Prof. Dr. Nadimpalli Siva Kumar  University of Hyderabad Department of Biochemistry Hyderabad - 500046 India
Email:	drnsk7@yahoo.co.in nsksl@uohyd.ernet.in

Prof. Nadimpalli has more then 22 years of teaching and research experience at the University of Hyderabad. Nine students have so far obtained their PhD degrees under his guidance and four M.Phil. students completed their M.Phil. Several M.Sc students and M.Tech Medical Biotechnology students have carried out their projects under his guidance. The main focus of research in his laboratory is in the field of glyco-biology (plant and animal lectins, plant and animal glycosidases, their structure-function relationships).
Prof. Nadimpalli had developed several new affinity methods for the large scale purification of plant and animal lectins. The major highlights of the research are in the field of lysosomal enzymes and their receptors. Prof. Nadimpalli has extensively collaborated with German scientists of high International repute and made several significant first contributions towards the identification and characterization of mannose-6-phosphate receptor proteins (the lysosomal enzyme sorting receptors), and established that the receptors are evolutionarily conserved proteins. Furthermore by molecular cloning and sequence analysis he established that all the vertebrate proteins have common ligand binding domains with possible conserved functions. Of the 45 peer reviewed publications in the field of glycoproteins (lectins and receptors) 25 are in the field of lysosomal enzymes and their receptors. Current research interests focus on the structure-function relationship of the invertebrate MPR proteins and lysosomal enzymes. Additional interests include to functionally characterize several glycosidase enzymes from plant and animal sources and to understand the function of the lectins purified in the laboratory. The laboratory has the expertise to carry out the following:

1. Preparation of affinity gels and purification of biologically important proteins
2. Cell culture, metabolic labelling of cells
3. Characterization of purified proteins, radio-iodination of proteins
4. Glycosidase enzyme assays
5. Molecular cloning (PCR)
6. Basic laboratory infrastructure for the above studies

Additional:
Well versed with German language, and has extensive collaboration with German Scientists and worked at Universities of Würzburg, Göttingen, Münster, and also at EMBL, Heidelberg. Also collaborated with French scientists.

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