Michael Holtkamp
© Michael Holtkamp
Michael Holtkamp
Laboratory Chemist
Room W 107
Corrensstraße 28
48149 Münster
T: +49 (251) 83-33176


Laboratory chemist in the Karst group


  • Sample preparation
  • Elemental analysis
  • Total reflection X-ray fluorescence (TXRF)
  • Mikro X-ray fluorescence (µXRF)
  • Laser ablation (LA)
  • Inductively coupled plasma with optical emission spectrometry (ICP-OES)
  • Inductively coupled plasma with mass spectrometry (ICP-MS)
  • Atomic absorbance spectrometry (AAS)

ResearcherID: B-2159-2017



  • Buchholz R, Krossa S, Andersen MK, Holtkamp M, Sperling M, Karst U, Tessem MB. . ‘A simple preparation protocol for shipping and storage of tissue sections for laser ablation-inductively coupled plasma-mass spectrometry imaging.’ Metallomics 14, No. 3: mfac013. doi: 10.1093/mtomcs/mfac013.

  • Lützen E, Holtkamp M, Stamme I, Schmid R, Sperling M, Pütz M, Karst U. . ‘Multimodal imaging of hallucinogens 25C- and 25I-NBOMe on blotter papers.’ Drug Testing and Analysis 12: 465–471. doi: 10.1002/dta.2751.
  • Beil SB, Breiner M, Schulz L, Schüll A, Müller T, Schollmeyer D, Bomm A, Holtkamp M, Karst U, Schade W, Waldvogel SR. . ‘About the selectivity and reactivity of active nickelelectrodes in C–C coupling reactions.’ RSC Advances 10, No. 24: 14249–14253. doi: 10.1039/d0ra02673e. [online first]

  • Raman SP, Keil C, Dieringer P, Hubner C, Bueno A, Gurikov P, Nissen J, Holtkamp M, Karst U, Haase H. . ‘Alginate aerogels carrying calcium, zinc and silver cations for wound care: Fabrication and metal detection.’ Journal of Supercritical Fluids 153: 104545. doi: 10.1016/j.superflu.2019.104545.

  • Gütz C., Grimaudo V., Holtkamp M., Hartmer M., Werra J., Frensemeier L., Kehl A., Karst U., Broekmann P., Waldvogel S. . ‘Leaded Bronze: An Innovative Lead Substitute for Cathodic Electrosynthesis.’ ChemElectroChem 5, No. 2: 247–252. doi: 10.1002/celc.201701061.
  • Beil SB, Mueller T, Sillart SB, Franzmann P, Bomm A, Holtkamp M, Karst U, Schade W, Waldvogel SR. . ‘Active Molybdenum-Based Anode for Dehydrogenative Coupling Reactions.’ Angewandte Chemie International Edition 57, No. 9: 2450–2454. doi: 10.1002/anie.201712718.
  • Traeger L, Gallitz I, Sekhri R, Baeumer N, Kuhlmann T, Kemming C, Holtkamp M, Mueller J, Karst U, Canonne-Hergaux F, Muckenthaler MU, Bloch DB, Olschewski A, Bartnikas TB, Steinbicker AU. . ‘ALK3 undergoes ligand-independent homodimerization and BMP-induced heterodimerization with ALK2.’ Free Radical Biology and Medicine 129: 127–137. doi: 10.1016/j.freeradbiomed.2018.09.021.
  • OetermannS, Vivod R, Hiessl S, Hogeback J, Holtkamp M, Karst U, Steinbuechel A. . ‘Histidine at Position 195 is Essential for Association of Heme-b in Lcp1(VH2).’ Earth Systems and Environment 2, No. 1: 5–14. doi: 10.1007/s41748-018-0041-2.

  • Dierkes T., Seidel S., Benndorf C., Heletta L., de Oliveira Junior M., Holtkamp M., Karst U., Block T., Jüstel T., Eckert H., Pöttgen R. . ‘Mixed europium valence in Eu0.937Ba8[BN2]6 – Structure and spectroscopic behavior.’ Solid State Sciences 70, No. null: 86–92. doi: 10.1016/j.solidstatesciences.2017.06.002.
  • Vásquez-Céspedes S., Holtkamp M., Karst U., Glorius F. . „Reusable and Magnetic Palladium and Copper Oxide Catalysts in Direct ortho and meta Arylation of Anilide Derivatives.“ SYNLETT 28, No. null: 2754–2759. doi: 10.1055/s-0036-1589007.
  • Thyssen GM, Holtkamp M, Kaulfürst-Soboll H, Wehe CA, Sperling M, von Schaewen A, Karst U. . ‘Elemental bioimaging by means of LA-ICP-OES: investigation of the calcium, sodium and potassium distribution in tobacco plant stems and leaf petioles.’ Metallomics 9, No. 6: 676–684. doi: 10.1039/c7mt00003k.

  • Birka M., Roscher J., Holtkamp M., Sperling M., Karst U. . ‘Investigating the stability of gadolinium based contrast agents towards UV radiation.’ Water Research 91, No. null: 244–250. doi: 10.1016/j.watres.2016.01.012.

  • Ricciardi R., Huskens J., Holtkamp M., Karst U., Verboom W. . ‘Dendrimer-encapsulated palladium nanoparticles for continuous-flow Suzuki-Miyaura cross-coupling reactions.’ ChemCatChem 7, No. 6: 936–942. doi: 10.1002/cctc.201500017.

  • Wehe CA, Pieper I, Holtkamp M, Thyssen GM, Sperling M, Schwerdtle T, Karst U. . ‘On-line species-unspecific isotope dilution analysis in the picomolar range reveals the time- and species-depending mercury uptake in human astrocytes.Analytical and Bioanalytical Chemistry 406, No. 7: 1909. doi: 10.1007/s00216-013-7608-4.
  • Nowak S, Gesell M, Holtkamp M, Sperling M, Karst U, Buscher W. . ‘Low Gas Flow Inductively Coupled Plasma Optical Emission Spectrometry for the Analysis of Food Samples after Microwave Digestion.’ Talanta 129: 575–578. doi: 10.1016/j.talanta.2014.06.045.
  • Pieper I., Wehe C., Bornhorst J., Ebert F., Leffers L., Holtkamp M., Höseler P., Weber T., Mangerich A., Bürkle A., Karst U., Schwerdtle T. . ‘Mechanisms of Hg species induced toxicity in cultured human astrocytes: Genotoxicity and DNA-damage response.’ Metallomics 6, No. 3: 662–671. doi: 10.1039/c3mt00337j.

  • Hoerr V., Tuchscherr L., Huve J., Nippe N., Loser K., Glyvuk N., Tsytsyura Y., Holtkamp M., Sunderkotter C., Karst U., Klingauf J., Peters G., Loffler B., Faber C. . ‘Bacteria tracking by in vivo magnetic resonance imaging.’ BMC Biology 11, No. 63. doi: 10.1186/1741-7007-11-63.
  • Holtkamp M, Elseberg T, Wehe CA, Sperling M, Karst U. . ‘Complexation and oxidation strategies for improved TXRF determination of mercury in vaccines.’ J. Anal. At. Spectrom. 28: 719–723. doi: 10.1039/C3JA00002H.
  • Stange R., Kronenberg D., Timmen M., Everding J., Hidding H., Eckes B., Hansen U., Holtkamp M., Karst U., Pap T., Raschke M.J. . ‘Age-related bone deterioration is diminished by disrupted collagen sensing in integrin α2β1 deficient mice.’ Bone 56, No. 1: 48–54. doi: 10.1016/j.bone.2013.05.003.
  • Munirathinam R., Ricciardi R., Egberink R., Huskens J., Holtkamp M., Wormeester H., Karst U., Verboom W. . ‘Gallium-containing polymer brush film as efficient supported Lewis acid catalyst in a glass microreactor.’ Beilstein Journal of Organic Chemistry 9, No. null: 1698–1704. doi: 10.3762/bjoc.9.194.

  • Holtkamp M, Wehe CA, Blaske F, Holtschulte C, Sperling M, Karst U. . ‘Nitrogen purged TXRF for the quantification of silver and palladium.’ Journal of Analytical Atomic Spectrometry 27: 1799–1802. doi: 10.1039/c2ja30117b.

  • Wehe CA, Bornhorst J, Holtkamp M, Sperling M, Galla H-J, Schwerdtle T, Karst U. . ‘Fast and low sample consuming quantification of manganese in cell nutrient solutions by flow injection ICP-QMS.’ Metallomics 3, No. 12: 1291–1296. doi: 10.1039/c1mt00170a.
  • Petroutsos D, Busch A, Janssen I, Trompelt K, Bergner SV, Weinl S, Holtkamp M, Karst U, Kudla J, Hippler M. . ‘THE CHLOROPLAST CALCIUM SENSOR CAS IS REQUIRED FOR PHOTOPROTECTION IN CHLAMYDOMONAS REINHARDTII.’ European Journal of Phycology 46: 85. doi: 10.1080/09670262.2011.613190.
  • Petroutsos D, Busch A, Janssen I, Trompelt K, Bergner SV, Weinl S, Holtkamp M, Karst U, Kudla J, Hippler M. . ‘The Chloroplast Calcium Sensor CAS Is Required for Photoacclimation in Chlamydomonas reinhardtii.’ Plant Cell 23, No. 8: 2950–2963. doi: 10.1105/tpc.111.087973.
  • Telgmann L.; Holtkamp M.; Künnemeyer J.; Gelhard C.; Hartmann M.; Klose A.; Sperling M.; Karst U. . ‘Simple and rapid quantification of gadolinium in urine and blood plasma samples by means of total reflection X-ray fluorescence (TXRF).’ Metallomics 3, No. 10: 1035–1040. doi: 10.1039/c1mt00054c.

  • Lux SF, Nowak S, Terborg L, Holtkamp M, Kramer E, Schappacher FM, Rodehorst U, Gallasch TW, Meyer HW, Karst U, Winter M. . ‘Application of LA-ICP-MS/LA-ICP-OES and ICP-OES for the determination of impurities in Li-Ion battery compounds.’ Electrochemical Society - 218th ECS Meeting Abstracts 2010, MA 2010-02 1: 66.
  • Ciarimboli G, Deuster D, Knief A, Sperling M, Holtkamp M, Edemir B, Pavenstädt H, Lanvers-Kaminsky C, am Zehnhoff-Dinnesen A, Schinkel AH, Koepsell H, Jürgens H, Schlatter E. . ‘Organic cation transporter 2 mediates cisplatin-induced oto- and nephrotoxicity and is a target for protective interventions.American Journal of Pathology 176, No. 3: 1169–1180. doi: 10.2353/ajpath.2010.090610.
  • Wilken A, Janzen R, Holtkamp M, Nowak S, Sperling M, Vogel M, Karst U. . ‘Investigation of the interaction of Mercurochrome® constituents with proteins using liquid chromatography/mass spectrometry.’ Analytical and Bioanalytical Chemistry 397, No. 8: 3525–3532. doi: 10.1007/s00216-010-3842-1.