Group of Prof. Dr. Bernt Krebs
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Dr. Michael Merkel

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Bioinorganic Group (Iron)

E-mail: merkel@chem.ubc.ca

Career

  • since 09/2004: Postdoctoral Fellow (see stays abroad)
  • 29.04.2004: Ph.D. Inorganic Chemistry, WWU Münster
  • 27.03.2001: Diploma Chemistry, WWU Münster
  • 21.10.1998: Prediploma Chemistry, WWU Münster
  • 10/1996: Start of Chemistry Studies
  • 10/1995 - 10/1996: Alternative Civilian Service
  • 30.05.1995: Abitur, Wilhelm-Hittorf-Gymnasium, Münster

Fellowships

Stays Abroad and Internships

  • since 09/2004: Postdoctoral Fellow in the Group of Prof. Dr. Chris Orvig, University of British Columbia, Vancouver, Canada.
    Subject: Medicinal Inorganic Chemistry
  • 04/2000 - 06/2000: Bayer AG, Leverkusen, Germany; Supervisor: Dr. Hanno Brümmer
  • 01/2000 - 03/2000: Research Appointment, West Virginia Univesity, WV, U.S.A.; Supervisor: Prof. Dr. Jeffrey L. Petersen

Publications

  • Chelate Ring Size Variations and their Effects on Coordination Chemistry and Catechol Dioxygenase Reactivity of Iron(III) complexes
    M. Merkel, M. Pascaly, B. Krebs, J. Astner, S. P. Foxon, S. Schindler
    Inorg. Chem. 2005, angenommen.
  • Less Symmetrical Dicopper(II) Complexes as Catechol Oxidase Models - An Adjacent Thioether Group Increases Catecholase Activity
    M. Merkel, N. Möller, M. Piacenza, S. Grimme, A. Rompel, B. Krebs
    Chem. Eur. J. 2005, 11, 1201-1209.
  • Zinc Complexes from Bromo Substituted Tris[(2-pyridyl)methyl]amine Ligands. Influence of Sterically Demanding Substituents on Coordination Geometry
    D. Schnieders, M. Merkel, S. M. Baldeau, B. Krebs
    Z. Anorg. Allg. Chem. 2004, 630, 1210-14.
  • Catechol oxidase and biomimetic approaches
    B. Krebs, M. Merkel, A. Rompel
    J. Argent. Chem. Soc. 2004, 92, 1-15.
  • Four Isotypic Highly Coordinated Lanthanide Complexes of the Tripodal Ligand Bis[(2-pyridyl)methyl][(1-methylimidazol-2-yl)methyl]amine
    M. Merkel, M. Pascaly, C. Köster, B. Krebs
    Z. Naturforsch. 2004, 59b, 216-20.
  • Structural snapshots of a dynamic coordination sphere in model complexes for catechol 1,2-dioxygenases
    M. Merkel, D. Schnieders, S. M. Baldeau, B. Krebs
    Eur. J. Inorg. Chem. 2004, 783-90.
  • Synthesis and Characterization of the first (1,2-Benzenedithiolato)iron(III) Complexes with Tripodal Ligands
    M. Merkel, M. Pascaly, M. Wieting, M. Duda, A. Rompel
    Z. Anorg. Allg. Chem. 2003, 629, 2216-21.
  • Novel iron(III) complexes with phenolate containing tripodal tetradentate ligands as model systems for catechol dioxygenases
    M. Merkel, F. K. Müller, B. Krebs
    Inorg. Chim. Acta, 2002, 337, 308-16.


Poster Presentations und Talks

  • Chelate Ring Size Variations in Catechol Dioxygenase Models
    M. Merkel, J. Astner, S. Schindler, B. Krebs
    EUROBIC 7, Garmisch-Partenkirchen, Germany, 2004.
  • Partieller Ligandenaustausch in Modellen für Catechol-1,2-Dioxygenasen
    M. Merkel, B. Krebs
    GDCh Jahrestagung, München, Germany, 2003.
  • Explorations of Alternative Routes for the Preparation of Electrophilic Group IV Metal Complexes Featuring Chelating Diamido Ligands
    A. R. Morgan, M. Merkel, M. Kloskowski, J. L. Petersen
    Gordon Research Conference on Organometallics, Newport, RI, U.S.A. 2002.
  • Model Complexes for Intra- and Extradiol Cleaving Catechol Dioxygenases
    K. Zurlinden, M. Merkel, B. Krebs
    EUROBIC 6, Lund, Schweden, 2002.
  • Evidence of a Dynamic Coordination Sphere in Models for Protocatechuate 3,4-Dioxygenase
    M. Merkel, K. Zurlinden, B. Krebs
    EUROBIC 6, Lund, Schweden, 2002.
  • Talk: Model complexes for intradiol cleaving catechol dioxygenases
    M. Merkel
    Symposium des Internationalen Graduiertenkollegs in Münster, Germany 2002.
  • Mononukleare Eisen(III)-Komplexe als Modellverbindungen für intradiolspaltende Catechol-Dioxygenasen
    K. Zurlinden, M. Merkel, B. Krebs
    GDCh Jahrestagung, Würzburg, Germany, 2001.
  • Mononuclear Iron(III) Complexes Containing N2O2 Donor Ligands as Models for Catechol 1,2-Dioxygenases
    M. Merkel, B. Krebs
    COST D8 Final Meeting, Dublin, Ireland, 2001.