© GSM Team 2023

17th CiM-IMPRS Interdisciplinary Graduate School Meeting

Cells in Action - Challenging the tango of life
25 October Online, 26th and 27th October Offline, 2023
  • Conference programme

    Wednesday 25.10.2023 (Online)

    9:00-9:10 Welcome Talk

    9:10-10:50 Development and Cell Biology Part I




    Impact of lamin-A/C on cancer progression in vivo
    Katharina Wolf, Radboud University Medical Center, Radboud University, Nijmegen, Netherlands


    A question of dynamics
    Barbara di Ventura, The BIOSS Centre for Biological Signalling Studies, University of Freiburg, Freiburg im Breisgau, Germany


    Q&A and Coffee Break

    10:50-12:50 Vascular Biology


    Guiding Mechanotransduction in Blood Vessels
    Ellie Tzima, Radcliffe Department of Medicine - Cardiovascular Medicine, University of Oxford, Oxford, UK 


    Skeletal stem/progenitor cells: interactions within the bone vascular microenvironment and beyond
    Christa Maes, Skeletal Biology and Engineering Research Center, KU Leuven, Leuven, Belgium


    Leukocyte breaching of blood vessel walls: Insights into the role of pericytes
    Tamara Girbl, Rudolf Virchow Center for Integrative and Translational Bioimaging, University of Würzburg, Würzburg, Germany

    12:50-14:00 Lunch Break

    14:00-15:50 Developmental & Cell Biology Part II


    Membrane repair mechanisms and membrane integrity
    Jesper Nylandsted, Cancer and Inflammation Research Unit, Danish Cancer Society Research Centre, University of Southern Denmark, Copenhagen, Denmark


    Cellular roadmaps: Control of cell architecture by dynamic microtubules
    Anna Akhmanova, Cell Biology, Neurobiology and Biophysics, Department of Biology, Faculty of Science, Utrecht University, Utrecht, The Netherlands


    Q&A and Coffee Break

    15:50-17:50 Immunology & Virology


    Unraveling the Molecular Architecture of the Intestinal Barrier: Insights from Spatial Transcriptomics
    Eduardo Villablanca, Department of Medicine, Karolinska Institute, Stockholm, Sweden


    Circadian control of enteric virus infection
    Julie Pfeiffer, Microbiology department, University of Texas Southwestern Medical Center, Dallas, USA


    Culturing Hepatitis E Virus– recent advances for basic science and drug discovery
    Eike Steinmann, Department of Molecular & Medical Virology, University Bochum, Bochum, Germany

    Thursday 26.10.2023 (In person)

    8:00-8:50 Registration

    8:50-9:00 Welcome Talk




    Young investigator talk: Double-modified AdoMet analogues for selective targeting of methyltransferases
    Mehmet  Erguven, Institute of Biochemistry, WWU Münster, Germany


    Young investigator talk:Two-way Dispatched function in Sonic Hedgehog shedding and transfer to high-density lipoproteins
    Janna Puschmann, University Hospital Münster, Germany 


    Young investigator talk: Unexpected function of the antioxidative xCT system/Slc7a11 in systemic sclerosis
    Jessica Tiemann, University Hospital Münster/ Department of Dermatology, Germany


    Poster Flash Talks


    Q&A and Coffee Break

    10:50-12:00 Non-academic Session


    Career Seminar
    Aishwarya Sundaram, Nature Communications editor, Berlin, Germany

    12:00-13:30 Lunch Break and Poster Session

    13:30-16:30 Systems Biology


    Mitotic rewiring on evolutionary timescales
    Gautam Dey, Cell Biology and Biophysics Unit, EMBL, Heidelberg, Germany


    Cellular regulation in context – Integration of mathematical modeling in time and space with dedicated experiments on different scales
    Edda Klipp, Institute of Biology, Humboldt University of Berlin, Berlin, Germany


    The EGFR/RPTPg sensory morphogenic system: a loop onto itself
    Philippe Bastiaens, Systemic Cell Biology, Max Planck Institute of Molecular Physiology, Dortmund, Germany


    From molecules to life: building living systems from scratch
    Dora Tang, Department of Life Sciences, Saarland University, Saarbrücken, Germany


    Q&A and Coffee Break 

    16:30-17:50  Biophysics Part I


    Liquid–liquid phase separation? Ask the water!
    Martina Havenith-Newen, Center of Molecular Spectroscopy and Simulation of Solvent Controlled Processes, Ruhr University Bochum, Bochum, Germany


    Modulation of the Slo potassium channel by small molecules and auxiliary proteins
    Dr. Tobias Raisch, Structural Biochemistry of Membrane Proteins, Max Planck Institute of Molecular Physiology, Dortmund, Germany

     18:00 onwards  Social Event: Get together & Pub Quiz

    Friday 27.10.2023 (In person)

    9:45-10:00 Registration

    10:00-10:10 Welcome Talk

    10:10-14:40 Neuroscience




    Interactions of Tau protein condensates
    Susanne Wegmann, Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE), Berlin, Germany


    Programming cell fate and age for neuronal disease modeling and repair
    Oliver Brüstle, Institut für Rekonstruktive Neurobiologie, Universitätsklinikum Bonn, Bonn, Germany


    KEYNOTE: Synaptic vesicles – key organelles in synaptic transmission
    Reinhard Jahn, Max Planck Institute for Multidisciplinary Sciences,
    University of Göttingen, Göttingen, Germany

    12:30-14:00 Poster Sessions and Lunch Break


    Single-cell delineation of lineage and genetic identity in the mouse brain
    Christian Mayer, Max Planck Institute for Biological Intelligence, LMU Munich, Martinsried, Munich, Germany

    14:40-16:00 Biophysics Part II


    Cytoskeletal fibres as building blocks for life
    Franziska Lautenschläger, Center for Biophysics, Saarland University, Saarbrücken, Germany


    Cellular cartography: mapping cytoskeletal organization and intracellular transport in neurons
    Lukas Kapitein, Cell Biology, Neurobiology and Biophysics, Department of Biology, Faculty of Science, Utrecht University, Utrecht, The Netherlands

    16:00-16:30 Poster Awards & Closing Ceremony


16th Interdisciplinary Graduate School Meeting

Through the lens of science - Insights into molecular mechanisms
19 October to 21 October, 2022
  • Conference programme

    Wednesday 19.10.2022

    9:00-9:30 Welcome talk

    9:30-12:45 Session: Development and Regeneration

    Time Topics and speakers
    9:30-10:30 KEYNOTE: Coping with mechanical stress: tissue dynamics during development, homeostasis and repair
    Yanlan Mao, Laboratory for Molecular Cell Biology, University College London, London, UK
    10:30-11:00 Deep learning in developmental biology
    Patrick Müller, Chair of Developmental Biology at the University of Konstanz, Konstanz, Germany
    11:00-11:30 Q&A and coffee break

    Young investigator talk: Early endosomes act as local exocytosis hubs to repair endothelial membrane damage
    Nikita Raj, Institute of Medical Biochemistry (ZMBE), WWU Münster, Germany

    12:00-12:30 How to engineer human pluripotent stem cells to understand human development and disease
    Nuria Monteserrat,  Institute of Bioengineering of Catalonia (IBEC), Barcelona, Spain
    12:30-12:45 Q&A

    12:45-13:30 Lunch break

    13:30-16:45 Session: Neurobiology

    13:30-14:30 KEYNOTE: Me and my Markov blanket: Sentience and the Free Energy Principle
    Karl Friston, Institute of Neurology, University College London, London, UK
    14:30-15:00 Mechanisms of Axon Growth and Regeneration
    Frank Bradke, DZNE, Bonn, Germany
    15:00-15:30 Q&A and coffee break
    15:30-16:00 Young investigator talk: Synaptic retrograde regulation of the PKA-induced SNAP-25 and Synapsin-1 phosphorylation
    Aleksandra Polishchuk, Rovira i Virgili University, Spain
    16:00-16:30 The CeNGEN project: neurogenomics at single-cell resolution across an entire nervous system
    Marc Hammarlund, Yale School of Medicine, New Haven, USA
    16:30-16:45 Q&A

    16:45-17:15 Coffee break

    17:45-18:45 Session: Career

    17:45-18:15 Julia Eckhoff, freelance medical writer (Eckcomms Ltd), former Nature Communications editor, London, UK
    18:15-18:45 Michael Spiegelmacher, BionautLabs, Los Angeles, CA, USA

    Thursday 20.10.2022

    9:00-12:15 Session: Vascular Biology

    Time Topics and speakers
    9:00-10:00 KEYNOTE: Neutrophil breaching of venular walls: Novel concepts and pathophysiological regulation
    Sussan Nourshargh, Queen Mary University of London, London, UK
    10:00-10:30 How leukocytes breach the vessel wall: Searching for the ideal transmigration hotspot
    Jaap van Buul, Swammerdam Institute for Life Sciences (SILS) at University of Amsterdam, Amsterdam, the Netherlands
    10:30-11:00 Q&A and coffee break
    11:00-11:30 Young investigator talk: The role of nuclear envelope structure in response to shear stress in Endothelial cells
    Parisa Ghanbari, Department of Vascular Cell Biology, Max Planck Institute for Molecular Biomedicine, Münster, Germany
    11:30-12:00 Young investigator talk: The effect of hydrogen peroxide on the permeability of the blood-brain barrier in vitro
    Margarita Shuvalova, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, RAS, Moscow, Russia
    12:00-12:15 Q&A

    12:15-14:15 Poster and lunch break

    14:15-17:30 Session: Viruses and anti-viral agents

    Time Topics and speakers
    14:15-15:15 KEYNOTE: Synthetic metal complexes for in-cell catalysis
    Peter Sadler, Department of Chemistry, University of Warwick, Coventry, UK
    15:15-15:45 Learning from viruses for EV functionalization
    Kenneth Witwer, John Hopkins University School of Medicine, Baltimore, USA
    15:45-16:15 Q&A and coffee break
    16:15-16:45 Junctional mechanotransduction in angiogenesis
    Stephan Huveneers, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands
    16:45-17:15 SARS-CoV-2 adaptation to effective transmission and its replication in airway epithelia
    Raul Andino, UCSF, San Francisco, USA
    17:15-17:30 Q&A

    Friday 21.10.2022

    9:00-11:00 Session: Computational Biology

    Time Topics and speakers
    9:00-09:30 Generative models of brain function: Inference, mechanisms, and psychedelics
    Adeel Razi, Institute for Brain and Mental Health,  the School of Psychological Sciences, Monash University, Melbourne, Australia
    9:30-10:00 Formatting Biological Big Data to Enable (Personalized) Systems Pharmacology
    Patrick Aloy, Structural Bioinformatics and Network Biology, IRB, Barcelona, Spain
    10:00-10:30 Solving 3D puzzles of biomolecular assemblies by integrative modelling
    Alexandre Bonvin, Bijvoet Center for Biomolecular Research, Utrecht University, Utrecht, Netherlands
    10:30-11:00 Q&A and coffee break

    11:00-16:00 Session: Light for Life

    11:00-11:30 Controlling receptor activity with photoswitchable drugs: basic research and future therapies
    Pau Gorostiza, ICREA, BIST, CIBER, IBEC, Barcelona, Spain
    11:30-12:00 How to Quantify A Zebrafish: Research Software for Image-Driven Biomedical Studies
    Elisabeth Kugler, University College London, London, UK
    12:00-12:15 Q&A
    12:15-14:00 Lunch break & poster session
    14:00-15:00 KEYNOTE: Advanced optical microscopy studies of molecular membrane organizations
    Christian Eggeling, Friedrich-Schiller Universität Jena, Jena, Germany

    Young investigator talk: CryoEM structure of the peroxisomal AAA-complex Pex1/Pex6 processing a substrate
    Maximilian Rüttermann, CryoEM of Complex Nanosystems, Institute for Medical Physics and Biophysics, WWU Münster, Germany

    15:30-16:00 Q&A and coffee break

    16:00-17:15 Session: Lipid Metabolism

    Time Topics and speakers
    16:00-16:30 Lipid transport at contact sites by tube-forming lipid transport proteins
    William Prinz, National Institute of Diabetes and Digestive and Kidney Diseases NIH, Bethesda, Maryland, USA
    16:30-17:00 Dissecting the biophysical phase properties of cellular lipid storage
    Mike Henne, Department of Cell Biology, UTSW Medical Center, UT Southwestern, Dallas, USA
    17:00-17:15 Q&A
    17:15-17:30 Poster awards & Closing ceremony

15th Interdisciplinary Graduate School Meeting

Beyond the Barriers: New Perspectives and Advances in Life Science
20 October to 22 October, 2021
  • Conference programme

    Wednesday 20.10.2021

    13:00-13:30 Welcome

    13:30-17:30 Session: cell & molecular biology

    Time Topics and speakers
    13:30-14:30 Keynote: The systemic vasculature as guardian of health and longevity
    Hellmut Augustin, Vascular Biology and Tumor Angiogenesis, Medical Faculty Mannheim of Heidelberg University, Mannheim, Germany
    14:30-15:00 Modeling human brain disorders in vitro with patient-derived induced pluripotent stem cells
    Cedric Bardy, Laboratory for Human Neurophysiology and Genetics, South Australian Health and Medical Research Institute, Adelaide, Australia
    15:00-15:30 Q&A
    15:30-16:00 Heterogeneity of myeloid cells in the brain
    Marco Prinz, Institute of Neuropathology, University Hospital Freiburg, Freiburg, Germany
    16:00-16:30 Metabolic guidance of vascular growth and differentiation
    Michael Potente, Angiogenesis & Metabolism Laboratory, Max Planck Institute for Heart and Lung Research, Bad Nauheim, Germany
    16:30-17:00 Young investigator talk: Deciphering the role of Nicastrin in the egress of influenza A virus
    Swathi Sukumar, Center for Molecular Biology of Inflammation (ZMBE) Institute of Virology with Prof. Stefan Ludwig, University of Münster, Münster, Germany
    17:00-17:30 Q&A

    Thursday 21.10.2021

    10:00-11:45 Session: cell metabolism 1

    Time Topics and speakers
    10:00-10:30 Mechanisms of hepatocyte polarization and liver tissue morphogenesis
    Marino Zerial, Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany
    10:30-11:00 Keeping the good ones: intracellular selection of mitochondrial DNA
    Christof Osman, Cell and Developmental Biology, Ludwig-Maximilians-Universität (LMU) Munich, Munich, Germany
    11:00-11:30 Young investigator talk: CHIMs - A class of versatile cholesterol analogs with unique properties
    Anna Lívia Linard Matos, Center for Molecular Biology of Inflammation (ZMBE) Institute of Medical Biochemistry with Prof. Volker Gerke,  Münster, Germany
    11:30-11:45 Q&A

    11:45-12:30 Lunch break

    12:30-13:00 Poster session

    13:00-15:00 Session: cell metabolism 2

    Time Topics and speakers
    13:00-14:00 Keynote: Molecular architecture as a critical determinant of metabolism
    Gökhan S. Hotamisligil, Sabri Ülker Center, Harvard T.H. Chan School of Public Health, Harvard University, Boston, USA
    14:00-14:30 The impact of adipose tissues in cancer cells and macrophage immunometabolism
    Kelly Grace Magalhães, Laboratory of Immunology and Inflammation, Departament of Cell Biology, University of Brasilia, Brasilia, Brasil
    14:30-15:00 Q&A

    15:00-19:00 Session: cell architecture visualization

    Time Topics and speakers
    15:00-16:00 Keynote: Light, CRISPR and DNA repair
    Taekjip Ha, Johns Hopkins School of Medicine, Johns Hopkins University, Baltimore, USA
    16:00-16:30 Young investigator talk: Potential neuroprotective, immunomodulatory and antiviral effects of omega-3 (DHA) in neuronal and microglial ZIKV infection
    Heloísa Antoniella Braz de Melo, Laboratory of Immunology and Inflammation – University of Brasília (UnB)
    16:30-17:00 Q&A
    17:00-17:30 Cryo-ET reveals sarcomere structures at molecular resolution
    Stefan Raunser, Structural Biochemistry, Max Planck Institute of Molecular Physiology, Dortmund, Germany
    17:30-18:00 Power at the nanoscale: speed, strength and efficiency in biological motors
    Carlos Bustamante, Single Molecule Biophysics, University of California, Berkeley, USA
    18:00-18:30 Mechano-genomics of cell-state transitions 
    G.V. Shivashankar, Department of Health Sciences and Technology, Swiss Federal Institute of Technology Zurich, Zurich, Switzerland
    18:30-19:00 Q&A

    Friday 22.10.2021

    09:00-12:45 Session: tissue engineering

    Time Topics and speakers
    09:00-10:00 Keynote: Organoids to model human disease
    Hans Clevers, Hubrecht Institute for Developmental Biology and Stem Cell Research, Princess Máxima Center for Pedriatic Oncology, Utrecht, the Netherlands
    10:00-10:30 Engineering organoids-on-a-chip
    Matthias Lutolf, Laboratory of Stem Cell Bioengineering, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland
    10:30-11:00 Q&A
    11:00-11:30 Engineering pancreas organogenesis: from self-organization to understanding diabetes
    Anne Grapin-Botton, Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany
    11:30-12:00 Young investigator talk: The vertebrate RNA-binding protein Dead end controls the access of nanos RNA to ribosome-rich areas at the periphery of germ granules
    Kim Westerich, Center for Molecular Biology of Inflammation (ZMBE) Institute of Cell Biology with Prof. Erez Raz Münster, Germany
    12:00-12:30 Tissue-specific vascular models – modelling human disease at the microscale
    Kristina Haase, Tissue Biology and Disease Modelling, European Molecular Biology Laboratory Barcelona, Barcelona, Spain
    12:30-12:45 Q&A

    12:45-13:30 Lunch break

    13:30-14:00 Poster session

    14:00-17:30 Session: systems biology

    Time Topics and speakers
    14:00-15:00 Keynote: Synthetic biology: life redesigned
    James Collins, Massachusetts Institute of Technology, Massachusetts, USA
    15:00-15:30 Image analysis and AI in microscopy-based life science research
    Carolina Wählby, Department of Information Technology, Uppsala University, Uppsala, Sweden
    15:30-16:00 Q&A
    16:00-16:30 Towards reconstructing petabyte-scale lightsheet microscopy acquisitions
    Stephan Preibisch, Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, USA
    16:30-17:00 Computational approaches for analysis of single-cell multi-modal data
    Laleh Haghverdi, Computational Methodologies and Omic Analytics, Max Delbrück Center for Molecular Medicine, Berlin, Germany
    17:00-17:15 Q&A
    17:15-17:30 Closing activities

14th Interdisciplinary Graduate School Meeting

Breaking the Frontiers: Modern Perspectives in Life Science
30 September to 2 October, 2020
  • Conference programme

    Wednesday 30.09.2020

    14:00-14:30 Welcome

    14:30-19:00 Session 1 – Biology

    Time Topics and speakers
    14:30-15:30 Keynote: Molecular Mechanism of Cytokinesis
    Prof. Thomas D. Pollard, Department of Molecular Cellular and Developmental Biology, Yale University, USA
    15:30-16:00 Blastoids – Blastocyst-like Structures Generated Solely From Stem Cells
    Dr. Nicolas Rivron, Austrian Academy of Sciences, IMBA - Institute of Molecular Biotechnology, Austria
    16:00-16:30 Q&A Session & Coffee Break
    16:30-17:00 Dynamizing Nuclear Actin Filaments in Cell Division
    Prof. Robert Grosse, Experimental and clinical pharmacology and toxicology, Freiburg University, Germany
    17:00-17:30 Young Investigator Talk: Excluding Oct4 From Yamanaka Cocktail Unleashes the Developmental Potential of iPSCs
    Sergiy Velychko from Professor Dr. Hans R. Schöler's lab, Max Planck Institute for Molecular Biomedicine, Germany
    17:30-18:00 Identifying Chromatin Regulators at Specific Genomic Loci
    Prof. Sylvia Erhardt, Center for Molecular Biology, Heidelberg University, Germany
    18:00-18:30 Q&A Session
    18:30-19:00 Closing Remarks for the Day

    Thursday 01.10.2020

    09:00-13:00 Session 2 – Biology

    Time Topics and speakers
    09:00-10:00 Keynote: The Vascular Barrier – What We Know and Why It’s Important
    Prof. Lena Claesson-Welsh, Vascular Biology, Uppsala University, Sweden
    10:00-10:30 Quantifying Material Properties of Living Matter and How These Relate to Biological Function
    Prof. Lene B Oddershede, Optical Tweezers Group, Niels Bohr Institute, University of Copenhagen, Denmark
    10:30-11:00 Q&A Session & Coffee Break
    11:00-11:30 Young Investigator Talk: Master Mitotic Kinases Regulate HPV16 Nuclear Delivery During Mitosis
    Matteo Rizzato from Prof. Dr. Mario Schelhaas's lab, Institute for Cellular Virology, Münster University, Germany
    11:00-11:30 Young Investigator Talk: Master Mitotic Kinases Regulate HPV16 Nuclear Delivery During Mitosis
    Matteo Rizzato from Prof. Dr. Mario Schelhaas's lab, Institute for Cellular Virology, Münster University, Germany
    11:30-12:00 Young Investigator Talk: PECAM-1 Mediates Leukocyte Diapedesis by Triggering Dephosphorylation of VE-Cadherin-Y731
    Nida Arif from Prof. Dr. Dietmar Vestweber's lab, Max Planck Institute for Molecular Biomedicine, Germany
    12:00-12:30 Tolerance to Aneuploidy
    Prof. René Medema, Cell division and Cancer, Netherlands Cancer Institute, Netherlands
    12:30-13:00 Q&A Session

    13:00-14:00 Lunch Break

    14:00-19:00 Session 3 – Biophysics

    Time Topics and speakers
    14:00-15:00 Keynote: Engineering 3D Cultures of Physiology and Disease – How Simple is Complex Enough?
    Prof. Christopher Chen, Tissue Microfabrication Lab, Boston University & Harvard University, USA
    15:00-15:30 Young Investigator Talk: Synthetic Extracellular Matrices With Tailored Properties Support Lumen Formation During Angiogenic Sprouting
    Jifeng Liu from Dr. Britta Trappmann's lab, Max Planck Institute for Molecular Biomedicine, Germany
    15:30-16:00 Active Cell Deformation Through Actin Assembly, and How We May Infer Nucleus Deformation
    Dr. Cécile Sykes, Institute Curie PSL Paris, Sorbonne University, France
    16:00-17:00 Coffee Break & Poster Session
    17:00-17:30 Intravascular Tracking of Tumor Metastasis
    Dr. Jacky Goetz, Lab for Tumor Biomechanics, INSERM Institut d’Hématologie et d’Immunologie Strasbourg, France
    17:30-18:00 Deep Learning-Based Point-Scanning Super-Resolution Microscopy
    Prof. Uri Manor, Biophotonics Core Facility, Salk Institute for Biological Studies, USA
    18:00-18:30 Q&A Session
    18:30-19:00 Closing Remarks for the Day

    Friday 02.10.2020

    10:00-13:00 Session 4 – Biochemistry

    Time Topics and speakers
    10:00-11:00 Keynote: Synthetic Protobiology – The Chemistry of Life-like Objects
    Prof. Stephen Mann, Bristol Centre for Functional Nanomaterials, University of Bristol, UK
    11:00-11:30 Spatiotemporal Control Over Adhesions in Synthetic Cells Using Light
    Prof. Seraphine Wegner, Institute for Physiological Chemistry and Pathobiochemistry, Münster University, Germany
    11:30-12:00 Phthalocyanine-Based Photosensitizers and Their (Soft) Nanostructures for Photo-Antimicrobial Applications
    Dr. Anzhela Galstyan, Center for Soft Nanoscience, Münster University, Germany
    12:00-12:30 Molecularly Engineered Nanobiomaterials to Understand and Control Biology
    Dr. Helena Azevedo, School of Engineering and Materials Science and Institute of Bioengineering, Queen Mary University of London, UK
    12:30-13:00 Q&A Session

    13:00-14:00 Lunch Break

    14:00-16:30 Session 5 – Bioinformatics/Mathematics

    Time Topics and speakers
    14:00-14:30 Prediction and Design of Biological Sequences with Neural Machines
    Prof. Debora Marks, Department of Systems Biology, Harvard Medical School, USA
    14:30-15:00 Modeling Cellular Response in Time and Space
    Prof. Fabian Theis, Institute of Computational Biology, Helmholtz Zentrum München, Germany
    15:00-15:30 Suggestions From Mathematics for the Functioning of Flatworm Regeneration
    Prof. Angela Stevens, Institute for Applied Mathematics: Analysis and Numerics, Münster University, Germany
    15:30-16:00 Q&A Session
    16:00-16:30 Final Closing Remarks


  • Speakers

    • Prof. Thomas D. Pollard’s research focuses on understanding cell motility through the study of actin filaments and myosin motors. His lab uses a combination of biochemistry, biophysics, microscopy and fission yeast genetics to investigate the molecular basis of cellular motility and cytokinesis.
    • Dr. Nicolas Rivron’s lab is seeking to understand the general principles underlying the organization of stem cells in the early developmental phase of organisms. To study these principles, they use model organisms (Blastoids) that were created by harnessing the intrinsic potential of stem cells to self-organize which allows to systematically modulate and analyse their behavior. Their main focus is to generate more such embryo models for drug and genetic screens, biochemistry and genomic analysis.
    • Prof. Robert Grosse investigates the role of cytoskeletal proteins such as formin in cell motility, tumor progression and metastasis. His lab is also interested in discovering how actin network formation and organization drives cellular behaviors, such as polarization, invasion, mitotic spindle formation, chromosome congression and the effect of intracellular signaling on cellular morphology and dynamics.
    • Prof. Sylvia Erhardt’s research focuses on understanding the epigenetic mechanisms specifying centromere identity and aims to elucidate how these mechanisms are linked to chromosome segregation and cell cycle progression.
    • Prof. Lena Claesson-Welsh’s research focus lies in the molecular mechanisms of endothelial cell biology, particularly angiogenesis and its link to cancer metastasis, VEGF signal transduction, vessel permeability and tissue homeostasis.
    • Prof. Lene B Oddershede’s lab investigates physical properties of biological systems at levels ranging from the single molecule to the whole cell with a particular interest in stem cells. Her lab uses single particle tracking, fluorescence, sub-diffraction techniques and their state-of-the-art force-scope optical tweezers to study nanoparticle plasmonics.
    • Dr. Alex Bird’s group investigates the function and regulation of microtubule networks in context to mitosis, migration and neuritogenesis. One of the major aims of his research is to uncover the regulatory mechanisms and pathways that guide the formation function of the mitotic spindle to ensure genome stability.
    • Prof. René Medema studies the molecular mechanisms of cell division. His lab works on understanding cell recovery from DNA damage and aims to use this knowledge in designing efficient anti-cancer drugs. They are also interested in studying the role of establishment of the correct balance of forces during bipolar spindle assembly, which is required to segregate chromosomes during cell division.
    • Prof. Christopher Chen is interested in cellular interactions, especially the cooperation between mechanical and biochemical signaling in the regulation of angiogenesis and stem cell biology. His lab studies tissue vascularization, connective tissues and cancer using micro- and nanofabrication tools.
    • Prof. Cécile Sykes studies Biomimetism of cell movement and approaches the biological problems using the principles of soft matter physics. Her team focuses mainly on the underlying mechanisms of cell division and motility that would expand the knowledge about cancer invasion and metastasis. With a combination of in-vitro biomimetic systems and in-vivo cellular and animal models ranging from nematode worms to mouse oocytes, her research provides answers to many physical and biochemical mechanisms governing cell shape change and movement.
    • Having developed the unique intravital CLEM (Correlative Light and Electron Microscopy) technology, Dr. Jacky Goetz’s lab tracks intravascular tumor metastasis and are keen on understanding the molecular and cellular mechanisms driving metastasis formation. They are also examining the role of mechanical forces in tumor invasion and the fate and function of tumor exosomes on local and distant microenvironment during the priming of metastatic niches.
    • The primary focus of Prof. Uri Manor is the integration and application of optical and charged particle detection technologies to investigate problems of critical biological significance. He is focused on developing deep learning-based computational approaches to increase the resolution, sensitivity and speed of next generation microscopes, as well as designing nanoprobes for high spatiotemporal resolution imaging of subcellular dynamics. His main biological interests are organelle-organelle contacts, cytoskeletal dynamics, mitochondria, sensorineural hearing loss and neurodegeneration.
    • Prof. Stephen Mann is the founder of biomimetic chemistry and is distinguished for his contributions to biomineralization, bioinspired materials chemistry, self-assembly of functional nanostructures and hybrid nanoscale objects. His current research focus includes, the chemical synthesis, characterization and emergence of complex organized matter, including models of protocell assembly.
    • Prof. Seraphine Wegner is interested in light-controlled systems, especially the spatiotemporal control of cell-material and cell-cell interactions and associated processes in natural and synthetic minimal cells by using visible light. Her lab focuses on addressing questions in cell biology to better engineer new synthetic minimal cells, which reduces the complexity despite retaining the key features of a cell, allowing to quantify and correlate cell behavior with their molecular information.
    • Dr. Helena Azevedo engineers molecules for biomedical application. She uses supramolecular chemistry to program macromolecules to self-assemble into biologically active structures to understand the energy pathways required for this self-assembly.
    • Prof. Debora Marks and her lab develop computational methods for interpreting genetic variation with a focus on biomedical applications. To this end they have developed tools to predict 3D structures of RNAs, RNA-protein complexes and proteins from genomic sequence data. The current focus of her lab lies in developing methods in deep learning to address a wide range of biological challenges including the prediction of the effects of genetic variation and sequence design for biosynthetic applications.
    • The research focus of Prof. Fabian Theis’s lab includes using computational methods for analyzing and modelling single cell heterogeneities with a focus on machine learning approaches and predictive algorithms applied to biological and biomedical questions. This includes the development of tools for scRNA-Seq Analysis, predicting perturbation effects in scRNA-Seq data and analysing and interpreting RNA Velocity.
    • Prof. Angela Stevens is particularly interested in mathematical modelling in biology and medicine, where she analyses developmental processes and cell motility. Her work combines rigorous mathematical research with challenging problems in the life sciences.

13th Interdisciplinary Graduate School Meeting

Horizons in biology: beyond the biological borders
Münster, 24–26 April 2019


  • Conference programme

    Wednesday, 24.04.2019

    09:00 Registration
    11:30 Lunch
    12:15 Opening remarks

    Morphogenesis session

    12:30 Keynote: Phase segregation of ooplasm and yolk granules in zebrafish oocytes is mediated
    by periodic bulk actin polymerization waves
    Carl-Philipp Heisenberg, Klosterneuburg/Austria
    13:30 Imaging How Cells Choose their Fate, Shape and Position to Form the
    Mammalian Embryo
    Nicolas Plachta, Singapore
    14:10 Coffee break

    Morphogenesis session

    14:40 Connections for vision
    Iris Salecker, London/UK
    15:20 Investigating neuronal cell fate in vivo in the developing vertebrate retina
    Leanne Godinho, Munich/Germany

    Poster session

    16:00 Students will present their projects in form of posters.

    Chemistry session

    17:00 DNA origami tools to explore biological processes
    Barbara Sacca, Essen/Germany

    Evening Program

    18:45 Dinner and city tour

    Thursday, 25.04.2019

    Cell biology session

    9:00 Frank Edenhofer, Innsbruck/Austria
    9:40 Binding of surface-associated antigen causes plasma membrane wounding
    and repair in B lymphocytes, a process that promotes BCR activation
    Norma Andrews, College Park/USA
    10:20 The Impact of organelle size control on a physiological function: Weibel-Palade Bodies and
    Daniel Cutler, London/UK
    11:00 Coffee break

    Cell biology session

    11:30 Information content of intracellular patterns
    Wu Min, Singapore
    12:10 Molecular control of actomyosin contractility and morphogenesis in epithelia
    Andreas Wodarz, Cologne/Germany
    12:50 Lunch

    Cell dynamics session

    13:50 The conserved Myosin 1D controls multiscale chirality in Drosophila
    Stephane Noselli, Nice/France
    14:30 Leukocyte transendothelial migration: the endothelium in control
    Jaap van Buul, Amsterdam/Netherlands
    15:10 Dynamics and mechanics of collective cancer cell migration
    Andrew Clark, Paris/France
    15:50 Coffee break

    Cell dynamics & biophysics session

    16:20 Keynote: Mechanosensing Depletion Drives Regeneration and Cancer
    Michael Sheetz, Singapore
    17:20 Mechanosensitivity and microtubule-dependent regulation of integrin-mediated adhesions
    Alexander D. Bershadsky, Singapore
    18:00 Reconstitution of the steady state of dynamic actin networks
    Laurent Blanchoin, Grenoble/France
    18:40 Physics of epithelial flows and folds
    Guillaume Salbreux, London/UK

    Evening Program

    20:15 Social event

    Friday, 26.04.2019

    Chemistry session

    8:20 Regulation of lipid droplet - endoplasmic reticulum membrane contacts by seipin
    Elina Ikonen, Helsinki/Finland

    Genomics session

    9:00 Mass spectrometry for cell signaling: from global maps to new biological insights
    Chuna Ram Choudhary, Copenhagen/Denmark
    9:40 Christoph Lippert, Berlin/Germany
    10:20 Keynote: Tracing genomic regulatory programs at single-cell resolution
    Stein Aerts, Leuven/Belgium

    Poster session

    11:20 Students will present their projects in form of posters.

    Young investigator's session

    12:20 Simulating the binding of Pioneer Transcription Factors to the nucleosome
    Jan Huertas, University of Münster/Max-Planck Institute for Molecular Biomedicine
    12:40 Cell surface functionality is triggered by endolysosomal calcium release
    Nicole Heitzig, University of Münster/Institute of Medical Biochemistry
    13:00 Endothelial Basement Membrane Laminins Affect Shear Response in Resistance Arteries by Modulating Communication between Endothelium and Smooth Muscle
    Anna-Liisa Luik, University of Münster/Institute for Physiological Chemistry and Pathobiochemistry
    13:20 Novel routes to holey (carbon) support films
    Philipp Selenschik, University of Münster/Institute of Medical Physics and Biophysics

    Closing ceremony

    13:40 Closing remarks and poster awards
    13:50 Lunch


© CiM

12th Interdisciplinary Graduate School Meeting

From molecules to life: a multiscale perspective of cell cynamics
Münster, 25–27 April 2018


  • Conference programme

    Wednesday, 25.04.2018

    09:00 Registration
    13:00 Opening

    Session 1: Cytoskeleton

    13:15 Reconstitution of (parts of) cell division
    Andrea Musacchio, Dortmund - Germany
    13:55 Comparative approach to understanding mitotic division
    Snezhana Oliferenko, London - UK
    14:35 Coffee break

    Session 2: Cell trafficking

    15:05 T-/B-cell interaction promoting CNS autoimmunity
    Alexander Flügel, Göttingen - Germany
    15:45 VE-cadherin endocytosis regulates cell polarity, collective cell migration, and angiogenesis during development
    Andrew P. Kowalczyk, Atlanta - USA

    Poster Session

    16:25 Students will present their projects in form of posters.

    Session 3: Ion channels

    17:25 Open Sesame...Close Sesame: Ion Channels - Key to stomatal gating
    Kavitha Sankaranarayanan, Chennai - India
    18:05 Structure and Biology of NMDA receptors
    Hiro Furukawa, New York - USA

    Evening Program

    18:45 Dinner and social event

    Thursday, 26.04.2018

    Session 4: Biomechanics

    09:20  Cell mechanoadaptation and tissue stiffening in health and disease
    Miguel Ángel del Pozo, Madrid - Spain
    10:00  Structural organisation, liquid disorder, jamming, and glassy dynamics in king penguin colonies
    Ben Fabry, Erlangen - Germany
    10:40  Real-time deformability cytometry: Mechanical phenotyping for translational applications
    Fabian Czerwinski, Greifswald - Germany
    11:20  Coffee break

    Session 5: Biochemistry

    11:50  Protein TAILS Tell Remarkable Tales: Proteomic Untangling of the Protease Web in Immunity
    Christopher Overall, Vancouver - Canada
    12:30 Circadian rhythms in immune cell trafficking and function
    Christoph Scheiermann, Munich - Germany

    Session 6: Chemistry

    14:10 Allosteric inhibitors of flaviviral NS3/NS2B proteases
    Tanja Schirmeister, Mainz - Germany
    14:50 The molecular dynamics of potassium channel permeation, selectivity and gating
    Bert de Groot, Göttingen - Germany
    15:30 Young investigator talk
    Imtiaz Ali

    Poster Session

    15:50 Students will present their projects in form of posters.

    Session 7: RNA and DNA biology

    16:50 Simulating chromatin
    Modesto Orozco, Barcelona - Spain
    17:30 Sensing the environment through tRNA modifications: T. brucei dynamically alters Queuosine levels in response to nutrient changes
    Juan Alfonzo, Columbus - USA
    18:10 Young investigator talk
    Sergiy Velychko

    Evening Program

    18:30 City tour and dinner (for speakers only)

    Friday, 27.04.2018

    Session 8: Imaging

    09:00 Collective cancer cell invasion: plasticity and interconversions
    Peter Friedl, Nijmegen - The Netherlands
    10:00 Endocytic control of mechanics, collective motion and cancer progression
    Giorgio Scita, Milan - Italy
    10:40 Coffee break

    Session 9: Imaging

    11:10 Actin regulation in healthy and diseased brain
    Pirta Hotulainen, Helsinki - Finland

    Closing Ceremony

    11:50 Closing remarks and poster awards

    Career Talks & Workshop

    13:20 Career talk
    14:30 Workshop: Huygens post-processing: the fastest road to TRUE analysis of your microscopic data
    16:30 End



11th Interdisciplinary Graduate School Meeting

From cells to organisms: insights into biomolecular mechanisms
Münster, 26–28 April 2017


  • Conference programme

    Wednesday, 26.04.2017

    10:00 Registration
    12:00 Lunch (for speakers only)
    12:45 Opening remarks

    Session 1: Vasculature

    13:00  Endothelial cells in motion
    Holger Gerhardt, Berlin - Germany
    13:40  Vascular malformations: From human genetic mosaicism towards clinical trials
    Miikka Vikkula, Brussels - Belgium
    14:20  Cell mechanoadaptation: Caveolae mechanobiology and tissue biomechanics
    Miguel Ángel del Pozo Barriuso, Madrid - Spain
    15:00 Coffee break

    Session 2: Physiology

    15:30 How to use atomic-scale manipulations to study function & pharmacology of ion channels
    Stephan Pless, Copenhagen - Denmark
    16:10  The Quantum Robin: Magnetoreception in migratory birds
    Henrik Mouritsen, Oldenburg - Germany
    16:50  Optical control of synaptic signaling proteins: Photoswitchable ligands to study the function of glutamate receptors
    Andreas Reiner, Bochum - Germany

    Evening Program

    18:45 City tour and dinner (for speakers only)

    Thursday, 27.04.2017

    Session 3: Imaging and Detection Tools

    09:00  Labeling proteins on-demand with fl uorogenic probes
    Arnaud Gautier, Paris - France
    09:40  Bioelectronics: Building connections between DNA, proteins, neurons and electronics
    Andreas Offenhäusser, Jülich - Germany
    10:20  Molecular tracers for neuroinfl ammation: From synthesis to animal imaging
    Andrew Sutherland, Glasgow - UK
    11:00  Coffee break

    Session 4: Cell Migration

    11:30  Dynamic interplay between mitochondria, ER and actin filaments during mitochondrial fission
    Henry Higgs, Dartmouth - USA
    12:10 Rho GTPases: signalling in cell adhesion and migration
    Anne Ridley, London - UK
    12:50 Studying the mechanics and molecules underlying in vivo tissue invasion
    Daria Siekhaus, Klosterneuburg - Austria
    13:30 Lunch (for speakers only)

    Session 5: Biophysics

    14:30 Synthetic morphogenesis in naïve embryonic tissues
    Stefano De Renzis, Heidelberg - Germany
    15:10 A new perspective on nanoscale structure and dynamics with ultrasensitive optical microscopy
    Philipp Kukura, Oxford - UK
    15:50 From ancient lipids to synthetic life
    James Sáenz, Dresden - Germany

    Poster Session

    16:45 Students present their projects in a form of poster.

    Evening Program

    18:30 Dinner
    19:30 Social event

    Friday, 28.04.2017

    Session 6: Dynamics of the Cytoskeleton

    09:30 Forces controlling endothelial adhesion dynamics within the vasculature
    Stephan Huveneers, Amsterdam - Netherlands
    10:10 Cellular level chemotaxis and haptotaxis
    Nikolaos Sfakianakis, Mainz - Germany
    10:50 Molecular mechanisms for making tubes: anisotropies and cytoskeletal crosstalk
    Katja Röper, Cambridge - UK
    11:30 Lunch (for speakers only)

    Career Talks

    12:30 The industrial path: Insights into industrial careers
    13:00 The academical path: overview of grant application procedures and the career path

    Closing Remarks

    13:30 Closing remarks and poster awards


10th Interdisciplinary Graduate School Meeting

Insights into molecular and cellular dynamics
Münster, 11-13 May 2016


  • Conference programme

    Wednesday, 11.05.2016

    9:00 Registration
    10:45 Welcome Remarks

    Session 1: Immunology

    11:00  NETs - the second function of chromatin
    Arturo Zychlinsky (Max Planck Institute for Infection Biology)
    11:30  Retroviruses, envelopes, receptors and metabolic markers
    Marc Sitbon (The Institute of Molecular Genetics of Montpellier)
    12:00  Mammalian sterile 20-like kinase 1: an important player for neutrophil transmigration
    Markus Sperandio (Ludwig-Maximilians-Universität Munich)
    12:30 Lunch

    Session 2: Cell Biology

    14:00 Establishing new tools for manipulating alternative model organisms in the study of the evolution of developmental processes
    Cassandra G. Extavour (Department of Molecular and Cellular Biology, Harvard University)
    14:30  Extracellular matrix and its role in biomedical research
    Katja Schenke-Layland (Fraunhofer Institute for Interfacial Engineering and Biotechnology)
    15:00  Deconstructing cell migration
    Matthieu Piel (Institut Curie)
    15:30  Innate immune cell dynamics at sites of inflammation and infection
    Tim Lämmermann (Max Planck Institute of Immunobiology and Epigenetics)
    16:00 Coffee break

    Session 3: Young Scientist Talks

    16:30 Wound-induced signals and positional cues cooperate to initiate regeneration in the planarian s. mediterranea
    Suthira Owlarn (Münster, Germany)
    16:50 Regulation of bone vascularization and osteogenesis during mouse development
    Urs H. Langen (Münster, Germany)
    17:10 A nanotechnological approach reveals the role of alpha 2 beta 1 integrin in collagen-induced platelet aggregation
    Augusto Martins Lima (Münster, Germany)
    17:30 Plasma membrane organization in zebrafish primordial germ cells (PGCs) bleb
    Mohammad Goudarzi (Münster, Germany)

    Evening Program

    18:30 Guided City Tour
    19:30 Dinner

    Thursday, 12.05.2016

    Session 4: Developmental Biology

    09:00  Regeneration of hematopoietic stem cells from endothelial cells
    Dhvanit Shah (Harvard Medical School)
    09:30  Notch regulates BMP responsiveness and lateral branching in vessel networks via SMAD6
    Victoria L. Bautch (University of North Carolina at Chapel Hill)
    10:00  Molecular regulation of endothelial barrier properties in the central nervous system
    Stefan Liebner (Goethe University Frankfurt)
    10:30  CNS neuronal progenitors regulate vascular patterning in adjacent mesodermal tissues
    Didier Stainier (Max Planck Institute for Heart and Lung Research)
    11:00 Coffee break

    Keynote lecture

    11:30  The development of colour patterns in fishes - Towards an understanding of the evolution of beauty
    Christiane Nüsslein-Volhard (Max Planck Institute for Developmental Biology)
    12:30 Lunch

    Session 5: Applied Mathematics

    14:00 Aspects of cell swimming motility
    Eamonn Gaffney (University of Oxford)
    14:30 Mathematical modeling of mechano-chemical pattern formation
    Anna Marciniak-Czochra (University of Heidelberg)
    15:00 Identification of mammary stem cells and their dynamics during branching morphogenesis
    Edouard Hannezo (University of Cambridge)
    15:30 Coffee break

    Poster Session

    16:00 to 18:00

    Evening Program

    18:30 Dinner
    19:30 Party

    Friday, 13.05.2016

    Session 6: Genomics and Systems Biology

    09:00 Towards a true isoform biology: deep long read sequencing reveals molecular co-association of distant splicing events in the human brain
    Hagen Tilgner (Stanford University)
    09:30 Epigenomic establishment of macrophage tolerance and trained immunity
    Henk Stunnenberg (Radboud Institute for Molecular Life Sciences)
    10:00 Establishment and maintenance of mammalian heterochromatin
    Thomas Jenuwein (Max Planck Institute of Immunobiology and Epigenetics)
    10:30 Coffee break

    Session 7: Drug Design

    11:00 Controlling biological activity with photopharmacology
    Dirk Trauner (Ludwig-Maximilians-Universität Munich)
    11:30 Tools to probe the epigenetic code
    Manfred Jung (University of Freiburg)
    12:00 Highly selective JAK3-inhibitors with a covalent-reversible binding mode targeting a nitrile induced arginine pocket
    Stefan Laufer (University of Tübingen)
    12:30 Lunch

    Session 8: Neuroscience

    14:00 Large protein and nanoparticle transport across the blood-brain barrier (BBB),with implications for drug delivery
    N. Joan Abbott (King's College London)
    14:30 Glial glycogen and brain energy metabolism: new insights
    Bruce R. Ransom (University of Washington)
    15:00 The interaction of genes and epigenes – A chromatin loop conferring an increased risk to develop Alzheimer’s disease
    Johannes Gräff (École polytechnique fédérale de Lausanne)


    15:30 Closing remarks and poster prize