Where do stem cells leave marrow vessels?

© MPI Münster / Gabriele Bixel

In stem cell transplantation, new stem cells are transferred to the recipient’s bloodstream and find their own way to the bone marrow. A research team headed by the CiM group leaders Prof. Ralf Adams and Prof. Dietmar Vestweber identified the blood flow conditions under which blood stem cells migrate from the vessels and can seek a niche in the bone marrow.


Tracking inflammatory processes

© Song et al./Cell Reports

Which molecular mechanisms are at work when, in the case of inflammation, immune cells migrate from the blood vessel into the tissue? Researchers at the Cells-in-Motion Cluster of Excellence have gained new insights into this question. The study has been published in the journal “Cell Reports”.

Cells-in-Motion Cluster of Excellence (CiM)

More than 90 research groups from five faculties at the University of Münster and from the Max Planck Institute of Molecular Biomedicine, are integrated in the Cluster of Excellence. Researchers from the fields of medicine, biology, chemistry and pharmacy, mathematics and computer science, and physics work together to comprehensively investigate cellular behaviour in organisms.

CiM was awarded 33 million euros funding for 5 years. Since 2012, these funds have permitted recruitment of seven new professorships and three new junior research groups, and the establishment of the CiM-IMPRS Graduate School. CiM has been instrumental for the instigation of a unique master's degree course in Experimental Medicine and researchers have undertaken interdisciplinary work in 70 CiM-funded projects.

© CiM - Peter Grewer

Science for the Public

Researchers working at the Cells-in-Motion Cluster of Excellence want to share their fascination with the public and pass on their knowledge in a way that everyone can understand. They do this in the form of events, through multimedia online content and in dialogue with the media.

Dynamic Cells – Dynamic Research

© CiM - Michael Kuhlmann

We will be happy to send you a free copy of the brochure "Cells in Motion – Dynamic Research in the Cluster of Excellence" by post. It gives an overview of CiM's aims and activities and the achievements since the commencement of funding. CiM researchers tell their own personal stories and report on the interactions and projects made possible by CiM. Of course, you will also find all the content here on our website.