PUBLICATIONS

  • 2023

  • 2022

    • Guzha A, Whitehead P, Ischebeck T, Chapman KD. Lipid Droplets: Packing Hydrophobic Molecules Within the Aqueous Cytoplasm. Annu Rev Plant Biol. 2022 Nov 22; https://doi.org/10.1146/annurev-arplant-070122-021752

    • Düking T, Spieth L, Berghoff SA, Piepkorn L, Schmidke AM, Mitkovski M, Kannaiyan N, Hosang L, Scholz P, Shaib AH, Schneider LV, Hesse D, Ruhwedel T, Sun T, Linhoff L, Trevisiol A, Köhler S, Pastor AM, Misgeld T, Sereda M, Hassouna I, Rossner MJ, Odoardi F, Ischebeck T, de Hoz L, Hirrlinger J, Jahn O, Saher G. Ketogenic diet uncovers differential metabolic plasticity of brain cells. Sci Adv. 2022 Sep 16;8(37):eabo7639; https://doi.org/10.1126/sciadv.abo7639

    • Niemeyer PW, Irisarri I, Scholz P, Schmitt K, Valerius O, Braus GH, Herrfurth C, Feussner I, Sharma S, Carlsson AS, de Vries J, Hofvander P, Ischebeck T. A seed-like proteome in oil-rich tubers. Plant J. 2022 Oct;112(2):518-534; https://doi.org/10.1111/tpj.15964

    • Scholz P, Chapman KD, Mullen RT, Ischebeck T. Finding new friends and revisiting old ones - how plant lipid droplets connect with other subcellular structures. New Phytol. 2022 Nov;236(3):833-838; https://doi.org/10.1111/nph.18390

    • Kasper K, Abreu IN, Feussner K, Zienkiewicz K, Herrfurth C, Ischebeck T, Janz D, Majcherczyk A, Schmitt K, Valerius O, Braus GH, Feussner I, Polle A. Multi-omics analysis of xylem sap uncovers dynamic modulation of poplar defenses by ammonium and nitrate. Plant J. 2022 Jul;111(1):282-303; https://doi.org/10.1111/tpj.15802

    • Guzha A, McGee R, Scholz P, Hartken D, Lüdke D, Bauer K, Wenig M, Zienkiewicz K, Herrfurth C, Feussner I, Vlot AC, Wiermer M, Haughn G, Ischebeck T. Cell wall-localized BETA-XYLOSIDASE4 contributes to immunity of Arabidopsis against Botrytis cinerea. Plant Physiol. 2022 Jun 27;189(3):1794-1813; https://doi.org/10.1093/plphys/kiac165

    • Krawczyk HE, Sun S, Doner NM, Yan Q, Lim MSS, Scholz P, Niemeyer PW, Schmitt K, Valerius O, Pleskot R, Hillmer S, Braus GH, Wiermer M, Mullen RT, Ischebeck T. SEED LIPID DROPLET PROTEIN1, SEED LIPID DROPLET PROTEIN2, and LIPID DROPLET PLASMA MEMBRANE ADAPTOR mediate lipid droplet-plasma membrane tethering. Plant Cell. 2022 May 24;34(6):2424-2448; https://doi.org/10.1093/plcell/koac095

    • Krawczyk HE, Rotsch AH, Herrfurth C, Scholz P, Shomroni O, Salinas-Riester G, Feussner I, Ischebeck T. Heat stress leads to rapid lipid remodeling and transcriptional adaptations in Nicotiana tabacum pollen tubes. Plant Physiol. 2022 Jun 1;189(2):490-515; https://doi.org/10.1093/plphys/kiac127

    • Krüger L, Herzberg C, Wicke D, Scholz P, Schmitt K, Turdiev A, Lee VT, Ischebeck T, Stülke J. Sustained Control of Pyruvate Carboxylase by the Essential Second Messenger Cyclic di-AMP in Bacillus subtilis. mBio. 2022 Feb 8;13(1):e0360221; https://doi.org/10.1128/mbio.03602-21

    • Scholz P, Pejchar P, Fernkorn M, Škrabálková E, Pleskot R, Blersch K, Munnik T, Potocký M, Ischebeck T. DIACYLGLYCEROL KINASE 5 regulates polar tip growth of tobacco pollen tubes. New Phytol. 2022 Mar;233(5):2185-2202; https://doi.org/10.1111/nph.17930

    • Hertel R, Schöne K, Mittelstädt C, Meißner J, Zschoche N, Collignon M, Kohler C, Friedrich I, Schneider D, Hoppert M, Kuhn R, Schwedt I, Scholz P, Poehlein A, Martienssen M, Ischebeck T, Daniel R, Commichau FM. Characterization of glyphosate-resistant Burkholderia anthina and Burkholderia cenocepacia isolates from a commercial Roundup® solution. Environ Microbiol Rep. 2022 Feb;14(1):70-84; https://doi.org/10.1111/1758-2229.13022

  • 2021

    • Vollheyde K, Hornung E, Herrfurth C, Ischebeck T, Feussner I. Plastidial wax ester biosynthesis as a tool to synthesize shorter and more saturated wax esters. Biotechnol Biofuels. 2021 Dec 15;14(1):238; https://doi.org/10.1186/s13068-021-02062-1
    • Berghoff SA, Spieth L, Sun T, Hosang L, Depp C, Sasmita AO, Vasileva MH, Scholz P, Zhao Y, Krueger-Burg D, Wichert S, Brown ER, Michail K, Nave KA, Bonn S, Odoardi F, Rossner M, Ischebeck T, Edgar JM, Saher G. Neuronal cholesterol synthesis is essential for repair of chronically demyelinated lesions in mice. Cell Rep. 2021 Oct 26;37(4):109889; https://doi.org/10.1016/j.celrep.2021.109889

    • Pyc M, Gidda SK, Seay D, Esnay N, Kretzschmar FK, Cai Y, Doner NM, Greer MS, Hull JJ, Coulon D, Bréhélin C, Yurchenko O, de Vries J, Valerius O, Braus GH, Ischebeck T, Chapman KD, Dyer JM, Mullen RT. LDIP cooperates with SEIPIN and LDAP to facilitate lipid droplet biogenesis in Arabidopsis. Plant Cell. 2021 Sep 24;33(9):3076-3103; https://doi.org/10.1093/plcell/koab179

    • de Vries S, Fürst-Jansen JMR, Irisarri I, Dhabalia Ashok A, Ischebeck T, Feussner K, Abreu IN, Petersen M, Feussner I, de Vries J. The evolution of the phenylpropanoid pathway entailed pronounced radiations and divergences of enzyme families. Plant J. 2021 Aug;107(4):975-1002; https://doi.org/10.1111/tpj.15387

    • Horn PJ, Chapman KD, Ischebeck T. Isolation of Lipid Droplets for Protein and Lipid Analysis. Methods Mol Biol. 2021;2295:295-320; https://doi.org/10.1007/978-1-0716-1362-7_16

    • Doner NM, Seay D, Mehling M, Sun S, Gidda SK, Schmitt K, Braus GH, Ischebeck T, Chapman KD, Dyer JM, Mullen RT. Arabidopsis thaliana EARLY RESPONSIVE TO DEHYDRATION 7 Localizes to Lipid Droplets via Its Senescence Domain. Front Plant Sci. 2021 Apr 14;12:658961; https://doi.org/10.3389/fpls.2021.658961

    • Gömann J, Herrfurth C, Zienkiewicz A, Ischebeck T, Haslam TM, Hornung E, Feussner I. Sphingolipid long-chain base hydroxylation influences plant growth and callose deposition in Physcomitrium patens. New Phytol. 2021 Jul;231(1):297-314; https://doi.org/10.1111/nph.17345

    • Krüger L, Herzberg C, Rath H, Pedreira T, Ischebeck T, Poehlein A, Gundlach J, Daniel R, Völker U, Mäder U, Stülke J. Essentiality of c-di-AMP in Bacillus subtilis: Bypassing mutations converge in potassium and glutamate homeostasis. PLoS Genet. 2021 Jan 22;17(1):e1009092; https://doi.org/10.1371/journal.pgen.1009092
    • Berghoff SA, Spieth L, Sun T, Hosang L, Schlaphoff L, Depp C, Düking T, Winchenbach J, Neuber J, Ewers D, Scholz P, van der Meer F, Cantuti-Castelvetri L, Sasmita AO, Meschkat M, Ruhwedel T, Möbius W, Sankowski R, Prinz M, Huitinga I, Sereda MW, Odoardi F, Ischebeck T, Simons M, Stadelmann-Nessler C, Edgar JM, Nave KA, Saher G. Microglia facilitate repair of demyelinated lesions via post-squalene sterol synthesis. Nat Neurosci. 2021 Jan;24(1):47-60;  https://doi.org/10.1038/s41593-020-00757-6

     

  • 2020

    • de Vries J, Ischebeck T. Ties between Stress and Lipid Droplets Pre-date Seeds. Trends Plant Sci. 2020 Dec;25(12):1203-1214; https://doi.org/10.1016/j.tplants.2020.07.017
    • Scholz P, Anstatt J, Krawczyk HE, Ischebeck T. Signalling Pinpointed to the Tip: The Complex Regulatory Network That Allows Pollen Tube Growth. Plants (Basel). 2020 Aug 26;9(9):1098; https://doi.org/10.3390/plants9091098
    • Greer MS, Cai Y, Gidda SK, Esnay N, Kretzschmar FK, Seay D, McClinchie E, Ischebeck T, Mullen RT, Dyer JM, Chapman KD. SEIPIN Isoforms Interact with the Membrane-Tethering Protein VAP27-1 for Lipid Droplet Formation. Plant Cell. 2020 Sep;32(9):2932-2950; https://doi.org/10.1105/tpc.19.00771

    • Stenzel I, Ischebeck T, Vu-Becker LH, Riechmann M, Krishnamoorthy P, Fratini M, Heilmann I. Coordinated Localization and Antagonistic Function of NtPLC3 and PI4P 5-Kinases in the Subapical Plasma Membrane of Tobacco Pollen Tubes. Plants (Basel). 2020 Apr 3;9(4):452; https://doi.org/10.3390/plants9040452

    • Ischebeck T, Krawczyk HE, Mullen RT, Dyer JM, Chapman KD. Lipid droplets in plants and algae: Distribution, formation, turnover and function. Semin Cell Dev Biol. 2020 Dec;108:82-93; https://doi.org/10.1016/j.semcdb.2020.02.014

    • Kretzschmar FK, Doner NM, Krawczyk HE, Scholz P, Schmitt K, Valerius O, Braus GH, Mullen RT, Ischebeck T. Identification of Low-Abundance Lipid Droplet Proteins in Seeds and Seedlings. Plant Physiol. 2020 Mar;182(3):1326-1345; https://doi.org/10.1104/pp.19.01255

  • 2019

    • Djian, B., Hornung, E., Ischebeck, T. and Feussner, I. (2019) The green microalga Lobosphaera incisa harbors an arachidonate 15S‐lipoxygenase. Plant Biology, 21, 131-142; https://doi.org/10.1111/plb.12920
    • Alevra M, Mandad S, Ischebeck T, Urlaub H, Rizzoli SO, Fornasiero EF. A mass spectrometry workflow for measuring protein turnover rates in vivo. Nat Protoc. 2019 Dec;14(12):3333-3365; https://doi.org/10.1038/s41596-019-0222-y

    • Dormeyer M, Lentes S, Richts B, Heermann R, Ischebeck T, Commichau FM. Variants of the Bacillus subtilis LysR-Type Regulator GltC With Altered Activator and Repressor Function. Front Microbiol. 2019 Oct 9;10:2321; https://doi.org/10.3389/fmicb.2019.02321

    • Touraine B, Vignols F, Przybyla-Toscano J, Ischebeck T, Dhalleine T, Wu HC, Magno C, Berger N, Couturier J, Dubos C, Feussner I, Caffarri S, Havaux M, Rouhier N, Gaymard F. Iron-sulfur protein NFU2 is required for branched-chain amino acid synthesis in Arabidopsis roots. J Exp Bot. 2019 Mar 27;70(6):1875-1889; https://doi.org/10.1093/jxb/erz050

    • Wicke D, Schulz LM, Lentes S, Scholz P, Poehlein A, Gibhardt J, Daniel R, Ischebeck T, Commichau FM. Identification of the first glyphosate transporter by genomic adaptation. Environ Microbiol. 2019 Apr;21(4):1287-1305; https://doi.org/10.1111/1462-2920.14534

     

  • 2014-2018

    2018

    • Mandad S, Rahman RU, Centeno TP, Vidal RO, Wildhagen H, Rammner B, Keihani S, Opazo F, Urban I, Ischebeck T, Kirli K, Benito E, Fischer A, Yousefi RY, Dennerlein S, Rehling P, Feussner I, Urlaub H, Bonn S, Rizzoli SO, Fornasiero EF. The codon sequences predict protein lifetimes and other parameters of the protein life cycle in the mouse brain. Sci Rep. 2018 Nov 15;8(1):16913; https://doi.org/10.1038/s41598-018-35277-8
    • Fornasiero EF, Mandad S, Wildhagen H, Alevra M, Rammner B, Keihani S, Opazo F, Urban I, Ischebeck T, Sakib MS, Fard MK, Kirli K, Centeno TP, Vidal RO, Rahman RU, Benito E, Fischer A, Dennerlein S, Rehling P, Feussner I, Bonn S, Simons M, Urlaub H, Rizzoli SO. Precisely measured protein lifetimes in the mouse brain reveal differences across tissues and subcellular fractions. Nat Commun. 2018 Oct 12;9(1):4230; https://doi.org/10.1038/s41467-018-06519-0

    • Kretzschmar FK, Mengel LA, Müller AO, Schmitt K, Blersch KF, Valerius O, Braus GH, Ischebeck T. PUX10 Is a Lipid Droplet-Localized Scaffold Protein That Interacts with CELL DIVISION CYCLE48 and Is Involved in the Degradation of Lipid Droplet Proteins. Plant Cell. 2018 Sep;30(9):2137-2160; https://doi.org/10.1105/tpc.18.00276

    • Hafidh S, Potěšil D, Müller K, Fíla J, Michailidis C, Herrmannová A, Feciková J, Ischebeck T, Valášek LS, Zdráhal Z, Honys D. Dynamics of the Pollen Sequestrome Defined by Subcellular Coupled Omics. Plant Physiol. 2018 Sep;178(1):258-282; https://doi.org/10.1104/pp.18.00648

    • Müller AO, Ischebeck T. Characterization of the enzymatic activity and physiological function of the lipid droplet-associated triacylglycerol lipase AtOBL1. New Phytol. 2018 Feb;217(3):1062-1076; https://doi.org/10.1111/nph.14902

     

    2017

    • Pyc M, Cai Y, Gidda SK, Yurchenko O, Park S, Kretzschmar FK, Ischebeck T, Valerius O, Braus GH, Chapman KD, Dyer JM, Mullen RT. Arabidopsis lipid droplet-associated protein (LDAP) - interacting protein (LDIP) influences lipid droplet size and neutral lipid homeostasis in both leaves and seeds. Plant J. 2017 Dec;92(6):1182-1201; https://doi.org/10.1111/tpj.13754
    • Rotsch AH, Kopka J, Feussner I, Ischebeck T. Central metabolite and sterol profiling divides tobacco male gametophyte development and pollen tube growth into eight metabolic phases. Plant J. 2017 Oct;92(1):129-146; https://doi.org/10.1111/tpj.13633

    • Siegler H, Valerius O, Ischebeck T, Popko J, Tourasse NJ, Vallon O, Khozin-Goldberg I, Braus GH, Feussner I. Analysis of the lipid body proteome of the oleaginous alga Lobosphaera incisa. BMC Plant Biol. 2017 Jun 6;17(1):98; https://doi.org/10.1186/s12870-017-1042-2

    • Reuß DR, Altenbuchner J, Mäder U, Rath H, Ischebeck T, Sappa PK, Thürmer A, Guérin C, Nicolas P, Steil L, Zhu B, Feussner I, Klumpp S, Daniel R, Commichau FM, Völker U, Stülke J. Large-scale reduction of the Bacillus subtilis genome: consequences for the transcriptional network, resource allocation, and metabolism. Genome Res. 2017 Feb;27(2):289-299; https://doi.org/10.1101/gr.215293.116

    • Müller AO, Blersch KF, Gippert AL, Ischebeck T. Tobacco pollen tubes - a fast and easy tool for studying lipid droplet association of plant proteins. Plant J. 2017 Mar;89(5):1055-1064; https://doi.org/10.1111/tpj.13441

    • Rosenberg J, Ischebeck T, Commichau FM. Vitamin B6 metabolism in microbes and approaches for fermentative production. Biotechnol Adv. 2017 Jan-Feb;35(1):31-40; https://doi.org/10.1016/j.biotechadv.2016.11.004

     

    2016

    • Eng F, Haroth S, Feussner K, Meldau D, Rekhter D, Ischebeck T, Brodhun F, Feussner I. Optimized Jasmonic Acid Production by Lasiodiplodia theobromae Reveals Formation of Valuable Plant Secondary Metabolites. PLoS One. 2016 Dec 1;11(12):e0167627; https://doi.org/10.1371/journal.pone.0167627
    • Popko J, Herrfurth C, Feussner K, Ischebeck T, Iven T, Haslam R, Hamilton M, Sayanova O, Napier J, Khozin-Goldberg I, Feussner I. Metabolome Analysis Reveals Betaine Lipids as Major Source for Triglyceride Formation, and the Accumulation of Sedoheptulose during Nitrogen-Starvation of Phaeodactylum tricornutum. PLoS One. 2016 Oct 13;11(10):e0164673; https://doi.org/10.1371/journal.pone.0164673

    • Ischebeck T. Lipids in pollen - They are different. Biochim Biophys Acta. 2016 Sep;1861(9 Pt B):1315-1328; https://doi.org/10.1016/j.bbalip.2016.03.023

    • Hofvander P, Ischebeck T, Turesson H, Kushwaha SK, Feussner I, Carlsson AS, Andersson M. Potato tuber expression of Arabidopsis WRINKLED1 increase triacylglycerol and membrane lipids while affecting central carbohydrate metabolism. Plant Biotechnol J. 2016 Sep;14(9):1883-98; https://doi.org/10.1111/pbi.12550

    • Großhennig S, Ischebeck T, Gibhardt J, Busse J, Feussner I, Stülke J. Hydrogen sulfide is a novel potential virulence factor of Mycoplasma pneumoniae: characterization of the unusual cysteine desulfurase/desulfhydrase HapE. Mol Microbiol. 2016 Apr;100(1):42-54; https://doi.org/10.1111/mmi.13300

    • Heilmann I, Ischebeck T. Male functions and malfunctions: the impact of phosphoinositides on pollen development and pollen tube growth. Plant Reprod. 2016 Jun;29(1-2):3-20; https://doi.org/10.1007/s00497-015-0270-6

     

    2015

    • Steinhorst L, Mähs A, Ischebeck T, Zhang C, Zhang X, Arendt S, Schültke S, Heilmann I, Kudla J. Vacuolar CBL-CIPK12 Ca(2+)-sensor-kinase complexes are required for polarized pollen tube growth. Curr Biol. 2015 Jun 1;25(11):1475-82; https://doi.org/10.1016/j.cub.2015.03.053

    • Stannek L, Thiele MJ, Ischebeck T, Gunka K, Hammer E, Völker U, Commichau FM. Evidence for synergistic control of glutamate biosynthesis by glutamate dehydrogenases and glutamate in Bacillus subtilis. Environ Microbiol. 2015 Sep;17(9):3379-90; https://doi.org/10.1111/1462-2920.12813

     

    2014

    • Bellaire A, Ischebeck T, Staedler Y, Weinhaeuser I, Mair A, Parameswaran S, Ito T, Schönenberger J, Weckwerth W. Metabolism and development - integration of micro computed tomography data and metabolite profiling reveals metabolic reprogramming from floral initiation to silique development. New Phytol. 2014 Apr;202(1):322-335; https://doi.org/10.1111/nph.12631
    • Ischebeck T, Valledor L, Lyon D, Gingl S, Nagler M, Meijón M, Egelhofer V, Weckwerth W. Comprehensive cell-specific protein analysis in early and late pollen development from diploid microsporocytes to pollen tube growth. Mol Cell Proteomics. 2014 Jan;13(1):295-310; https://doi.org/10.1074/mcp.M113.028100