2022

Morris S, Molina-Riquelme I, Barrientos G, Bravo F, Aedo G, Gomez W, Lagos D, Verdejo H, Peischard S, Seebohm G, Psathaki OE, Eisner V*, Busch* KB (2022). Inner mitochondrial membrane structure and fusion dynamics are altered in senescent human iPSC-derived and primary rat cardiomyocytes. Biochim Biophys Acta Bioenerg, 1864(2): 148949

Wu Z, Berlemann LA, Bader V, Sehr DA, Eilers E, Covallero A, Meschede J, Angersbach L, Showkat C, Michaelis JB, Münch C, Rieger B, Namgaladze D, Herrera MG, Fiesel FC, Springer W, Mendes M, Stepien J, Barkovits K, Marcus K, Sickmann A, Dittmar G, Busch KB, Rieder D, Brini M, Tatzelt J, Cali T, Winklhofer KF* (2022). LUBAC assembles a signaling platform at mitochondria for transport of NF-ĸB to the nucleus. EMBO J, 41(24): e112006

Peischard S, Moller M, Disse P, Ho HT, Verkerk AO, Strutz-Seebohm N, Budde T, Meuth SG, Schweizer PA, Morris S, Mucher L, Eisner V, Thomas D, Klingel K, Busch KB and G. Seebohm (2022). Virus-induced inhibition of cardiac pacemaker channel HCN4 triggers bradycardia in human-induced stem cell system. Cell Mol Life Sci, 79(8): 440

Duethorn B, Groll F, Rieger B, Drexler H, Brinkmann H, Kremer L, Stehling M, Borowski MT, Mildner K, Zeuschner D, Zernicka-Goetz M, Stemmler M, Busch KB, Vaquerizas J, and Bedzhov I*(2022) Lima1 mediates the pluripotency control of membrane dynamics and cellular metabolism. Nat Commun, 13(1): 1-19

2021

Rieger B*, Arroum T, Borowski M-T, Villalta J, Busch* KB (2021) Mitochondrial F1FO ATP synthase determines the local proton motive force at cristae rims. EMBO Rep (2021) e52727

Salewskij K, Gross-Thebing T, Ing-Simmons E, Duethorn B, Rieger B, Fan R, Chen R, Govindasamy N, Brinkmann H, Kremer L, Kuempel-Rink N, Mildner K, Zeuschner D, Stehling M, Zwaka TP, Busch KB, Vaquerizas JM, and Bedzhov I. Ronin governs the metabolic capacity of the embryonic lineage for post-implantation development. EMBO Rep (2021) e53048

Bhagawati M, Arroum T, Webeling N, González Montoro A, Mootz HD, and Busch* KB (2021) The receptor subunit Tom20 is dynamically associated with the TOM complex in mitochondria of human cells. MBoC, E21-01-0042, 2021

Weissert V, Rieger B, Morris S, Arroum T, Psathaki OE, Zobel T, Perkins G, and Busch* KB (2021) Inhibition of the mitochondrial ATPase function by IF1 changes the spatiotemporal organization of ATP synthase. BBA Bioenergetics, 1862, 148322

2020

Bhagawati M, Hoffmann S, Katharina S. Höffgen KS, Piehler J, Busch KB, and Mootz HD (2020). In cellulo protein semi-synthesis from endogenous and exogenous fragments using the ultra-fast split Gp41-1 intein. Angew Chem Int Ed Engl, 59,2–11

Peischard S, Tran Ho H, Ilaria Piccini I, Strutz-Seeboh N, Röpke A, Ivan Liashkovich I, Gosain H, Rieger B, Klingel K, Eggers B, Marcus K, Linke WA, Müller FU, Ludwig S, Greber B, Busch KB, and Seebohm G. (2020) The first versatile human iPSC-based model of ectopic virus induction allows new insights in RNA-virus disease. Sci Rep 10: 16804

Rieger B, Thierbach S, Ommer M, Dienhart SFV, Fetzner S, Busch* KB (2020) Pseudomonas Quinolone Signal molecule PQS behaves like a B Class inhibitor at the IQ site of mitochondrial complex I, FASEB Bioadv 2, 188-202

Busch KB (2020) Inner mitochondrial membrane compartmentalization: Dynamics across scales. Intern. J. Biochem. and Cell Biology 120: 105694

Lyamzaev KG, Panteleeva AA, Karpukhina AA, Galkin II, Popova EN, Pletjushkina OY, Rieger B, Busch KB, Mulkidjanian AY, Chernyak BV (2020) Novel fluorescent mitochondria-targeted probe MitoCLox reports lipid peroxidation in response to oxidative stress in vivo. Oxidative Medicine and Cellular Longevity, 10:2020:3631272

2019

Rieger* B, Krajčová A, Duwe P, Busch* KB (2019) ALCAT1 overexpression affects supercomplex formation and increases ROS in respiring mitochondria. Oxidative Medicine and Cellular Longevity,

Salewskij K, Rieger B, Hager F, Arroum T, Duwe P, Villalta J, Colgiati S, Richter CP, Psathaki OE, Enriquez JA, Dellmann T, Busch* KB (2019) The spatio-temporal organization of mitochondrial F1FO ATP synthase in cristae depends on its activity mode. Biochim Biophys Acta Bioenerg, 1861(1):148091

Klotz L, Eschborn M, Lindner M, Liebmann M, Herold M, Janoschka C, Torres Garrido B, Schulte-Mecklenbeck A, Gross CC, Breuer J, Hundehege P, Posevitz V, Pignolet B, Nebel G, Glander S, Freise N, Austermann J, Wirth T, Campbell GR, Schneider-Hohendorf T et al. (2019) Teriflunomide treatment for multiple sclerosis modulates T cell mitochondrial respiration with affinity-dependent effects. Sci Transl Med 11 (490)

Older

Appelhans T and Busch *KB (2018) Multi-color localization microscopy of single membrane proteins in organelles of live mammalian cells. J Vis Exp. 136

Liebmann M, Hucke S, Koch K, Eschborn M, Ghelman J, Chasan AI, Glander S, Schadlich M, Kuhlencord M, Daber NM, Eveslage M, Beyer M, Dietrich M, Albrecht P, Stoll M, Busch KB, Wiendl H, Roth J, Kuhlmann T, Klotz L (2018b) Nur77 serves as a molecular brake of the metabolic switch during T cell activation to restrict autoimmunity. Proc Natl Acad Sci U S A 115: E8017-E8026

Rieger B, Shalaeva DN, Söhnel A-CC, Kohl W, Duwe P, Mulkidjanian AY & Busch* KB (2017) Lifetime imaging of GFP at CoxVIIIa reports respiratory supercomplex assembly in live cells. Sci Rep 7, 46055.

Söhnel AC, Kohl W, Gregor I, Enderlein J, Rieger B, Busch* KB (2016) Probing of protein localization and shuttling in mitochondrial microcompartments by FLIM with sub-diffraction resolution, BBA Bioenergetics 1857:1290-1299.

Drees C, Raj AN, Kurre R, Busch KB, Haase M, and J Piehler J (2016) Engineered upconversion particles for resolving protein interactions inside living cells Angew Chem Int Ed Engl. 55:116668-72. Internat.Ed.

Beinlich FR, Drees C, Piehler J, & Busch* KB (2015) Shuttling of PINK1 between Mitochondrial Microcompartments Resolved by Triple-Color Superresolution Microscopy. (Translated from eng) ACS chemical biology 10(9):1970-1976 (in eng).

Orban-Glaß I, Voskoboynikova N., Busch KB, Klose D, Rickert C, Mosslehy W, Roder F, Wilkens V, Piehler J, Engelhard M, Steinhof, H J, Klare JP (2015) Clustering and Dynamics of Phototransducer Signaling Domains Revealed by Site-Directed Spin Labeling Electron Paramagnetic Resonance on SRII/HtrII in Membranes and Nanodiscs. Biochemistry 54:349-362.

Rieger, B., Junge W, Busch* KB (2014) Lateral pH-gradient between OXPHOS proton-pump and FOF1-ATP-synthase in folded cristae membranes of active mammalian mitochondria. Nature communications 5:3103. https://doi.org/10.1038/ncomms4103

Wilkens V, Kohl W, Busch* KB (2013) Restricted diffusion of OXPHOS complexes in dynamic mitochondria delays their exchange between cristae and engenders a transitory mosaic distribution. Journal of Cell Science 126: 103-116.

Wilmes S, Staufenbiel M, Lisse D, Richter CP, Beutel O, Busch KB, Hess ST, Piehler J. (2012) Triple-color super-resolution imaging of live cells: resolving submicroscopic receptor organization in the plasma membrane. Angewandte Chemie 51(20):4868-4871 (in eng).

Appelhans T, Richter CP, Wilkens V, Hess ST, Piehler J, Busch* KB (2012) Nanoscale organization of mitochondrial microcompartments revealed by combining tracking and localization microscopy. Nano letters 12: 610-616. https://doi.org/10.1021/nl203343a

Lisse D, Wilkens V, You C, Busch KB, Piehler J (2011) Selective targeting of fluorescent nanoparticles to proteins inside live cells. Angewandte Chemie 50: 9352-9355 (in eng).

Muster B, Kohl W, Wittig I, Strecker V, Joos F, Haase W, Bereiter-Hahn J, and Busch* K (2010) Respiratory chain complexes in dynamic mitochondria display a patchy distribution in life cells. PLoS One 5: e11910.

Busch KB, Bereiter-Hahn J, Wittig I, Schägger H, and Jendrach M. (2006). Mitochondrial dynamics generate equal distribution but patchwork localisation of respiratory Complex I. Molecular Membrane Biology 23 (6), 1-12.

Busch KB, Piehler J, and H. Fromm (2000). Dissection of nucleotide binding to plant succinic semialdhyde dehydrogenase by fluorescence spectroscopy and surface plasmon resonance. Biochemistry 39 (33), 10110-7.

Busch K, and H. Fromm (1999). Plant succinic semialdehyde dehydrogenase: cloning, purification, localization in mitochondria, and regulation by adenine nucleotides. Plant Physiol. 21, 589-597.

Busch K, and H. Ninnemann (1997). The controlling influence of ADP, ATP and Mg2+ on the activities of adenylate kinase, ADP/ATP translocator, ATP synthase and the mitochondrial respiration in plants (Solanum tuberosum L.). Plant Sci. 128, 85-95.

Busch K, and H. Ninnemann (1996). Characterization of adenylate kinase in intact mitochondria of fertile and male sterile potato (Solanum tuberosum L.). Plant Sci. 116: 1-8.

Busch K, and H. Ninnemann (1996) The influence of magnesium on mitochondrial respiration and enzyme activities. 9th European Bioenergetics Conference, Biochim. Biophys. Acta EBEC Short Reports 9, 161.

Sukhorukov, V.M., Dikov, D., Busch, K., Strecker, V., Wittig, I., and Bereiter-Hahn, J. (2010) Determination of protein mobility in mitochondrial membranes of living cells. BBA., 1789:2022-32

Schilde-Rentschler L, Busch KB, Schweis A, and Ninnemann H (1995). Somatic hybrids for the study of nuclear-cytoplasmic interaction in Solanum tuberosum. Advanc. Plant Breed. 18: 37-48.

Reviews

Busch KB (2018) Respiration: Life without complex I. Curr. Biol. 28 (10) R616-R618

Appelhans T, Busch KB (2017) Dynamic Imaging of Mitochondrial Membrane Proteins in Specific Sub-Organelle Membrane Locations. Biophysical Reviews 9(4): 345-352.

Busch KB, Kowald A, and Spelbrink J. (2014) Quality matters. How does mitochondrial network dynamics and quality control impact on mtDNA integrity. Philos Trans R Soc Lond B Biol Sci 369:1646

Busch KB, Deckers-Hebestreit G, Hanke GT, & Mulkidjanian AY (2013) Dynamics of bioenergetic microcompartments. Biol Chem 394 (2):163-188.

Busch KB and R. Tampé (2001). Single molecule research on surfaces: from analytics to construction and back. J. Biotechnol. 82, 3-24.

Book Chapters

Rieger B and Busch* KB. Protein supercomplex recording in living cells via position-specific fluorescence lifetime sensors, in: Methods in Molecular Biology, Springer Protocols. Mitochondrial Medicine, 2nd edition, V. Weissig, M. Edeas, Editors. Humana Press, Springer New York Heidelberg Dordrecht London, 2020, 2275, 301-314.

Appelhans T, Busch* KB (2017) Single molecule tracking and localization of mitochondrial protein complexes, Methods in Molecular Biology, Springer Protocols. Practical Protocols, 2nd edition, D. Mokranjac, F. Perocchi, Editors. Humana Press, Springer New York Heidelberg Dordrecht London, 2019, 1567: 273-291.