Wilson K, Datla R, Macherel D, Jones NS, Logan DC (2014) FRIENDLY regulates mitochondrial distribution, fusion, and quality control in Arabidopsis.
    Plant Physiol. 166 (2): 808-828

    Schaedler TA, Thornton JD, Kruse I, Schwarzländer M, Meyer AJ, van Veen HW, Balk J (2014) A conserved mitochondrial ATP-binding cassette transporter exports glutathione polysulfide for cytosolic metal cofactor assembly.
    J Biol Chem. 289 (34): 23264-23274

    Breckwoldt MO, Pfister F, Bradley PM, Marinković P, Williams PR, Brill MS, Plomer B, Schmalz A, St. Clair DK, Naumann R, Griesbeck O, Schwarzländer M, Godinho L, Bareyre FM, Dick TP, Kerschensteiner M, Misgeld T (2014) Multi-parametric optical analysis of mitochondrial redox signals during neuronal physiology and pathology in vivo.
    Nature Med. 20: 555-560


    Schwarzländer M, Finkemeier I (2013) Mitochondrial energy and redox signalling in plants.
    Antiox Redox Signal. 18 (16): 2122-2144


    Schwarzländer M*, Murphy MP, Duchen MR, Logan DC, Fricker MD, Halestrap AP, Müller FL, Rizzuto R, Dick TP, Meyer AJ, Sweetlove LJ (2012) Mitochondrial ‘flashes’: a radical concept repHined.
    Trends Cell Biol. 22 (10): 503-508

    Wirtz M, Beard KFM, Lee CP, Boltz A, Schwarzländer M, Fuchs C, Meyer AJ, Heeg C, Sweetlove LJ, Ratcliffe RG and Hell R (2012) Mitochondrial cysteine synthase complex regulates O-acetylserine biosynthesis in plants.
    J Biol Chem. 287 (33): 27941-27947

    Schwarzländer M, Logan DC, Johnston IG, Jones NS, Meyer AJ, Fricker MD, Sweetlove LJ (2012) Pulsing of membrane potential in individual mitochondria: a stress-induced mechanism to regulate respiratory bioenergetics in Arabidopsis.
    Plant Cell. 24 (3): 1188-1201

    Schwarzländer M, König AC, Sweetlove LJ, Finkemeier I (2012) The impact of impaired mitochondrial function on retrograde signalling: a meta-analysis of transcriptomic responses.
    J Exp Bot. 63 (4): 1735-1750


    Schwarzländer M*, Logan DC, Fricker MD, Sweetlove LJ* (2011) The circularly permuted yellow fluorescent protein cpYFP that has been used as a superoxide probe is highly responsive to pH but not superoxide in mitochondria: implications for the existence of superoxide "flashes".
    Biochem J. 437 (3): 381-387


    Williams TC, Poolman MG, Howden AJ, Schwarzländer M, Fell DA, Ratcliffe RG, Sweetlove LJ (2010) A genome-scale metabolic model accurately predicts fluxes in central carbon metabolism under stress conditions.
    Plant Physiol. 154 (1): 311-323


    Marty L, Siala W, Schwarzländer M, Fricker MD, Wirtz M, Sweetlove LJ, Meyer Y, Meyer AJ, Reichheld JP, Hell R (2009) The NADPH-dependent thioredoxin system constitutes a functional backup for cytosolic glutathione reductase in Arabidopsis.
    Proc Natl Acad Sci USA.106 (22): 9109-9114

    Lehmann M, Schwarzländer M, Sirikantaramas S, Burow M, Olsen CE, Fricker MD, Møller BL, Fernie AR, Sweetlove LJ, Laxa M (2009) The metabolic response of Arabidopsis roots to oxidative stress is distinct from that of heterotrophic cells in culture and highlights a complex relationship between the levels of transcripts, metabolites and flux.
    Mol Plant. 2 (3): 390-406

    Schwarzländer M, Fricker MD, Sweetlove LJ (2009) Monitoring the in vivo redox state of plant mitochondria: Effect of respiratory inhibitors, abiotic stress and assessment of recovery after oxidative challenge.
    Biochim Biophys Acta. 1787 (5): 468-475


    Schwarzländer M, Fricker MD, Müller C, Marty L, Brach T, Novak J, Sweetlove LJ, Hell R, Meyer AJ (2008) Confocal imaging of glutathione redox poise in living plant cells.
    J Microsc. 231 (2): 299-316

    Forner J, Hölzle A, Jonietz C, Thuss S, Schwarzländer M, Weber B, Meyer RC, Binder S (2008)
    Mitochondrial mRNA polymorphisms in different Arabidopsis accessions.
    Plant Physiol. 148 (2): 1106-1116

    Morgan MJ, Lehmann M, Schwarzländer M, Baxter CJ, Sienkiewicz-Porzucek A, Williams TC, Schauer N, Fernie AR, Fricker MD, Ratcliffe RG, Sweetlove LJ, Finkemeier I (2008)
    Decrease in manganese superoxide dismutase leads to reduced root growth and affects TCA cycle flux and mitochondrial redox homeostasis.
    Plant Physiol. 147 (1): 101-114

*corresponding author