Wednesday 20.10.2021

13:00-13:30 Welcome

13:30-17:30 Session: cell & molecular biology

Time Topics and speakers
13:30-14:30 Keynote: The systemic vasculature as guardian of health and longevity
Hellmut Augustin, Vascular Biology and Tumor Angiogenesis, Medical Faculty Mannheim of Heidelberg University, Mannheim, Germany
14:30-15:00 Modeling human brain disorders in vitro with patient-derived induced pluripotent stem cells
Cedric Bardy, Laboratory for Human Neurophysiology and Genetics, South Australian Health and Medical Research Institute, Adelaide, Australia
15:00-15:30 Q&A
15:30-16:00 Heterogeneity of myeloid cells in the brain
Marco Prinz, Institute of Neuropathology, University Hospital Freiburg, Freiburg, Germany
16:00-16:30 Metabolic guidance of vascular growth and differentiation
Michael Potente, Angiogenesis & Metabolism Laboratory, Max Planck Institute for Heart and Lung Research, Bad Nauheim, Germany
16:30-17:00 Young investigator talk: Deciphering the role of Nicastrin in the egress of influenza A virus
Swathi Sukumar, Center for Molecular Biology of Inflammation (ZMBE) Institute of Virology with Prof. Stefan Ludwig, University of Münster, Münster, Germany
17:00-17:30 Q&A

Thursday 21.10.2021

10:00-11:45 Session: cell metabolism 1

Time Topics and speakers
10:00-10:30 Mechanisms of hepatocyte polarization and liver tissue morphogenesis
Marino Zerial, Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany
10:30-11:00 Keeping the good ones: intracellular selection of mitochondrial DNA
Christof Osman, Cell and Developmental Biology, Ludwig-Maximilians-Universität (LMU) Munich, Munich, Germany
11:00-11:30 Young investigator talk: CHIMs - A class of versatile cholesterol analogs with unique properties
Anna Lívia Linard Matos, Center for Molecular Biology of Inflammation (ZMBE) Institute of Medical Biochemistry with Prof. Volker Gerke,  Münster, Germany
11:30-11:45 Q&A

11:45-12:30 Lunch break

12:30-13:00 Poster session

13:00-15:00 Session: cell metabolism 2

Time Topics and speakers
13:00-14:00 Keynote: Molecular architecture as a critical determinant of metabolism
Gökhan S. Hotamisligil, Sabri Ülker Center, Harvard T.H. Chan School of Public Health, Harvard University, Boston, USA
14:00-14:30 The impact of adipose tissues in cancer cells and macrophage immunometabolism
Kelly Grace Magalhães, Laboratory of Immunology and Inflammation, Departament of Cell Biology, University of Brasilia, Brasilia, Brasil
14:30-15:00 Q&A

15:00-19:00 Session: cell architecture visualization

Time Topics and speakers
15:00-16:00 Keynote: Light, CRISPR and DNA repair
Taekjip Ha, Johns Hopkins School of Medicine, Johns Hopkins University, Baltimore, USA
16:00-16:30 Young investigator talk: Potential neuroprotective, immunomodulatory and antiviral effects of omega-3 (DHA) in neuronal and microglial ZIKV infection
Heloísa Antoniella Braz de Melo, Laboratory of Immunology and Inflammation – University of Brasília (UnB)
16:30-17:00 Q&A
17:00-17:30 Cryo-ET reveals sarcomere structures at molecular resolution
Stefan Raunser, Structural Biochemistry, Max Planck Institute of Molecular Physiology, Dortmund, Germany
17:30-18:00 Power at the nanoscale: speed, strength and efficiency in biological motors
Carlos Bustamante, Single Molecule Biophysics, University of California, Berkeley, USA
18:00-18:30 Mechano-genomics of cell-state transitions 
G.V. Shivashankar, Department of Health Sciences and Technology, Swiss Federal Institute of Technology Zurich, Zurich, Switzerland
18:30-19:00 Q&A

Friday 22.10.2021

09:00-12:45 Session: tissue engineering

Time Topics and speakers
09:00-10:00 Keynote: Organoids to model human disease
Hans Clevers, Hubrecht Institute for Developmental Biology and Stem Cell Research, Princess Máxima Center for Pedriatic Oncology, Utrecht, the Netherlands
10:00-10:30 Engineering organoids-on-a-chip
Matthias Lutolf, Laboratory of Stem Cell Bioengineering, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland
10:30-11:00 Q&A
11:00-11:30 Engineering pancreas organogenesis: from self-organization to understanding diabetes
Anne Grapin-Botton, Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany
11:30-12:00 Young investigator talk: The vertebrate RNA-binding protein Dead end controls the access of nanos RNA to ribosome-rich areas at the periphery of germ granules
Kim Westerich, Center for Molecular Biology of Inflammation (ZMBE) Institute of Cell Biology with Prof. Erez Raz Münster, Germany
12:00-12:30 Tissue-specific vascular models – modelling human disease at the microscale
Kristina Haase, Tissue Biology and Disease Modelling, European Molecular Biology Laboratory Barcelona, Barcelona, Spain
12:30-12:45 Q&A

12:45-13:30 Lunch break

13:30-14:00 Poster session

14:00-17:30 Session: systems biology

Time Topics and speakers
14:00-15:00 Keynote: Synthetic biology: life redesigned
James Collins, Massachusetts Institute of Technology, Massachusetts, USA
15:00-15:30 Image analysis and AI in microscopy-based life science research
Carolina Wählby, Department of Information Technology, Uppsala University, Uppsala, Sweden
15:30-16:00 Q&A
16:00-16:30 Towards reconstructing petabyte-scale lightsheet microscopy acquisitions
Stephan Preibisch, Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, USA
16:30-17:00 Computational approaches for analysis of single-cell multi-modal data
Laleh Haghverdi, Computational Methodologies and Omic Analytics, Max Delbrück Center for Molecular Medicine, Berlin, Germany
17:00-17:15 Q&A
17:15-17:30 Closing activities