Publikationen
- Daniel, P.-M., Jochen, S., Manuel, D., Broder, R., Miguel, Á.R.-C., Manuel, B.-M., Volker, S. und Juan, S., . Bioprospecting c-di-GMP activated exopolysaccharides in bacteria: [preprint]. doi: 10.1101/2025.09.12.675316.
- Broeker, J. und Schmid, J., . Engineering microbial exopolysaccharides for food applications: Current Opinion in Biotechnology, 95, S. 103339. doi: 10.1016/j.copbio.2025.103339.
- Pia Lanvers, Jannis Bröker, Jochen Schmid, . Clinical-type dextran: A review on process and enzyme engineering strategies to control molecular weight distribution: Carbohydrate Polymers, 364, Artikel 123783. doi: 10.1016/j.carbpol.2025.123783.
- Zander, M., Schmid, J. und Johannes, K., . Implementation of Spore Display in Paenibacillus polymyxa with Different Hydrolytic Enzymes: Microorganisms, 12(7), S. 1438. doi: 10.3390/microorganisms12071438.
- Ravagnan, G. und Schmid, J., . Promising non-model microbial cell factories obtained by genome reduction: Frontiers in Bioengineering and Biotechnology, 12 doi: 10.3389/fbioe.2024.1427248.
- Schilling, J. und Schmid, J., . Comprehensive rheological analysis of structurally related acetan-like heteroexopolysaccharides from two Kozakia baliensis strains in surfactants and galactomannan blends: New Biotechnology, 82, S. 75–84. doi: 10.1016/j.nbt.2024.05.003.
- Ravagnan, G., Lesemann, J., Müller, M.-F., Poehlein, A., Daniel, R., Noack, S. und Kabisch and Jochen Schmid, J., . Genome reduction in Paenibacillus polymyxa DSM 365 for chassis development: Frontiers in Bioengineering and Biotechnology, 12 doi: 10.3389/fbioe.2024.1378873.
- Meliawati, M., C. Volke, D., I. Nikel, P. und Schmid, J., . Engineering the carbon and redox metabolism of Paenibacillus polymyxa for efficient isobutanol production: Microbial Biotechnology, 17(3), Artikel e14438. doi: 10.1111/1751-7915.14438.
- Giulia, R., Meliawati, M. und Jochen, S., . CRISPR-Cas9-Mediated Genome Editing in Paenibacillus polymyxa. In: Braman, Jeffrey und Carl Hrsg. Methods in Molecular Biology, Band 2760: Synthetic Biology, Methods and Protocols . New York: Humana Press. S. 267–280. doi: 10.1007/978-1-0716-3658-9_16.
- Wünsche, J., Brüggemann, H., Gansbiller, M. und Schmid, J., . Acetan-like heteropolysaccharide production by various Kozakia baliensis strains: Characterization and further insights: International Journal of Biological Macromolecules, 253(4) doi: 10.1016/j.ijbiomac.2023.127097.
- Schilling, C., Gansbiller, M., Rühmann, B. und Sieber and Jochen Schmid, V., . Rheological characterization of artificial Paenan compositions produced by Paenibacillus polymyxa DSM 365: Carbohydrate Polymers, 320, Artikel 121243. doi: 10.1016/j.carbpol.2023.121243.
- Wünsche, J. und Schmid, J., . Acetobacteraceae as exopolysaccharide producers: Current state of knowledge and further perspectives.: Frontiers in Bioengineering and Biotechnology, 11:1166618 doi: 10.3389/fbioe.2023.1166618.
- Christoph, S., Leesa, J.K., Finn, L.A., Broder, R., Jochen, S. und Volker, S., . CRISPR-Cas9 driven structural elucidation of the heteroexopolysaccharides from Paenibacillus polymyxa DSM 365: Carbohydrate Polymers, 120763 doi: 10.1016/j.carbpol.2023.120763.
- Meliawati, M., Gansbiller, M. und Schmid, J., . Hyaluronic Acid (Hyaluronan). In: H.A. Bernd und W. David Hrsg. Microbiology Monographs, Band 37: Microbial Production of High-Value Products. Cham: Springer Nature. S. 159–184. doi: 10.1007/978-3-031-06600-9_7.
- Meliawati, M., May, T., Eckerlin, J., Heinrich, D., Herold, A. und Schmid, J., . Insights in the complex DegU, DegS, Spo0A regulation system of Paenibacillus polymyxa by CRISPR-Cas9-based targeted point mutations: Applied and Environmental Microbiology, 88(11), S. e00164-2. doi: 10.1128/aem.00164-22.
- Mweliawati, M., Teckentrup, C. und Schmid, J., . CRISPR-Cas9-mediated Large Cluster Deletion and Multiplex Genome Editing in Paenibacillus polymyxa: ACS Synthetic Biology, 2022(11 / 1), S. 77–84. doi: 10.1021/acssynbio.1c00565.
- Schilling, C., Klau, LJ., Aachmann, FL., Rühmann, B., Schmid, J. und Sieber, V., . Structural elucidation of the fucose containing polysaccharide of Paenibacillus polymyxa DSM 365: Carbohydrate Polymers, 2022(278), Artikel 118951. doi: 10.1016/j.carbpol.2021.118951.
- Blombach, B., Grünberger, A., Centler, F., Wierckx, N. und Schmid, J., . Exploiting unconventional prokaryotic hosts for industrial biotechnology: Trends in Biotechnology, 40(4), S. 385–397. doi: 10.1016/j.tibtech.2021.08.003.
- Rath, T., Rühmann, B., Schmid, J. und Sieber, V., . Systematic optimization of exopolysaccharide production by Gluconacetobacter sp. and use of (crude) glycerol as carbon source: Carbohydrate Polymers, 276, S. 118769. doi: 10.1016/j.carbpol.2021.118769.
- Meliawati, M., Teckentrup, C. und Schmid, J., . CRISPR-Cas9-mediated Large Cluster Deletion and Multiplex Genome Editing in Paenibacillus polymyxa: bioRxiv, 2021 doi: 10.1101/2021.08.06.455192.
- Meliawati, M., Schilling, C. und Schmid, J., . Recent advances of Cas12a applications in bacteria: Applied Microbiology and Biotechnology, 105, S. 2981–2990. doi: 10.1007/s00253-021-11243-9.
- Medina-Cabrera, EV., Gansbiller, M., Rühmann, B., Schmid, J. und Sieber, V., . Rheological characterization of Porphyridium sordidum and Porphyridium purpureum exopolysaccharides: Carbohydrate Polymers, 253, S. 117237. doi: 10.1016/j.carbpol.2020.117237.
- Schilling, C., Koffas, M., Sieber, V. und Schmid, J., . Novel prokaryotic CRISPR-Cas12a based tool for programmable transcriptional activation and repression: ACS Synthetic Biology, 9(12), S. 3353–3363. doi: 10.1021/acssynbio.0c00424.
- Schilling, C., Badri, A., Sieber, V., Koffas, M. und Schmid, J., . Metabolic engineering for production of functional polysaccharides: Current Opinion in Biotechnology, 66, S. 44–51. doi: 10.1016/j.copbio.2020.06.010.
- Sieber, V. und Schmid, J.a., . Microbial Polysaccharides. In: B.W. David, S. Hermann, S. Klaus-Peter und K. Mattheos Hrsg. Industrial Microbiology. John Wiley & Sons. S. 279–299.
- Medina-Cabrera, V.E., Rühmann, B., Schmid, J. und Sieber, V., . Characterization and comparison of Porphyridium sordidum and Porphyridium purpureum concerning growth characteristics and polysaccharide production: Algal Research, 49, S. 101931. doi: 10.1016/j.algal.2020.101931.
- Medina-Cabrera, EV., Rühmann, B., Schmid, J. und Sieber, V., . Optimization of growth and EPS production in two Porphyridum strains: Bioresource Technology Reports, 11, S. 100486. doi: 10.1016/j.biteb.2020.100486.
- Gansbiller, M., Schmid, J. und Sieber, V., . Rheology of sphingans in EPS-surfactant systems: Carbohydrate Polymers, 248, S. 116778. doi: 10.1016/j.carbpol.2020.116778.
- Schilling, C., Ciccone, R. und Sieber, V.a., . Engineering of the 2,3-butanediol pathway of Paenibacillus polymyxa DSM 365: Metabolic Engineering, xx doi: 10.1016/j.ymben.2020.07.009.
- Schmid, J., . Engineering of Microbial Polysaccharide Structures. In: Ö.A. Duru Hrsg. Microbial Exopolysaccharides: Current Research and Developments. UK: Caister Academic Press. S. 83–98. doi: 10.21775/9781912530267.04.
- Schäper, S., Wendt, H., Bamberger, J., Sieber, V., Schmid, J. und Becker, A., . A bifunctional UDP-sugar 4-epimerase supports biosynthesis of multiple cell surface polysaccharides in Sinorhizobium meliloti.: Journal of Bacteriology, 201 doi: 10.1128/jb.00801-18.
- Gansbiller, M., Schmid, J. und Sieber, V., . In-depth rheological characterization of genetically modified xanthan-variants: Carbohydrate Polymers, 213, S. 236–246. doi: 10.1016/j.carbpol.2019.02.055.
- Valdez, A.L., Babot, J.D., Delgado, O.D. und Fariña, I.J., . Scleroglucan Production by Sclerotium rolfsii ATCC 201126 from Amylaceous and Sugarcane Molasses-Based Media: Promising Insights for Sustainable and Ecofriendly Scaling-Up: Journal of Polymers and the Environment, 27 doi: 10.1007/s10924-019-01546-4.
- Schmid, J. und Sieber, V., . The Bacterial Glycome: From Monomers to Complex Carbohydrate Polymers. In: T.M. Schmidt Hrsg. Reference Module in Life SciencesEncyclopedia of Microbiology (Fourth Edition). Elsevier. S. 409–415. doi: 10.1016/b978-0-12-809633-8.90774-x.
- Harnisch, F., Bahnemann, J., Buyel, J., Centler, F., Classen, T., Dohnt, K., Ebert, E.B., Eyer, K., Grünberger, A., Jandt, U., Jung, S., Kara, S., Krujatz, F., Link, H., Regestein, L., Schmid, J. und Tischler, D., . Rechte und Pflichten von akademischen Nachwuchsführungskräften. DECHEMA.
- Schmid, J. und Sieber, V., . Fermentative Production of Microbial Exopolysaccharides. In: M. Gustavo, G. Vijai, S. Brahma und G. Nicholas Hrsg. Bioprocessing for Biomolecules Production. unbekannt / n.a. / unknown. S.00. doi: 10.1002/9781119434436.ch7.
- Schmid, J., Rühmann, B., Sieber, V., Romero-Jiménez, L., Sanjuán, J. und Pérez-Mendoza, D., . Screening of c-di-GMP-Regulated Exopolysaccharides in Host Interacting Bacteria. In: C.M. López-Baena Hrsg. Methods in Molecular Biology Host-Pathogen Interactions: Methods and Protocols . Springer VDI Verlag. S. 263–275. doi: 10.1007/978-1-4939-7604-1_21.
- Rütering, M., Schmid, J., Gansbiller, M., Braun, A., KLeinen, J., Schilling, M. und Sieber, V., . Rheological characterization of the exopolysaccharide Paenan in surfactant systems.: Carbohydrate Polymers, 181, S. 719–726. doi: 10.1016/j.carbpol.2017.11.086.
- Schmid, J., . Recent insights in microbial exopolysaccharide biosynthesis and engineering strategies: Current Opinion in Biotechnology, 53, S. 130–136. doi: 10.1016/j.copbio.2018.01.005.
- Schmid, J., . Divining sugar substrates: Nature Chemical Biology, 14, S. 1071–1072. doi: 10.1038/s41589-018-0165-6.
- Schmid, J. und Harnisch, F., . Das neue Wissenschaftszeitvertragsgesetz: Intention und Status quo!?: BIOspektrum, 23(2), S. 119–119. doi: 10.1007/s12268-017-0773-9.
- Funk, I., Rimmel, N., Schorsch, C., Sieber, V. und Schmid, J., . Production of dodecanedioic acid via biotransformation of low cost plant-oil derivatives using Candida tropicalis: Journal of Industrial Microbiology & Biotechnology, 44(10), S. 1491–1502. doi: 10.1007/s10295-017-1972-6.
- Funk, I., Sieber, V. und Schmid, J., . Effects of glucose concentration on 1,18-cis-octadec-9-enedioic acid biotransformation efficiency and lipid body formation in Candida tropicalis: Scientific Reports, 7(1) doi: 10.1038/s41598-017-14173-7.
- Koenig, S., Rühmann, B., Sieber, V. und Schmid, J., . Quantitative assay of β-(1,3)–β-(1,6)–glucans from fermentation broth using aniline blue: Carbohydrate Polymers, 174, S. 57–64. doi: 10.1016/j.carbpol.2017.06.047.
- Harnisch, F. und Schmid, J., . Editorial to Special Issue of Engineering in Life Sciences Emerging biotechnologies viewed by emerging bioengineers (EBEB): Engineering in Life Sciences, 17(1), S. 4–5. doi: 10.1002/elsc.201600235.
- Rütering, M., Cress, BF., Schilling, M., Rühmann, B., Koffas, M.A., Sieber, V. und Schmid, J., . Tailor-made exopolysaccharides - CRISPR-Cas9 mediated genome editing in Paenibacillus polymyxa: Synthetic Biology, 2(1), S. ysx007. doi: 10.1093/synbio/ysx007.
- Schmid, J., Fariña, I.J., Rehm, B. und Sieber, V. Hrsg., . Microbial Exopolysaccharides: From Genes to Applications. Frontiers Media. doi: 10.3389/978-2-88919-843-6.
- Schmid, J., Fariña, I.J. und Rehm, B.a., . Editorial: Microbial Exopolysaccharides: From Genes to Applications.: Frontiers in Microbiology, 6 doi: 10.3389/fmicb.2016.00308.
- Schmid, J., Heider, D., Wendel, J.N. und Sperl, N.a., . Bacterial Glycosyltransferases: Challenges and Opportunities of a Highly Diverse Enzyme Class Toward Tailoring Natural Products.: Frontiers in Microbiology, 7, S. 182. doi: 10.3389/fmicb.2016.00182.
- Rühmann, B., Schmid, J. und Sieber, V., . Automated Modular High Throughput Exopolysaccharide Screening Platform Coupled with Highly Sensitive Carbohydrate Fingerprint Analysis.: Journal of Visual Experiments, 110, S. e53249. doi: 10.3791/53249.
- Pick, A. und Schmid, J., . Katalytische Kaskadenreaktionen: Chemie Ingenieur Technik, 88(9), S. 1385–1385. doi: 10.1002/cite.201650471.
- Funk, I., Schmid, J. und Sieber, V., . Enhanced Bioconversion Efficiency of Fatty Acids towards α,ω‐Dicarboxylic Acids via Bioprocess Engineering: Chemie Ingenieur Technik, 88(9), S. 1243–1243. doi: 10.1002/cite.201650097.
- Schmid, J., . Development of a Chassis Organism for the Heterologous Expression of Exopolysaccharide-Encoding Operons: Chemie Ingenieur Technik, 88(9), S. 1393–1393. doi: 10.1002/cite.201650383.
- Rütering, M., Schmid, J., Rühmann, B., Schilling, M. und Sieber, V., . Controlled production of polysaccharides-exploiting nutrient supply for levan and heteropolysaccharide formation in Paenibacillus sp.: Carbohydrate Polymers, 148, S. 326–334. doi: 10.1016/j.carbpol.2016.04.074.
- Schmid, J., Huptas, C. und Wenning, M., . Draft Genome Sequence of the Xanthan Producer Xanthomonas campestris LMG 8031.: Genome Announcements, 4(5), S. e01069–16. doi: 10.1128/genomea.01069-16.
- Pick A, B.B., Hemmi R, M. und Schmid J, M.K., . Identification and characterization of two new 5-keto-4-deoxy-D-Glucarate Dehydratases/Decarboxylases.: BMC Biotechnology, 16 (80) doi: 10.1186/s12896-016-0308-3.
- Loscar, E.M., Huptas, C., Wenning, M. und Sieber, V.a., . Draft Genome Sequence of Lysinibacillus xylanilyticus SR-86.: Genome Announcements, 4(6) doi: 10.1128/genomea.01317-16.
- Rühmann, B., Schmid, J. und Sieber, V., . Methods to identify the unexplored diversity of microbial exopolysaccharides.: Frontiers in Microbiology, 6, S. 565. doi: 10.3389/fmicb.2015.00565.
- Schmid, J. und Muffler, K., . Green genetic engineering - The rationale of an opportunity, Grüne Gentechnologie? der Ratio eine Chance: BIOspektrum, 21(4), S. 367. doi: 10.1007/s12268-015-0586-7.
- Schmid, J., Sieber, V. und Rehm, B., . Bacterial exopolysaccharides: biosynthesis pathways and engineering strategies.: Frontiers in Microbiology, 6, S. 496. doi: 10.3389/fmicb.2015.00496.
- Rühmann, B., Schmid, J. und Sieber, V., . High throughput exopolysaccharide screening platform: from strain cultivation to monosaccharide composition and carbohydrate fingerprinting in one day.: Carbohydrate Polymers, 122, S. 212–220. doi: 10.1016/j.carbpol.2014.12.021.
- Schmid, J. und Sieber, V., . Enzymatic transformations involved in the biosynthesis of microbial exo-polysaccharides based on the assembly of repeat units.: ChemBioChem, 16, S. 1141–1147. doi: 10.1002/cbic.201500035.
- Schmid, J. und Muffler, K., . Grüne Gentechnologie - der Ratio eine Chance: BIOspektrum, 21(4), S. 367–367. doi: 10.1007/s12268-015-0586-7.
- Pick, A., Schmid, J. und Sieber, V., . Characterization of uronate dehydrogenases catalysing the initial step in an oxidative pathway.: Microbial Biotechnology, 8(4), S. 633–643. doi: 10.1111/1751-7915.12265.
- Reese, J., Sieber, V., Plank, J., Sperl, N. und Schmid, J., . Effect of biotechnologically modified alginates on LDH structures: Bioinspired, Biomimetic and Nanobiomaterials, 4(3), S. 174–186. doi: 10.1680/bbn.14.00032.
- Blombach, B., Castiglione, K., Haarmann, T. und Schmid, J., . Trends in der Genomeditierung für die industrielle Biotechnologie: BIOspektrum, 21(7), S. 788–790. doi: 10.1007/s12268-015-0645-0.
- Schmid, J., Koenig, S., Pick, A., Steffler, F., Yoshida, S., Miyamoto, K. und and, S.V., . Draft Genome Sequence of Kozakia baliensis SR-745, the First Sequenced Kozakia Strain from the Family Acetobacteraceae.: Genome Announcements, 2(3), S. e00594–14. doi: 10.1128/genomea.00594-14.
- Schmid, J., Koenig, S., Rühmann, B., Rütering, M. und Sieber, V., . Biosynthese und Genomik mikrobieller Polysaccharide: BIOspektrum, 20(3), S. 288–290. doi: 10.1007/s12268-014-0443-0.
- Rühmann, B., Schmid, J. und Sieber, V., . Fast carbohydrate analysis via liquid chromatography coupled with ultra violet and electrospray ionization ion trap detection in 96-well format.: Journal of Chromatography A, 1350, S. 44–50. doi: 10.1016/j.chroma.2014.05.014.
- Schmid, J., Sperl, N. und Sieber, V., . A comparison of genes involved in sphingan biosynthesis brought up to date.: Applied Microbiology and Biotechnology, 98, S. 7719–7733. doi: 10.1007/s00253-014-5940-z.
- Pick, A., Ott, W., Howe, T., Schmid, J. und Sieber, V., . Improving the NADH-cofactor specificity of the highly active AdhZ3 and AdhZ2 from Escherichia coli K-12: Journal of Biotechnology, 189, S. 157–165. doi: 10.1016/j.jbiotec.2014.06.015.
- Schmid, J., Mueller-Hagen, D., Sieber, V. und Meyer, V., . Nucleic and Protein Extraction Methods for Fungal Exopolysaccharide Producers. In: V. Gupta, M. Tuohy, M. Ayyachamy, K. Turner und A. O’Donovan Hrsg. Fungal BiologyLaboratory Protocols in Fungal Biology. New York: Springer VDI Verlag. S. 427–434. doi: 10.1007/978-1-4614-2356-0_39.
- Pick, A., Rühmann, B., Schmid, J. und Sieber, V., . Novel CAD-like enzymes from Escherichia coli K-12 as additional tools in chemical production: Applied Microbiology and Biotechnology, 97(13), S. 5815–5824. doi: 10.1007/s00253-012-4474-5.
- Schmid, J., Meyer, V. und Sieber, V., . Scleroglucan: biosynthesis, production and application of a versatile hydrocolloid: Applied Microbiology and Biotechnology, 91(4), S. 937–947. doi: 10.1007/s00253-011-3438-5.
- Schmid, J., Mueller-Hagen, D., Bekel, T., Funk, L., Stahl, U., Sieber, V. und Meyer, V., . Transcriptome sequencing and comparative transcriptome analysis of the scleroglucan producer Sclerotium rolfsii: BMC Genomics, 11 doi: 10.1186/1471-2164-11-329.
- Schmid, J., Stahl, U. und Meyer, V., . Genetic and Metabolic Engineering in Filamentous Fungi. In: K. Esser Hrsg. Mycota XV: Physiology and Genetics: SELECTED BASIC AND APPLIED ASPECTS, Band 15: Mycota XV: Physiology and Genetics: SELECTED BASIC AND APPLIED ASPECTS. Berlin - Heidelberg: Springer VDI Verlag. S. 377–392. doi: 10.1007/978-3-642-00286-1_18.
- Schwartlander, R., Schmid, J., Brandenburg, B., Katenz, E., Wolfgang, F., Vondran, R., Pless, G., Cheng, X., Pascher, A., Neuhaus, P. und Sauer, IM., . Continuously microscopically observed and process-controlled cell culture within the SlideReactor: Proof of a new concept for cell characterization: Tissue Engineering, 13(1), S. 187–196. doi: 10.1089/ten.2006.0071.
- Schwartlander, R., Schmid, J., Katenz, E., Cheng, X., Pless, G., Modest, D., Vondran, F., Neuhaus, P. und Sauer, I., . The slidereactor - Proof of concept: International Journal of Artificial Organs, 29(5), S. 519.
- Schwartlander, R., Schmid, J., Katenz, E., Cheng, X., Pless, G., Gong, X., Vondran, F., Neuhaus, P. und Sauer, IM., . The slidereactor - Evaluation of a hollow fiber based bioreactor suitable for light microscopy: International Journal of Artificial Organs, 28(9), S. 887. doi: 10.1111/j.1525-1594.2005.29049.x.
- Sauer, I., Schwartlander, R., Schmid, J., Efimova, E., Vondran, F., Kehr, D., Pless, G., Spinelli, A., Brandenburg, B., Hildt, E. und Neuhaus, P., . The SlideReactor - A simple hollow fiber based bioreactor suitable for light microscopy: Artificial Organs, 29(3), S. 264–267. doi: 10.1111/j.1525-1594.2005.29049.x.